4Z09A

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [thr2040ala] peptide
Total Genus 78

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
O6 (1-13)TVIII2 (225-228)EMPTYTI5 (208-211)O2 (149-302)S2 (140-144)TI2 (164-167)TI1 (108-111)AH1 (119-123)S1 (133-137)TIV4 (169-179)TIV2 (136-139)AH3 (213-222)TI4 (205-208)S3 (151-152)S4 (154-158)TII1 (151-154)TIV10 (257-275)TIV6 (190-193)TVIII3 (250-253)TIV5 (186-189)AH2 (195-202)TIV9 (241-244)TI3 (202-205)TIV7 (206-209)S6 (238-241)TIV8 (227-230)S7 (246-249)TVIII1 (127-130)TIV3 (158-164)TIV1 (126-129)3H1 (112-117)Updating...
connected with : NaN
molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
total genus 78
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z09A01
1BHTA 2Q8AA 4DURA 2X2ZA 2LL4M 1GP9A 1HKYA 1NK1A 3ZWZA 3MKPA 5CS1A 3SRJA 4APLA 1YXEA 1Z40A 3HMSA 3SP8A 2Z8VA 5CS9A 4APMA 5CT2A 4R1CA 1GMNA 5CS3A 2F83A 2K13X 2Q8BA 3ZLEA 4A5TS 4R1BA 4Z0FA 5EODA 1GMOA 5CP9A 3HMTA 4R19A 3HN4A 3HMRA 5EOKA 2QJ2A 2J8JA 5CSQA 4Z0DA 5I25A 4UV6A 5CT3A 5CT1A 1I8NA 1W81A 2Y8RA 2YIPA 2Z8WA 4R1AA 4Z0EA 3SRIA 2YIOA 2LL3A 2QJ4A 2YILA 4UAOA 4IUAA 5CS5A 4Z09A 5COEA 2HGFA 1W8KA 2J8LA
chains in the Genus database with same CATH superfamily
1BHTA 2Q8AA 4DURA 2X2ZA 2KL5A 2LL4M 1GP9A 1HKYA 1NK1A 3ZWZA 3MKPA 5CS1A 3SRJA 4APLA 1YXEA 1Z40A 3HMSA 4YIVA 3SP8A 2Z8VA 5CS9A 4APMA 5CT2A 4R1CA 4YIZA 1GMNA 5CS3A 2F83A 2K13X 2Q8BA 3ZLEA 4A5TS 4R1BA 4Z0FA 5EODA 1GMOA 5CP9A 3HMTA 4R19A 3HN4A 3HMRA 5EOKA 2QJ2A 2J8JA 5CSQA 4Z0DA 5I25A 4UV6A 5CT3A 5CT1A 1I8NA 1W81A 2Y8RA 2YIPA 2Z8WA 4R1AA 4Z0EA 3SRIA 2YIOA 2LL3A 2QJ4A 2YILA 4UAOA 4IUAA 5CS5A 4Z09A 5COEA 2HGFA 1W8KA 2J8LA
chains in the Genus database with same CATH topology
1BHTA 2Q8AA 4DURA 2X2ZA 2KL5A 2LL4M 1GP9A 1HKYA 1NK1A 3ZWZA 3MKPA 5CS1A 3SRJA 4APLA 1YXEA 1Z40A 3HMSA 4YIVA 3SP8A 2Z8VA 5CS9A 4APMA 5CT2A 4R1CA 4YIZA 1GMNA 5CS3A 2F83A 2K13X 2Q8BA 3ZLEA 4A5TS 4R1BA 4Z0FA 5EODA 1GMOA 5CP9A 3HMTA 4R19A 3HN4A 3HMRA 5EOKA 2QJ2A 2J8JA 5CSQA 4Z0DA 5I25A 4UV6A 5CT3A 5CT1A 1I8NA 1W81A 2Y8RA 2YIPA 2Z8WA 4R1AA 4Z0EA 3SRIA 2YIOA 2LL3A 2QJ4A 2YILA 4UAOA 4IUAA 5CS5A 4Z09A 5COEA 2HGFA 1W8KA 