3UV0A

Crystal structure of the drosophila mu2 fha domain
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
97
structure length
97
Chain Sequence
DVSLFFGGLPAILLKADTIYRIGRQKGLEISIADESMELAHATACILRRGVVRLAALVGKIFVNDQEETVVDIGMENAVAGKVKLRFGNVEARLEFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1
pubmed doi rcsb
molecule tags Protein binding
source organism Drosophila melanogaster
molecule keywords Mutator 2, isoform B
total genus 19
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18221 MU2_FHA Mutator 2 Fork head associated domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 3uv0A00
1J4OA 4A0EA 2JQIA 1K3JA 3OUNA 2EH0A 1LGQA 3I0NA 3HUFA 1K3QA 2G1LA 3VPYA 3UNNA 5E50A 2KKLA 2JQJA 2PIEA 3I6WA 1MZKA 1QU5A 4H87A 2FF4A 4EGXA 2JKDA 3HX1A 1YJMA 2FEZA 1FHQA 2JQLA 2JPEA 1DMZA 5DJOA 3ELVA 4QCJA 3I0MA 1WV3A 2KB4A 3UNMA 1LGPA 3UOTA 4JONA 3GQSA 1K2MA 1K3NA 3I6UA 1J4PA 3FM8A 5A8IA 3ELSA 2W3OA 3UMZA 1FHRA 1WLNA 3PO8A 3VA4A 2CSWA 1J4LA 4G2SA 3POAA 1G3GA 1K2NA 3UN0A 1J4KA 1G6GA 3HUEA 1R21A 2AFFA 3VA1A 3MDBA 1J4QA 2XT9B 2KFUA 2A0TA 1UHTA 4EJQA 2KB3A 3KT9A 3UV0A 1YJ5C 2BRFA 1GXCA 2LC1A 4D9VA 1UJXA
chains in the Genus database with same CATH superfamily
1U7VB 1J4OA 3AFOA 2JQIA 4A0EA 5JELA 1K3JA 3OUNA 2EH0A 5JERA 1LGQA 3I0NA 5BVIA 3HUFA 1K3QA 2G1LA 3S40A 1SUWA 2I2DA 3V80A 3V8MA 5JEKA 5DHSA 2I29A 3VPYA 3UNNA 5E50A 5DHTA 2KKLA 5DHQA 4KU0D 3V8RA 5JEOA 2JQJA 2PIEA 2QVLA 1DEVA 3I6WA 1Z0ZA 1MZKA 4WRRA 1KHXA 5JEMA 1QU5A 2XXSA 3A77A 4H87A 3V7WA 2FF4A 4EGXA 2I1WA 2JKDA 3HX1A 4JIVD 3T5PA 1MR1A 1YJMA 2FEZA 1FHQA 1DD1A 2I2FA 5DHUA 5EJFA 2I2BA 1Y3HA 1U0TA 2JQLA 2JPEA 1DMZA 4DY6A 5DJOA 1QWTA 3GMJA 3VZBA 3ELVA 4QCJA 3I0MA 3V7YA 1WV3A 2KB4A 3UNMA 1LGPA 3UOTA 2I2AA 4V24A 4JONA 4WERA 1KHUA 4HAOA 3GQSA 1K2MA 1K3NA 3I6UA 1MK2A 3V8PA 1J4PA 1MJSA 4R9PA 1U7FA 3VZCA 3FM8A 5A8IA 2JGRA 4JIWD 3ELSA 4L02A 5JEJA 1G88A 1U7FB 2W3OA 3UMZA 1FHRA 1ZOQA 1WLNA 3PO8A 5EJHA 3VA4A 2CSWA 1Z0SA 1J4LA 4G2SA 3POAA 5DHPA 2AN1A 3PFNA 1G3GA 1K2NA 5C4VA 3UN0A 1J4KA 1G6GA 2Q5FA 3DITA 3VZDA 3HUEA 1R21A 2AFFA 1Y3IA 1YGSA 3VA1A 3V7UA 3DSHA 3MDBA 1U0RA 1J4QA 4A4YA 5DHRA 1YT5A 2QV7A 2XT9B 2KFUA 2A0TA 1UHTA 4EJQA 3V8NA 2KB3A 3KT9A 1Z0UA 5EJGA 1J2FA 3UV0A 1YJ5C 5EJIA 2BRFA 1U7VA 1GXCA 2LC1A 4D9VA 2BONA 3V8QA 2I2CA 1UJXA 2P1RA
chains in the Genus database with same CATH topology
