4JONA

Crystal structure of a centrosomal protein 170kda, transcript variant beta (cep170) from homo sapiens at 2.15 a resolution (psi community target, sundstrom)
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
122
structure length
122
Chain Sequence
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a centrosomal protein 170kDa, transcript variant beta (CEP170) from Homo sapiens at 2.15 A resolution (PSI Community Target, Sundstrom)
rcsb
molecule tags Structural genomics, unknown function
source organism Homo sapiens
molecule keywords Centrosomal protein of 170 kDa
total genus 30
structure length 122
sequence length 122
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2013-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 4jonA00
1K3JA 1YJMA 3ELSA 3VA4A 1WLNA 3UNMA 1MZKA 1J4OA 1GXCA 2LC1A 1G6GA 1K3NA 3HUEA 1K2MA 1J4PA 1FHQA 3I0NA 1J4QA 1QU5A 3UV0A 1LGPA 3UMZA 2XT9B 4JONA 2W3OA 1J4LA 2KKLA 3UOTA 4EJQA 2JQJA 3UN0A 1LGQA 4QCJA 2CSWA 2BRFA 3VPYA 2FF4A 3POAA 1K3QA 2JKDA 4H87A 3OUNA 1UJXA 4EGXA 3VA1A 1R21A 3I6WA 3I0MA 4G2SA 2KB4A 3PO8A 2EH0A 2PIEA 2G1LA 2A0TA 1J4KA 3HUFA 3GQSA 4D9VA 3I6UA 3KT9A 2KFUA 3MDBA 5E50A 5DJOA 3UNNA 2FEZA 1FHRA 3FM8A 2JPEA 1UHTA 1G3GA 2JQLA 2AFFA 5A8IA 1K2NA 3HX1A 2JQIA 3ELVA 4A0EA 1DMZA 2KB3A 1YJ5C 1WV3A
chains in the Genus database with same CATH superfamily
5DHQA 1K3JA 4L02A 1YJMA 4WERA 5C4VA 3ELSA 4JIWD 3VA4A 1ZOQA 1WLNA 3DITA 4KU0D 3UNMA 1MZKA 2AN1A 5DHRA 1J4OA 1DEVA 1MK2A 4V24A 1GXCA 2LC1A 1G6GA 1K3NA 3HUEA 1K2MA 1U7FA 2I29A 3GMJA 1J2FA 5JELA 1J4PA 3V7YA 1FHQA 3V80A 1U7VA 3I0NA 4HAOA 3V8NA 3V8PA 5EJFA 1Z0ZA 3V8MA 1J4QA 1QU5A 3AFOA 3UV0A 5EJGA 3VZCA 1YGSA 1Z0UA 4R9PA 1LGPA 3UMZA 2BONA 3PFNA 3A77A 2XT9B 1U0RA 2P1RA 1MR1A 4JONA 3S40A 2W3OA 1J4LA 2KKLA 3UOTA 5BVIA 5DHPA 2Q5FA 4EJQA 2JQJA 1G88A 1LGQA 4QCJA 3DSHA 3UN0A 2QVLA 2CSWA 5EJIA 1Y3HA 2BRFA 3VPYA 2FF4A 3POAA 5DHUA 1K3QA 2JKDA 5JEMA 4H87A 3OUNA 3V7WA 1UJXA 3VZBA 4EGXA 2XXSA 3VA1A 1R21A 4JIVD 1QWTA 3I6WA 4DY6A 3I0MA 5DHTA 4G2SA 4A4YA 2I2DA 2KB4A 3PO8A 2EH0A 1U7FB 2PIEA 2G1LA 1U0TA 2A0TA 1KHUA 5DHSA 1J4KA 3HUFA 3GQSA 5JEOA 1SUWA 3T5PA 1U7VB 2JGRA 4D9VA 3I6UA 3KT9A 1YT5A 2KFUA 3MDBA 5JERA 5E50A 5EJHA 1KHXA 5DJOA 3UNNA 3V8RA 2FEZA 1FHRA 1DD1A 3FM8A 2JPEA 3V7UA 1UHTA 1G3GA 2I2FA 2I2BA 2JQLA 2AFFA 5A8IA 3V8QA 5JEKA 1MJSA 1K2NA 5JEJA 4WRRA 3VZDA 1YJ5C 2I2AA 3HX1A 2JQIA 2I1WA 3ELVA 4A0EA 1DMZA 2I2CA 1Z0SA 2KB3A 2QV7A 1WV3A 1Y3IA
