4Z0DA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trp] peptide
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
331
structure length
273
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 74
structure length 273
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0dA01
5CS3A 2LL3A 3HMTA 4R1AA 3SRIA 1I8NA 2Q8AA 1HKYA 4Z09A 5CS9A 5CT2A 5CSQA 3SP8A 3MKPA 5COEA 2Q8BA 4R1CA 5CT1A 2HGFA 1W81A 2K13X 2YIPA 2YIOA 1GP9A 4APMA 2J8JA 2Z8VA 4Z0DA 2QJ4A 1W8KA 3ZWZA 5I25A 1BHTA 2J8LA 3HMRA 4A5TS 1YXEA 5EOKA 2Z8WA 3HMSA 1GMNA 4UAOA 3ZLEA 4APLA 2Y8RA 4UV6A 2QJ2A 4DURA 5CS1A 1NK1A 3HN4A 4IUAA 5CT3A 3SRJA 2YILA 4R19A 1Z40A 5CS5A 4Z0FA 1GMOA 5EODA 4Z0EA 2X2ZA 5CP9A 4R1BA 2F83A 2LL4M
chains in the Genus database with same CATH superfamily
5CS3A 2LL3A 3HMTA 4R1AA 3SRIA 1I8NA 2Q8AA 5CT1A 4Z09A 1HKYA 5CS9A 5CT2A 5CSQA 3SP8A 2KL5A 3MKPA 5COEA 4R1CA 2Q8BA 2HGFA 1W81A 2K13X 2YIPA 2YIOA 1GP9A 4APMA 2J8JA 2Z8VA 4Z0DA 2QJ4A 1W8KA 3ZWZA 5I25A 1BHTA 4YIZA 2J8LA 3HMRA 4A5TS 1YXEA 5EOKA 2Z8WA 3HMSA 1GMNA 4UAOA 3ZLEA 4APLA 2Y8RA 4UV6A 2QJ2A 4DURA 5CS1A 1NK1A 3HN4A 4IUAA 5CT3A 3SRJA 2YILA 4R19A 4YIVA 1Z40A 5CS5A 4Z0FA 1GMOA 5EODA 4Z0EA 2X2ZA 5CP9A 4R1BA 2F83A 2LL4M
chains in the Genus database with same CATH topology
5CS3A 2LL3A 3HMTA 4R1AA 3SRIA 1I8NA 2Q8AA 5CT1A 4Z09A 1HKYA 5CS9A 5CT2A 5CSQA 3SP8A 2KL5A 3MKPA 5COEA 4R1CA 2Q8BA 2HGFA 1W81A 2K13X 2YIPA 2YIOA 1GP9A 4APMA 2J8JA 2Z8VA 4Z0DA 2QJ4A 1W8KA 3ZWZA 5I25A 1BHTA 4YIZA 2J8LA 3HMRA 4A5TS 1YXEA 5EOKA 2Z8WA 3HMSA 1GMNA 4UAOA 3ZLEA 4APLA 2Y8RA 4UV6A 2QJ2A 4DURA 5CS1A 1NK1A 3HN4A 4IUAA 5CT3A 3SRJA 2YILA 4R19A 4YIVA 1Z40A 5CS5A 4Z0FA 1GMOA 5EODA 4Z0EA 2X2ZA 5CP9A 4R1BA 2F83A 2LL4M
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CS3 A;  2LL3 A;  3HMT A;  4R1A A;  3SRI A;  1I8N A;  2Q8A A;  1HKY A;  4Z09 A;  5CS9 A;  5CT2 A;  5CSQ A;  3SP8 A;  3MKP A;  5COE A;  2Q8B A;  4R1C A;  5CT1 A;  2HGF A;  1W81 A;  2K13 X;  2YIP A;  2YIO A;  1GP9 A;  4APM A;  2J8J A;  2Z8V A;  4Z0D A;  2QJ4 A;  1W8K A;  3ZWZ A;  5I25 A;  1BHT A;  2J8L A;  3HMR A;  4A5T S;  1YXE A;  5EOK A;  2Z8W A;  3HMS A;  1GMN A;  4UAO A;  3ZLE A;  4APL A;  2Y8R A;  4UV6 A;  2QJ2 A;  4DUR A;  5CS1 A;  1NK1 A;  3HN4 A;  4IUA A;  5CT3 A;  3SRJ A;  2YIL A;  4R19 A;  1Z40 A;  5CS5 A;  4Z0F A;  1GMO A;  5EOD A;  4Z0E A;  2X2Z A;  5CP9 A;  4R1B A;  2F83 A;  2LL4 M; 
#chains in the Genus database with same CATH topology
 5CS3 A;  2LL3 A;  3HMT A;  4R1A A;  3SRI A;  1I8N A;  2Q8A A;  5CT1 A;  4Z09 A;  1HKY A;  5CS9 A;  5CT2 A;  5CSQ A;  3SP8 A;  2KL5 A;  3MKP A;  5COE A;  4R1C A;  2Q8B A;  2HGF A;  1W81 A;  2K13 X;  2YIP A;  2YIO A;  1GP9 A;  4APM A;  2J8J A;  2Z8V A;  4Z0D A;  2QJ4 A;  1W8K A;  3ZWZ A;  5I25 A;  1BHT A;  4YIZ A;  2J8L A;  3HMR A;  4A5T S;  1YXE A;  5EOK A;  2Z8W A;  3HMS A;  1GMN A;  4UAO A;  3ZLE A;  4APL A;  2Y8R A;  4UV6 A;  2QJ2 A;  4DUR A;  5CS1 A;  1NK1 A;  3HN4 A;  4IUA A;  5CT3 A;  3SRJ A;  2YIL A;  4R19 A;  4YIV A;  1Z40 A;  5CS5 A;  4Z0F A;  1GMO A;  5EOD A;  4Z0E A;  2X2Z A;  5CP9 A;  4R1B A;  2F83 A;  2LL4 M; 
#chains in the Genus database with same CATH homology
 5CS3 A;  2LL3 A;  3HMT A;  4R1A A;  3SRI A;  1I8N A;  2Q8A A;  5CT1 A;  4Z09 A;  1HKY A;  5CS9 A;  5CT2 A;  5CSQ A;  3SP8 A;  2KL5 A;  3MKP A;  5COE A;  4R1C A;  2Q8B A;  2HGF A;  1W81 A;  2K13 X;  2YIP A;  2YIO A;  1GP9 A;  4APM A;  2J8J A;  2Z8V A;  4Z0D A;  2QJ4 A;  1W8K A;  3ZWZ A;  5I25 A;  1BHT A;  4YIZ A;  2J8L A;  3HMR A;  4A5T S;  1YXE A;  5EOK A;  2Z8W A;  3HMS A;  1GMN A;  4UAO A;  3ZLE A;  4APL A;  2Y8R A;  4UV6 A;  2QJ2 A;  4DUR A;  5CS1 A;  1NK1 A;  3HN4 A;  4IUA A;  5CT3 A;  3SRJ A;  2YIL A;  4R19 A;  4YIV A;  1Z40 A;  5CS5 A;  4Z0F A;  1GMO A;  5EOD A;  4Z0E A;  2X2Z A;  5CP9 A;  4R1B A;  2F83 A;  2LL4 M; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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