4Z0DA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trp] peptide
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
331
structure length
273
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIETTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNDKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
total genus 74
structure length 273
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0dA01
2F83A 2J8LA 1NK1A 3ZLEA 1GMOA 4Z0DA 4Z0FA 2Z8WA 2J8JA 4R1AA 5EODA 1HKYA 4DURA 3MKPA 4R1CA 2Q8BA 2YILA 3SRIA 5CP9A 2LL4M 2X2ZA 5CSQA 2QJ2A 1I8NA 2YIOA 2Y8RA 4UAOA 5CS1A 2YIPA 5COEA 3SP8A 5EOKA 1W81A 4Z09A 4A5TS 3HMTA 2QJ4A 4IUAA 5CS3A 1YXEA 5CT3A 5I25A 5CS9A 2LL3A 2K13X 2Q8AA 1BHTA 5CT2A 4APMA 4Z0EA 1W8KA 3HMSA 3ZWZA 5CS5A 3SRJA 1GP9A 4UV6A 4APLA 1GMNA 1Z40A 2HGFA 3HN4A 2Z8VA 4R19A 3HMRA 5CT1A 4R1BA
chains in the Genus database with same CATH superfamily
2F83A 2J8LA 1NK1A 3ZLEA 1GMOA 4Z0DA 4Z0FA 2Z8WA 2J8JA 4R1AA 5EODA 1HKYA 4DURA 3MKPA 4R1CA 2Q8BA 2YILA 3SRIA 5CP9A 2LL4M 2X2ZA 5CSQA 2QJ2A 1I8NA 2YIOA 2Y8RA 4UAOA 5CS1A 2YIPA 5COEA 3SP8A 4YIVA 5EOKA 1W81A 4Z09A 4A5TS 3HMTA 2QJ4A 4IUAA 5CS3A 1YXEA 5CT3A 5I25A 5CS9A 2LL3A 2K13X 2Q8AA 1BHTA 5CT2A 4APMA 4Z0EA 1W8KA 3HMSA 4YIZA 3ZWZA 5CS5A 3SRJA 1GP9A 4UV6A 4APLA 1GMNA 1Z40A 2HGFA 2KL5A 2Z8VA 3HN4A 3HMRA 4R19A 4R1BA 5CT1A
chains in the Genus database with same CATH topology
2F83A 2J8LA 1NK1A 3ZLEA 1GMOA 4Z0DA 4Z0FA 2Z8WA 2J8JA 4R1AA 5EODA 1HKYA 4DURA 3MKPA 4R1CA 2Q8BA 2YILA 3SRIA 5CP9A 2LL4M 2X2ZA 5CSQA 2QJ2A 1I8NA 2YIOA 2Y8RA 4UAOA 5CS1A 2YIPA 5COEA 3SP8A 4YIVA 5EOKA 1W81A 4Z09A 4A5TS 3HMTA 2QJ4A 4IUAA 5CS3A 1YXEA 5CT3A 5I25A 5CS9A 2LL3A 2K13X 2Q8AA 1BHTA 5CT2A 4APMA 4Z0EA 1W8KA 3HMSA 4YIZA 3ZWZA 5CS5A 3SRJA 1GP9A 4UV6A 4APLA 1GMNA 1Z40A 2HGFA 2KL5A 2Z8VA 3HN4A 3HMRA 4R19A 4R1BA 5CT1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F83 A;  2J8L A;  1NK1 A;  3ZLE A;  1GMO A;  4Z0D A;  4Z0F A;  2Z8W A;  2J8J A;  4R1A A;  5EOD A;  1HKY A;  4DUR A;  3MKP A;  4R1C A;  2Q8B A;  2YIL A;  3SRI A;  5CP9 A;  2LL4 M;  2X2Z A;  5CSQ A;  2QJ2 A;  1I8N A;  2YIO A;  2Y8R A;  4UAO A;  5CS1 A;  2YIP A;  5COE A;  3SP8 A;  5EOK A;  1W81 A;  4Z09 A;  4A5T S;  3HMT A;  2QJ4 A;  4IUA A;  5CS3 A;  1YXE A;  5CT3 A;  5I25 A;  5CS9 A;  2LL3 A;  2K13 X;  2Q8A A;  1BHT A;  5CT2 A;  4APM A;  4Z0E A;  1W8K A;  3HMS A;  3ZWZ A;  5CS5 A;  3SRJ A;  1GP9 A;  4UV6 A;  4APL A;  1GMN A;  1Z40 A;  2HGF A;  3HN4 A;  2Z8V A;  4R19 A;  3HMR A;  5CT1 A;  4R1B A; 
#chains in the Genus database with same CATH topology
 2F83 A;  2J8L A;  1NK1 A;  3ZLE A;  1GMO A;  4Z0D A;  4Z0F A;  2Z8W A;  2J8J A;  4R1A A;  5EOD A;  1HKY A;  4DUR A;  3MKP A;  4R1C A;  2Q8B A;  2YIL A;  3SRI A;  5CP9 A;  2LL4 M;  2X2Z A;  5CSQ A;  2QJ2 A;  1I8N A;  2YIO A;  2Y8R A;  4UAO A;  5CS1 A;  2YIP A;  5COE A;  3SP8 A;  4YIV A;  5EOK A;  1W81 A;  4Z09 A;  4A5T S;  3HMT A;  2QJ4 A;  4IUA A;  5CS3 A;  1YXE A;  5CT3 A;  5I25 A;  5CS9 A;  2LL3 A;  2K13 X;  2Q8A A;  1BHT A;  5CT2 A;  4APM A;  4Z0E A;  1W8K A;  3HMS A;  4YIZ A;  3ZWZ A;  5CS5 A;  3SRJ A;  1GP9 A;  4UV6 A;  4APL A;  1GMN A;  1Z40 A;  2HGF A;  2KL5 A;  2Z8V A;  3HN4 A;  3HMR A;  4R19 A;  4R1B A;  5CT1 A; 
#chains in the Genus database with same CATH homology
 2F83 A;  2J8L A;  1NK1 A;  3ZLE A;  1GMO A;  4Z0D A;  4Z0F A;  2Z8W A;  2J8J A;  4R1A A;  5EOD A;  1HKY A;  4DUR A;  3MKP A;  4R1C A;  2Q8B A;  2YIL A;  3SRI A;  5CP9 A;  2LL4 M;  2X2Z A;  5CSQ A;  2QJ2 A;  1I8N A;  2YIO A;  2Y8R A;  4UAO A;  5CS1 A;  2YIP A;  5COE A;  3SP8 A;  4YIV A;  5EOK A;  1W81 A;  4Z09 A;  4A5T S;  3HMT A;  2QJ4 A;  4IUA A;  5CS3 A;  1YXE A;  5CT3 A;  5I25 A;  5CS9 A;  2LL3 A;  2K13 X;  2Q8A A;  1BHT A;  5CT2 A;  4APM A;  4Z0E A;  1W8K A;  3HMS A;  4YIZ A;  3ZWZ A;  5CS5 A;  3SRJ A;  1GP9 A;  4UV6 A;  4APL A;  1GMN A;  1Z40 A;  2HGF A;  2KL5 A;  2Z8V A;  3HN4 A;  3HMR A;  4R19 A;  4R1B A;  5CT1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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