4Z0FA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038(6cw)] peptide
Total Genus 75

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
332
structure length
278
Chain Sequence
GNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQYDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTIV7 (227-231)TII1 (151-154)S3 (151-152)3H1 (112-117)TI1 (108-111)TI2 (164-167)TIV1 (126-129)TIV2 (136-139)S1 (133-137)TVIII1 (127-130)S2 (140-144)S4 (154-158)TIV3 (158-161)TI3 (176-179)TIV9 (257-275)AH2 (195-202)S6 (238-241)TIV4 (186-189)S5 (193-194)TIV5 (190-193)TVIII3 (250-253)S7 (246-249)TI4 (202-205)TIV8 (241-244)TI5 (205-208)AH3 (213-222)TIV6 (206-209)TI6 (208-211)TVIII2 (225-228)TI7 (242-245)S8 (276-280)AH1 (119-123)Updating...
connected with : NaN
molecule tags Cell invasion
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
total genus 75
structure length 278
sequence length 332
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0fA01
2Y8RA 4UV6A 5COEA 2LL3A 4APMA 5CS9A 1NK1A 3MKPA 1HKYA 2QJ4A 2F83A 1YXEA 2YIPA 1W8KA 5CSQA 5CT1A 3HMSA 3HN4A 2Q8AA 1GMNA 2YILA 5CT3A 5CP9A 2HGFA 1BHTA 2J8JA 4R19A 4R1CA 4Z09A 4Z0DA 4Z0EA 3ZLEA 3SRJA 4APLA 5I25A 3HMTA 2QJ2A 3SRIA 5EODA 3SP8A 2Q8BA 4R1BA 2LL4M 1GMOA 4IUAA 5CT2A 2X2ZA 3HMRA 2Z8VA 4UAOA 4A5TS 1Z40A 5CS5A 1I8NA 1GP9A 2J8LA 4R1AA 5EOKA 4Z0FA 5CS1A 2Z8WA 3ZWZA 2YIOA 5CS3A 4DURA 2K13X 1W81A
chains in the Genus database with same CATH superfamily
2Y8RA 4UV6A 5COEA 2LL3A 4APMA 5CS9A 1NK1A 3MKPA 1HKYA 2QJ4A 2F83A 1YXEA 2YIPA 1W8KA 5CSQA 5CT1A 3HMSA 2KL5A 3HN4A 2Q8AA 1GMNA 2YILA 5CT3A 5CP9A 2HGFA 1BHTA 2J8JA 4R19A 4R1CA 4Z09A 4Z0DA 4Z0EA 3ZLEA 3SRJA 4APLA 5I25A 3HMTA 2QJ2A 3SRIA 4YIVA 4YIZA 5EODA 3SP8A 2Q8BA 4R1BA 2LL4M 1GMOA 4IUAA 5CT2A 2X2ZA 3HMRA 2Z8VA 4UAOA 4A5TS 1Z40A 5CS5A 1I8NA 1GP9A 2J8LA 4R1AA 5EOKA 4Z0FA 5CS1A 2Z8WA 3ZWZA 2YIOA 5CS3A 4DURA 2K13X 1W81A
chains in the Genus database with same CATH topology
