2CSWA

Solution structure of the fha domain of human ubiquitin ligase protein rnf8
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
145
structure length
145
Chain Sequence
GSSGSSGVTGDRAGGRSWCLRRVGMSAGWLLLEDGCEVTVGRGFGVTYQLVSKICPLMISRNHCVLKQNPEGQWTIMDNKSLNGVWLNRARLEPLRVYSIHQGDYIQLGVPLENKENAEYEYEVTEEDWETIYPCLSPKSGPSSG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Solution structure of the FHA domain of human ubiquitin ligase protein RNF8
rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Ubiquitin ligase protein RNF8
total genus 15
structure length 145
sequence length 145
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2005-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 2cswA01
1J4QA 2JKDA 1FHQA 3UMZA 2JQIA 4H87A 3HUFA 2FEZA 3VPYA 2PIEA 3HX1A 3I6UA 1FHRA 3UNMA 1K2NA 3PO8A 3OUNA 1QU5A 3I6WA 2KB4A 2KFUA 2G1LA 2CSWA 4JONA 1J4KA 5E50A 3VA4A 3KT9A 5A8IA 3FM8A 2XT9B 2KB3A 3MDBA 3UNNA 4D9VA 1UJXA 1DMZA 3I0MA 2JPEA 1UHTA 3ELVA 1MZKA 4QCJA 2EH0A 1K3QA 1YJ5C 2JQLA 2LC1A 1WV3A 2W3OA 1K3JA 1LGQA 1J4OA 3POAA 2AFFA 1G3GA 4EGXA 2A0TA 3VA1A 3HUEA 4A0EA 2FF4A 3UOTA 1J4PA 1YJMA 1K3NA 3I0NA 5DJOA 3UV0A 2JQJA 1LGPA 1K2MA 2KKLA 3GQSA 3UN0A 1J4LA 3ELSA 2BRFA 1R21A 1WLNA 4G2SA 1G6GA 4EJQA 1GXCA
chains in the Genus database with same CATH superfamily
1J4QA 1Y3HA 2JKDA 1FHQA 1U7FA 3UMZA 1U0RA 5BVIA 2JQIA 2I1WA 5EJFA 3VZCA 4H87A 5DHTA 3HUFA 4WERA 2I2FA 3DSHA 2FEZA 5JEKA 3VPYA 1G88A 5DHPA 2PIEA 3VZDA 3HX1A 5DHSA 1ZOQA 3GMJA 3I6UA 1Z0UA 1FHRA 5DHQA 3UNMA 1K2NA 3PO8A 5JELA 3OUNA 3DITA 1QU5A 3V8PA 4DY6A 3V7WA 3I6WA 2KB4A 2KFUA 2G1LA 2BONA 2CSWA 4JONA 1J4KA 1MK2A 2QVLA 5E50A 3VA4A 5JERA 5JEOA 2P1RA 1DD1A 3KT9A 3V80A 3V7UA 4JIVD 2AN1A 1U7FB 5A8IA 3FM8A 4KU0D 3T5PA 2XT9B 2KB3A 3PFNA 3MDBA 3UNNA 4D9VA 5JEJA 1UJXA 3V8NA 1YGSA 2I2CA 1DMZA 2JGRA 1MR1A 4HAOA 3I0MA 1Z0SA 2JPEA 5DHRA 1UHTA 1QWTA 5EJGA 3ELVA 3V8QA 4V24A 1MZKA 3S40A 1U7VA 4QCJA 2EH0A 5JEMA 1K3QA 3VZBA 1YJ5C 2JQLA 2I2DA 2LC1A 1WV3A 2W3OA 4L02A 1K3JA 4WRRA 1LGQA 1J4OA 1U0TA 3POAA 2AFFA 1G3GA 4JIWD 3V8MA 5EJHA 4EGXA 1U7VB 4R9PA 3V7YA 2A0TA 3VA1A 3A77A 2Q5FA 3HUEA 4A4YA 4A0EA 2FF4A 3UOTA 5EJIA 1SUWA 3V8RA 1J4PA 1YJMA 1K3NA 3I0NA 3AFOA 1KHUA 5DJOA 3UV0A 1MJSA 5C4VA 2JQJA 1Y3IA 1LGPA 1Z0ZA 1K2MA 2I2BA 2KKLA 2I29A 3GQSA 3UN0A 2QV7A 1J4LA 1KHXA 1YT5A 3ELSA 2BRFA 1R21A 1WLNA 5DHUA 1J2FA 4G2SA 1G6GA 2I2AA 4EJQA 1DEVA 2XXSA 1GXCA
