3UV0A

Crystal structure of the drosophila mu2 fha domain
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
97
structure length
97
Chain Sequence
DVSLFFGGLPAILLKADTIYRIGRQKGLEISIADESMELAHATACILRRGVVRLAALVGKIFVNDQEETVVDIGMENAVAGKVKLRFGNVEARLEFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Dimerization, but not phosphothreonine binding, is conserved between the forkhead-associated domains of Drosophila MU2 and human MDC1
pubmed doi rcsb
molecule tags Protein binding
source organism Drosophila melanogaster
molecule keywords Mutator 2, isoform B
total genus 19
structure length 97
sequence length 97
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-11-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18221 MU2_FHA Mutator 2 Fork head associated domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 3uv0A00
5DJOA 4D9VA 1QU5A 4H87A 2PIEA 1K3QA 2JQIA 3PO8A 3VA4A 3UNMA 2JQLA 1GXCA 4QCJA 1MZKA 3ELVA 2AFFA 3HUEA 3UNNA 3VPYA 2EH0A 1G6GA 1R21A 1UHTA 1FHRA 3HX1A 1UJXA 3KT9A 2BRFA 2A0TA 2LC1A 3UOTA 1FHQA 2KB4A 2CSWA 4EGXA 4EJQA 4JONA 3ELSA 2FEZA 2JQJA 3MDBA 1YJ5C 1J4KA 3OUNA 4G2SA 1K2MA 1J4PA 1J4LA 3UN0A 3FM8A 1K2NA 2FF4A 3I6UA 1LGQA 1J4QA 3UV0A 3VA1A 1WLNA 1K3JA 3I0MA 2JKDA 5A8IA 3GQSA 3I0NA 1J4OA 2KFUA 1WV3A 5E50A 2JPEA 2KKLA 3UMZA 2W3OA 2XT9B 3I6WA 3HUFA 1YJMA 1G3GA 1K3NA 3POAA 2KB3A 4A0EA 2G1LA 1LGPA 1DMZA
chains in the Genus database with same CATH superfamily
5DJOA 4D9VA 1QU5A 4H87A 1Z0ZA 5C4VA 2PIEA 1Z0UA 1U0RA 1U7FB 1K3QA 2JQIA 3PO8A 3VA4A 3UNMA 2JGRA 4WERA 3VZBA 3A77A 2QV7A 4JIWD 3DSHA 5EJHA 2JQLA 1GXCA 1ZOQA 4QCJA 3PFNA 4DY6A 1MZKA 3ELVA 2AFFA 5DHQA 2P1RA 3HUEA 5JEJA 2Q5FA 1U0TA 2I29A 3V8RA 3UNNA 2I2FA 3VPYA 5EJIA 2EH0A 1G6GA 1R21A 1U7FA 1UHTA 3V8QA 1YGSA 5JELA 1FHRA 1Y3IA 1UJXA 3HX1A 2I1WA 3KT9A 2AN1A 1Z0SA 2BRFA 5EJGA 2A0TA 5JEMA 5JEKA 2LC1A 5EJFA 3UOTA 1FHQA 3DITA 4A4YA 2KB4A 2CSWA 2I2DA 1MR1A 4EGXA 1DD1A 4EJQA 5DHPA 3V8MA 4JONA 3ELSA 1MJSA 5BVIA 2FEZA 4WRRA 2JQJA 1QWTA 3MDBA 3V8NA 2QVLA 1YJ5C 1J4KA 3OUNA 3V7WA 4G2SA 3VZDA 1J4PA 1J4LA 3VZCA 1K2MA 3UN0A 3FM8A 1K2NA 2FF4A 3I6UA 1J2FA 1LGQA 1J4QA 3UV0A 3VA1A 1WLNA 4HAOA 3T5PA 1DMZA 1U7VB 1K3JA 4V24A 5DHUA 1DEVA 2JKDA 1KHXA 1Y3HA 3I0MA 4JIVD 5A8IA 2BONA 3GQSA 2I2BA 3I0NA 1J4OA 5DHSA 3GMJA 1SUWA 3AFOA 2KFUA 2I2CA 1MK2A 1WV3A 1G88A 5E50A 2JPEA 3S40A 3V80A 2I2AA 5JERA 2XXSA 5DHTA 2KKLA 3UMZA 1KHUA 2W3OA 2XT9B 1YT5A 4L02A 5JEOA 3I6WA 3V7YA 3HUFA 3V8PA 1YJMA 4R9PA 1G3GA 1K3NA 5DHRA 3POAA 4KU0D 2KB3A 4A0EA 2G1LA 1LGPA 3V7UA 1U7VA