2Y8RA 4UV6A 5COEA 2LL3A 4APMA 5CS9A 1NK1A 3MKPA 1HKYA 2QJ4A 2F83A 1YXEA 2YIPA 1W8KA 5CSQA 5CT1A 3HMSA 2KL5A 3HN4A 2Q8AA 1GMNA 2YILA 5CT3A 5CP9A 2HGFA 1BHTA 2J8JA 4R19A 4R1CA 4Z09A 4Z0DA 4Z0EA 3ZLEA 3SRJA 4APLA 5I25A 3HMTA 2QJ2A 3SRIA 4YIVA 4YIZA 5EODA 3SP8A 2Q8BA 4R1BA 2LL4M 1GMOA 4IUAA 5CT2A 2X2ZA 3HMRA 2Z8VA 4UAOA 4A5TS 1Z40A 5CS5A 1I8NA 1GP9A 2J8LA 4R1AA 5EOKA 4Z0FA 5CS1A 2Z8WA 3ZWZA 2YIOA 5CS3A 4DURA 2K13X 1W81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y8R A;  4UV6 A;  5COE A;  2LL3 A;  4APM A;  5CS9 A;  1NK1 A;  3MKP A;  1HKY A;  2QJ4 A;  2F83 A;  1YXE A;  2YIP A;  1W8K A;  5CSQ A;  5CT1 A;  3HMS A;  3HN4 A;  2Q8A A;  1GMN A;  2YIL A;  5CT3 A;  5CP9 A;  2HGF A;  1BHT A;  2J8J A;  4R19 A;  4R1C A;  4Z09 A;  4Z0D A;  4Z0E A;  3ZLE A;  3SRJ A;  4APL A;  5I25 A;  3HMT A;  2QJ2 A;  3SRI A;  5EOD A;  3SP8 A;  2Q8B A;  4R1B A;  2LL4 M;  1GMO A;  4IUA A;  5CT2 A;  2X2Z A;  3HMR A;  2Z8V A;  4UAO A;  4A5T S;  1Z40 A;  5CS5 A;  1I8N A;  1GP9 A;  2J8L A;  4R1A A;  5EOK A;  4Z0F A;  5CS1 A;  2Z8W A;  3ZWZ A;  2YIO A;  5CS3 A;  4DUR A;  2K13 X;  1W81 A; 
#chains in the Genus database with same CATH topology
 2Y8R A;  4UV6 A;  5COE A;  2LL3 A;  4APM A;  5CS9 A;  1NK1 A;  3MKP A;  1HKY A;  2QJ4 A;  2F83 A;  1YXE A;  2YIP A;  1W8K A;  5CSQ A;  5CT1 A;  3HMS A;  2KL5 A;  3HN4 A;  2Q8A A;  1GMN A;  2YIL A;  5CT3 A;  5CP9 A;  2HGF A;  1BHT A;  2J8J A;  4R19 A;  4R1C A;  4Z09 A;  4Z0D A;  4Z0E A;  3ZLE A;  3SRJ A;  4APL A;  5I25 A;  3HMT A;  2QJ2 A;  3SRI A;  4YIV A;  4YIZ A;  5EOD A;  3SP8 A;  2Q8B A;  4R1B A;  2LL4 M;  1GMO A;  4IUA A;  5CT2 A;  2X2Z A;  3HMR A;  2Z8V A;  4UAO A;  4A5T S;  1Z40 A;  5CS5 A;  1I8N A;  1GP9 A;  2J8L A;  4R1A A;  5EOK A;  4Z0F A;  5CS1 A;  2Z8W A;  3ZWZ A;  2YIO A;  5CS3 A;  4DUR A;  2K13 X;  1W81 A; 
#chains in the Genus database with same CATH homology
 2Y8R A;  4UV6 A;  5COE A;  2LL3 A;  4APM A;  5CS9 A;  1NK1 A;  3MKP A;  1HKY A;  2QJ4 A;  2F83 A;  1YXE A;  2YIP A;  1W8K A;  5CSQ A;  5CT1 A;  3HMS A;  2KL5 A;  3HN4 A;  2Q8A A;  1GMN A;  2YIL A;  5CT3 A;  5CP9 A;  2HGF A;  1BHT A;  2J8J A;  4R19 A;  4R1C A;  4Z09 A;  4Z0D A;  4Z0E A;  3ZLE A;  3SRJ A;  4APL A;  5I25 A;  3HMT A;  2QJ2 A;  3SRI A;  4YIV A;  4YIZ A;  5EOD A;  3SP8 A;  2Q8B A;  4R1B A;  2LL4 M;  1GMO A;  4IUA A;  5CT2 A;  2X2Z A;  3HMR A;  2Z8V A;  4UAO A;  4A5T S;  1Z40 A;  5CS5 A;  1I8N A;  1GP9 A;  2J8L A;  4R1A A;  5EOK A;  4Z0F A;  5CS1 A;  2Z8W A;  3ZWZ A;  2YIO A;  5CS3 A;  4DUR A;  2K13 X;  1W81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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