4YIVA

Crystal structure of engineered tgama1 lacking the dii loop
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
388
structure length
374
Chain Sequence
GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTTALQCPDSFGACDVQACKRQKTSCVGGQIQSTSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Immune system
source organism Toxoplasma gondii me49
publication title An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
pubmed doi rcsb
molecule keywords Apical membrane antigen AMA1
total genus 101
structure length 374
sequence length 388
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.30 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4yivA01
4YIVA 4YIZA
chains in the Genus database with same CATH superfamily
1W8KA 5EOKA 1GMOA 2Q8AA 2X2ZA 4YIVA 1YXEA 3HMSA 4IUAA 2QJ4A 4YIZA 3SP8A 4UAOA 3SRIA 1BHTA 2LL3A 2HGFA 5COEA 5EODA 2QJ2A 2K13X 2Y8RA 1I8NA 4R1BA 3ZWZA 4Z09A 4APMA 1GP9A 2Q8BA 3ZLEA 2Z8WA 4Z0DA 1HKYA 2F83A 4R19A 5CSQA 5CT3A 4A5TS 4UV6A 5CS9A 3HN4A 3MKPA 5CP9A 1NK1A 5CS3A 4Z0FA 2YILA 2YIPA 2Z8VA 4R1CA 5CS5A 2J8LA 5CT2A 2KL5A 3SRJA 5CT1A 3HMRA 2LL4M 2J8JA 1W81A 4APLA 4R1AA 5CS1A 1GMNA 5I25A 3HMTA 4Z0EA 1Z40A 2YIOA 4DURA
chains in the Genus database with same CATH topology
1W8KA 5EOKA 1GMOA 2Q8AA 2X2ZA 4YIVA 1YXEA 3HMSA 4IUAA 2QJ4A 4YIZA 3SP8A 4UAOA 3SRIA 1BHTA 2LL3A 2HGFA 5COEA 5EODA 2QJ2A 2K13X 2Y8RA 1I8NA 4R1BA 3ZWZA 4Z09A 4APMA 1GP9A 2Q8BA 3ZLEA 2Z8WA 4Z0DA 1HKYA 2F83A 4R19A 5CSQA 5CT3A 4A5TS 4UV6A 5CS9A 3HN4A 3MKPA 5CP9A 1NK1A 5CS3A 4Z0FA 2YILA 2YIPA 2Z8VA 4R1CA 5CS5A 2J8LA 5CT2A 2KL5A 3SRJA 5CT1A 3HMRA 2LL4M 2J8JA 1W81A 4APLA 4R1AA 5CS1A 1GMNA 5I25A 3HMTA 4Z0EA 1Z40A 2YIOA 4DURA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YIV A;  4YIZ A; 
#chains in the Genus database with same CATH topology
 1W8K A;  5EOK A;  1GMO A;  2Q8A A;  2X2Z A;  4YIV A;  1YXE A;  3HMS A;  4IUA A;  2QJ4 A;  4YIZ A;  3SP8 A;  4UAO A;  3SRI A;  1BHT A;  2LL3 A;  2HGF A;  5COE A;  5EOD A;  2QJ2 A;  2K13 X;  2Y8R A;  1I8N A;  4R1B A;  3ZWZ A;  4Z09 A;  4APM A;  1GP9 A;  2Q8B A;  3ZLE A;  2Z8W A;  4Z0D A;  1HKY A;  2F83 A;  4R19 A;  5CSQ A;  5CT3 A;  4A5T S;  4UV6 A;  5CS9 A;  3HN4 A;  3MKP A;  5CP9 A;  1NK1 A;  5CS3 A;  4Z0F A;  2YIL A;  2YIP A;  2Z8V A;  4R1C A;  5CS5 A;  2J8L A;  5CT2 A;  2KL5 A;  3SRJ A;  5CT1 A;  3HMR A;  2LL4 M;  2J8J A;  1W81 A;  4APL A;  4R1A A;  5CS1 A;  1GMN A;  5I25 A;  3HMT A;  4Z0E A;  1Z40 A;  2YIO A;  4DUR A; 
#chains in the Genus database with same CATH homology
 1W8K A;  5EOK A;  1GMO A;  2Q8A A;  2X2Z A;  4YIV A;  1YXE A;  3HMS A;  4IUA A;  2QJ4 A;  4YIZ A;  3SP8 A;  4UAO A;  3SRI A;  1BHT A;  2LL3 A;  2HGF A;  5COE A;  5EOD A;  2QJ2 A;  2K13 X;  2Y8R A;  1I8N A;  4R1B A;  3ZWZ A;  4Z09 A;  4APM A;  1GP9 A;  2Q8B A;  3ZLE A;  2Z8W A;  4Z0D A;  1HKY A;  2F83 A;  4R19 A;  5CSQ A;  5CT3 A;  4A5T S;  4UV6 A;  5CS9 A;  3HN4 A;  3MKP A;  5CP9 A;  1NK1 A;  5CS3 A;  4Z0F A;  2YIL A;  2YIP A;  2Z8V A;  4R1C A;  5CS5 A;  2J8L A;  5CT2 A;  2KL5 A;  3SRJ A;  5CT1 A;  3HMR A;  2LL4 M;  2J8J A;  1W81 A;  4APL A;  4R1A A;  5CS1 A;  1GMN A;  5I25 A;  3HMT A;  4Z0E A;  1Z40 A;  2YIO A;  4DUR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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