2J8LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BHT A;  2Q8A A;  4DUR A;  2X2Z A;  2LL4 M;  1GP9 A;  1HKY A;  1NK1 A;  3ZWZ A;  3MKP A;  5CS1 A;  3SRJ A;  4APL A;  1YXE A;  1Z40 A;  3HMS A;  3SP8 A;  2Z8V A;  5CS9 A;  4APM A;  5CT2 A;  4R1C A;  1GMN A;  5CS3 A;  2F83 A;  2K13 X;  2Q8B A;  3ZLE A;  4A5T S;  4R1B A;  4Z0F A;  5EOD A;  1GMO A;  5CP9 A;  3HMT A;  4R19 A;  3HN4 A;  3HMR A;  5EOK A;  2QJ2 A;  2J8J A;  5CSQ A;  4Z0D A;  5I25 A;  4UV6 A;  5CT3 A;  5CT1 A;  1I8N A;  1W81 A;  2Y8R A;  2YIP A;  2Z8W A;  4R1A A;  4Z0E A;  3SRI A;  2YIO A;  2LL3 A;  2QJ4 A;  2YIL A;  4UAO A;  4IUA A;  5CS5 A;  4Z09 A;  5COE A;  2HGF A;  1W8K A;  2J8L A; 
#chains in the Genus database with same CATH topology
 1BHT A;  2Q8A A;  4DUR A;  2X2Z A;  2KL5 A;  2LL4 M;  1GP9 A;  1HKY A;  1NK1 A;  3ZWZ A;  3MKP A;  5CS1 A;  3SRJ A;  4APL A;  1YXE A;  1Z40 A;  3HMS A;  4YIV A;  3SP8 A;  2Z8V A;  5CS9 A;  4APM A;  5CT2 A;  4R1C A;  4YIZ A;  1GMN A;  5CS3 A;  2F83 A;  2K13 X;  2Q8B A;  3ZLE A;  4A5T S;  4R1B A;  4Z0F A;  5EOD A;  1GMO A;  5CP9 A;  3HMT A;  4R19 A;  3HN4 A;  3HMR A;  5EOK A;  2QJ2 A;  2J8J A;  5CSQ A;  4Z0D A;  5I25 A;  4UV6 A;  5CT3 A;  5CT1 A;  1I8N A;  1W81 A;  2Y8R A;  2YIP A;  2Z8W A;  4R1A A;  4Z0E A;  3SRI A;  2YIO A;  2LL3 A;  2QJ4 A;  2YIL A;  4UAO A;  4IUA A;  5CS5 A;  4Z09 A;  5COE A;  2HGF A;  1W8K A;  2J8L A; 
#chains in the Genus database with same CATH homology
 1BHT A;  2Q8A A;  4DUR A;  2X2Z A;  2KL5 A;  2LL4 M;  1GP9 A;  1HKY A;  1NK1 A;  3ZWZ A;  3MKP A;  5CS1 A;  3SRJ A;  4APL A;  1YXE A;  1Z40 A;  3HMS A;  4YIV A;  3SP8 A;  2Z8V A;  5CS9 A;  4APM A;  5CT2 A;  4R1C A;  4YIZ A;  1GMN A;  5CS3 A;  2F83 A;  2K13 X;  2Q8B A;  3ZLE A;  4A5T S;  4R1B A;  4Z0F A;  5EOD A;  1GMO A;  5CP9 A;  3HMT A;  4R19 A;  3HN4 A;  3HMR A;  5EOK A;  2QJ2 A;  2J8J A;  5CSQ A;  4Z0D A;  5I25 A;  4UV6 A;  5CT3 A;  5CT1 A;  1I8N A;  1W81 A;  2Y8R A;  2YIP A;  2Z8W A;  4R1A A;  4Z0E A;  3SRI A;  2YIO A;  2LL3 A;  2QJ4 A;  2YIL A;  4UAO A;  4IUA A;  5CS5 A;  4Z09 A;  5COE A;  2HGF A;  1W8K A;  2J8L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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