4Z0FA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038(6cw)] peptide
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
332
structure length
278
Chain Sequence
GNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQYDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
total genus 75
structure length 278
sequence length 332
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0fA01
2QJ4A 4APLA 5I25A 4Z09A 5CS1A 2Q8AA 2Z8VA 1W8KA 5CT1A 1GP9A 1I8NA 2YIOA 4IUAA 4Z0EA 3ZLEA 5CS9A 4R19A 3HMRA 2YIPA 5EODA 5CP9A 5EOKA 1Z40A 2QJ2A 2HGFA 3SRIA 2LL3A 2Q8BA 1W81A 2F83A 2YILA 5CT2A 3HMTA 3SP8A 1NK1A 2Z8WA 5CT3A 2K13X 4Z0FA 1GMOA 3ZWZA 1HKYA 1GMNA 2J8JA 4R1AA 5CS3A 4R1BA 3SRJA 2J8LA 5COEA 4DURA 1BHTA 3HMSA 4R1CA 1YXEA 2Y8RA 5CSQA 5CS5A 3MKPA 2LL4M 2X2ZA 4A5TS 3HN4A 4UAOA 4UV6A 4APMA 4Z0DA
chains in the Genus database with same CATH superfamily
4YIVA 2QJ4A 4APLA 5I25A 4Z09A 5CS1A 2Q8AA 2KL5A 2Z8VA 1W8KA 5CT1A 1GP9A 1I8NA 2YIOA 4IUAA 4Z0EA 3ZLEA 5CS9A 4R19A 3HMRA 4YIZA 2YIPA 5EODA 5CP9A 5EOKA 1Z40A 2QJ2A 2HGFA 3SRIA 2LL3A 2Q8BA 1W81A 2F83A 2YILA 5CT2A 3HMTA 3SP8A 1NK1A 2Z8WA 5CT3A 2K13X 4Z0FA 1GMOA 3ZWZA 1HKYA 1GMNA 2J8JA 4R1AA 5CS3A 4R1BA 3SRJA 2J8LA 5COEA 4DURA 1BHTA 3HMSA 4R1CA 1YXEA 2Y8RA 5CSQA 5CS5A 3MKPA 2LL4M 2X2ZA 4A5TS 3HN4A 4UAOA 4UV6A 4APMA 4Z0DA
chains in the Genus database with same CATH topology
4YIVA 2QJ4A 4APLA 5I25A 4Z09A 5CS1A 2Q8AA 2KL5A 2Z8VA 1W8KA 5CT1A 1GP9A 1I8NA 2YIOA 4IUAA 4Z0EA 3ZLEA 5CS9A 4R19A 3HMRA 4YIZA 2YIPA 5EODA 5CP9A 5EOKA 1Z40A 2QJ2A 2HGFA 3SRIA 2LL3A 2Q8BA 1W81A 2F83A 2YILA 5CT2A 3HMTA 3SP8A 1NK1A 2Z8WA 5CT3A 2K13X 4Z0FA 1GMOA 3ZWZA 1HKYA 1GMNA 2J8JA 4R1AA 5CS3A 4R1BA 3SRJA 2J8LA 5COEA 4DURA 1BHTA 3HMSA 4R1CA 1YXEA 2Y8RA 5CSQA 5CS5A 3MKPA 2LL4M 2X2ZA 4A5TS 3HN4A 4UAOA 4UV6A 4APMA 4Z0DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJ4 A;  4APL A;  5I25 A;  4Z09 A;  5CS1 A;  2Q8A A;  2Z8V A;  1W8K A;  5CT1 A;  1GP9 A;  1I8N A;  2YIO A;  4IUA A;  4Z0E A;  3ZLE A;  5CS9 A;  4R19 A;  3HMR A;  2YIP A;  5EOD A;  5CP9 A;  5EOK A;  1Z40 A;  2QJ2 A;  2HGF A;  3SRI A;  2LL3 A;  2Q8B A;  1W81 A;  2F83 A;  2YIL A;  5CT2 A;  3HMT A;  3SP8 A;  1NK1 A;  2Z8W A;  5CT3 A;  2K13 X;  4Z0F A;  1GMO A;  3ZWZ A;  1HKY A;  1GMN A;  2J8J A;  4R1A A;  5CS3 A;  4R1B A;  3SRJ A;  2J8L A;  5COE A;  4DUR A;  1BHT A;  3HMS A;  4R1C A;  1YXE A;  2Y8R A;  5CSQ A;  5CS5 A;  3MKP A;  2LL4 M;  2X2Z A;  4A5T S;  3HN4 A;  4UAO A;  4UV6 A;  4APM A;  4Z0D A; 
#chains in the Genus database with same CATH topology
 4YIV A;  2QJ4 A;  4APL A;  5I25 A;  4Z09 A;  5CS1 A;  2Q8A A;  2KL5 A;  2Z8V A;  1W8K A;  5CT1 A;  1GP9 A;  1I8N A;  2YIO A;  4IUA A;  4Z0E A;  3ZLE A;  5CS9 A;  4R19 A;  3HMR A;  4YIZ A;  2YIP A;  5EOD A;  5CP9 A;  5EOK A;  1Z40 A;  2QJ2 A;  2HGF A;  3SRI A;  2LL3 A;  2Q8B A;  1W81 A;  2F83 A;  2YIL A;  5CT2 A;  3HMT A;  3SP8 A;  1NK1 A;  2Z8W A;  5CT3 A;  2K13 X;  4Z0F A;  1GMO A;  3ZWZ A;  1HKY A;  1GMN A;  2J8J A;  4R1A A;  5CS3 A;  4R1B A;  3SRJ A;  2J8L A;  5COE A;  4DUR A;  1BHT A;  3HMS A;  4R1C A;  1YXE A;  2Y8R A;  5CSQ A;  5CS5 A;  3MKP A;  2LL4 M;  2X2Z A;  4A5T S;  3HN4 A;  4UAO A;  4UV6 A;  4APM A;  4Z0D A; 
#chains in the Genus database with same CATH homology
 4YIV A;  2QJ4 A;  4APL A;  5I25 A;  4Z09 A;  5CS1 A;  2Q8A A;  2KL5 A;  2Z8V A;  1W8K A;  5CT1 A;  1GP9 A;  1I8N A;  2YIO A;  4IUA A;  4Z0E A;  3ZLE A;  5CS9 A;  4R19 A;  3HMR A;  4YIZ A;  2YIP A;  5EOD A;  5CP9 A;  5EOK A;  1Z40 A;  2QJ2 A;  2HGF A;  3SRI A;  2LL3 A;  2Q8B A;  1W81 A;  2F83 A;  2YIL A;  5CT2 A;  3HMT A;  3SP8 A;  1NK1 A;  2Z8W A;  5CT3 A;  2K13 X;  4Z0F A;  1GMO A;  3ZWZ A;  1HKY A;  1GMN A;  2J8J A;  4R1A A;  5CS3 A;  4R1B A;  3SRJ A;  2J8L A;  5COE A;  4DUR A;  1BHT A;  3HMS A;  4R1C A;  1YXE A;  2Y8R A;  5CSQ A;  5CS5 A;  3MKP A;  2LL4 M;  2X2Z A;  4A5T S;  3HN4 A;  4UAO A;  4UV6 A;  4APM A;  4Z0D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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