4JONA

Crystal structure of a centrosomal protein 170kda, transcript variant beta (cep170) from homo sapiens at 2.15 a resolution (psi community target, sundstrom)
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
122
structure length
122
Chain Sequence
MSLTSWFLVSSGGTRHRLPREMIFVGRDDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKLRFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a centrosomal protein 170kDa, transcript variant beta (CEP170) from Homo sapiens at 2.15 A resolution (PSI Community Target, Sundstrom)
rcsb
molecule tags Structural genomics, unknown function
source organism Homo sapiens
molecule keywords Centrosomal protein of 170 kDa
total genus 30
structure length 122
sequence length 122
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2013-03-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 4jonA00
2JKDA 3GQSA 1YJ5C 5A8IA 1FHQA 3HUFA 1G3GA 2KKLA 2JQIA 3ELVA 1UJXA 3UN0A 3UMZA 4JONA 2LC1A 2KB3A 4A0EA 2A0TA 1LGPA 2KB4A 2CSWA 3ELSA 1J4KA 1K3QA 3I0NA 1MZKA 4G2SA 2FF4A 4EJQA 3POAA 3OUNA 2PIEA 1QU5A 3VPYA 3VA4A 2AFFA 2FEZA 1J4LA 1UHTA 3UOTA 1LGQA 3PO8A 4D9VA 1J4QA 2G1LA 1GXCA 1K2NA 1K3NA 3UNMA 4QCJA 2KFUA 1K2MA 3MDBA 3FM8A 3I6WA 4EGXA 1YJMA 4H87A 1J4PA 1DMZA 2XT9B 2W3OA 1G6GA 1FHRA 1R21A 3HX1A 5E50A 2JPEA 3KT9A 3HUEA 2JQLA 1K3JA 2BRFA 3I6UA 3I0MA 1WLNA 3UNNA 1WV3A 2JQJA 3VA1A 3UV0A 2EH0A 1J4OA 5DJOA
chains in the Genus database with same CATH superfamily
2I2AA 3V80A 1U0RA 3V8RA 2JKDA 2P1RA 2I1WA 3GQSA 4R9PA 5EJIA 1YJ5C 5A8IA 1FHQA 3HUFA 1G3GA 5JEOA 1Z0UA 5DHSA 2KKLA 2I2DA 2JQIA 3ELVA 1UJXA 1YT5A 3PFNA 3UN0A 3DITA 4JONA 4JIVD 3GMJA 3UMZA 1J4OA 1Y3HA 2LC1A 2Q5FA 2KB3A 3DSHA 4A0EA 5JEJA 2A0TA 1LGPA 2XXSA 1DD1A 2QV7A 2KB4A 1U7FB 3A77A 2CSWA 5DHTA 3ELSA 3VZBA 3V7UA 1J4KA 2I2BA 3S40A 5DHPA 3V7YA 1K3QA 3I0NA 3V8QA 4WERA 1Y3IA 1MZKA 4G2SA 2FF4A 4EJQA 2I29A 3POAA 3OUNA 2PIEA 1QU5A 1DEVA 3VPYA 1KHUA 3VA4A 1ZOQA 4KU0D 2AFFA 2FEZA 1J4LA 1UHTA 5DHRA 2BONA 1KHXA 3UOTA 4HAOA 1LGQA 2QVLA 3PO8A 4D9VA 1J4QA 2G1LA 5EJFA 5JEMA 1SUWA 5EJHA 1GXCA 1K2NA 1K3NA 3UNMA 4QCJA 2KFUA 1K2MA 3MDBA 4A4YA 1Z0ZA 1YGSA 1MJSA 3FM8A 1U0TA 3I6WA 1YJMA 4EGXA 1QWTA 4H87A 1J4PA 5JEKA 1DMZA 2XT9B 5JELA 2W3OA 1G6GA 1U7VB 1FHRA 3V8NA 3VZCA 3AFOA 5C4VA 1R21A 3V8MA 1G88A 1U7FA 3HX1A 5E50A 1Z0SA 4JIWD 2JGRA 4WRRA 3V7WA 5JERA 3T5PA 5DHQA 2JPEA 1MR1A 3KT9A 4L02A 5DHUA 5BVIA 3HUEA 5EJGA 2JQLA 1J2FA 2I2FA 1K3JA 3V8PA 2BRFA 2AN1A 3I6UA 1MK2A 3I0MA 1WLNA 4V24A 3VZDA 3UNNA 2I2CA 1WV3A 2JQJA 3VA1A 3UV0A 4DY6A 2EH0A 1U7VA 5DJOA
