3UNNA

Monomeric structure of the human mdc1 fha domain in complex with an mdc1 phospho-t4 peptide
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
108
structure length
108
Chain Sequence
SNVEPVGRLHIFSGAHGPEKDFPLHLGKNVVGRMPDCSVALPFPSISKQHAEIEILAWDKAPILRDCGSLNGTQILRPPKVLSPGVSHRLRDQELILFADLLCQYHRL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Mediator of DNA damage checkpoint protein 1
total genus 22
structure length 108
sequence length 108
ec nomenclature
pdb deposition date 2011-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 3unnA00
1MZKA 1LGPA 3PO8A 4JONA 3UV0A 1J4LA 3VA4A 2G1LA 2JQIA 3GQSA 3UNNA 4H87A 1J4QA 1J4OA 2KB3A 2XT9B 1K2MA 3UOTA 4QCJA 4EGXA 5A8IA 4D9VA 3OUNA 1K2NA 3POAA 2JKDA 2LC1A 1LGQA 2A0TA 1R21A 1QU5A 2KKLA 3VPYA 1FHRA 1J4PA 1UJXA 1K3NA 1FHQA 4G2SA 1G6GA 2W3OA 3VA1A 3I0MA 3UN0A 1UHTA 1YJ5C 4EJQA 5E50A 3KT9A 4A0EA 1WV3A 3UMZA 2JPEA 1WLNA 2JQJA 2FF4A 2JQLA 1J4KA 3HUEA 3I0NA 2EH0A 3HUFA 2AFFA 1K3JA 3HX1A 2KB4A 3FM8A 1YJMA 2BRFA 1GXCA 3I6UA 3UNMA 3ELVA 2FEZA 1G3GA 5DJOA 1DMZA 3I6WA 2PIEA 3MDBA 2CSWA 1K3QA 3ELSA 2KFUA
chains in the Genus database with same CATH superfamily
1U7FB 1MZKA 2I1WA 1LGPA 3V8QA 1Y3IA 5EJFA 3PO8A 4JONA 3UV0A 1J4LA 1J2FA 3V8NA 3VA4A 5DHQA 2BONA 2G1LA 2JGRA 2JQIA 3GQSA 3A77A 3UNNA 4H87A 1QWTA 2AN1A 1J4QA 1J4OA 3V80A 2QV7A 2KB3A 4V24A 5JEOA 4JIWD 5C4VA 2XT9B 1K2MA 2QVLA 3UOTA 4QCJA 1U7FA 4EGXA 5A8IA 4D9VA 3V7WA 3OUNA 1K2NA 2XXSA 3V8RA 3POAA 2JKDA 2I2CA 2LC1A 1LGQA 4WERA 2A0TA 4JIVD 5EJIA 1R21A 1QU5A 2KKLA 3S40A 3VPYA 1FHRA 4HAOA 1J4PA 1UJXA 1K3NA 1FHQA 4G2SA 1G6GA 2W3OA 3VA1A 2I2BA 3I0MA 4L02A 1UHTA 3UN0A 5BVIA 4R9PA 1SUWA 4A4YA 1YJ5C 3VZBA 1YGSA 2P1RA 3DITA 4EJQA 5E50A 3KT9A 4A0EA 2I2AA 1U7VB 1KHXA 1ZOQA 1WV3A 5DHPA 1Z0ZA 3T5PA 3UMZA 4DY6A 1DEVA 2JPEA 1MJSA 1YT5A 5DHUA 5JERA 1WLNA 3V8PA 5DHRA 3AFOA 2JQJA 1G88A 5EJGA 2FF4A 2JQLA 3V7UA 1J4KA 3GMJA 3VZDA 3HUEA 4KU0D 1KHUA 1U0RA 2I2DA 3I0NA 1Y3HA 3VZCA 5DHTA 4WRRA 2EH0A 3HUFA 1U7VA 2AFFA 1K3JA 3HX1A 2KB4A 3FM8A 1U0TA 1YJMA 2BRFA 1Z0UA 5EJHA 3PFNA 1DD1A 1GXCA 1MR1A 2Q5FA 3DSHA 3I6UA 3V8MA 3UNMA 3ELVA 5JEKA 2FEZA 5JEMA 1MK2A 1G3GA 5DHSA 5DJOA 1DMZA 3I6WA 2PIEA 3MDBA 5JELA 1Z0SA 2CSWA 2I29A 1K3QA 3ELSA 2I2FA 3V7YA 5JEJA 2KFUA
chains in the Genus database with same CATH topology
