2Q8BA

Structure of the malaria antigen ama1 in complex with a growth-inhibitory antibody
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
334
structure length
292
Chain Sequence
YMGNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLTPVATGNQYLKDGGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPKQYEDRYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Malaria Antigen AMA1 in Complex with a Growth-Inhibitory Antibody
pubmed doi rcsb
molecule tags Immune system
source organism Plasmodium falciparum
molecule keywords Apical membrane antigen 1
total genus 84
structure length 292
sequence length 334
ec nomenclature
pdb deposition date 2007-06-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2q8bA01
1HKYA 2J8LA 4Z0DA 2X2ZA 2Y8RA 4R19A 5EODA 5CSQA 5CP9A 2Z8VA 4Z0FA 4R1BA 5CS1A 4A5TS 2YIPA 2Q8BA 2QJ4A 2K13X 1Z40A 1GMOA 3MKPA 5CS3A 5EOKA 1GMNA 1I8NA 2F83A 4Z0EA 3ZWZA 3HMTA 4DURA 5I25A 2LL3A 1W8KA 5CS5A 3SP8A 3ZLEA 2HGFA 3HN4A 1GP9A 2QJ2A 2Q8AA 2YILA 4UV6A 5CT3A 3SRJA 2LL4M 4Z09A 4R1CA 5CT2A 4APMA 4R1AA 1W81A 3HMSA 5COEA 3SRIA 2J8JA 2Z8WA 1NK1A 1YXEA 1BHTA 2YIOA 3HMRA 4IUAA 5CS9A 4APLA 4UAOA 5CT1A
chains in the Genus database with same CATH superfamily
1HKYA 2J8LA 4Z0DA 4YIZA 2X2ZA 2Y8RA 4R19A 5EODA 5CSQA 5CP9A 2Z8VA 4Z0FA 4R1BA 5CS1A 4A5TS 2YIPA 2Q8BA 2QJ4A 2K13X 1Z40A 1GMOA 3MKPA 5CS3A 5EOKA 1GMNA 1I8NA 2F83A 4Z0EA 3ZWZA 3HMTA 4DURA 5I25A 2LL3A 1W8KA 5CS5A 3SP8A 3ZLEA 2HGFA 2KL5A 3HN4A 1GP9A 2QJ2A 2Q8AA 2YILA 4UV6A 5CT3A 3SRJA 2LL4M 4Z09A 4R1CA 5CT2A 4YIVA 4APMA 4R1AA 1W81A 3HMSA 5COEA 3SRIA 2J8JA 2Z8WA 1NK1A 1YXEA 1BHTA 2YIOA 3HMRA 4IUAA 5CS9A 4APLA 4UAOA 5CT1A
chains in the Genus database with same CATH topology
1HKYA 2J8LA 4Z0DA 4YIZA 2X2ZA 2Y8RA 4R19A 5EODA 5CSQA 5CP9A 2Z8VA 4Z0FA 4R1BA 5CS1A 4A5TS 2YIPA 2Q8BA 2QJ4A 2K13X 1Z40A 1GMOA 3MKPA 5CS3A 5EOKA 1GMNA 1I8NA 2F83A 4Z0EA 3ZWZA 3HMTA 4DURA 5I25A 2LL3A 1W8KA 5CS5A 3SP8A 3ZLEA 2HGFA 2KL5A 3HN4A 1GP9A 2QJ2A 2Q8AA 2YILA 4UV6A 5CT3A 3SRJA 2LL4M 4Z09A 4R1CA 5CT2A 4YIVA 4APMA 4R1AA 1W81A 3HMSA 5COEA 3SRIA 2J8JA 2Z8WA 1NK1A 1YXEA 1BHTA 2YIOA 3HMRA 4IUAA 5CS9A 4APLA 4UAOA 