4Z0EA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trn] peptide
Total Genus 77
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVGTQYRLPSGKCPVFGKGIIIETTFLKPVAKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNGFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 77
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0eA01
2Z8WA 2F83A 5COEA 2Q8AA 1I8NA 1NK1A 4DURA 5CS9A 2J8JA 4Z0DA 3MKPA 2Q8BA 3HN4A 5CT2A 5CT3A 5CS3A 4APMA 1GP9A 4APLA 5CS1A 3SRJA 2YIPA 4Z09A 3SP8A 4R1AA 1W8KA 3ZLEA 1HKYA 2LL3A 2LL4M 2K13X 1BHTA 1Z40A 2X2ZA 2QJ2A 4A5TS 4R1BA 4UV6A 5CSQA 2Z8VA 5EOKA 2Y8RA 4Z0EA 5CS5A 5EODA 4IUAA 4Z0FA 1YXEA 3SRIA 1W81A 3ZWZA 2QJ4A 3HMSA 2YIOA 4R19A 4R1CA 3HMRA 5CT1A 2HGFA 2J8LA 3HMTA 5CP9A 4UAOA 5I25A 2YILA 1GMOA 1GMNA
chains in the Genus database with same CATH superfamily
2Z8WA 2F83A 5COEA 2Q8AA 1I8NA 1NK1A 4DURA 5CS9A 2J8JA 4Z0DA 3MKPA 2KL5A 2Q8BA 3HN4A 5CT2A 5CT3A 5CS3A 4YIVA 4APMA 1GP9A 4APLA 4YIZA 5CS1A 3SRJA 2YIPA 4Z09A 3SP8A 4R1AA 1W8KA 3ZLEA 1HKYA 2LL3A 2LL4M 2K13X 1BHTA 1Z40A 2X2ZA 2QJ2A 4A5TS 4R1BA 4UV6A 5CSQA 2Z8VA 5EOKA 2Y8RA 4Z0EA 5CS5A 5EODA 4IUAA 4Z0FA 1YXEA 3SRIA 1W81A 3ZWZA 2QJ4A 3HMSA 2YIOA 4R19A 4R1CA 3HMRA 5CT1A 2HGFA 2J8LA 3HMTA 5CP9A 4UAOA 5I25A 2YILA 1GMOA 1GMNA
chains in the Genus database with same CATH topology
2Z8WA 2F83A 5COEA 2Q8AA 1I8NA 1NK1A 4DURA 5CS9A 2J8JA 4Z0DA 3MKPA 2KL5A 2Q8BA 3HN4A 5CT2A 5CT3A 5CS3A 4YIVA 4APMA 1GP9A 4APLA 4YIZA 5CS1A 3SRJA 2YIPA 4Z09A 3SP8A 4R1AA 1W8KA 3ZLEA 1HKYA 2LL3A 2LL4M 2K13X 1BHTA 1Z40A 2X2ZA 2QJ2A 4A5TS 4R1BA 4UV6A 5CSQA 2Z8VA 5EOKA 2Y8RA 4Z0EA 5CS5A 5EODA 4IUAA 4Z0FA 1YXEA 3SRIA 1W81A 3ZWZA 2QJ4A 3HMSA 2YIOA 4R19A 4R1CA 3HMRA 5CT1A 2HGFA 2J8LA 3HMTA 5CP9A 4UAOA 5I25A 2YILA 1GMOA 1GMNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z8W A;  2F83 A;  5COE A;  2Q8A A;  1I8N A;  1NK1 A;  4DUR A;  5CS9 A;  2J8J A;  4Z0D A;  3MKP A;  2Q8B A;  3HN4 A;  5CT2 A;  5CT3 A;  5CS3 A;  4APM A;  1GP9 A;  4APL A;  5CS1 A;  3SRJ A;  2YIP A;  4Z09 A;  3SP8 A;  4R1A A;  1W8K A;  3ZLE A;  1HKY A;  2LL3 A;  2LL4 M;  2K13 X;  1BHT A;  1Z40 A;  2X2Z A;  2QJ2 A;  4A5T S;  4R1B A;  4UV6 A;  5CSQ A;  2Z8V A;  5EOK A;  2Y8R A;  4Z0E A;  5CS5 A;  5EOD A;  4IUA A;  4Z0F A;  1YXE A;  3SRI A;  1W81 A;  3ZWZ A;  2QJ4 A;  3HMS A;  2YIO A;  4R19 A;  4R1C A;  3HMR A;  5CT1 A;  2HGF A;  2J8L A;  3HMT A;  5CP9 A;  4UAO A;  5I25 A;  2YIL A;  1GMO A;  1GMN A; 
#chains in the Genus database with same CATH topology
 2Z8W A;  2F83 A;  5COE A;  2Q8A A;  1I8N A;  1NK1 A;  4DUR A;  5CS9 A;  2J8J A;  4Z0D A;  3MKP A;  2KL5 A;  2Q8B A;  3HN4 A;  5CT2 A;  5CT3 A;  5CS3 A;  4YIV A;  4APM A;  1GP9 A;  4APL A;  4YIZ A;  5CS1 A;  3SRJ A;  2YIP A;  4Z09 A;  3SP8 A;  4R1A A;  1W8K A;  3ZLE A;  1HKY A;  2LL3 A;  2LL4 M;  2K13 X;  1BHT A;  1Z40 A;  2X2Z A;  2QJ2 A;  4A5T S;  4R1B A;  4UV6 A;  5CSQ A;  2Z8V A;  5EOK A;  2Y8R A;  4Z0E A;  5CS5 A;  5EOD A;  4IUA A;  4Z0F A;  1YXE A;  3SRI A;  1W81 A;  3ZWZ A;  2QJ4 A;  3HMS A;  2YIO A;  4R19 A;  4R1C A;  3HMR A;  5CT1 A;  2HGF A;  2J8L A;  3HMT A;  5CP9 A;  4UAO A;  5I25 A;  2YIL A;  1GMO A;  1GMN A; 
#chains in the Genus database with same CATH homology
 2Z8W A;  2F83 A;  5COE A;  2Q8A A;  1I8N A;  1NK1 A;  4DUR A;  5CS9 A;  2J8J A;  4Z0D A;  3MKP A;  2KL5 A;  2Q8B A;  3HN4 A;  5CT2 A;  5CT3 A;  5CS3 A;  4YIV A;  4APM A;  1GP9 A;  4APL A;  4YIZ A;  5CS1 A;  3SRJ A;  2YIP A;  4Z09 A;  3SP8 A;  4R1A A;  1W8K A;  3ZLE A;  1HKY A;  2LL3 A;  2LL4 M;  2K13 X;  1BHT A;  1Z40 A;  2X2Z A;  2QJ2 A;  4A5T S;  4R1B A;  4UV6 A;  5CSQ A;  2Z8V A;  5EOK A;  2Y8R A;  4Z0E A;  5CS5 A;  5EOD A;  4IUA A;  4Z0F A;  1YXE A;  3SRI A;  1W81 A;  3ZWZ A;  2QJ4 A;  3HMS A;  2YIO A;  4R19 A;  4R1C A;  3HMR A;  5CT1 A;  2HGF A;  2J8L A;  3HMT A;  5CP9 A;  4UAO A;  5I25 A;  2YIL A;  1GMO A;  1GMN A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...