4R1B | Genus

Total Genus 85

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	85
sequence length	331
structure length	282
Chain Sequence	NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIISNTTFLTPVATGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPKLTDYEKIKEGFKNYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 282 atoms

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282 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Cell invasion
source organism	Plasmodium falciparum 3d7
publication title	Structure and Dynamics of Apical Membrane Antigen 1 from Plasmodium falciparum FVO. pubmed doi rcsb
molecule keywords	Apical membrane antigen 1, AMA1
total genus	85
structure length	282
sequence length	331
ec nomenclature
pdb deposition date	2014-08-04

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.50.4.10	Alpha Beta	3-Layer(bba) Sandwich	Hepatocyte Growth Factor	Hepatocyte Growth Factor	4r1bA01

4APLA 1GMNA 1GP9A 1Z40A 4R1CA 2QJ2A 2Z8WA 2LL4M 5I25A 2YILA 3HMSA 2Q8AA 2Y8RA 2J8JA 1YXEA 3MKPA 1GMOA 4R1AA 5COEA 5CSQA 4R19A 4A5TS 2K13X 4APMA 2YIOA 3ZWZA 5CP9A 4R1BA 1NK1A 5CT2A 3SRIA 5CS3A 4UV6A 5CS5A 2Q8BA 5CS9A 2LL3A 1I8NA 1BHTA 5EOKA 2F83A 1HKYA 5CT1A 3HN4A 2QJ4A 5CT3A 3SRJA 2YIPA 2X2ZA 5EODA 1W8KA 1W81A 4Z09A 4UAOA 3SP8A 2J8LA 4Z0EA 4IUAA 2HGFA 3HMRA 3ZLEA 2Z8VA 5CS1A 4Z0DA 4DURA 4Z0FA 3HMTA
chains in the Genus database with same CATH superfamily

4APLA 1GMNA 1GP9A 1Z40A 4R1CA 2QJ2A 2Z8WA 2LL4M 2KL5A 5I25A 2YILA 3HMSA 2Q8AA 2Y8RA 2J8JA 1YXEA 3MKPA 1GMOA 4R1AA 5COEA 5CSQA 4R19A 4YIZA 4DURA 4A5TS 2K13X 4APMA 2YIOA 3ZWZA 5CP9A 4R1BA 1NK1A 5CT2A 3SRIA 5CS3A 4UV6A 5CS5A 2Q8BA 5CS9A 2LL3A 1I8NA 1BHTA 5EOKA 2F83A 1HKYA 5CT1A 3HN4A 2QJ4A 5CT3A 3SRJA 2YIPA 2X2ZA 5EODA 1W8KA 1W81A 4Z09A 4UAOA 3SP8A 2J8LA 4Z0EA 4IUAA 2HGFA 3HMRA 4YIVA 2Z8VA 5CS1A 4Z0DA 3ZLEA 4Z0FA 3HMTA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4APL A;  1GMN A;  1GP9 A;  1Z40 A;  4R1C A;  2QJ2 A;  2Z8W A;  2LL4 M;  5I25 A;  2YIL A;  3HMS A;  2Q8A A;  2Y8R A;  2J8J A;  1YXE A;  3MKP A;  1GMO A;  4R1A A;  5COE A;  5CSQ A;  4R19 A;  4A5T S;  2K13 X;  4APM A;  2YIO A;  3ZWZ A;  5CP9 A;  4R1B A;  1NK1 A;  5CT2 A;  3SRI A;  5CS3 A;  4UV6 A;  5CS5 A;  2Q8B A;  5CS9 A;  2LL3 A;  1I8N A;  1BHT A;  5EOK A;  2F83 A;  1HKY A;  5CT1 A;  3HN4 A;  2QJ4 A;  5CT3 A;  3SRJ A;  2YIP A;  2X2Z A;  5EOD A;  1W8K A;  1W81 A;  4Z09 A;  4UAO A;  3SP8 A;  2J8L A;  4Z0E A;  4IUA A;  2HGF A;  3HMR A;  3ZLE A;  2Z8V A;  5CS1 A;  4Z0D A;  4DUR A;  4Z0F A;  3HMT A; 
#chains in the Genus database with same CATH topology
 4APL A;  1GMN A;  1GP9 A;  1Z40 A;  4R1C A;  2QJ2 A;  2Z8W A;  2LL4 M;  2KL5 A;  5I25 A;  2YIL A;  3HMS A;  2Q8A A;  2Y8R A;  2J8J A;  1YXE A;  3MKP A;  1GMO A;  4R1A A;  5COE A;  5CSQ A;  4R19 A;  4YIZ A;  4DUR A;  4A5T S;  2K13 X;  4APM A;  2YIO A;  3ZWZ A;  5CP9 A;  4R1B A;  1NK1 A;  5CT2 A;  3SRI A;  5CS3 A;  4UV6 A;  5CS5 A;  2Q8B A;  5CS9 A;  2LL3 A;  1I8N A;  1BHT A;  5EOK A;  2F83 A;  1HKY A;  5CT1 A;  3HN4 A;  2QJ4 A;  5CT3 A;  3SRJ A;  2YIP A;  2X2Z A;  5EOD A;  1W8K A;  1W81 A;  4Z09 A;  4UAO A;  3SP8 A;  2J8L A;  4Z0E A;  4IUA A;  2HGF A;  3HMR A;  4YIV A;  2Z8V A;  5CS1 A;  4Z0D A;  3ZLE A;  4Z0F A;  3HMT A; 
#chains in the Genus database with same CATH homology
 4APL A;  1GMN A;  1GP9 A;  1Z40 A;  4R1C A;  2QJ2 A;  2Z8W A;  2LL4 M;  2KL5 A;  5I25 A;  2YIL A;  3HMS A;  2Q8A A;  2Y8R A;  2J8J A;  1YXE A;  3MKP A;  1GMO A;  4R1A A;  5COE A;  5CSQ A;  4R19 A;  4YIZ A;  4DUR A;  4A5T S;  2K13 X;  4APM A;  2YIO A;  3ZWZ A;  5CP9 A;  4R1B A;  1NK1 A;  5CT2 A;  3SRI A;  5CS3 A;  4UV6 A;  5CS5 A;  2Q8B A;  5CS9 A;  2LL3 A;  1I8N A;  1BHT A;  5EOK A;  2F83 A;  1HKY A;  5CT1 A;  3HN4 A;  2QJ4 A;  5CT3 A;  3SRJ A;  2YIP A;  2X2Z A;  5EOD A;  1W8K A;  1W81 A;  4Z09 A;  4UAO A;  3SP8 A;  2J8L A;  4Z0E A;  4IUA A;  2HGF A;  3HMR A;  4YIV A;  2Z8V A;  5CS1 A;  4Z0D A;  3ZLE A;  4Z0F A;  3HMT A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4R1BA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN