5BVIA

X-ray structure of interferon regulatory factor 4 iad domain
Total Genus 48
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
IRSAEALALSDCRLHICLYYRDILVKELTTTSPEGCRISHGHTYDVSNLDQVLFPYPDDNGQRKNIEKLLSHLERGLVLWMAPDGLYAKRLCQSRIYWDGPLALCSDRPNKLERDQTCKLFDTQQFLSELQVFAHHGRPAPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Interferon regulatory factor 4
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10401 IRF-3 Interferon-regulatory factor 3
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.10 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 5bviA00
1MR1A 3DSHA 5JEJA 1DD1A 5JEKA 1J2FA 1KHXA 1QWTA 3DITA 3A77A 1U7VB 5BVIA 1ZOQA 1U7FB 5JEOA 1KHUA 1G88A 1U7VA 1U7FA 1MK2A 5JERA 5C4VA 1YGSA 3GMJA 5JELA 1DEVA 1MJSA 4R9PA 5JEMA
chains in the Genus database with same CATH superfamily
3DSHA 3V7UA 4D9VA 5E50A 5A8IA 2FEZA 1WV3A 2JQJA 5DHSA 3UOTA 1J2FA 1KHXA 3VA4A 4EJQA 1J4OA 2P1RA 3UN0A 5DHQA 2XT9B 3UMZA 3UNNA 3DITA 3A77A 3I6WA 3V8RA 1FHQA 1U7VB 5EJIA 4H87A 1R21A 2AN1A 2I2DA 1Y3IA 3PO8A 1U7FB 1FHRA 1KHUA 1Y3HA 1DMZA 1J4QA 1U7VA 2I2CA 3I0NA 1MZKA 4R9PA 4JIVD 5EJGA 1MR1A 4JIWD 4WERA 1Z0ZA 1K3NA 3VA1A 1K2NA 3ELVA 3VZCA 2KFUA 4WRRA 5DHRA 1J4LA 1UJXA 5DHUA 1YJ5C 3UV0A 3ELSA 3POAA 2JGRA 3MDBA 1Z0SA 2BRFA 4QCJA 3V7WA 5DHTA 4JONA 1K3JA 3HX1A 3V7YA 1ZOQA 3HUFA 1QU5A 2A0TA 1G3GA 3T5PA 1GXCA 2KB3A 2G1LA 4G2SA 3V8NA 5EJFA 2KB4A 1MJSA 3I0MA 2JQLA 3AFOA 1J4PA 5JEMA 2I2FA 1WLNA 3V80A 2JQIA 2I2BA 2JPEA 2BONA 2FF4A 4A0EA 3VZBA 3V8QA 2AFFA 3VPYA 4DY6A 1QWTA 1UHTA 5DJOA 5BVIA 5JEOA 3V8PA 4A4YA 2I1WA 1G88A 3PFNA 1LGQA 1MK2A 4V24A 1U0RA 5JERA 1YGSA 1Z0UA 4L02A 2QVLA 1J4KA 2JKDA 1LGPA 5JEJA 5EJHA 2Q5FA 2PIEA 2XXSA 3S40A 1U0TA 1G6GA 2EH0A 5DHPA 3UNMA 1DD1A 3V8MA 3HUEA 5JEKA 2W3OA 2KKLA 3VZDA 2CSWA 3OUNA 4KU0D 1K2MA 4EGXA 2I29A 2LC1A 3FM8A 1YT5A 3I6UA 1YJMA 1SUWA 3GQSA 1U7FA 5C4VA 2I2AA 3GMJA 5JELA 1DEVA 3KT9A 4HAOA 2QV7A 1K3QA
chains in the Genus database with same CATH topology
