5BVIA

X-ray structure of interferon regulatory factor 4 iad domain
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
IRSAEALALSDCRLHICLYYRDILVKELTTTSPEGCRISHGHTYDVSNLDQVLFPYPDDNGQRKNIEKLLSHLERGLVLWMAPDGLYAKRLCQSRIYWDGPLALCSDRPNKLERDQTCKLFDTQQFLSELQVFAHHGRPAPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Interferon regulatory factor 4
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10401 IRF-3 Interferon-regulatory factor 3
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.10 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 5bviA00
1QWTA 1U7VB 1KHXA 5JEOA 1U7VA 1U7FB 3A77A 5BVIA 3DSHA 1U7FA 1DD1A 5C4VA 1YGSA 5JEMA 1G88A 5JERA 1J2FA 1MK2A 1MJSA 1KHUA 1MR1A 5JEJA 1DEVA 5JEKA 3DITA 4R9PA 1ZOQA 5JELA 3GMJA
chains in the Genus database with same CATH superfamily
1UJXA 2JGRA 2BONA 2JQIA 3V7UA 2I2AA 1G6GA 3GQSA 3DSHA 1U0TA 5DHUA 1UHTA 3GMJA 3V7YA 5EJFA 1QU5A 2I2FA 1LGPA 1YGSA 2I29A 4V24A 2I2DA 1J2FA 1MR1A 4H87A 1Z0UA 5EJGA 2G1LA 3UOTA 1DEVA 5JEKA 5EJIA 1FHQA 1Z0SA 3DITA 2KB3A 4KU0D 1ZOQA 4WRRA 4DY6A 2I1WA 3ELVA 1Z0ZA 4JIVD 1KHXA 2LC1A 1YJMA 3I0NA 1R21A 1G3GA 1LGQA 3T5PA 1U7FA 1DD1A 1J4PA 4A0EA 5DJOA 5C4VA 4JONA 4JIWD 3UNMA 1G88A 2EH0A 5EJHA 1KHUA 3UNNA 1Y3IA 2P1RA 2KFUA 3UMZA 3VA1A 1J4QA 1FHRA 2JQLA 2CSWA 3PO8A 3UV0A 2XT9B 1WV3A 2AFFA 2QV7A 1K3NA 3V7WA 3I6WA 3VZBA 3VZCA 5JELA 1QWTA 1K2NA 3HUEA 1K3QA 4G2SA 5A8IA 5JEOA 4L02A 3POAA 2JKDA 1U7VA 1K3JA 5BVIA 1Y3HA 2A0TA 4QCJA 5DHRA 2I2CA 5JEMA 4EGXA 2FEZA 3KT9A 4HAOA 1J4KA 3S40A 2W3OA 4EJQA 3HUFA 3VPYA 1YJ5C 2KKLA 4R9PA 4A4YA 2XXSA 4WERA 2QVLA 1GXCA 1U7VB 5DHQA 1U0RA 3I6UA 3OUNA 5E50A 1SUWA 1U7FB 3VA4A 3A77A 5DHTA 3V8NA 3AFOA 2Q5FA 2JPEA 3MDBA 3VZDA 3UN0A 2KB4A 3PFNA 3V8MA 3V80A 5DHPA 5JERA 4D9VA 2I2BA 2BRFA 3ELSA 3HX1A 1DMZA 1MK2A 1MJSA 1K2MA 5JEJA 2JQJA 1J4LA 1J4OA 2PIEA 3I0MA 1WLNA 1MZKA 3V8RA 3V8PA 2FF4A 1YT5A 5DHSA 3V8QA 2AN1A 3FM8A
chains in the Genus database with same CATH topology