chains in the Genus database with same CATH topology
5DJOA 4D9VA 1QU5A 4H87A 5C4VA 2PIEA 1U7FB 1K3QA 2JQIA 3PO8A 3VA4A 3UNMA 2JGRA 4WERA 3VZBA 3A77A 2QV7A 4JIWD 3DSHA 2JQLA 1GXCA 1ZOQA 4QCJA 1MZKA 3ELVA 2AFFA 2P1RA 3HUEA 5JEJA 3UNNA 3VPYA 5JELA 2EH0A 1G6GA 1R21A 1U7FA 1UHTA 1FHRA 1YGSA 3HX1A 1UJXA 3KT9A 2BRFA 2A0TA 5JEMA 5JEKA 2LC1A 3UOTA 1FHQA 3DITA 4A4YA 2KB4A 2CSWA 1MR1A 4EGXA 1DD1A 4EJQA 4JONA 3ELSA 1MJSA 5BVIA 2FEZA 4WRRA 2JQJA 1QWTA 3MDBA 2QVLA 1YJ5C 1J4KA 3OUNA 3VZDA 4G2SA 1K2MA 1J4PA 1J4LA 3VZCA 3UN0A 3FM8A 1K2NA 2FF4A 3I6UA 1J2FA 1LGQA 1J4QA 3UV0A 3VA1A 1WLNA 3T5PA 1U7VB 1K3JA 4V24A 1DEVA 2JKDA 3I0MA 1KHXA 4JIVD 5A8IA 2BONA 3GQSA 3I0NA 1J4OA 3GMJA 2KFUA 1MK2A 1WV3A 1G88A 5E50A 2JPEA 3S40A 5JERA 2XXSA 2KKLA 3UMZA 1KHUA 2W3OA 2XT9B 5JEOA 4L02A 3I6WA 3HUFA 1YJMA 4R9PA 1G3GA 1K3NA 3POAA 4KU0D 2KB3A 4A0EA 2G1LA 1LGPA 1DMZA 1U7VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DJO A;  4D9V A;  1QU5 A;  4H87 A;  2PIE A;  1K3Q A;  2JQI A;  3PO8 A;  3VA4 A;  3UNM A;  2JQL A;  1GXC A;  4QCJ A;  1MZK A;  3ELV A;  2AFF A;  3HUE A;  3UNN A;  3VPY A;  2EH0 A;  1G6G A;  1R21 A;  1UHT A;  1FHR A;  3HX1 A;  1UJX A;  3KT9 A;  2BRF A;  2A0T A;  2LC1 A;  3UOT A;  1FHQ A;  2KB4 A;  2CSW A;  4EGX A;  4EJQ A;  4JON A;  3ELS A;  2FEZ A;  2JQJ A;  3MDB A;  1YJ5 C;  1J4K A;  3OUN A;  4G2S A;  1K2M A;  1J4P A;  1J4L A;  3UN0 A;  3FM8 A;  1K2N A;  2FF4 A;  3I6U A;  1LGQ A;  1J4Q A;  3UV0 A;  3VA1 A;  1WLN A;  1K3J A;  3I0M A;  2JKD A;  5A8I A;  3GQS A;  3I0N A;  1J4O A;  2KFU A;  1WV3 A;  5E50 A;  2JPE A;  2KKL A;  3UMZ A;  2W3O A;  2XT9 B;  3I6W A;  3HUF A;  1YJM A;  1G3G A;  1K3N A;  3POA A;  2KB3 A;  4A0E A;  2G1L A;  1LGP A;  1DMZ A; 
#chains in the Genus database with same CATH topology
 5DJO A;  4D9V A;  1QU5 A;  4H87 A;  1Z0Z A;  5C4V A;  2PIE A;  1Z0U A;  1U0R A;  1U7F B;  1K3Q A;  2JQI A;  3PO8 A;  3VA4 A;  3UNM A;  2JGR A;  4WER A;  3VZB A;  3A77 A;  2QV7 A;  4JIW D;  3DSH A;  5EJH A;  2JQL A;  1GXC A;  1ZOQ A;  4QCJ A;  3PFN A;  4DY6 A;  1MZK A;  3ELV A;  2AFF A;  5DHQ A;  2P1R A;  3HUE A;  5JEJ A;  2Q5F A;  1U0T A;  2I29 A;  3V8R A;  3UNN A;  2I2F A;  3VPY A;  5EJI A;  2EH0 A;  1G6G A;  1R21 A;  1U7F A;  1UHT A;  3V8Q A;  1YGS A;  5JEL A;  1FHR A;  1Y3I A;  1UJX A;  3HX1 A;  2I1W A;  3KT9 A;  2AN1 A;  1Z0S A;  2BRF A;  5EJG