chains in the Genus database with same CATH topology
1K3JA 4L02A 1YJMA 4WERA 5C4VA 3ELSA 4JIWD 3VA4A 1ZOQA 1WLNA 3DITA 4KU0D 3UNMA 1MZKA 1J4OA 1DEVA 1MK2A 4V24A 1GXCA 2LC1A 1G6GA 1K3NA 3HUEA 1K2MA 1U7FA 3GMJA 1J2FA 5JELA 1J4PA 1FHQA 1U7VA 3I0NA 1J4QA 1QU5A 3UV0A 3VZCA 1YGSA 4R9PA 1LGPA 3UMZA 2BONA 2XT9B 3A77A 2P1RA 1MR1A 4JONA 3S40A 2W3OA 1J4LA 2KKLA 3UOTA 5BVIA 4EJQA 2JQJA 1G88A 1LGQA 4QCJA 3DSHA 3UN0A 2QVLA 2CSWA 2BRFA 3VPYA 2FF4A 3POAA 1K3QA 2JKDA 5JEMA 4H87A 3OUNA 1UJXA 3VZBA 4EGXA 2XXSA 3VA1A 1R21A 4JIVD 1QWTA 3I6WA 3I0MA 4G2SA 4A4YA 2KB4A 3PO8A 2EH0A 1U7FB 2PIEA 2G1LA 2A0TA 1KHUA 1J4KA 3HUFA 3GQSA 5JEOA 3T5PA 1U7VB 2JGRA 4D9VA 3I6UA 3KT9A 2KFUA 3MDBA 5JERA 5E50A 1KHXA 5DJOA 3UNNA 2FEZA 1FHRA 1DD1A 3FM8A 2JPEA 1UHTA 1G3GA 2JQLA 2AFFA 5A8IA 5JEKA 1MJSA 1K2NA 5JEJA 4WRRA 3VZDA 1YJ5C 3HX1A 2JQIA 3ELVA 4A0EA 1DMZA 2KB3A 2QV7A 1WV3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K3J A;  1YJM A;  3ELS A;  3VA4 A;  1WLN A;  3UNM A;  1MZK A;  1J4O A;  1GXC A;  2LC1 A;  1G6G A;  1K3N A;  3HUE A;  1K2M A;  1J4P A;  1FHQ A;  3I0N A;  1J4Q A;  1QU5 A;  3UV0 A;  1LGP A;  3UMZ A;  2XT9 B;  4JON A;  2W3O A;  1J4L A;  2KKL A;  3UOT A;  4EJQ A;  2JQJ A;  3UN0 A;  1LGQ A;  4QCJ A;  2CSW A;  2BRF A;  3VPY A;  2FF4 A;  3POA A;  1K3Q A;  2JKD A;  4H87 A;  3OUN A;  1UJX A;  4EGX A;  3VA1 A;  1R21 A;  3I6W A;  3I0M A;  4G2S A;  2KB4 A;  3PO8 A;  2EH0 A;  2PIE A;  2G1L A;  2A0T A;  1J4K A;  3HUF A;  3GQS A;  4D9V A;  3I6U A;  3KT9 A;  2KFU A;  3MDB A;  5E50 A;  5DJO A;  3UNN A;  2FEZ A;  1FHR A;  3FM8 A;  2JPE A;  1UHT A;  1G3G A;  2JQL A;  2AFF A;  5A8I A;  1K2N A;  3HX1 A;  2JQI A;  3ELV A;  4A0E A;  1DMZ A;  2KB3 A;  1YJ5 C;  1WV3 A; 
#chains in the Genus database with same CATH topology
 5DHQ A;  1K3J A;  4L02 A;  1YJM A;  4WER A;  5C4V A;  3ELS A;  4JIW D;  3VA4 A;  1ZOQ A;  1WLN A;  3DIT A;  4KU0 D;  3UNM A;  1MZK A;  2AN1 A;  5DHR A;  1J4O A;  1DEV A;  1MK2 A;  4V24 A;  1GXC A;  2LC1 A;  1G6G A;  1K3N A;  3HUE A;  1K2M A;  1U7F A;  2I29 A;  3GMJ A;  1J2F A;  5JEL A;  1J4P A;  3V7Y A;  1FHQ A;  3V80 A;  1U7V A;  3I0N A;  4HAO A;  3V8N A;  3V8P A;  5EJF A;  1Z0Z A;  3V8M A;  1J4Q A;  1QU5 A;  3AFO A;  3UV0 A;  5EJG A;  3VZC A;  1YGS A;  1Z0U A;  4R9P A;  1LGP A;  3UMZ A;  2BON A;  3PFN A;  3A77 A;  2XT9 B;  1U0R A;  2P1R A;  1MR1 A;  4JON A;  3S40 A;  2W3O