chains in the Genus database with same CATH topology
2JKDA 2P1RA 3GQSA 4R9PA 1YJ5C 5A8IA 1FHQA 3HUFA 1G3GA 5JEOA 2KKLA 2JQIA 3ELVA 1UJXA 3UN0A 3UMZA 3DITA 4JONA 4JIVD 3GMJA 1J4OA 2LC1A 2KB3A 3DSHA 4A0EA 5JEJA 2A0TA 1LGPA 2XXSA 1DD1A 2QV7A 2KB4A 1U7FB 3A77A 2CSWA 3ELSA 3VZBA 1J4KA 3S40A 1K3QA 3I0NA 4WERA 1MZKA 4G2SA 2FF4A 4EJQA 3POAA 3OUNA 2PIEA 1QU5A 1DEVA 3VPYA 1KHUA 3VA4A 1ZOQA 4KU0D 2AFFA 2FEZA 1J4LA 1UHTA 2BONA 1KHXA 3UOTA 1LGQA 2QVLA 3PO8A 4D9VA 1J4QA 2G1LA 5JEMA 1GXCA 1K2NA 1K3NA 3UNMA 4QCJA 2KFUA 1K2MA 3MDBA 4A4YA 1YGSA 1MJSA 3FM8A 3I6WA 4EGXA 1YJMA 1QWTA 4H87A 1J4PA 5JEKA 1DMZA 2XT9B 5JELA 2W3OA 1G6GA 1U7VB 1FHRA 3VZCA 5C4VA 1R21A 1G88A 1U7FA 3HX1A 5E50A 4JIWD 2JGRA 4WRRA 5JERA 3T5PA 2JPEA 1MR1A 3KT9A 4L02A 5BVIA 3HUEA 2JQLA 1J2FA 1K3JA 2BRFA 3I6UA 1MK2A 3I0MA 1WLNA 4V24A 3VZDA 3UNNA 1WV3A 2JQJA 3VA1A 3UV0A 2EH0A 1U7VA 5DJOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JKD A;  3GQS A;  1YJ5 C;  5A8I A;  1FHQ A;  3HUF A;  1G3G A;  2KKL A;  2JQI A;  3ELV A;  1UJX A;  3UN0 A;  3UMZ A;  4JON A;  2LC1 A;  2KB3 A;  4A0E A;  2A0T A;  1LGP A;  2KB4 A;  2CSW A;  3ELS A;  1J4K A;  1K3Q A;  3I0N A;  1MZK A;  4G2S A;  2FF4 A;  4EJQ A;  3POA A;  3OUN A;  2PIE A;  1QU5 A;  3VPY A;  3VA4 A;  2AFF A;  2FEZ A;  1J4L A;  1UHT A;  3UOT A;  1LGQ A;  3PO8 A;  4D9V A;  1J4Q A;  2G1L A;  1GXC A;  1K2N A;  1K3N A;  3UNM A;  4QCJ A;  2KFU A;  1K2M A;  3MDB A;  3FM8 A;  3I6W A;  4EGX A;  1YJM A;  4H87 A;  1J4P A;  1DMZ A;  2XT9 B;  2W3O A;  1G6G A;  1FHR A;  1R21 A;  3HX1 A;  5E50 A;  2JPE A;  3KT9 A;  3HUE A;  2JQL A;  1K3J A;  2BRF A;  3I6U A;  3I0M A;  1WLN A;  3UNN A;  1WV3 A;  2JQJ A;  3VA1 A;  3UV0 A;  2EH0 A;  1J4O A;  5DJO A; 
#chains in the Genus database with same CATH topology
 2I2A A;  3V80 A;  1U0R A;  3V8R A;  2JKD A;  2P1R A;  2I1W A;  3GQS A;  4R9P A;  5EJI A;  1YJ5 C;  5A8I A;  1FHQ A;  3HUF A;  1G3G A;  5JEO A;  1Z0U A;  5DHS A;  2KKL A;  2I2D A;  2JQI A;  3ELV A;  1UJX A;  1YT5 A;  3PFN A;  3UN0 A;  3DIT A;  4JON A;  4JIV D;  3GMJ A;  3UMZ A;  1J4O A;  1Y3H A;  2LC1 A;  2Q5F A;  2KB3 A;  3DSH A;  4A0E A;  5JEJ A;  2A0T A;  1LGP A;  2XXS A;  1DD1 A;  2QV7 A;  2KB4 A;  1U7F B;  3A77 A;  2CSW A;  5DHT A;  3ELS A;  3VZB A;  3V7U A;  1J4K A;  2I2B A;  3S40 A;  5DHP A;  3V7Y A;  1K3Q A;  3I0N A;  3V8Q A;  4WER A;  