2Z8W | Genus

Total Genus 84

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	84
sequence length	335
structure length	335
Chain Sequence	NYMGNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLTPVATGNQYLKDGGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCNKDESKRNSMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPKQYEQHLTDYEKIKEGFKNKNASMIKSAFLPTGAFKADRYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Immune system
source organism	Plasmodium falciparum
publication title	Structure of an IgNAR-AMA1 Complex: Targeting a Conserved Hydrophobic Cleft Broadens Malarial Strain Recognition pubmed doi rcsb
molecule keywords	Apical membrane antigen 1
total genus	84
structure length	335
sequence length	335
chains with identical sequence	B
ec nomenclature
pdb deposition date	2007-09-11

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.50.4.10	Alpha Beta	3-Layer(bba) Sandwich	Hepatocyte Growth Factor	Hepatocyte Growth Factor	2z8wA01

2J8LA 4IUAA 2HGFA 1BHTA 3HN4A 4R1AA 4UV6A 5CS1A 4R19A 1Z40A 3HMRA 3ZLEA 5CT2A 3SP8A 1I8NA 2LL3A 1YXEA 4R1BA 5CT3A 3SRIA 2X2ZA 4UAOA 5COEA 5EODA 4Z0FA 2Y8RA 2K13X 4Z0DA 5EOKA 2YILA 3ZWZA 5CS3A 5CT1A 3HMSA 2YIPA 5CSQA 2QJ4A 3MKPA 2LL4M 5CP9A 5CS9A 4Z09A 1W81A 2F83A 3SRJA 4Z0EA 4A5TS 4R1CA 1GP9A 1GMNA 4DURA 5CS5A 2QJ2A 3HMTA 2Z8VA 5I25A 1GMOA 1HKYA 4APLA 1NK1A 4APMA 2Q8BA 2Z8WA 1W8KA 2J8JA 2YIOA 2Q8AA
chains in the Genus database with same CATH superfamily

2J8LA 4IUAA 2HGFA 2KL5A 1BHTA 3HN4A 4R1AA 4UV6A 5CS1A 4R19A 1Z40A 3HMRA 3ZLEA 5CT2A 3SP8A 1I8NA 2LL3A 1YXEA 4R1BA 4YIZA 5CT3A 3SRIA 2X2ZA 4UAOA 5COEA 5EODA 4Z0FA 2Y8RA 2K13X 4Z0DA 5EOKA 2YILA 3ZWZA 5CS3A 5CT1A 3HMSA 2YIPA 4YIVA 5CSQA 2QJ4A 3MKPA 2LL4M 5CP9A 5CS9A 4Z09A 1W81A 2F83A 3SRJA 4Z0EA 4A5TS 4R1CA 1GP9A 1GMNA 4DURA 5CS5A 2QJ2A 3HMTA 2Z8VA 5I25A 1GMOA 1HKYA 4APLA 1NK1A 4APMA 2Q8BA 2Z8WA 1W8KA 2J8JA 2YIOA 2Q8AA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2J8L A;  4IUA A;  2HGF A;  1BHT A;  3HN4 A;  4R1A A;  4UV6 A;  5CS1 A;  4R19 A;  1Z40 A;  3HMR A;  3ZLE A;  5CT2 A;  3SP8 A;  1I8N A;  2LL3 A;  1YXE A;  4R1B A;  5CT3 A;  3SRI A;  2X2Z A;  4UAO A;  5COE A;  5EOD A;  4Z0F A;  2Y8R A;  2K13 X;  4Z0D A;  5EOK A;  2YIL A;  3ZWZ A;  5CS3 A;  5CT1 A;  3HMS A;  2YIP A;  5CSQ A;  2QJ4 A;  3MKP A;  2LL4 M;  5CP9 A;  5CS9 A;  4Z09 A;  1W81 A;  2F83 A;  3SRJ A;  4Z0E A;  4A5T S;  4R1C A;  1GP9 A;  1GMN A;  4DUR A;  5CS5 A;  2QJ2 A;  3HMT A;  2Z8V A;  5I25 A;  1GMO A;  1HKY A;  4APL A;  1NK1 A;  4APM A;  2Q8B A;  2Z8W A;  1W8K A;  2J8J A;  2YIO A;  2Q8A A; 
#chains in the Genus database with same CATH topology
 2J8L A;  4IUA A;  2HGF A;  2KL5 A;  1BHT A;  3HN4 A;  4R1A A;  4UV6 A;  5CS1 A;  4R19 A;  1Z40 A;  3HMR A;  3ZLE A;  5CT2 A;  3SP8 A;  1I8N A;  2LL3 A;  1YXE A;  4R1B A;  4YIZ A;  5CT3 A;  3SRI A;  2X2Z A;  4UAO A;  5COE A;  5EOD A;  4Z0F A;  2Y8R A;  2K13 X;  4Z0D A;  5EOK A;  2YIL A;  3ZWZ A;  5CS3 A;  5CT1 A;  3HMS A;  2YIP A;  4YIV A;  5CSQ A;  2QJ4 A;  3MKP A;  2LL4 M;  5CP9 A;  5CS9 A;  4Z09 A;  1W81 A;  2F83 A;  3SRJ A;  4Z0E A;  4A5T S;  4R1C A;  1GP9 A;  1GMN A;  4DUR A;  5CS5 A;  2QJ2 A;  3HMT A;  2Z8V A;  5I25 A;  1GMO A;  1HKY A;  4APL A;  1NK1 A;  4APM A;  2Q8B A;  2Z8W A;  1W8K A;  2J8J A;  2YIO A;  2Q8A A; 
#chains in the Genus database with same CATH homology
 2J8L A;  4IUA A;  2HGF A;  2KL5 A;  1BHT A;  3HN4 A;  4R1A A;  4UV6 A;  5CS1 A;  4R19 A;  1Z40 A;  3HMR A;  3ZLE A;  5CT2 A;  3SP8 A;  1I8N A;  2LL3 A;  1YXE A;  4R1B A;  4YIZ A;  5CT3 A;  3SRI A;  2X2Z A;  4UAO A;  5COE A;  5EOD A;  4Z0F A;  2Y8R A;  2K13 X;  4Z0D A;  5EOK A;  2YIL A;  3ZWZ A;  5CS3 A;  5CT1 A;  3HMS A;  2YIP A;  4YIV A;  5CSQ A;  2QJ4 A;  3MKP A;  2LL4 M;  5CP9 A;  5CS9 A;  4Z09 A;  1W81 A;  2F83 A;  3SRJ A;  4Z0E A;  4A5T S;  4R1C A;  1GP9 A;  1GMN A;  4DUR A;  5CS5 A;  2QJ2 A;  3HMT A;  2Z8V A;  5I25 A;  1GMO A;  1HKY A;  4APL A;  1NK1 A;  4APM A;  2Q8B A;  2Z8W A;  1W8K A;  2J8J A;  2YIO A;  2Q8A A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2Z8WA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

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