1UJXA 2JGRA 2BONA 2JQIA 1G6GA 3GQSA 3DSHA 1UHTA 1QU5A 1LGPA 1YGSA 4V24A 1J2FA 1MR1A 4H87A 2G1LA 3UOTA 1DEVA 5JEKA 1FHQA 3DITA 2KB3A 4KU0D 1ZOQA 4WRRA 3ELVA 4JIVD 1KHXA 2LC1A 1YJMA 3I0NA 1R21A 1G3GA 1LGQA 3T5PA 1U7FA 1DD1A 1J4PA 4A0EA 5DJOA 5C4VA 4JONA 4JIWD 3UNMA 1G88A 2EH0A 1KHUA 3UNNA 2P1RA 2KFUA 3UMZA 3VA1A 1J4QA 1FHRA 2JQLA 2CSWA 3PO8A 3UV0A 2XT9B 1WV3A 2AFFA 2QV7A 1K3NA 5JELA 3I6WA 3VZBA 3VZCA 1QWTA 1K2NA 3HUEA 1K3QA 4G2SA 5A8IA 5JEOA 4L02A 3POAA 2JKDA 1U7VA 1K3JA 5BVIA 2A0TA 4QCJA 5JEMA 4EGXA 2FEZA 3KT9A 1J4KA 3S40A 2W3OA 4EJQA 3HUFA 3VPYA 1YJ5C 2KKLA 4R9PA 4A4YA 2XXSA 4WERA 2QVLA 1GXCA 1U7VB 3I6UA 3OUNA 5E50A 1U7FB 3VA4A 3A77A 2JPEA 3MDBA 3VZDA 3UN0A 2KB4A 5JERA 4D9VA 3ELSA 2BRFA 1DMZA 3HX1A 1MK2A 1MJSA 1K2MA 5JEJA 2JQJA 1J4LA 1J4OA 2PIEA 3I0MA 1WLNA 1MZKA 2FF4A 3GMJA 3FM8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QWT A;  1U7V B;  1KHX A;  5JEO A;  1U7V A;  1U7F B;  3A77 A;  5BVI A;  3DSH A;  1U7F A;  1DD1 A;  5C4V A;  1YGS A;  5JEM A;  1G88 A;  5JER A;  1J2F A;  1MK2 A;  1MJS A;  1KHU A;  1MR1 A;  5JEJ A;  1DEV A;  5JEK A;  3DIT A;  4R9P A;  1ZOQ A;  5JEL A;  3GMJ A; 
#chains in the Genus database with same CATH topology
 1UJX A;  2JGR A;  2BON A;  2JQI A;  3V7U A;  2I2A A;  1G6G A;  3GQS A;  3DSH A;  1U0T A;  5DHU A;  1UHT A;  3GMJ A;  3V7Y A;  5EJF A;  1QU5 A;  2I2F A;  1LGP A;  1YGS A;  2I29 A;  4V24 A;  2I2D A;  1J2F A;  1MR1 A;  4H87 A;  1Z0U A;  5EJG A;  2G1L A;  3UOT A;  1DEV A;  5JEK A;  5EJI A;  1FHQ A;  1Z0S A;  3DIT A;  2KB3 A;  4KU0 D;  1ZOQ A;  4WRR A;  4DY6 A;  2I1W A;  3ELV A;  1Z0Z A;  4JIV D;  1KHX A;  2LC1 A;  1YJM A;  3I0N A;  1R21 A;  1G3G A;  1LGQ A;  3T5P A;  1U7F A;  1DD1 A;  1J4P A;  4A0E A;  5DJO A;  5C4V A;  4JON A;  4JIW D;  3UNM A;  1G88 A;  2EH0 A;  5EJH A;  1KHU A;  3UNN A;  1Y3I A;  2P1R A;  2KFU A;  3UMZ A;  3VA1 A;  1J4Q A;  1FHR A;  2JQL A;  2CSW A;  3PO8 A;  3UV0 A;  2XT9 B;  1WV3 A;  2AFF A;  2QV7 A;  1K3N A;  3V7W A;  3I6W A;  3VZB A;  3VZC A;  5JEL A;  1QWT A;  1K2N A;  3HUE A;  1K3Q A;  4G2S A;  5A8I A;  5JEO A;  4L02 A;  3POA A;  2JKD A;  1U7V A;  1K3J A;  5BVI A;  1Y3H A;  2A0T A;  