5CT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HKY A;  2J8L A;  4Z0D A;  2X2Z A;  2Y8R A;  4R19 A;  5EOD A;  5CSQ A;  5CP9 A;  2Z8V A;  4Z0F A;  4R1B A;  5CS1 A;  4A5T S;  2YIP A;  2Q8B A;  2QJ4 A;  2K13 X;  1Z40 A;  1GMO A;  3MKP A;  5CS3 A;  5EOK A;  1GMN A;  1I8N A;  2F83 A;  4Z0E A;  3ZWZ A;  3HMT A;  4DUR A;  5I25 A;  2LL3 A;  1W8K A;  5CS5 A;  3SP8 A;  3ZLE A;  2HGF A;  3HN4 A;  1GP9 A;  2QJ2 A;  2Q8A A;  2YIL A;  4UV6 A;  5CT3 A;  3SRJ A;  2LL4 M;  4Z09 A;  4R1C A;  5CT2 A;  4APM A;  4R1A A;  1W81 A;  3HMS A;  5COE A;  3SRI A;  2J8J A;  2Z8W A;  1NK1 A;  1YXE A;  1BHT A;  2YIO A;  3HMR A;  4IUA A;  5CS9 A;  4APL A;  4UAO A;  5CT1 A; 
#chains in the Genus database with same CATH topology
 1HKY A;  2J8L A;  4Z0D A;  4YIZ A;  2X2Z A;  2Y8R A;  4R19 A;  5EOD A;  5CSQ A;  5CP9 A;  2Z8V A;  4Z0F A;  4R1B A;  5CS1 A;  4A5T S;  2YIP A;  2Q8B A;  2QJ4 A;  2K13 X;  1Z40 A;  1GMO A;  3MKP A;  5CS3 A;  5EOK A;  1GMN A;  1I8N A;  2F83 A;  4Z0E A;  3ZWZ A;  3HMT A;  4DUR A;  5I25 A;  2LL3 A;  1W8K A;  5CS5 A;  3SP8 A;  3ZLE A;  2HGF A;  2KL5 A;  3HN4 A;  1GP9 A;  2QJ2 A;  2Q8A A;  2YIL A;  4UV6 A;  5CT3 A;  3SRJ A;  2LL4 M;  4Z09 A;  4R1C A;  5CT2 A;  4YIV A;  4APM A;  4R1A A;  1W81 A;  3HMS A;  5COE A;  3SRI A;  2J8J A;  2Z8W A;  1NK1 A;  1YXE A;  1BHT A;  2YIO A;  3HMR A;  4IUA A;  5CS9 A;  4APL A;  4UAO A;  5CT1 A; 
#chains in the Genus database with same CATH homology
 1HKY A;  2J8L A;  4Z0D A;  4YIZ A;  2X2Z A;  2Y8R A;  4R19 A;  5EOD A;  5CSQ A;  5CP9 A;  2Z8V A;  4Z0F A;  4R1B A;  5CS1 A;  4A5T S;  2YIP A;  2Q8B A;  2QJ4 A;  2K13 X;  1Z40 A;  1GMO A;  3MKP A;  5CS3 A;  5EOK A;  1GMN A;  1I8N A;  2F83 A;  4Z0E A;  3ZWZ A;  3HMT A;  4DUR A;  5I25 A;  2LL3 A;  1W8K A;  5CS5 A;  3SP8 A;  3ZLE A;  2HGF A;  2KL5 A;  3HN4 A;  1GP9 A;  2QJ2 A;  2Q8A A;  2YIL A;  4UV6 A;  5CT3 A;  3SRJ A;  2LL4 M;  4Z09 A;  4R1C A;  5CT2 A;  4YIV A;  4APM A;  4R1A A;  1W81 A;  3HMS A;  5COE A;  3SRI A;  2J8J A;  2Z8W A;  1NK1 A;  1YXE A;  1BHT A;  2YIO A;  3HMR A;  4IUA A;  5CS9 A;  4APL A;  4UAO A;  5CT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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