3DSHA 4D9VA 5E50A 5A8IA 2FEZA 1WV3A 2JQJA 3UOTA 1J2FA 1KHXA 3VA4A 4EJQA 1J4OA 2P1RA 3UN0A 2XT9B 3UMZA 3UNNA 3DITA 3A77A 3I6WA 1FHQA 1U7VB 4H87A 1R21A 3PO8A 1U7FB 1FHRA 1KHUA 1DMZA 1J4QA 1U7VA 3I0NA 1MZKA 4R9PA 4JIVD 1MR1A 4JIWD 4WERA 1K2NA 1K3NA 3VA1A 3ELVA 3VZCA 2KFUA 4WRRA 1J4LA 1UJXA 1YJ5C 3UV0A 3ELSA 3POAA 2JGRA 3MDBA 2BRFA 4QCJA 4JONA 1K3JA 3HX1A 1ZOQA 3HUFA 1QU5A 2A0TA 1G3GA 3T5PA 1GXCA 2KB3A 2G1LA 4G2SA 2KB4A 1MJSA 3I0MA 2JQLA 1J4PA 5JEMA 1WLNA 2JQIA 2JPEA 2BONA 2FF4A 4A0EA 3VZBA 2AFFA 3VPYA 1QWTA 1UHTA 5DJOA 5BVIA 5JEOA 4A4YA 1G88A 1LGQA 1MK2A 4V24A 5JERA 1YGSA 4L02A 2QVLA 1J4KA 2JKDA 1LGPA 5JEJA 2PIEA 2XXSA 3S40A 1G6GA 2EH0A 3UNMA 1DD1A 3HUEA 5JEKA 2W3OA 2KKLA 3VZDA 2CSWA 3OUNA 4KU0D 1K2MA 4EGXA 2LC1A 3FM8A 3I6UA 1YJMA 3GQSA 1U7FA 5C4VA 5JELA 3GMJA 1DEVA 3KT9A 2QV7A 1K3QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MR1 A;  3DSH A;  5JEJ A;  1DD1 A;  5JEK A;  1J2F A;  1KHX A;  1QWT A;  3DIT A;  3A77 A;  1U7V B;  5BVI A;  1ZOQ A;  1U7F B;  5JEO A;  1KHU A;  1G88 A;  1U7V A;  1U7F A;  1MK2 A;  5JER A;  5C4V A;  1YGS A;  3GMJ A;  5JEL A;  1DEV A;  1MJS A;  4R9P A;  5JEM A; 
#chains in the Genus database with same CATH topology
 3DSH A;  3V7U A;  4D9V A;  5E50 A;  5A8I A;  2FEZ A;  1WV3 A;  2JQJ A;  5DHS A;  3UOT A;  1J2F A;  1KHX A;  3VA4 A;  4EJQ A;  1J4O A;  2P1R A;  3UN0 A;  5DHQ A;  2XT9 B;  3UMZ A;  3UNN A;  3DIT A;  3A77 A;  3I6W A;  3V8R A;  1FHQ A;  1U7V B;  5EJI A;  4H87 A;  1R21 A;  2AN1 A;  2I2D A;  1Y3I A;  3PO8 A;  1U7F B;  1FHR A;  1KHU A;  1Y3H A;  1DMZ A;  1J4Q A;  1U7V A;  2I2C A;  3I0N A;  1MZK A;  4R9P A;  4JIV D;  5EJG A;  1MR1 A;  4JIW D;  4WER A;  1Z0Z A;  1K3N A;  3VA1 A;  1K2N A;  3ELV A;  3VZC A;  2KFU A;  4WRR A;  5DHR A;  1J4L A;  1UJX A;  5DHU A;  1YJ5 C;  3UV0 A;  3ELS A;  3POA A;  2JGR A;  3MDB A;  1Z0S A;  2BRF A;  4QCJ A;  3V7W A;  5DHT A;  4JON A;  1K3J A;  3HX1 A;  3V7Y A;  1ZOQ A;  3HUF A;  1QU5 A;  2A0T A;  1G3G A;  3T5P A;  1GXC A;  2KB3 A;  2G1L A;  4G2S A;  3V8N A;  5EJF A;  2KB4 A;  1MJS A;  3I0M A;  2JQL A;  3AFO A;  1J4P A;  5JEM A;  2I2F A;  1WLN A;  