4QCJ A;  5DHR A;  2I2C A;  5JEM A;  4EGX A;  2FEZ A;  3KT9 A;  4HAO A;  1J4K A;  3S40 A;  2W3O A;  4EJQ A;  3HUF A;  3VPY A;  1YJ5 C;  2KKL A;  4R9P A;  4A4Y A;  2XXS A;  4WER A;  2QVL A;  1GXC A;  1U7V B;  5DHQ A;  1U0R A;  3I6U A;  3OUN A;  5E50 A;  1SUW A;  1U7F B;  3VA4 A;  3A77 A;  5DHT A;  3V8N A;  3AFO A;  2Q5F A;  2JPE A;  3MDB A;  3VZD A;  3UN0 A;  2KB4 A;  3PFN A;  3V8M A;  3V80 A;  5DHP A;  5JER A;  4D9V A;  2I2B A;  2BRF A;  3ELS A;  3HX1 A;  1DMZ A;  1MK2 A;  1MJS A;  1K2M A;  5JEJ A;  2JQJ A;  1J4L A;  1J4O A;  2PIE A;  3I0M A;  1WLN A;  1MZK A;  3V8R A;  3V8P A;  2FF4 A;  1YT5 A;  5DHS A;  3V8Q A;  2AN1 A;  3FM8 A; 
#chains in the Genus database with same CATH homology
 1UJX A;  2JGR A;  2BON A;  2JQI A;  1G6G A;  3GQS A;  3DSH A;  1UHT A;  1QU5 A;  1LGP A;  1YGS A;  4V24 A;  1J2F A;  1MR1 A;  4H87 A;  2G1L A;  3UOT A;  1DEV A;  5JEK A;  1FHQ A;  3DIT A;  2KB3 A;  4KU0 D;  1ZOQ A;  4WRR A;  3ELV A;  4JIV D;  1KHX A;  2LC1 A;  1YJM A;  3I0N A;  1R21 A;  1G3G A;  1LGQ A;  3T5P A;  1U7F A;  1DD1 A;  1J4P A;  4A0E A;  5DJO A;  5C4V A;  4JON A;  4JIW D;  3UNM A;  1G88 A;  2EH0 A;  1KHU A;  3UNN A;  2P1R A;  2KFU A;  3UMZ A;  3VA1 A;  1J4Q A;  1FHR A;  2JQL A;  2CSW A;  3PO8 A;  3UV0 A;  2XT9 B;  1WV3 A;  2AFF A;  2QV7 A;  1K3N A;  5JEL A;  3I6W A;  3VZB A;  3VZC A;  1QWT A;  1K2N A;  3HUE A;  1K3Q A;  4G2S A;  5A8I A;  5JEO A;  4L02 A;  3POA A;  2JKD A;  1U7V A;  1K3J A;  5BVI A;  2A0T A;  4QCJ A;  5JEM A;  4EGX A;  2FEZ A;  3KT9 A;  1J4K A;  3S40 A;  2W3O A;  4EJQ A;  3HUF A;  3VPY A;  1YJ5 C;  2KKL A;  4R9P A;  4A4Y A;  2XXS A;  4WER A;  2QVL A;  1GXC A;  1U7V B;  3I6U A;  3OUN A;  5E50 A;  1U7F B;  3VA4 A;  3A77 A;  2JPE A;  3MDB A;  3VZD A;  3UN0 A;  2KB4 A;  5JER A;  4D9V A;  3ELS A;  2BRF A;  1DMZ A;  3HX1 A;  1MK2 A;  1MJS A;  1K2M A;  5JEJ A;  2JQJ A;  1J4L A;  1J4O A;  2PIE A;  3I0M A;  1WLN A;  1MZK A;  2FF4 A;  3GMJ A;  3FM8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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