1U7FB 1MZKA 1LGPA 3PO8A 4JONA 3UV0A 1J4LA 1J2FA 3VA4A 2BONA 2G1LA 2JGRA 2JQIA 3GQSA 3A77A 3UNNA 4H87A 1QWTA 1J4QA 1J4OA 2QV7A 2KB3A 4V24A 5JEOA 4JIWD 5C4VA 2XT9B 1K2MA 2QVLA 3UOTA 4QCJA 1U7FA 4EGXA 5A8IA 4D9VA 3OUNA 1K2NA 2XXSA 3POAA 2JKDA 2LC1A 1LGQA 4WERA 2A0TA 4JIVD 1R21A 1QU5A 2KKLA 3S40A 3VPYA 1FHRA 1J4PA 1UJXA 1K3NA 1FHQA 4G2SA 1G6GA 2W3OA 3VA1A 4L02A 3I0MA 3UN0A 1UHTA 5BVIA 4R9PA 4A4YA 1YJ5C 3VZBA 1YGSA 3DITA 2P1RA 4EJQA 5E50A 3KT9A 4A0EA 1U7VB 1KHXA 1ZOQA 1WV3A 3T5PA 3UMZA 1DEVA 2JPEA 1MJSA 5JERA 1WLNA 2JQJA 1G88A 2FF4A 2JQLA 1J4KA 3GMJA 3VZDA 3HUEA 4KU0D 1KHUA 3I0NA 3VZCA 4WRRA 2EH0A 3HUFA 1U7VA 2AFFA 1K3JA 3HX1A 2KB4A 3FM8A 1YJMA 2BRFA 1DD1A 1GXCA 1MR1A 3DSHA 3I6UA 3UNMA 3ELVA 5JEKA 2FEZA 5JEMA 1MK2A 1G3GA 5DJOA 1DMZA 3I6WA 2PIEA 3MDBA 5JELA 2CSWA 1K3QA 3ELSA 5JEJA 2KFUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MZK A;  1LGP A;  3PO8 A;  4JON A;  3UV0 A;  1J4L A;  3VA4 A;  2G1L A;  2JQI A;  3GQS A;  3UNN A;  4H87 A;  1J4Q A;  1J4O A;  2KB3 A;  2XT9 B;  1K2M A;  3UOT A;  4QCJ A;  4EGX A;  5A8I A;  4D9V A;  3OUN A;  1K2N A;  3POA A;  2JKD A;  2LC1 A;  1LGQ A;  2A0T A;  1R21 A;  1QU5 A;  2KKL A;  3VPY A;  1FHR A;  1J4P A;  1UJX A;  1K3N A;  1FHQ A;  4G2S A;  1G6G A;  2W3O A;  3VA1 A;  3I0M A;  3UN0 A;  1UHT A;  1YJ5 C;  4EJQ A;  5E50 A;  3KT9 A;  4A0E A;  1WV3 A;  3UMZ A;  2JPE A;  1WLN A;  2JQJ A;  2FF4 A;  2JQL A;  1J4K A;  3HUE A;  3I0N A;  2EH0 A;  3HUF A;  2AFF A;  1K3J A;  3HX1 A;  2KB4 A;  3FM8 A;  1YJM A;  2BRF A;  1GXC A;  3I6U A;  3UNM A;  3ELV A;  2FEZ A;  1G3G A;  5DJO A;  1DMZ A;  3I6W A;  2PIE A;  3MDB A;  2CSW A;  1K3Q A;  3ELS A;  2KFU A; 
#chains in the Genus database with same CATH topology
 1U7F B;  1MZK A;  2I1W A;  1LGP A;  3V8Q A;  1Y3I A;  5EJF A;  3PO8 A;  4JON A;  3UV0 A;  1J4L A;  1J2F A;  3V8N A;  3VA4 A;  5DHQ A;  2BON A;  2G1L A;  2JGR A;  2JQI A;  3GQS A;  3A77 A;  3UNN A;  4H87 A;  1QWT A;  2AN1 A;  1J4Q A;  1J4O A;  3V80 A;  2QV7 A;  2KB3 A;  4V24 A;  5JEO A;  4JIW D;  5C4V A;  2XT9 B;  1K2M A;  2QVL A;  3UOT A;  4QCJ A;  1U7F A;  4EGX A;  5A8I A;  4D9V A;  3V7W A;  3OUN A;  1K2N A;  2XXS A;  3V8R A;  3POA A;  2JKD A;  2I2C A;  2LC1 A;  1LGQ A;  4WER A;  2A0T A;  4JIV D;  5EJI A;  1R21 A;  1QU5 A;  2KKL A;  3S40 A;  3VPY A;  1FHR A;  4HAO A;  1J4P A;  1UJX A;  1K3N A;  1FHQ A;  4G2S A;  1G6G A;  2W3O A;  3VA1 A;  