1Y3I A;  1MZK A;  4G2S A;  2FF4 A;  4EJQ A;  2I29 A;  3POA A;  3OUN A;  2PIE A;  1QU5 A;  1DEV A;  3VPY A;  1KHU A;  3VA4 A;  1ZOQ A;  4KU0 D;  2AFF A;  2FEZ A;  1J4L A;  1UHT A;  5DHR A;  2BON A;  1KHX A;  3UOT A;  4HAO A;  1LGQ A;  2QVL A;  3PO8 A;  4D9V A;  1J4Q A;  2G1L A;  5EJF A;  5JEM A;  1SUW A;  5EJH A;  1GXC A;  1K2N A;  1K3N A;  3UNM A;  4QCJ A;  2KFU A;  1K2M A;  3MDB A;  4A4Y A;  1Z0Z A;  1YGS A;  1MJS A;  3FM8 A;  1U0T A;  3I6W A;  1YJM A;  4EGX A;  1QWT A;  4H87 A;  1J4P A;  5JEK A;  1DMZ A;  2XT9 B;  5JEL A;  2W3O A;  1G6G A;  1U7V B;  1FHR A;  3V8N A;  3VZC A;  3AFO A;  5C4V A;  1R21 A;  3V8M A;  1G88 A;  1U7F A;  3HX1 A;  5E50 A;  1Z0S A;  4JIW D;  2JGR A;  4WRR A;  3V7W A;  5JER A;  3T5P A;  5DHQ A;  2JPE A;  1MR1 A;  3KT9 A;  4L02 A;  5DHU A;  5BVI A;  3HUE A;  5EJG A;  2JQL A;  1J2F A;  2I2F A;  1K3J A;  3V8P A;  2BRF A;  2AN1 A;  3I6U A;  1MK2 A;  3I0M A;  1WLN A;  4V24 A;  3VZD A;  3UNN A;  2I2C A;  1WV3 A;  2JQJ A;  3VA1 A;  3UV0 A;  4DY6 A;  2EH0 A;  1U7V A;  5DJO A; 
#chains in the Genus database with same CATH homology
 2JKD A;  2P1R A;  3GQS A;  4R9P A;  1YJ5 C;  5A8I A;  1FHQ A;  3HUF A;  1G3G A;  5JEO A;  2KKL A;  2JQI A;  3ELV A;  1UJX A;  3UN0 A;  3UMZ A;  3DIT A;  4JON A;  4JIV D;  3GMJ A;  1J4O A;  2LC1 A;  2KB3 A;  3DSH A;  4A0E A;  5JEJ A;  2A0T A;  1LGP A;  2XXS A;  1DD1 A;  2QV7 A;  2KB4 A;  1U7F B;  3A77 A;  2CSW A;  3ELS A;  3VZB A;  1J4K A;  3S40 A;  1K3Q A;  3I0N A;  4WER A;  1MZK A;  4G2S A;  2FF4 A;  4EJQ A;  3POA A;  3OUN A;  2PIE A;  1QU5 A;  1DEV A;  3VPY A;  1KHU A;  3VA4 A;  1ZOQ A;  4KU0 D;  2AFF A;  2FEZ A;  1J4L A;  1UHT A;  2BON A;  1KHX A;  3UOT A;  1LGQ A;  2QVL A;  3PO8 A;  4D9V A;  1J4Q A;  2G1L A;  5JEM A;  1GXC A;  1K2N A;  1K3N A;  3UNM A;  4QCJ A;  2KFU A;  1K2M A;  3MDB A;  4A4Y A;  1YGS A;  1MJS A;  3FM8 A;  3I6W A;  4EGX A;  1YJM A;  1QWT A;  4H87 A;  1J4P A;  5JEK A;  1DMZ A;  2XT9 B;  5JEL A;  2W3O A;  1G6G A;  1U7V B;  1FHR A;  3VZC A;  5C4V A;  1R21 A;  1G88 A;  1U7F A;  3HX1 A;  5E50 A;  4JIW D;  2JGR A;  4WRR A;  5JER A;  3T5P A;  2JPE A;  1MR1 A;  3KT9 A;  4L02 A;  5BVI A;  3HUE A;  2JQL A;  1J2F A;  1K3J A;  2BRF A;  3I6U A;  1MK2 A;  3I0M A;  1WLN A;  4V24 A;  3VZD A;  3UNN A;  1WV3 A;  2JQJ A;  3VA1 A;  3UV0 A;  2EH0 A;  1U7V A;  5DJO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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