3HMRA

Crystal structure of the n-terminal fragment (31-127) of the mouse hepatocyte growth factor/scatter factor
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
90
structure length
90
Chain Sequence
NTLHEFKKSAKTTLTKEDPLLKIKTKKVNSADECANRCIRNRGFTFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLYENKDYIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hormone
source organism Mus musculus
publication title Structural basis for agonism and antagonism of hepatocyte growth factor.
pubmed doi rcsb
molecule keywords Hepatocyte growth factor
total genus 23
structure length 90
sequence length 90
ec nomenclature
pdb deposition date 2009-05-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00024 PAN_1 PAN domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 3hmrA00
3SRIA 4APLA 4IUAA 5COEA 4UV6A 5CS3A 1HKYA 4Z0EA 2Z8WA 4R1AA 4UAOA 4Z0FA 2LL3A 5CSQA 4Z0DA 5EODA 2K13X 5CT2A 2Z8VA 5I25A 4APMA 3ZWZA 1GMOA 5CT1A 1W8KA 2J8JA 5CP9A 3HMTA 2Q8AA 5CS5A 4A5TS 4Z09A 2QJ4A 2F83A 4R1CA 1YXEA 2LL4M 2YIPA 1BHTA 1Z40A 2YILA 3HMSA 2QJ2A 3HN4A 3MKPA 5CT3A 3SRJA 4DURA 2YIOA 2HGFA 2X2ZA 2Y8RA 3SP8A 3ZLEA 1NK1A 1W81A 5CS1A 2Q8BA 1GP9A 1I8NA 1GMNA 5EOKA 2J8LA 4R19A 5CS9A 4R1BA 3HMRA
chains in the Genus database with same CATH superfamily
3SRIA 4APLA 4IUAA 4YIZA 5COEA 4UV6A 5CS3A 1HKYA 4Z0EA 2Z8WA 4R1AA 4UAOA 4Z0FA 2LL3A 5CSQA 4Z0DA 5EODA 2K13X 5CT2A 2Z8VA 5I25A 4APMA 3ZWZA 1GMOA 5CT1A 1W8KA 2J8JA 5CP9A 3HMTA 2Q8AA 5CS5A 4A5TS 4Z09A 2QJ4A 2F83A 2KL5A 4R1CA 1YXEA 2LL4M 2YIPA 1BHTA 1Z40A 2YILA 3HMSA 2QJ2A 3HN4A 3MKPA 5CT3A 3SRJA 4DURA 2YIOA 2HGFA 2X2ZA 2Y8RA 3SP8A 3ZLEA 1NK1A 1W81A 5CS1A 2Q8BA 1GP9A 1I8NA 1GMNA 5EOKA 4YIVA 2J8LA 4R19A 5CS9A 4R1BA 3HMRA
chains in the Genus database with same CATH topology
3SRIA 4APLA 4IUAA 4YIZA 5COEA 4UV6A 5CS3A 1HKYA 4Z0EA 2Z8WA 4R1AA 4UAOA 4Z0FA 2LL3A 5CSQA 4Z0DA 5EODA 2K13X 5CT2A 2Z8VA 5I25A 4APMA 3ZWZA 1GMOA 5CT1A 1W8KA 2J8JA 5CP9A 3HMTA 2Q8AA 5CS5A 4A5TS 4Z09A 2QJ4A 2F83A 2KL5A 4R1CA 1YXEA 2LL4M 2YIPA 1BHTA 1Z40A 2YILA 3HMSA 2QJ2A 3HN4A 3MKPA 5CT3A 3SRJA 4DURA 2YIOA 2HGFA 2X2ZA 2Y8RA 3SP8A 3ZLEA 1NK1A 1W81A 5CS1A 2Q8BA 1GP9A 1I8NA 1GMNA 5EOKA 4YIVA 2J8LA 4R19A 5CS9A 4R1BA 3HMRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SRI A;  4APL A;  4IUA A;  5COE A;  4UV6 A;  5CS3 A;  1HKY A;  4Z0E A;  2Z8W A;  4R1A A;  4UAO A;  4Z0F A;  2LL3 A;  5CSQ A;  4Z0D A;  5EOD A;  2K13 X;  5CT2 A;  2Z8V A;  5I25 A;  4APM A;  3ZWZ A;  1GMO A;  5CT1 A;  1W8K A;  2J8J A;  5CP9 A;  3HMT A;  2Q8A A;  5CS5 A;  4A5T S;  4Z09 A;  2QJ4 A;  2F83 A;  4R1C A;  1YXE A;  2LL4 M;  2YIP A;  1BHT A;  1Z40 A;  2YIL A;  3HMS A;  2QJ2 A;  3HN4 A;  3MKP A;  5CT3 A;  3SRJ A;  4DUR A;  2YIO A;  2HGF A;  2X2Z A;  2Y8R A;  3SP8 A;  3ZLE A;  1NK1 A;  1W81 A;  5CS1 A;  2Q8B A;  1GP9 A;  1I8N A;  1GMN A;  5EOK A;  2J8L A;  4R19 A;  5CS9 A;  4R1B A;  3HMR A; 
#chains in the Genus database with same CATH topology
 3SRI A;  4APL A;  4IUA A;  4YIZ A;  5COE A;  4UV6 A;  5CS3 A;  1HKY A;  4Z0E A;  2Z8W A;  4R1A A;  4UAO A;  4Z0F A;  2LL3 A;  5CSQ A;  4Z0D A;  5EOD A;  2K13 X;  5CT2 A;  2Z8V A;  5I25 A;  4APM A;  3ZWZ A;  1GMO A;  5CT1 A;  1W8K A;  2J8J A;  5CP9 A;  3HMT A;  2Q8A A;  5CS5 A;  4A5T S;  4Z09 A;  2QJ4 A;  2F83 A;  2KL5 A;  4R1C A;  1YXE A;  2LL4 M;  2YIP A;  1BHT A;  1Z40 A;  2YIL A;  3HMS A;  2QJ2 A;  3HN4 A;  3MKP A;  5CT3 A;  3SRJ A;  4DUR A;  2YIO A;  2HGF A;  2X2Z A;  2Y8R A;  3SP8 A;  3ZLE A;  1NK1 A;  1W81 A;  5CS1 A;  2Q8B A;  1GP9 A;  1I8N A;  1GMN A;  5EOK A;  4YIV A;  2J8L A;  4R19 A;  5CS9 A;  4R1B A;  3HMR A; 
#chains in the Genus database with same CATH homology
 3SRI A;  4APL A;  4IUA A;  4YIZ A;  5COE A;  4UV6 A;  5CS3 A;  1HKY A;  4Z0E A;  2Z8W A;  4R1A A;  4UAO A;  4Z0F A;  2LL3 A;  5CSQ A;  4Z0D A;  5EOD A;  2K13 X;  5CT2 A;  2Z8V A;  5I25 A;  4APM A;  3ZWZ A;  1GMO A;  5CT1 A;  1W8K A;  2J8J A;  5CP9 A;  3HMT A;  2Q8A A;  5CS5 A;  4A5T S;  4Z09 A;  2QJ4 A;  2F83 A;  2KL5 A;  4R1C A;  1YXE A;  2LL4 M;  2YIP A;  1BHT A;  1Z40 A;  2YIL A;  3HMS A;  2QJ2 A;  3HN4 A;  3MKP A;  5CT3 A;  3SRJ A;  4DUR A;  2YIO A;  2HGF A;  2X2Z A;  2Y8R A;  3SP8 A;  3ZLE A;  1NK1 A;  1W81 A;  5CS1 A;  2Q8B A;  1GP9 A;  1I8N A;  1GMN A;  5EOK A;  4YIV A;  2J8L A;  4R19 A;  5CS9 A;  4R1B A;  3HMR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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