1U7VB 1J4OA 4A0EA 2JQIA 5JELA 1K3JA 3OUNA 2EH0A 5JERA 1LGQA 3I0NA 5BVIA 3HUFA 1K3QA 2G1LA 3S40A 5JEKA 3VPYA 3UNNA 5E50A 2KKLA 4KU0D 5JEOA 2JQJA 2PIEA 2QVLA 1DEVA 3I6WA 1MZKA 4WRRA 1KHXA 5JEMA 1QU5A 2XXSA 3A77A 4H87A 2FF4A 4EGXA 2JKDA 3HX1A 4JIVD 3T5PA 1MR1A 1YJMA 2FEZA 1FHQA 1DD1A 2JQLA 2JPEA 1DMZA 5DJOA 1QWTA 3GMJA 3VZBA 3ELVA 4QCJA 3I0MA 1WV3A 2KB4A 3UNMA 1LGPA 3UOTA 4V24A 4JONA 4WERA 1KHUA 3GQSA 1K2MA 1K3NA 3I6UA 1MK2A 1J4PA 1MJSA 4R9PA 1U7FA 3VZCA 3FM8A 5A8IA 2JGRA 4JIWD 3ELSA 4L02A 5JEJA 1G88A 1U7FB 2W3OA 3UMZA 1FHRA 1ZOQA 1WLNA 3PO8A 3VA4A 2CSWA 1J4LA 4G2SA 3POAA 1G3GA 1K2NA 5C4VA 3UN0A 1J4KA 1G6GA 3DITA 3VZDA 3HUEA 1R21A 2AFFA 1YGSA 3VA1A 3DSHA 3MDBA 1J4QA 4A4YA 2QV7A 2XT9B 2KFUA 2A0TA 1UHTA 4EJQA 2KB3A 3KT9A 1J2FA 3UV0A 1YJ5C 2BRFA 1U7VA 1GXCA 2LC1A 4D9VA 2BONA 1UJXA 2P1RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1J4O A;  4A0E A;  2JQI A;  1K3J A;  3OUN A;  2EH0 A;  1LGQ A;  3I0N A;  3HUF A;  1K3Q A;  2G1L A;  3VPY A;  3UNN A;  5E50 A;  2KKL A;  2JQJ A;  2PIE A;  3I6W A;  1MZK A;  1QU5 A;  4H87 A;  2FF4 A;  4EGX A;  2JKD A;  3HX1 A;  1YJM A;  2FEZ A;  1FHQ A;  2JQL A;  2JPE A;  1DMZ A;  5DJO A;  3ELV A;  4QCJ A;  3I0M A;  1WV3 A;  2KB4 A;  3UNM A;  1LGP A;  3UOT A;  4JON A;  3GQS A;  1K2M A;  1K3N A;  3I6U A;  1J4P A;  3FM8 A;  5A8I A;  3ELS A;  2W3O A;  3UMZ A;  1FHR A;  1WLN A;  3PO8 A;  3VA4 A;  2CSW A;  1J4L A;  4G2S A;  3POA A;  1G3G A;  1K2N A;  3UN0 A;  1J4K A;  1G6G A;  3HUE A;  1R21 A;  2AFF A;  3VA1 A;  3MDB A;  1J4Q A;  2XT9 B;  2KFU A;  2A0T A;  1UHT A;  4EJQ A;  2KB3 A;  3KT9 A;  3UV0 A;  1YJ5 C;  2BRF A;  1GXC A;  2LC1 A;  4D9V A;  1UJX A; 
#chains in the Genus database with same CATH topology
 1U7V B;  1J4O A;  3AFO A;  2JQI A;  4A0E A;  5JEL A;  1K3J A;  3OUN A;  2EH0 A;  5JER A;  1LGQ A;  3I0N A;  5BVI A;  3HUF A;  1K3Q A;  2G1L A;  3S40 A;  1SUW A;  2I2D A;  3V80 A;  3V8M A;  5JEK A;  5DHS A;  2I29 A;  3VPY A;  3UNN A;  5E50 A;  5DHT A;  2KKL A;  5DHQ A;  4KU0 D;  3V8R A;  5JEO A;  2JQJ A;  2PIE A;  2QVL A;  1DEV A;  3I6W A;  1Z0Z A;  1MZK A;  4WRR A;  1KHX A;  5JEM A;  1QU5 A;  2XXS A;  3A77 A;  4H87 A;  3V7W A;  2FF4 A;  4EGX A;  2I1W A;  2JKD A;  3HX1 A;  4JIV D;  3T5P A;  1MR1 A;  1YJM A;  2FEZ A;  1FHQ A;  1DD1 A;  2I2F A;  5DHU A;  5EJF A;  2I2B A;  1Y3H A;  1U0T A;  2JQL A;  2JPE A;  1DMZ A;  4DY6 A;  