A;  2A0T A;  5JEM A;  5JEK A;  2LC1 A;  5EJF A;  3UOT A;  1FHQ A;  3DIT A;  4A4Y A;  2KB4 A;  2CSW A;  2I2D A;  1MR1 A;  4EGX A;  1DD1 A;  4EJQ A;  5DHP A;  3V8M A;  4JON A;  3ELS A;  1MJS A;  5BVI A;  2FEZ A;  4WRR A;  2JQJ A;  1QWT A;  3MDB A;  3V8N A;  2QVL A;  1YJ5 C;  1J4K A;  3OUN A;  3V7W A;  4G2S A;  3VZD A;  1J4P A;  1J4L A;  3VZC A;  1K2M A;  3UN0 A;  3FM8 A;  1K2N A;  2FF4 A;  3I6U A;  1J2F A;  1LGQ A;  1J4Q A;  3UV0 A;  3VA1 A;  1WLN A;  4HAO A;  3T5P A;  1DMZ A;  1U7V B;  1K3J A;  4V24 A;  5DHU A;  1DEV A;  2JKD A;  1KHX A;  1Y3H A;  3I0M A;  4JIV D;  5A8I A;  2BON A;  3GQS A;  2I2B A;  3I0N A;  1J4O A;  5DHS A;  3GMJ A;  1SUW A;  3AFO A;  2KFU A;  2I2C A;  1MK2 A;  1WV3 A;  1G88 A;  5E50 A;  2JPE A;  3S40 A;  3V80 A;  2I2A A;  5JER A;  2XXS A;  5DHT A;  2KKL A;  3UMZ A;  1KHU A;  2W3O A;  2XT9 B;  1YT5 A;  4L02 A;  5JEO A;  3I6W A;  3V7Y A;  3HUF A;  3V8P A;  1YJM A;  4R9P A;  1G3G A;  1K3N A;  5DHR A;  3POA A;  4KU0 D;  2KB3 A;  4A0E A;  2G1L A;  1LGP A;  3V7U A;  1U7V A; 
#chains in the Genus database with same CATH homology
 5DJO A;  4D9V A;  1QU5 A;  4H87 A;  5C4V A;  2PIE A;  1U7F B;  1K3Q A;  2JQI A;  3PO8 A;  3VA4 A;  3UNM A;  2JGR A;  4WER A;  3VZB A;  3A77 A;  2QV7 A;  4JIW D;  3DSH A;  2JQL A;  1GXC A;  1ZOQ A;  4QCJ A;  1MZK A;  3ELV A;  2AFF A;  2P1R A;  3HUE A;  5JEJ A;  3UNN A;  3VPY A;  5JEL A;  2EH0 A;  1G6G A;  1R21 A;  1U7F A;  1UHT A;  1FHR A;  1YGS A;  3HX1 A;  1UJX A;  3KT9 A;  2BRF A;  2A0T A;  5JEM A;  5JEK A;  2LC1 A;  3UOT A;  1FHQ A;  3DIT A;  4A4Y A;  2KB4 A;  2CSW A;  1MR1 A;  4EGX A;  1DD1 A;  4EJQ A;  4JON A;  3ELS A;  1MJS A;  5BVI A;  2FEZ A;  4WRR A;  2JQJ A;  1QWT A;  3MDB A;  2QVL A;  1YJ5 C;  1J4K A;  3OUN A;  3VZD A;  4G2S A;  1K2M A;  1J4P A;  1J4L A;  3VZC A;  3UN0 A;  3FM8 A;  1K2N A;  2FF4 A;  3I6U A;  1J2F A;  1LGQ A;  1J4Q A;  3UV0 A;  3VA1 A;  1WLN A;  3T5P A;  1U7V B;  1K3J A;  4V24 A;  1DEV A;  2JKD A;  3I0M A;  1KHX A;  4JIV D;  5A8I A;  2BON A;  3GQS A;  3I0N A;  1J4O A;  3GMJ A;  2KFU A;  1MK2 A;  1WV3 A;  1G88 A;  5E50 A;  2JPE A;  3S40 A;  5JER A;  2XXS A;  2KKL A;  3UMZ A;  1KHU A;  2W3O A;  2XT9 B;  5JEO A;  4L02 A;  3I6W A;  3HUF A;  1YJM A;  4R9P A;  1G3G A;  1K3N A;  3POA A;  4KU0 D;  2KB3 A;  4A0E A;  2G1L A;  1LGP A;  1DMZ A;  1U7V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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