chains in the Genus database with same CATH topology
1J4QA 2JKDA 1FHQA 1U7FA 3UMZA 5BVIA 2JQIA 3VZCA 4H87A 3HUFA 4WERA 3DSHA 2FEZA 5JEKA 3VPYA 1G88A 2PIEA 3VZDA 3HX1A 1ZOQA 3GMJA 3I6UA 1FHRA 3UNMA 1K2NA 3PO8A 5JELA 3OUNA 3DITA 1QU5A 3I6WA 2KB4A 2KFUA 2G1LA 2BONA 2CSWA 4JONA 1J4KA 1MK2A 2QVLA 5E50A 3VA4A 5JERA 5JEOA 2P1RA 1DD1A 3KT9A 4JIVD 1U7FB 5A8IA 3FM8A 4KU0D 3T5PA 2XT9B 2KB3A 3MDBA 3UNNA 4D9VA 5JEJA 1UJXA 1YGSA 1DMZA 2JGRA 1MR1A 3I0MA 2JPEA 1UHTA 1QWTA 3ELVA 4V24A 1MZKA 3S40A 1U7VA 4QCJA 2EH0A 5JEMA 1K3QA 3VZBA 1YJ5C 2JQLA 2LC1A 1WV3A 2W3OA 4L02A 1K3JA 4WRRA 1LGQA 1J4OA 3POAA 2AFFA 1G3GA 4JIWD 4EGXA 1U7VB 4R9PA 2A0TA 3VA1A 3A77A 3HUEA 4A4YA 4A0EA 2FF4A 3UOTA 1J4PA 1YJMA 1K3NA 3I0NA 1KHUA 5DJOA 3UV0A 1MJSA 5C4VA 2JQJA 1LGPA 1K2MA 2KKLA 3GQSA 3UN0A 2QV7A 1J4LA 1KHXA 3ELSA 2BRFA 1R21A 1WLNA 1J2FA 4G2SA 1G6GA 4EJQA 1DEVA 2XXSA 1GXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J4Q A;  2JKD A;  1FHQ A;  3UMZ A;  2JQI A;  4H87 A;  3HUF A;  2FEZ A;  3VPY A;  2PIE A;  3HX1 A;  3I6U A;  1FHR A;  3UNM A;  1K2N A;  3PO8 A;  3OUN A;  1QU5 A;  3I6W A;  2KB4 A;  2KFU A;  2G1L A;  2CSW A;  4JON A;  1J4K A;  5E50 A;  3VA4 A;  3KT9 A;  5A8I A;  3FM8 A;  2XT9 B;  2KB3 A;  3MDB A;  3UNN A;  4D9V A;  1UJX A;  1DMZ A;  3I0M A;  2JPE A;  1UHT A;  3ELV A;  1MZK A;  4QCJ A;  2EH0 A;  1K3Q A;  1YJ5 C;  2JQL A;  2LC1 A;  1WV3 A;  2W3O A;  1K3J A;  1LGQ A;  1J4O A;  3POA A;  2AFF A;  1G3G A;  4EGX A;  2A0T A;  3VA1 A;  3HUE A;  4A0E A;  2FF4 A;  3UOT A;  1J4P A;  1YJM A;  1K3N A;  3I0N A;  5DJO A;  3UV0 A;  2JQJ A;  1LGP A;  1K2M A;  2KKL A;  3GQS A;  3UN0 A;  1J4L A;  3ELS A;  2BRF A;  1R21 A;  1WLN A;  4G2S A;  1G6G A;  4EJQ A;  1GXC A; 
#chains in the Genus database with same CATH topology
 1J4Q A;  1Y3H A;  2JKD A;  1FHQ A;  1U7F A;  3UMZ A;  1U0R A;  5BVI A;  2JQI A;  2I1W A;  5EJF A;  3VZC A;  4H87 A;  5DHT A;  3HUF A;  4WER A;  2I2F A;  3DSH A;  2FEZ A;  5JEK A;  3VPY A;  1G88 A;  5DHP A;  2PIE A;  3VZD A;  3HX1 A;  5DHS A;  1ZOQ A;  3GMJ A;  3I6U A;  1Z0U A;  1FHR A;  5DHQ A;  3UNM A;  1K2N A;  3PO8 A;  5JEL A;  3OUN A;  3DIT A;  1QU5 A;  3V8P A;  4DY6 A;  3V7W A;  3I6W A;  2KB4 A;  2KFU A;  2G1L A;  2BON A;  2CSW A;  4JON A;  1J4K A;  1MK2 A;  2QVL A;  5E50 A;  3VA4 A;  5JER A;  5JEO A;  2P1R A;  1DD1 A;  3KT9 A;  3V80 A;  3V7U A;  4JIV