2I2B A;  3I0M A;  4L02 A;  1UHT A;  3UN0 A;  5BVI A;  4R9P A;  1SUW A;  4A4Y A;  1YJ5 C;  3VZB A;  1YGS A;  2P1R A;  3DIT A;  4EJQ A;  5E50 A;  3KT9 A;  4A0E A;  2I2A A;  1U7V B;  1KHX A;  1ZOQ A;  1WV3 A;  5DHP A;  1Z0Z A;  3T5P A;  3UMZ A;  4DY6 A;  1DEV A;  2JPE A;  1MJS A;  1YT5 A;  5DHU A;  5JER A;  1WLN A;  3V8P A;  5DHR A;  3AFO A;  2JQJ A;  1G88 A;  5EJG A;  2FF4 A;  2JQL A;  3V7U A;  1J4K A;  3GMJ A;  3VZD A;  3HUE A;  4KU0 D;  1KHU A;  1U0R A;  2I2D A;  3I0N A;  1Y3H A;  3VZC A;  5DHT A;  4WRR A;  2EH0 A;  3HUF A;  1U7V A;  2AFF A;  1K3J A;  3HX1 A;  2KB4 A;  3FM8 A;  1U0T A;  1YJM A;  2BRF A;  1Z0U A;  5EJH A;  3PFN A;  1DD1 A;  1GXC A;  1MR1 A;  2Q5F A;  3DSH A;  3I6U A;  3V8M A;  3UNM A;  3ELV A;  5JEK A;  2FEZ A;  5JEM A;  1MK2 A;  1G3G A;  5DHS A;  5DJO A;  1DMZ A;  3I6W A;  2PIE A;  3MDB A;  5JEL A;  1Z0S A;  2CSW A;  2I29 A;  1K3Q A;  3ELS A;  2I2F A;  3V7Y A;  5JEJ A;  2KFU A; 
#chains in the Genus database with same CATH homology
 1U7F B;  1MZK A;  1LGP A;  3PO8 A;  4JON A;  3UV0 A;  1J4L A;  1J2F A;  3VA4 A;  2BON A;  2G1L A;  2JGR A;  2JQI A;  3GQS A;  3A77 A;  3UNN A;  4H87 A;  1QWT A;  1J4Q A;  1J4O A;  2QV7 A;  2KB3 A;  4V24 A;  5JEO A;  4JIW D;  5C4V A;  2XT9 B;  1K2M A;  2QVL A;  3UOT A;  4QCJ A;  1U7F A;  4EGX A;  5A8I A;  4D9V A;  3OUN A;  1K2N A;  2XXS A;  3POA A;  2JKD A;  2LC1 A;  1LGQ A;  4WER A;  2A0T A;  4JIV D;  1R21 A;  1QU5 A;  2KKL A;  3S40 A;  3VPY A;  1FHR A;  1J4P A;  1UJX A;  1K3N A;  1FHQ A;  4G2S A;  1G6G A;  2W3O A;  3VA1 A;  4L02 A;  3I0M A;  3UN0 A;  1UHT A;  5BVI A;  4R9P A;  4A4Y A;  1YJ5 C;  3VZB A;  1YGS A;  3DIT A;  2P1R A;  4EJQ A;  5E50 A;  3KT9 A;  4A0E A;  1U7V B;  1KHX A;  1ZOQ A;  1WV3 A;  3T5P A;  3UMZ A;  1DEV A;  2JPE A;  1MJS A;  5JER A;  1WLN A;  2JQJ A;  1G88 A;  2FF4 A;  2JQL A;  1J4K A;  3GMJ A;  3VZD A;  3HUE A;  4KU0 D;  1KHU A;  3I0N A;  3VZC A;  4WRR A;  2EH0 A;  3HUF A;  1U7V A;  2AFF A;  1K3J A;  3HX1 A;  2KB4 A;  3FM8 A;  1YJM A;  2BRF A;  1DD1 A;  1GXC A;  1MR1 A;  3DSH A;  3I6U A;  3UNM A;  3ELV A;  5JEK A;  2FEZ A;  5JEM A;  1MK2 A;  1G3G A;  5DJO A;  1DMZ A;  3I6W A;  2PIE A;  3MDB A;  5JEL A;  2CSW A;  1K3Q A;  3ELS A;  5JEJ A;  2KFU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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