5DJO A;  1QWT A;  3GMJ A;  3VZB A;  3ELV A;  4QCJ A;  3I0M A;  3V7Y A;  1WV3 A;  2KB4 A;  3UNM A;  1LGP A;  3UOT A;  2I2A A;  4V24 A;  4JON A;  4WER A;  1KHU A;  4HAO A;  3GQS A;  1K2M A;  1K3N A;  3I6U A;  1MK2 A;  3V8P A;  1J4P A;  1MJS A;  4R9P A;  1U7F A;  3VZC A;  3FM8 A;  5A8I A;  2JGR A;  4JIW D;  3ELS A;  4L02 A;  5JEJ A;  1G88 A;  1U7F B;  2W3O A;  3UMZ A;  1FHR A;  1ZOQ A;  1WLN A;  3PO8 A;  5EJH A;  3VA4 A;  2CSW A;  1Z0S A;  1J4L A;  4G2S A;  3POA A;  5DHP A;  2AN1 A;  3PFN A;  1G3G A;  1K2N A;  5C4V A;  3UN0 A;  1J4K A;  1G6G A;  2Q5F A;  3DIT A;  3VZD A;  3HUE A;  1R21 A;  2AFF A;  1Y3I A;  1YGS A;  3VA1 A;  3V7U A;  3DSH A;  3MDB A;  1U0R A;  1J4Q A;  4A4Y A;  5DHR A;  1YT5 A;  2QV7 A;  2XT9 B;  2KFU A;  2A0T A;  1UHT A;  4EJQ A;  3V8N A;  2KB3 A;  3KT9 A;  1Z0U A;  5EJG A;  1J2F A;  3UV0 A;  1YJ5 C;  5EJI A;  2BRF A;  1U7V A;  1GXC A;  2LC1 A;  4D9V A;  2BON A;  3V8Q A;  2I2C A;  1UJX A;  2P1R A; 
#chains in the Genus database with same CATH homology
 1U7V B;  1J4O A;  4A0E A;  2JQI A;  5JEL A;  1K3J A;  3OUN A;  2EH0 A;  5JER A;  1LGQ A;  3I0N A;  5BVI A;  3HUF A;  1K3Q A;  2G1L A;  3S40 A;  5JEK A;  3VPY A;  3UNN A;  5E50 A;  2KKL A;  4KU0 D;  5JEO A;  2JQJ A;  2PIE A;  2QVL A;  1DEV A;  3I6W A;  1MZK A;  4WRR A;  1KHX A;  5JEM A;  1QU5 A;  2XXS A;  3A77 A;  4H87 A;  2FF4 A;  4EGX A;  2JKD A;  3HX1 A;  4JIV D;  3T5P A;  1MR1 A;  1YJM A;  2FEZ A;  1FHQ A;  1DD1 A;  2JQL A;  2JPE A;  1DMZ A;  5DJO A;  1QWT A;  3GMJ A;  3VZB A;  3ELV A;  4QCJ A;  3I0M A;  1WV3 A;  2KB4 A;  3UNM A;  1LGP A;  3UOT A;  4V24 A;  4JON A;  4WER A;  1KHU A;  3GQS A;  1K2M A;  1K3N A;  3I6U A;  1MK2 A;  1J4P A;  1MJS A;  4R9P A;  1U7F A;  3VZC A;  3FM8 A;  5A8I A;  2JGR A;  4JIW D;  3ELS A;  4L02 A;  5JEJ A;  1G88 A;  1U7F B;  2W3O A;  3UMZ A;  1FHR A;  1ZOQ A;  1WLN A;  3PO8 A;  3VA4 A;  2CSW A;  1J4L A;  4G2S A;  3POA A;  1G3G A;  1K2N A;  5C4V A;  3UN0 A;  1J4K A;  1G6G A;  3DIT A;  3VZD A;  3HUE A;  1R21 A;  2AFF A;  1YGS A;  3VA1 A;  3DSH A;  3MDB A;  1J4Q A;  4A4Y A;  2QV7 A;  2XT9 B;  2KFU A;  2A0T A;  1UHT A;  4EJQ A;  2KB3 A;  3KT9 A;  1J2F A;  3UV0 A;  1YJ5 C;  2BRF A;  1U7V A;  1GXC A;  2LC1 A;  4D9V A;  2BON A;  1UJX A;  2P1R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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