D;  2AN1 A;  1U7F B;  5A8I A;  3FM8 A;  4KU0 D;  3T5P A;  2XT9 B;  2KB3 A;  3PFN A;  3MDB A;  3UNN A;  4D9V A;  5JEJ A;  1UJX A;  3V8N A;  1YGS A;  2I2C A;  1DMZ A;  2JGR A;  1MR1 A;  4HAO A;  3I0M A;  1Z0S A;  2JPE A;  5DHR A;  1UHT A;  1QWT A;  5EJG A;  3ELV A;  3V8Q A;  4V24 A;  1MZK A;  3S40 A;  1U7V A;  4QCJ A;  2EH0 A;  5JEM A;  1K3Q A;  3VZB A;  1YJ5 C;  2JQL A;  2I2D A;  2LC1 A;  1WV3 A;  2W3O A;  4L02 A;  1K3J A;  4WRR A;  1LGQ A;  1J4O A;  1U0T A;  3POA A;  2AFF A;  1G3G A;  4JIW D;  3V8M A;  5EJH A;  4EGX A;  1U7V B;  4R9P A;  3V7Y A;  2A0T A;  3VA1 A;  3A77 A;  2Q5F A;  3HUE A;  4A4Y A;  4A0E A;  2FF4 A;  3UOT A;  5EJI A;  1SUW A;  3V8R A;  1J4P A;  1YJM A;  1K3N A;  3I0N A;  3AFO A;  1KHU A;  5DJO A;  3UV0 A;  1MJS A;  5C4V A;  2JQJ A;  1Y3I A;  1LGP A;  1Z0Z A;  1K2M A;  2I2B A;  2KKL A;  2I29 A;  3GQS A;  3UN0 A;  2QV7 A;  1J4L A;  1KHX A;  1YT5 A;  3ELS A;  2BRF A;  1R21 A;  1WLN A;  5DHU A;  1J2F A;  4G2S A;  1G6G A;  2I2A A;  4EJQ A;  1DEV A;  2XXS A;  1GXC A; 
#chains in the Genus database with same CATH homology
 1J4Q A;  2JKD A;  1FHQ A;  1U7F A;  3UMZ A;  5BVI A;  2JQI A;  3VZC A;  4H87 A;  3HUF A;  4WER A;  3DSH A;  2FEZ A;  5JEK A;  3VPY A;  1G88 A;  2PIE A;  3VZD A;  3HX1 A;  1ZOQ A;  3GMJ A;  3I6U A;  1FHR A;  3UNM A;  1K2N A;  3PO8 A;  5JEL A;  3OUN A;  3DIT A;  1QU5 A;  3I6W A;  2KB4 A;  2KFU A;  2G1L A;  2BON A;  2CSW A;  4JON A;  1J4K A;  1MK2 A;  2QVL A;  5E50 A;  3VA4 A;  5JER A;  5JEO A;  2P1R A;  1DD1 A;  3KT9 A;  4JIV D;  1U7F B;  5A8I A;  3FM8 A;  4KU0 D;  3T5P A;  2XT9 B;  2KB3 A;  3MDB A;  3UNN A;  4D9V A;  5JEJ A;  1UJX A;  1YGS A;  1DMZ A;  2JGR A;  1MR1 A;  3I0M A;  2JPE A;  1UHT A;  1QWT A;  3ELV A;  4V24 A;  1MZK A;  3S40 A;  1U7V A;  4QCJ A;  2EH0 A;  5JEM A;  1K3Q A;  3VZB A;  1YJ5 C;  2JQL A;  2LC1 A;  1WV3 A;  2W3O A;  4L02 A;  1K3J A;  4WRR A;  1LGQ A;  1J4O A;  3POA A;  2AFF A;  1G3G A;  4JIW D;  4EGX A;  1U7V B;  4R9P A;  2A0T A;  3VA1 A;  3A77 A;  3HUE A;  4A4Y A;  4A0E A;  2FF4 A;  3UOT A;  1J4P A;  1YJM A;  1K3N A;  3I0N A;  1KHU A;  5DJO A;  3UV0 A;  1MJS A;  5C4V A;  2JQJ A;  1LGP A;  1K2M A;  2KKL A;  3GQS A;  3UN0 A;  2QV7 A;  1J4L A;  1KHX A;  3ELS A;  2BRF A;  1R21 A;  1WLN A;  1J2F A;  4G2S A;  1G6G A;  4EJQ A;  1DEV A;  2XXS A;  1GXC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...