3FM8A

Crystal structure of full length centaurin alpha-1 bound with the fha domain of kif13b (capri target)
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
98
structure length
98
Chain Sequence
CFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCIIDITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRLNLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transport protein/hydrolase activator
source organism Homo sapiens
publication title Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.
pubmed doi rcsb
molecule keywords Kinesin-like protein KIF13B
total genus 21
structure length 98
sequence length 98
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-12-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 3fm8A00
1LGQA 2JPEA 4JONA 1MZKA 3I0NA 3I6WA 2JQJA 2KFUA 3UOTA 2JQIA 1K2MA 1FHQA 2JQLA 1R21A 1UJXA 1UHTA 5A8IA 3UNNA 1FHRA 1J4LA 3HX1A 4EJQA 2A0TA 3VA1A 3VPYA 2PIEA 3POAA 1J4PA 3GQSA 1J4KA 4QCJA 3VA4A 2FEZA 2KKLA 4A0EA 2AFFA 3MDBA 3FM8A 3HUFA 2XT9B 1DMZA 1LGPA 4H87A 2G1LA 5E50A 1K2NA 2FF4A 3I0MA 2BRFA 1YJMA 3ELVA 1QU5A 1WLNA 1J4OA 1K3JA 1WV3A 2EH0A 3PO8A 3UN0A 2LC1A 4G2SA 2KB4A 1YJ5C 1G3GA 2JKDA 2KB3A 3ELSA 1J4QA 3OUNA 3I6UA 1GXCA 1K3NA 3UNMA 3UV0A 1G6GA 4EGXA 5DJOA 4D9VA 1K3QA 3HUEA 2CSWA 2W3OA 3KT9A 3UMZA
chains in the Genus database with same CATH superfamily
4R9PA 2I1WA 1LGQA 2JPEA 3DITA 1QWTA 4JONA 1MZKA 3I0NA 4JIWD 3I6WA 2I29A 1U0TA 5BVIA 2JQJA 2KFUA 3V8QA 4A4YA 1Z0SA 3V8NA 3UOTA 5EJGA 2JQIA 3V7YA 3S40A 5DHUA 2JGRA 1K2MA 1FHQA 3V7UA 2JQLA 2I2FA 1YT5A 1ZOQA 1R21A 3GMJA 1UJXA 1MJSA 5EJIA 1UHTA 1DEVA 5A8IA 5JEMA 5JELA 5DHPA 2I2DA 3VZCA 3UNNA 5JEJA 1YGSA 1DD1A 1FHRA 1U7VA 2I2BA 4JIVD 1J4LA 3V8MA 4DY6A 3HX1A 2QVLA 1U7FA 5EJFA 4EJQA 2A0TA 1Z0UA 3VA1A 2I2CA 5EJHA 3VPYA 1Z0ZA 1G88A 2PIEA 5DHRA 3V8RA 3POAA 1J4PA 3GQSA 1J4KA 4QCJA 1U7VB 1SUWA 3VA4A 3V8PA 4WERA 2Q5FA 1MK2A 2FEZA 2KKLA 4A0EA 2AFFA 3MDBA 3FM8A 3VZBA 3HUFA 2XT9B 3V80A 2XXSA 1DMZA 5DHQA 1LGPA 4H87A 3T5PA 1J2FA 2G1LA 5E50A 1K2NA 2FF4A 3I0MA 2BRFA 1Y3HA 1YJMA 3ELVA 1QU5A 2QV7A 3A77A 1WLNA 5C4VA 1U0RA 1J4OA 4KU0D 4V24A 1K3JA 5DHTA 1WV3A 2EH0A 3PO8A 1KHUA 2I2AA 5JEOA 3UN0A 1U7FB 2LC1A 3VZDA 4G2SA 2AN1A 2KB4A 4WRRA 1YJ5C 1G3GA 3AFOA 2JKDA 4HAOA 2KB3A 3ELSA 1J4QA 1Y3IA 3OUNA 1MR1A 1KHXA 3I6UA 1GXCA 3V7WA 5JERA 1K3NA 3UNMA 3UV0A 1G6GA 4EGXA 4L02A 5DJOA 4D9VA 1K3QA 2P1RA 3DSHA 3HUEA 2CSWA 2BONA 2W3OA 3KT9A 5JEKA 3UMZA 3PFNA 5DHSA
