4YIVA

Crystal structure of engineered tgama1 lacking the dii loop
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
388
structure length
374
Chain Sequence
GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTTALQCPDSFGACDVQACKRQKTSCVGGQIQSTSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
pubmed doi rcsb
molecule keywords Apical membrane antigen AMA1
molecule tags Immune system
source organism Toxoplasma gondii me49
total genus 101
structure length 374
sequence length 388
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.30 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4yivA01
4YIVA 4YIZA
chains in the Genus database with same CATH superfamily
1Z40A 4R1AA 5CS3A 1HKYA 3HMSA 4Z0FA 5EODA 2LL4M 3ZWZA 1W81A 1W8KA 4R1BA 4Z09A 5CT1A 5CT2A 2Q8AA 4APMA 4R1CA 1BHTA 3HN4A 4Z0EA 4UAOA 2F83A 5CS5A 5EOKA 5I25A 1GP9A 2Z8WA 2J8JA 1GMNA 4DURA 5COEA 2QJ4A 5CS9A 2YILA 3HMTA 3SRIA 1I8NA 2QJ2A 4IUAA 4R19A 3ZLEA 4Z0DA 1NK1A 2HGFA 2K13X 2YIOA 2LL3A 2X2ZA 5CS1A 2Y8RA 5CT3A 5CSQA 3SP8A 3SRJA 1GMOA 2KL5A 4APLA 5CP9A 4YIZA 3HMRA 2YIPA 1YXEA 2Z8VA 3MKPA 4YIVA 2Q8BA 4UV6A 4A5TS 2J8LA
chains in the Genus database with same CATH topology
1Z40A 4R1AA 5CS3A 1HKYA 3HMSA 4Z0FA 5EODA 2LL4M 3ZWZA 1W81A 1W8KA 4R1BA 4Z09A 5CT1A 5CT2A 2Q8AA 4APMA 4R1CA 1BHTA 3HN4A 4Z0EA 4UAOA 2F83A 5CS5A 5EOKA 5I25A 1GP9A 2Z8WA 2J8JA 1GMNA 4DURA 5COEA 2QJ4A 5CS9A 2YILA 3HMTA 3SRIA 1I8NA 2QJ2A 4IUAA 4R19A 3ZLEA 4Z0DA 1NK1A 2HGFA 2K13X 2YIOA 2LL3A 2X2ZA 5CS1A 2Y8RA 5CT3A 5CSQA 3SP8A 3SRJA 1GMOA 2KL5A 4APLA 5CP9A 4YIZA 3HMRA 2YIPA 1YXEA 2Z8VA 3MKPA 4YIVA 2Q8BA 4UV6A 4A5TS 2J8LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YIV A;  4YIZ A; 
#chains in the Genus database with same CATH topology
 1Z40 A;  4R1A A;  5CS3 A;  1HKY A;  3HMS A;  4Z0F A;  5EOD A;  2LL4 M;  3ZWZ A;  1W81 A;  1W8K A;  4R1B A;  4Z09 A;  5CT1 A;  5CT2 A;  2Q8A A;  4APM A;  4R1C A;  1BHT A;  3HN4 A;  4Z0E A;  4UAO A;  2F83 A;  5CS5 A;  5EOK A;  5I25 A;  1GP9 A;  2Z8W A;  2J8J A;  1GMN A;  4DUR A;  5COE A;  2QJ4 A;  5CS9 A;  2YIL A;  3HMT A;  3SRI A;  1I8N A;  2QJ2 A;  4IUA A;  4R19 A;  3ZLE A;  4Z0D A;  1NK1 A;  2HGF A;  2K13 X;  2YIO A;  2LL3 A;  2X2Z A;  5CS1 A;  2Y8R A;  5CT3 A;  5CSQ A;  3SP8 A;  3SRJ A;  1GMO A;  2KL5 A;  4APL A;  5CP9 A;  4YIZ A;  3HMR A;  2YIP A;  1YXE A;  2Z8V A;  3MKP A;  4YIV A;  2Q8B A;  4UV6 A;  4A5T S;  2J8L A; 
#chains in the Genus database with same CATH homology
 1Z40 A;  4R1A A;  5CS3 A;  1HKY A;  3HMS A;  4Z0F A;  5EOD A;  2LL4 M;  3ZWZ A;  1W81 A;  1W8K A;  4R1B A;  4Z09 A;  5CT1 A;  5CT2 A;  2Q8A A;  4APM A;  4R1C A;  1BHT A;  3HN4 A;  4Z0E A;  4UAO A;  2F83 A;  5CS5 A;  5EOK A;  5I25 A;  1GP9 A;  2Z8W A;  2J8J A;  1GMN A;  4DUR A;  5COE A;  2QJ4 A;  5CS9 A;  2YIL A;  3HMT A;  3SRI A;  1I8N A;  2QJ2 A;  4IUA A;  4R19 A;  3ZLE A;  4Z0D A;  1NK1 A;  2HGF A;  2K13 X;  2YIO A;  2LL3 A;  2X2Z A;  5CS1 A;  2Y8R A;  5CT3 A;  5CSQ A;  3SP8 A;  3SRJ A;  1GMO A;  2KL5 A;  4APL A;  5CP9 A;  4YIZ A;  3HMR A;  2YIP A;  1YXE A;  2Z8V A;  3MKP A;  4YIV A;  2Q8B A;  4UV6 A;  4A5T S;  2J8L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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