A;  1J4L A;  2KKL A;  3UOT A;  5BVI A;  5DHP A;  2Q5F A;  4EJQ A;  2JQJ A;  1G88 A;  1LGQ A;  4QCJ A;  3DSH A;  3UN0 A;  2QVL A;  2CSW A;  5EJI A;  1Y3H A;  2BRF A;  3VPY A;  2FF4 A;  3POA A;  5DHU A;  1K3Q A;  2JKD A;  5JEM A;  4H87 A;  3OUN A;  3V7W A;  1UJX A;  3VZB A;  4EGX A;  2XXS A;  3VA1 A;  1R21 A;  4JIV D;  1QWT A;  3I6W A;  4DY6 A;  3I0M A;  5DHT A;  4G2S A;  4A4Y A;  2I2D A;  2KB4 A;  3PO8 A;  2EH0 A;  1U7F B;  2PIE A;  2G1L A;  1U0T A;  2A0T A;  1KHU A;  5DHS A;  1J4K A;  3HUF A;  3GQS A;  5JEO A;  1SUW A;  3T5P A;  1U7V B;  2JGR A;  4D9V A;  3I6U A;  3KT9 A;  1YT5 A;  2KFU A;  3MDB A;  5JER A;  5E50 A;  5EJH A;  1KHX A;  5DJO A;  3UNN A;  3V8R A;  2FEZ A;  1FHR A;  1DD1 A;  3FM8 A;  2JPE A;  3V7U A;  1UHT A;  1G3G A;  2I2F A;  2I2B A;  2JQL A;  2AFF A;  5A8I A;  3V8Q A;  5JEK A;  1MJS A;  1K2N A;  5JEJ A;  4WRR A;  3VZD A;  1YJ5 C;  2I2A A;  3HX1 A;  2JQI A;  2I1W A;  3ELV A;  4A0E A;  1DMZ A;  2I2C A;  1Z0S A;  2KB3 A;  2QV7 A;  1WV3 A;  1Y3I A; 
#chains in the Genus database with same CATH homology
 1K3J A;  4L02 A;  1YJM A;  4WER A;  5C4V A;  3ELS A;  4JIW D;  3VA4 A;  1ZOQ A;  1WLN A;  3DIT A;  4KU0 D;  3UNM A;  1MZK A;  1J4O A;  1DEV A;  1MK2 A;  4V24 A;  1GXC A;  2LC1 A;  1G6G A;  1K3N A;  3HUE A;  1K2M A;  1U7F A;  3GMJ A;  1J2F A;  5JEL A;  1J4P A;  1FHQ A;  1U7V A;  3I0N A;  1J4Q A;  1QU5 A;  3UV0 A;  3VZC A;  1YGS A;  4R9P A;  1LGP A;  3UMZ A;  2BON A;  2XT9 B;  3A77 A;  2P1R A;  1MR1 A;  4JON A;  3S40 A;  2W3O A;  1J4L A;  2KKL A;  3UOT A;  5BVI A;  4EJQ A;  2JQJ A;  1G88 A;  1LGQ A;  4QCJ A;  3DSH A;  3UN0 A;  2QVL A;  2CSW A;  2BRF A;  3VPY A;  2FF4 A;  3POA A;  1K3Q A;  2JKD A;  5JEM A;  4H87 A;  3OUN A;  1UJX A;  3VZB A;  4EGX A;  2XXS A;  3VA1 A;  1R21 A;  4JIV D;  1QWT A;  3I6W A;  3I0M A;  4G2S A;  4A4Y A;  2KB4 A;  3PO8 A;  2EH0 A;  1U7F B;  2PIE A;  2G1L A;  2A0T A;  1KHU A;  1J4K A;  3HUF A;  3GQS A;  5JEO A;  3T5P A;  1U7V B;  2JGR A;  4D9V A;  3I6U A;  3KT9 A;  2KFU A;  3MDB A;  5JER A;  5E50 A;  1KHX A;  5DJO A;  3UNN A;  2FEZ A;  1FHR A;  1DD1 A;  3FM8 A;  2JPE A;  1UHT A;  1G3G A;  2JQL A;  2AFF A;  5A8I A;  5JEK A;  1MJS A;  1K2N A;  5JEJ A;  4WRR A;  3VZD A;  1YJ5 C;  3HX1 A;  2JQI A;  3ELV A;  4A0E A;  1DMZ A;  2KB3 A;  2QV7 A;  1WV3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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