chains in the Genus database with same CATH topology
4R9PA 1LGQA 2JPEA 3DITA 1QWTA 4JONA 1MZKA 3I0NA 4JIWD 3I6WA 5BVIA 2JQJA 2KFUA 4A4YA 3UOTA 2JQIA 3S40A 2JGRA 1K2MA 1FHQA 2JQLA 3GMJA 1ZOQA 1R21A 1UJXA 1MJSA 1UHTA 1DEVA 5A8IA 5JEMA 5JELA 3VZCA 3UNNA 5JEJA 1YGSA 1DD1A 1FHRA 1U7VA 4JIVD 1J4LA 3HX1A 2QVLA 1U7FA 4EJQA 2A0TA 3VA1A 3VPYA 1G88A 2PIEA 3POAA 1J4PA 3GQSA 1J4KA 4QCJA 1U7VB 3VA4A 4WERA 1MK2A 2FEZA 2KKLA 4A0EA 2AFFA 3MDBA 3FM8A 3VZBA 3HUFA 2XT9B 2XXSA 1DMZA 1LGPA 4H87A 3T5PA 1J2FA 2G1LA 5E50A 1K2NA 2FF4A 3I0MA 2BRFA 1YJMA 3ELVA 1QU5A 2QV7A 3A77A 1WLNA 5C4VA 4V24A 1J4OA 4KU0D 1K3JA 1WV3A 2EH0A 3PO8A 1KHUA 5JEOA 3UN0A 1U7FB 2LC1A 3VZDA 4G2SA 2KB4A 4WRRA 1YJ5C 1G3GA 2JKDA 2KB3A 3ELSA 1J4QA 3OUNA 1MR1A 1KHXA 3I6UA 1GXCA 5JERA 1K3NA 3UNMA 3UV0A 1G6GA 4EGXA 4L02A 5DJOA 4D9VA 1K3QA 2P1RA 3DSHA 3HUEA 2CSWA 2BONA 2W3OA 3KT9A 5JEKA 3UMZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1LGQ A;  2JPE A;  4JON A;  1MZK A;  3I0N A;  3I6W A;  2JQJ A;  2KFU A;  3UOT A;  2JQI A;  1K2M A;  1FHQ A;  2JQL A;  1R21 A;  1UJX A;  1UHT A;  5A8I A;  3UNN A;  1FHR A;  1J4L A;  3HX1 A;  4EJQ A;  2A0T A;  3VA1 A;  3VPY A;  2PIE A;  3POA A;  1J4P A;  3GQS A;  1J4K A;  4QCJ A;  3VA4 A;  2FEZ A;  2KKL A;  4A0E A;  2AFF A;  3MDB A;  3FM8 A;  3HUF A;  2XT9 B;  1DMZ A;  1LGP A;  4H87 A;  2G1L A;  5E50 A;  1K2N A;  2FF4 A;  3I0M A;  2BRF A;  1YJM A;  3ELV A;  1QU5 A;  1WLN A;  1J4O A;  1K3J A;  1WV3 A;  2EH0 A;  3PO8 A;  3UN0 A;  2LC1 A;  4G2S A;  2KB4 A;  1YJ5 C;  1G3G A;  2JKD A;  2KB3 A;  3ELS A;  1J4Q A;  3OUN A;  3I6U A;  1GXC A;  1K3N A;  3UNM A;  3UV0 A;  1G6G A;  4EGX A;  5DJO A;  4D9V A;  1K3Q A;  3HUE A;  2CSW A;  2W3O A;  3KT9 A;  3UMZ A; 
#chains in the Genus database with same CATH topology
 4R9P A;  2I1W A;  1LGQ A;  2JPE A;  3DIT A;  1QWT A;  4JON A;  1MZK A;  3I0N A;  4JIW D;  3I6W A;  2I29 A;  1U0T A;  5BVI A;  2JQJ A;  2KFU A;  3V8Q A;  4A4Y A;  1Z0S A;  3V8N A;  3UOT A;  5EJG A;  2JQI A;  3V7Y A;  3S40 A;  5DHU A;  2JGR A;  1K2M A;  1FHQ A;  3V7U A;  2JQL A;  2I2F A;  1YT5 A;  1ZOQ A;  1R21 A;  3GMJ A;  1UJX A;  1MJS A;  5EJI A;  1UHT A;  1DEV A;  5A8I A;  5JEM A;  5JEL A;  5DHP A;  2I2D A;  3VZC A;  3UNN A;  5JEJ A;  1YGS A;  1DD1 A;  1FHR A;  1U7V A;  2I2B A;  4JIV D;  1J4L A;  3V8M A;  4DY6 A;  3HX1 A;  2QVL A;  1U7F A;  5EJF A;  4EJQ A;  2A0T A;  1Z0U A;  