3V80 A;  2JQI A;  2I2B A;  2JPE A;  2BON A;  2FF4 A;  4A0E A;  3VZB A;  3V8Q A;  2AFF A;  3VPY A;  4DY6 A;  1QWT A;  1UHT A;  5DJO A;  5BVI A;  5JEO A;  3V8P A;  4A4Y A;  2I1W A;  1G88 A;  3PFN A;  1LGQ A;  1MK2 A;  4V24 A;  1U0R A;  5JER A;  1YGS A;  1Z0U A;  4L02 A;  2QVL A;  1J4K A;  2JKD A;  1LGP A;  5JEJ A;  5EJH A;  2Q5F A;  2PIE A;  2XXS A;  3S40 A;  1U0T A;  1G6G A;  2EH0 A;  5DHP A;  3UNM A;  1DD1 A;  3V8M A;  3HUE A;  5JEK A;  2W3O A;  2KKL A;  3VZD A;  2CSW A;  3OUN A;  4KU0 D;  1K2M A;  4EGX A;  2I29 A;  2LC1 A;  3FM8 A;  1YT5 A;  3I6U A;  1YJM A;  1SUW A;  3GQS A;  1U7F A;  5C4V A;  2I2A A;  3GMJ A;  5JEL A;  1DEV A;  3KT9 A;  4HAO A;  2QV7 A;  1K3Q A; 
#chains in the Genus database with same CATH homology
 3DSH A;  4D9V A;  5E50 A;  5A8I A;  2FEZ A;  1WV3 A;  2JQJ A;  3UOT A;  1J2F A;  1KHX A;  3VA4 A;  4EJQ A;  1J4O A;  2P1R A;  3UN0 A;  2XT9 B;  3UMZ A;  3UNN A;  3DIT A;  3A77 A;  3I6W A;  1FHQ A;  1U7V B;  4H87 A;  1R21 A;  3PO8 A;  1U7F B;  1FHR A;  1KHU A;  1DMZ A;  1J4Q A;  1U7V A;  3I0N A;  1MZK A;  4R9P A;  4JIV D;  1MR1 A;  4JIW D;  4WER A;  1K2N A;  1K3N A;  3VA1 A;  3ELV A;  3VZC A;  2KFU A;  4WRR A;  1J4L A;  1UJX A;  1YJ5 C;  3UV0 A;  3ELS A;  3POA A;  2JGR A;  3MDB A;  2BRF A;  4QCJ A;  4JON A;  1K3J A;  3HX1 A;  1ZOQ A;  3HUF A;  1QU5 A;  2A0T A;  1G3G A;  3T5P A;  1GXC A;  2KB3 A;  2G1L A;  4G2S A;  2KB4 A;  1MJS A;  3I0M A;  2JQL A;  1J4P A;  5JEM A;  1WLN A;  2JQI A;  2JPE A;  2BON A;  2FF4 A;  4A0E A;  3VZB A;  2AFF A;  3VPY A;  1QWT A;  1UHT A;  5DJO A;  5BVI A;  5JEO A;  4A4Y A;  1G88 A;  1LGQ A;  1MK2 A;  4V24 A;  5JER A;  1YGS A;  4L02 A;  2QVL A;  1J4K A;  2JKD A;  1LGP A;  5JEJ A;  2PIE A;  2XXS A;  3S40 A;  1G6G A;  2EH0 A;  3UNM A;  1DD1 A;  3HUE A;  5JEK A;  2W3O A;  2KKL A;  3VZD A;  2CSW A;  3OUN A;  4KU0 D;  1K2M A;  4EGX A;  2LC1 A;  3FM8 A;  3I6U A;  1YJM A;  3GQS A;  1U7F A;  5C4V A;  5JEL A;  3GMJ A;  1DEV A;  3KT9 A;  2QV7 A;  1K3Q A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...