2Q8BA

Structure of the malaria antigen ama1 in complex with a growth-inhibitory antibody
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
334
structure length
292
Chain Sequence
YMGNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLTPVATGNQYLKDGGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPKQYEDRYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody
pubmed doi rcsb
molecule tags Immune system
source organism Plasmodium falciparum
molecule keywords Apical membrane antigen 1
total genus 84
structure length 292
sequence length 334
ec nomenclature
pdb deposition date 2007-06-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2q8bA01
4R19A 4Z0FA 5I25A 2Z8VA 3HMRA 5CT3A 1I8NA 2Y8RA 5CP9A 4A5TS 1W8KA 2F83A 2J8LA 4R1CA 4R1BA 5CSQA 3HMTA 2Q8AA 4Z0DA 5CT2A 4Z09A 5CS3A 2LL4M 1GP9A 2QJ4A 3ZLEA 2YIPA 5CS5A 5EODA 1YXEA 3SRJA 2J8JA 2YIOA 4R1AA 4DURA 3MKPA 2HGFA 3ZWZA 1GMNA 5CS9A 5EOKA 1NK1A 1W81A 2YILA 5CS1A 1BHTA 4UV6A 1HKYA 3SRIA 4UAOA 4APLA 2K13X 4Z0EA 2Q8BA 3HN4A 2Z8WA 4APMA 1GMOA 3SP8A 2X2ZA 2LL3A 3HMSA 5COEA 2QJ2A 1Z40A 4IUAA 5CT1A
chains in the Genus database with same CATH superfamily
4R19A 4Z0FA 5I25A 2Z8VA 3HMRA 5CT3A 1I8NA 2Y8RA 5CP9A 4A5TS 1W8KA 2KL5A 4YIVA 2F83A 2J8LA 4R1CA 4R1BA 5CSQA 3HMTA 2Q8AA 4Z0DA 5CT2A 4Z09A 5CS3A 2LL4M 1GP9A 2QJ4A 3ZLEA 2YIPA 5CS5A 4YIZA 1YXEA 5EODA 3SRJA 2J8JA 2YIOA 4R1AA 4DURA 3MKPA 2HGFA 3ZWZA 1GMNA 5CS9A 5EOKA 1NK1A 1W81A 2YILA 5CS1A 1BHTA 4UV6A 1HKYA 3SRIA 4UAOA 4APLA 2K13X 4Z0EA 2Q8BA 3HN4A 2Z8WA 4APMA 1GMOA 3SP8A 2X2ZA 2LL3A 3HMSA 5COEA 2QJ2A 1Z40A 4IUAA 5CT1A
chains in the Genus database with same CATH topology
4R19A 4Z0FA 5I25A 2Z8VA 3HMRA 5CT3A 1I8NA 2Y8RA 5CP9A 4A5TS 1W8KA 2KL5A 4YIVA 2F83A 2J8LA 4R1CA 4R1BA 5CSQA 3HMTA 2Q8AA 4Z0DA 5CT2A 4Z09A 5CS3A 2LL4M 1GP9A 2QJ4A 3ZLEA 2YIPA 5CS5A 4YIZA 1YXEA 5EODA 3SRJA 2J8JA 2YIOA 4R1AA 4DURA 3MKPA 2HGFA 3ZWZA 1GMNA 5CS9A 5EOKA 1NK1A 1W81A 2YILA 5CS1A 1BHTA 4UV6A 1HKYA 3SRIA 4UAOA 4APLA 2K13X 4Z0EA 2Q8BA 3HN4A 2Z8WA 4APMA 1GMOA 3SP8A 2X2ZA 2LL3A 3HMSA 5COEA 2QJ2A 1Z40A 4IUAA 5CT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4R19 A;  4Z0F A;  5I25 A;  2Z8V A;  3HMR A;  5CT3 A;  1I8N A;  2Y8R A;  5CP9 A;  4A5T S;  1W8K A;  2F83 A;  2J8L A;  4R1C A;  4R1B A;  5CSQ A;  3HMT A;  2Q8A A;  4Z0D A;  5CT2 A;  4Z09 A;  5CS3 A;  2LL4 M;  1GP9 A;  2QJ4 A;  3ZLE A;  2YIP A;  5CS5 A;  5EOD A;  1YXE A;  3SRJ A;  2J8J A;  2YIO A;  4R1A A;  4DUR A;  3MKP A;  2HGF A;  3ZWZ A;  1GMN A;  5CS9 A;  5EOK A;  1NK1 A;  1W81 A;  2YIL A;  5CS1 A;  1BHT A;  4UV6 A;  1HKY A;  3SRI A;  4UAO A;  4APL A;  2K13 X;  4Z0E A;  2Q8B A;  3HN4 A;  2Z8W A;  4APM A;  1GMO A;  3SP8 A;  2X2Z A;  2LL3 A;  3HMS A;  5COE A;  2QJ2 A;  1Z40 A;  4IUA A;  5CT1 A; 
#chains in the Genus database with same CATH topology
 4R19 A;  4Z0F A;  5I25 A;  2Z8V A;  3HMR A;  5CT3 A;  1I8N A;  2Y8R A;  5CP9 A;  4A5T S;  1W8K A;  2KL5 A;  4YIV A;  2F83 A;  2J8L A;  4R1C A;  4R1B A;  5CSQ A;  3HMT A;  2Q8A A;  4Z0D A;  5CT2 A;  4Z09 A;  5CS3 A;  2LL4 M;  1GP9 A;  2QJ4 A;  3ZLE A;  2YIP A;  5CS5 A;  4YIZ A;  1YXE A;  5EOD A;  3SRJ A;  2J8J A;  2YIO A;  4R1A A;  4DUR A;  3MKP A;  2HGF A;  3ZWZ A;  1GMN A;  5CS9 A;  5EOK A;  1NK1 A;  1W81 A;  2YIL A;  5CS1 A;  1BHT A;  4UV6 A;  1HKY A;  3SRI A;  4UAO A;  4APL A;  2K13 X;  4Z0E A;  2Q8B A;  3HN4 A;  2Z8W A;  4APM A;  1GMO A;  3SP8 A;  2X2Z A;  2LL3 A;  3HMS A;  5COE A;  2QJ2 A;  1Z40 A;  4IUA A;  5CT1 A; 
#chains in the Genus database with same CATH homology
 4R19 A;  4Z0F A;  5I25 A;  2Z8V A;  3HMR A;  5CT3 A;  1I8N A;  2Y8R A;  5CP9 A;  4A5T S;  1W8K A;  2KL5 A;  4YIV A;  2F83 A;  2J8L A;  4R1C A;  4R1B A;  5CSQ A;  3HMT A;  2Q8A A;  4Z0D A;  5CT2 A;  4Z09 A;  5CS3 A;  2LL4 M;  1GP9 A;  2QJ4 A;  3ZLE A;  2YIP A;  5CS5 A;  4YIZ A;  1YXE A;  5EOD A;  3SRJ A;  2J8J A;  2YIO A;  4R1A A;  4DUR A;  3MKP A;  2HGF A;  3ZWZ A;  1GMN A;  5CS9 A;  5EOK A;  1NK1 A;  1W81 A;  2YIL A;  5CS1 A;  1BHT A;  4UV6 A;  1HKY A;  3SRI A;  4UAO A;  4APL A;  2K13 X;  4Z0E A;  2Q8B A;  3HN4 A;  2Z8W A;  4APM A;  1GMO A;  3SP8 A;  2X2Z A;  2LL3 A;  3HMS A;  5COE A;  2QJ2 A;  1Z40 A;  4IUA A;  5CT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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