3VA1 A;  2I2C A;  5EJH A;  3VPY A;  1Z0Z A;  1G88 A;  2PIE A;  5DHR A;  3V8R A;  3POA A;  1J4P A;  3GQS A;  1J4K A;  4QCJ A;  1U7V B;  1SUW A;  3VA4 A;  3V8P A;  4WER A;  2Q5F A;  1MK2 A;  2FEZ A;  2KKL A;  4A0E A;  2AFF A;  3MDB A;  3FM8 A;  3VZB A;  3HUF A;  2XT9 B;  3V80 A;  2XXS A;  1DMZ A;  5DHQ A;  1LGP A;  4H87 A;  3T5P A;  1J2F A;  2G1L A;  5E50 A;  1K2N A;  2FF4 A;  3I0M A;  2BRF A;  1Y3H A;  1YJM A;  3ELV A;  1QU5 A;  2QV7 A;  3A77 A;  1WLN A;  5C4V A;  1U0R A;  1J4O A;  4KU0 D;  4V24 A;  1K3J A;  5DHT A;  1WV3 A;  2EH0 A;  3PO8 A;  1KHU A;  2I2A A;  5JEO A;  3UN0 A;  1U7F B;  2LC1 A;  3VZD A;  4G2S A;  2AN1 A;  2KB4 A;  4WRR A;  1YJ5 C;  1G3G A;  3AFO A;  2JKD A;  4HAO A;  2KB3 A;  3ELS A;  1J4Q A;  1Y3I A;  3OUN A;  1MR1 A;  1KHX A;  3I6U A;  1GXC A;  3V7W A;  5JER A;  1K3N A;  3UNM A;  3UV0 A;  1G6G A;  4EGX A;  4L02 A;  5DJO A;  4D9V A;  1K3Q A;  2P1R A;  3DSH A;  3HUE A;  2CSW A;  2BON A;  2W3O A;  3KT9 A;  5JEK A;  3UMZ A;  3PFN A;  5DHS A; 
#chains in the Genus database with same CATH homology
 4R9P A;  1LGQ A;  2JPE A;  3DIT A;  1QWT A;  4JON A;  1MZK A;  3I0N A;  4JIW D;  3I6W A;  5BVI A;  2JQJ A;  2KFU A;  4A4Y A;  3UOT A;  2JQI A;  3S40 A;  2JGR A;  1K2M A;  1FHQ A;  2JQL A;  3GMJ A;  1ZOQ A;  1R21 A;  1UJX A;  1MJS A;  1UHT A;  1DEV A;  5A8I A;  5JEM A;  5JEL A;  3VZC A;  3UNN A;  5JEJ A;  1YGS A;  1DD1 A;  1FHR A;  1U7V A;  4JIV D;  1J4L A;  3HX1 A;  2QVL A;  1U7F A;  4EJQ A;  2A0T A;  3VA1 A;  3VPY A;  1G88 A;  2PIE A;  3POA A;  1J4P A;  3GQS A;  1J4K A;  4QCJ A;  1U7V B;  3VA4 A;  4WER A;  1MK2 A;  2FEZ A;  2KKL A;  4A0E A;  2AFF A;  3MDB A;  3FM8 A;  3VZB A;  3HUF A;  2XT9 B;  2XXS A;  1DMZ A;  1LGP A;  4H87 A;  3T5P A;  1J2F A;  2G1L A;  5E50 A;  1K2N A;  2FF4 A;  3I0M A;  2BRF A;  1YJM A;  3ELV A;  1QU5 A;  2QV7 A;  3A77 A;  1WLN A;  5C4V A;  4V24 A;  1J4O A;  4KU0 D;  1K3J A;  1WV3 A;  2EH0 A;  3PO8 A;  1KHU A;  5JEO A;  3UN0 A;  1U7F B;  2LC1 A;  3VZD A;  4G2S A;  2KB4 A;  4WRR A;  1YJ5 C;  1G3G A;  2JKD A;  2KB3 A;  3ELS A;  1J4Q A;  3OUN A;  1MR1 A;  1KHX A;  3I6U A;  1GXC A;  5JER A;  1K3N A;  3UNM A;  3UV0 A;  1G6G A;  4EGX A;  4L02 A;  5DJO A;  4D9V A;  1K3Q A;  2P1R A;  3DSH A;  3HUE A;  2CSW A;  2BON A;  2W3O A;  3KT9 A;  5JEK A;  3UMZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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