4Z09A

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [thr2040ala] peptide
Total Genus 78
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
78
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
molecule keywords Apical membrane antigen 1
total genus 78
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z09A01
2LL3A 2J8JA 3ZLEA 3MKPA 5EODA 4R1BA 1YXEA 2F83A 2QJ4A 5I25A 5CSQA 3HN4A 5CT1A 4Z0DA 4UAOA 4UV6A 2LL4M 1Z40A 1I8NA 2Y8RA 4R1CA 2K13X 5CS9A 4Z09A 2Q8BA 1HKYA 2YIPA 4Z0FA 1GP9A 1GMOA 5CS3A 3HMTA 4R19A 3HMRA 4A5TS 2YILA 2QJ2A 2J8LA 5EOKA 2Z8WA 2YIOA 1NK1A 4APLA 3SRIA 5CS5A 4APMA 3HMSA 3SRJA 1W8KA 4DURA 4R1AA 5CT2A 2HGFA 3ZWZA 5CT3A 5CP9A 2Q8AA 5CS1A 1BHTA 1GMNA 1W81A 4Z0EA 2Z8VA 4IUAA 2X2ZA 3SP8A 5COEA
chains in the Genus database with same CATH superfamily
2LL3A 2J8JA 3ZLEA 3MKPA 5EODA 4R1BA 1YXEA 2F83A 2QJ4A 4YIVA 5I25A 5CSQA 3HN4A 5CT1A 4Z0DA 4UAOA 4UV6A 2LL4M 1Z40A 1I8NA 2Y8RA 4R1CA 2K13X 5CS9A 4Z09A 2Q8BA 1HKYA 2YIPA 4Z0FA 1GP9A 1GMOA 5CS3A 3HMTA 4R19A 3HMRA 4YIZA 4A5TS 2YILA 2QJ2A 2J8LA 5EOKA 2Z8WA 2YIOA 1NK1A 4APLA 3SRIA 5CS5A 4APMA 3HMSA 3SRJA 1W8KA 4DURA 2KL5A 4R1AA 5CT2A 2HGFA 3ZWZA 5CT3A 5CP9A 2Q8AA 5CS1A 1BHTA 1GMNA 1W81A 4Z0EA 2Z8VA 4IUAA 2X2ZA 3SP8A 5COEA
chains in the Genus database with same CATH topology
2LL3A 2J8JA 3ZLEA 3MKPA 5EODA 4R1BA 1YXEA 2F83A 2QJ4A 4YIVA 5I25A 5CSQA 3HN4A 5CT1A 4Z0DA 4UAOA 4UV6A 2LL4M 1Z40A 1I8NA 2Y8RA 4R1CA 2K13X 5CS9A 4Z09A 2Q8BA 1HKYA 2YIPA 4Z0FA 1GP9A 1GMOA 5CS3A 3HMTA 4R19A 3HMRA 4YIZA 4A5TS 2YILA 2QJ2A 2J8LA 5EOKA 2Z8WA 2YIOA 1NK1A 4APLA 3SRIA 5CS5A 4APMA 3HMSA 3SRJA 1W8KA 4DURA 2KL5A 4R1AA 5CT2A 2HGFA 3ZWZA 5CT3A 5CP9A 2Q8AA 5CS1A 1BHTA 1GMNA 1W81A 4Z0EA 2Z8VA 4IUAA 2X2ZA 3SP8A 5COEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2LL3 A;  2J8J A;  3ZLE A;  3MKP A;  5EOD A;  4R1B A;  1YXE A;  2F83 A;  2QJ4 A;  5I25 A;  5CSQ A;  3HN4 A;  5CT1 A;  4Z0D A;  4UAO A;  4UV6 A;  2LL4 M;  1Z40 A;  1I8N A;  2Y8R A;  4R1C A;  2K13 X;  5CS9 A;  4Z09 A;  2Q8B A;  1HKY A;  2YIP A;  4Z0F A;  1GP9 A;  1GMO A;  5CS3 A;  3HMT A;  4R19 A;  3HMR A;  4A5T S;  2YIL A;  2QJ2 A;  2J8L A;  5EOK A;  2Z8W A;  2YIO A;  1NK1 A;  4APL A;  3SRI A;  5CS5 A;  4APM A;  3HMS A;  3SRJ A;  1W8K A;  4DUR A;  4R1A A;  5CT2 A;  2HGF A;  3ZWZ A;  5CT3 A;  5CP9 A;  2Q8A A;  5CS1 A;  1BHT A;  1GMN A;  1W81 A;  4Z0E A;  2Z8V A;  4IUA A;  2X2Z A;  3SP8 A;  5COE A; 
#chains in the Genus database with same CATH topology
 2LL3 A;  2J8J A;  3ZLE A;  3MKP A;  5EOD A;  4R1B A;  1YXE A;  2F83 A;  2QJ4 A;  4YIV A;  5I25 A;  5CSQ A;  3HN4 A;  5CT1 A;  4Z0D A;  4UAO A;  4UV6 A;  2LL4 M;  1Z40 A;  1I8N A;  2Y8R A;  4R1C A;  2K13 X;  5CS9 A;  4Z09 A;  2Q8B A;  1HKY A;  2YIP A;  4Z0F A;  1GP9 A;  1GMO A;  5CS3 A;  3HMT A;  4R19 A;  3HMR A;  4YIZ A;  4A5T S;  2YIL A;  2QJ2 A;  2J8L A;  5EOK A;  2Z8W A;  2YIO A;  1NK1 A;  4APL A;  3SRI A;  5CS5 A;  4APM A;  3HMS A;  3SRJ A;  1W8K A;  4DUR A;  2KL5 A;  4R1A A;  5CT2 A;  2HGF A;  3ZWZ A;  5CT3 A;  5CP9 A;  2Q8A A;  5CS1 A;  1BHT A;  1GMN A;  1W81 A;  4Z0E A;  2Z8V A;  4IUA A;  2X2Z A;  3SP8 A;  5COE A; 
#chains in the Genus database with same CATH homology
 2LL3 A;  2J8J A;  3ZLE A;  3MKP A;  5EOD A;  4R1B A;  1YXE A;  2F83 A;  2QJ4 A;  4YIV A;  5I25 A;  5CSQ A;  3HN4 A;  5CT1 A;  4Z0D A;  4UAO A;  4UV6 A;  2LL4 M;  1Z40 A;  1I8N A;  2Y8R A;  4R1C A;  2K13 X;  5CS9 A;  4Z09 A;  2Q8B A;  1HKY A;  2YIP A;  4Z0F A;  1GP9 A;  1GMO A;  5CS3 A;  3HMT A;  4R19 A;  3HMR A;  4YIZ A;  4A5T S;  2YIL A;  2QJ2 A;  2J8L A;  5EOK A;  2Z8W A;  2YIO A;  1NK1 A;  4APL A;  3SRI A;  5CS5 A;  4APM A;  3HMS A;  3SRJ A;  1W8K A;  4DUR A;  2KL5 A;  4R1A A;  5CT2 A;  2HGF A;  3ZWZ A;  5CT3 A;  5CP9 A;  2Q8A A;  5CS1 A;  1BHT A;  1GMN A;  1W81 A;  4Z0E A;  2Z8V A;  4IUA A;  2X2Z A;  3SP8 A;  5COE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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