2Z8V | Genus

Total Genus 80

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	80
sequence length	335
structure length	335
Chain Sequence	NYMGNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLTPVATGNQYLKDGGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCNKDESKRNSMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPKQYEQHLTDYEKIKEGFKNKNASMIKSAFLPTGAFKADRYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__9849436293829825__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__9849436293829825__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/2Z8V/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__9849436293829825__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"9849436293829825","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/2Z8V/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__9849436293829825__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system
source organism	Plasmodium falciparum
publication title	Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition pubmed doi rcsb
molecule keywords	Apical membrane antigen 1
total genus	80
structure length	335
sequence length	335
chains with identical sequence	B
ec nomenclature
pdb deposition date	2007-09-11

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.50.4.10	Alpha Beta	3-Layer(bba) Sandwich	Hepatocyte Growth Factor	Hepatocyte Growth Factor	2z8vA01

1YXEA 3ZWZA 4R1BA 4UAOA 5CS1A 1I8NA 3ZLEA 1Z40A 2HGFA 2Z8VA 3HMRA 5COEA 3SRIA 1GMOA 4R1CA 2YIPA 3HMSA 4R19A 2Z8WA 4Z0FA 1W81A 5I25A 2K13X 4R1AA 2F83A 5EOKA 2LL4M 4UV6A 3HMTA 4Z0DA 2Q8AA 2X2ZA 4IUAA 3SP8A 5CT2A 4DURA 5CT1A 2J8LA 2QJ2A 5EODA 1BHTA 3MKPA 5CS9A 2YIOA 5CS5A 3HN4A 1HKYA 2Y8RA 5CSQA 5CT3A 4Z0EA 4Z09A 2QJ4A 1GMNA 1W8KA 1NK1A 4A5TS 2J8JA 2YILA 1GP9A 3SRJA 4APMA 5CS3A 5CP9A 2LL3A 2Q8BA 4APLA
chains in the Genus database with same CATH superfamily

1YXEA 3ZWZA 4R1BA 4UAOA 5CS1A 1I8NA 3ZLEA 1Z40A 2HGFA 2Z8VA 3HMRA 5COEA 3SRIA 1GMOA 4R1CA 2YIPA 3HMSA 4R19A 2Z8WA 4Z0FA 1W81A 5I25A 4YIVA 2K13X 4R1AA 2F83A 5EOKA 2LL4M 4UV6A 3HMTA 4Z0DA 2Q8AA 2KL5A 2X2ZA 4IUAA 5CT2A 3SP8A 4DURA 5CT1A 2J8LA 2QJ2A 5EODA 1BHTA 3MKPA 5CS9A 2YIOA 5CS5A 3HN4A 1HKYA 2Y8RA 5CSQA 5CT3A 4Z0EA 4Z09A 2QJ4A 1GMNA 1W8KA 4YIZA 1NK1A 4A5TS 2J8JA 2YILA 1GP9A 3SRJA 4APMA 5CS3A 5CP9A 2LL3A 2Q8BA 4APLA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1YXE A;  3ZWZ A;  4R1B A;  4UAO A;  5CS1 A;  1I8N A;  3ZLE A;  1Z40 A;  2HGF A;  2Z8V A;  3HMR A;  5COE A;  3SRI A;  1GMO A;  4R1C A;  2YIP A;  3HMS A;  4R19 A;  2Z8W A;  4Z0F A;  1W81 A;  5I25 A;  2K13 X;  4R1A A;  2F83 A;  5EOK A;  2LL4 M;  4UV6 A;  3HMT A;  4Z0D A;  2Q8A A;  2X2Z A;  4IUA A;  3SP8 A;  5CT2 A;  4DUR A;  5CT1 A;  2J8L A;  2QJ2 A;  5EOD A;  1BHT A;  3MKP A;  5CS9 A;  2YIO A;  5CS5 A;  3HN4 A;  1HKY A;  2Y8R A;  5CSQ A;  5CT3 A;  4Z0E A;  4Z09 A;  2QJ4 A;  1GMN A;  1W8K A;  1NK1 A;  4A5T S;  2J8J A;  2YIL A;  1GP9 A;  3SRJ A;  4APM A;  5CS3 A;  5CP9 A;  2LL3 A;  2Q8B A;  4APL A; 
#chains in the Genus database with same CATH topology
 1YXE A;  3ZWZ A;  4R1B A;  4UAO A;  5CS1 A;  1I8N A;  3ZLE A;  1Z40 A;  2HGF A;  2Z8V A;  3HMR A;  5COE A;  3SRI A;  1GMO A;  4R1C A;  2YIP A;  3HMS A;  4R19 A;  2Z8W A;  4Z0F A;  1W81 A;  5I25 A;  4YIV A;  2K13 X;  4R1A A;  2F83 A;  5EOK A;  2LL4 M;  4UV6 A;  3HMT A;  4Z0D A;  2Q8A A;  2KL5 A;  2X2Z A;  4IUA A;  5CT2 A;  3SP8 A;  4DUR A;  5CT1 A;  2J8L A;  2QJ2 A;  5EOD A;  1BHT A;  3MKP A;  5CS9 A;  2YIO A;  5CS5 A;  3HN4 A;  1HKY A;  2Y8R A;  5CSQ A;  5CT3 A;  4Z0E A;  4Z09 A;  2QJ4 A;  1GMN A;  1W8K A;  4YIZ A;  1NK1 A;  4A5T S;  2J8J A;  2YIL A;  1GP9 A;  3SRJ A;  4APM A;  5CS3 A;  5CP9 A;  2LL3 A;  2Q8B A;  4APL A; 
#chains in the Genus database with same CATH homology
 1YXE A;  3ZWZ A;  4R1B A;  4UAO A;  5CS1 A;  1I8N A;  3ZLE A;  1Z40 A;  2HGF A;  2Z8V A;  3HMR A;  5COE A;  3SRI A;  1GMO A;  4R1C A;  2YIP A;  3HMS A;  4R19 A;  2Z8W A;  4Z0F A;  1W81 A;  5I25 A;  4YIV A;  2K13 X;  4R1A A;  2F83 A;  5EOK A;  2LL4 M;  4UV6 A;  3HMT A;  4Z0D A;  2Q8A A;  2KL5 A;  2X2Z A;  4IUA A;  5CT2 A;  3SP8 A;  4DUR A;  5CT1 A;  2J8L A;  2QJ2 A;  5EOD A;  1BHT A;  3MKP A;  5CS9 A;  2YIO A;  5CS5 A;  3HN4 A;  1HKY A;  2Y8R A;  5CSQ A;  5CT3 A;  4Z0E A;  4Z09 A;  2QJ4 A;  1GMN A;  1W8K A;  4YIZ A;  1NK1 A;  4A5T S;  2J8J A;  2YIL A;  1GP9 A;  3SRJ A;  4APM A;  5CS3 A;  5CP9 A;  2LL3 A;  2Q8B A;  4APL A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

2Z8VA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN