5JERA

Structure of rotavirus nsp1 bound to irf-3
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
234
structure length
234
Chain Sequence
ENPLKRLLVPGEEWEFEVTAFYRGRQVFQQTISCPEGLRLVGSEVGDRTLPGWPVTLPDPGMSLTDRGVMSYVRHVLSCLGGGLALWRAGQWLWAQRLGHCHTYWAVSEELLPNSGHGPDGEVPKDKEGGVFDLGPFIVDLITFTEGSGRSPRYALWFCVGESWPQDQPWTKRLVMVKVVPTCLRALVEMARVGGASSLENTVDLHISNSHPLSLTSDQYKAYLQDLVEGMDFQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.
pubmed doi rcsb
molecule tags Immune system
source organism Rotavirus a
molecule keywords Rotavirus NSP1 peptide
total genus 52
structure length 234
sequence length 234
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2016-04-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10401 IRF-3 Interferon-regulatory factor 3
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.10 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 5jerA00
1QWTA 3DITA 1KHXA 1MK2A 1U7VB 1YGSA 1U7FB 4R9PA 3A77A 5JEMA 5BVIA 1ZOQA 5C4VA 3GMJA 1J2FA 5JERA 1DEVA 3DSHA 1DD1A 5JEOA 1U7VA 1KHUA 5JEJA 1U7FA 1G88A 1MJSA 5JEKA 1MR1A 5JELA
chains in the Genus database with same CATH superfamily
5EJFA 2JQIA 2JPEA 4V24A 2Q5FA 1UJXA 1J4QA 4KU0D 1WLNA 4R9PA 3A77A 2P1RA 1YT5A 5DHTA 5EJIA 5A8IA 2I2CA 2QVLA 4JIVD 4JONA 2AN1A 1MZKA 1GXCA 2I2DA 3UV0A 4HAOA 1Y3HA 1DD1A 1Z0ZA 3VZDA 5DJOA 1Y3IA 5DHQA 3VA1A 5JEJA 4G2SA 1U7FA 3UN0A 1MJSA 2KFUA 1MR1A 5EJHA 2LC1A 1R21A 1J4LA 4QCJA 1G3GA 3V8PA 1QWTA 1WV3A 1KHXA 2I1WA 1DMZA 1YGSA 1U7FB 4H87A 2AFFA 5BVIA 3UMZA 3VPYA 1LGPA 3UNMA 5JERA 3KT9A 1DEVA 1U0TA 3HUFA 3UOTA 1FHRA 5JEOA 2XXSA 2BONA 2G1LA 4L02A 5EJGA 3AFOA 5DHSA 1K2MA 3VA4A 5DHUA 5JEKA 4D9VA 5JELA 2I2BA 3UNNA 4DY6A 3GQSA 4WERA 3I6UA 1UHTA 2XT9B 5E50A 2EH0A 3DITA 1Z0UA 2JQLA 2KB4A 2KB3A 1MK2A 1U0RA 3PFNA 2W3OA 3ELSA 3V8QA 1G6GA 1K3NA 4EGXA 1ZOQA 2JQJA 4WRRA 1J4OA 5DHPA 4A0EA 2FEZA 2I2AA 1YJ5C 3GMJA 3VZBA 1Z0SA 1K3JA 3FM8A 1U7VA 1KHUA 3V8RA 1G88A 3T5PA 3V7UA 3V7YA 2BRFA 3MDBA 2JKDA 2CSWA 1K2NA 1YJMA 2PIEA 5DHRA 3V80A 1K3QA 3S40A 1U7VB 4EJQA 3PO8A 2I2FA 1LGQA 1FHQA 5JEMA 3V7WA 5C4VA 3VZCA 1J4KA 1J2FA 2QV7A 2FF4A 3I6WA 3DSHA 4JIWD 2I29A 3ELVA 3HX1A 3OUNA 3POAA 3I0NA 2KKLA 1J4PA 3HUEA 3V8MA 2JGRA 1QU5A 3I0MA 3V8NA 4A4YA 1SUWA 2A0TA
chains in the Genus database with same CATH topology
2JQIA 2JPEA 4V24A 1UJXA 1J4QA 4KU0D 1WLNA 4R9PA 3A77A 2P1RA 5A8IA 2QVLA 4JIVD 4JONA 1MZKA 1GXCA 3UV0A 1DD1A 3VZDA 5DJOA 3VA1A 5JEJA 4G2SA 1U7FA 3UN0A 1MJSA 2KFUA 1MR1A 2LC1A 1R21A 1J4LA 4QCJA 1G3GA 1QWTA 1WV3A 1KHXA 1DMZA 1YGSA 1U7FB 4H87A 2AFFA 5BVIA 3UMZA 3VPYA 1LGPA 3UNMA 5JERA 3KT9A 1DEVA 3HUFA 3UOTA 1FHRA 5JEOA 2XXSA 2BONA 2G1LA 4L02A 1K2MA 3VA4A 5JEKA 4D9VA 5JELA 3UNNA 3GQSA 4WERA 3I6UA 1UHTA 2XT9B 5E50A 2EH0A 3DITA 2KB4A 2JQLA 2KB3A 1MK2A 2W3OA 3ELSA 1G6GA 1K3NA 4EGXA 1ZOQA 2JQJA 4WRRA 1J4OA 4A0EA 2FEZA 1YJ5C 3GMJA 3VZBA 1K3JA 3FM8A 1U7VA 1KHUA 1G88A 3T5PA 2BRFA 3MDBA 2JKDA 2CSWA 1YJMA 2PIEA 1K3QA 3S40A 1U7VB 4EJQA 3PO8A 1LGQA 1FHQA 5JEMA 5C4VA 3VZCA 1J4KA 1J2FA 2QV7A 2FF4A 3I6WA 3DSHA 4JIWD 3ELVA 3HX1A 3OUNA 3POAA 3I0NA 2KKLA 1J4PA 3HUEA 2JGRA 1QU5A 3I0MA 4A4YA 1K2NA 2A0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QWT A;  3DIT A;  1KHX A;  1MK2 A;  1U7V B;  1YGS A;  1U7F B;  4R9P A;  3A77 A;  5JEM A;  5BVI A;  1ZOQ A;  5C4V A;  3GMJ A;  1J2F A;  5JER A;  1DEV A;  3DSH A;  1DD1 A;  5JEO A;  1U7V A;  1KHU A;  5JEJ A;  1U7F A;  1G88 A;  1MJS A;  5JEK A;  1MR1 A;  5JEL A; 
#chains in the Genus database with same CATH topology
 5EJF A;  2JQI A;  2JPE A;  4V24 A;  2Q5F A;  1UJX A;  1J4Q A;  4KU0 D;  1WLN A;  4R9P A;  3A77 A;  2P1R A;  1YT5 A;  5DHT A;  5EJI A;  5A8I A;  2I2C A;  2QVL A;  4JIV D;  4JON A;  2AN1 A;  1MZK A;  1GXC A;  2I2D A;  3UV0 A;  4HAO A;  1Y3H A;  1DD1 A;  1Z0Z A;  3VZD A;  5DJO A;  1Y3I A;  5DHQ A;  3VA1 A;  5JEJ A;  4G2S A;  1U7F A;  3UN0 A;  1MJS A;  2KFU A;  1MR1 A;  5EJH A;  2LC1 A;  1R21 A;  1J4L A;  4QCJ A;  1G3G A;  3V8P A;  1QWT A;  1WV3 A;  1KHX A;  2I1W A;  1DMZ A;  1YGS A;  1U7F B;  4H87 A;  2AFF A;  5BVI A;  3UMZ A;  3VPY A;  1LGP A;  3UNM A;  5JER A;  3KT9 A;  1DEV A;  1U0T A;  3HUF A;  3UOT A;  1FHR A;  5JEO A;  2XXS A;  2BON A;  2G1L A;  4L02 A;  5EJG A;  3AFO A;  5DHS A;  1K2M A;  3VA4 A;  5DHU A;  5JEK A;  4D9V A;  5JEL A;  2I2B A;  3UNN A;  4DY6 A;  3GQS A;  4WER A;  3I6U A;  1UHT A;  2XT9 B;  5E50 A;  2EH0 A;  3DIT A;  1Z0U A;  2JQL A;  2KB4 A;  2KB3 A;  1MK2 A;  1U0R A;  3PFN A;  2W3O A;  3ELS A;  3V8Q A;  1G6G A;  1K3N A;  4EGX A;  1ZOQ A;  2JQJ A;  4WRR A;  1J4O A;  5DHP A;  4A0E A;  2FEZ A;  2I2A A;  1YJ5 C;  3GMJ A;  3VZB A;  1Z0S A;  1K3J A;  3FM8 A;  1U7V A;  1KHU A;  3V8R A;  1G88 A;  3T5P A;  3V7U A;  3V7Y A;  2BRF A;  3MDB A;  2JKD A;  2CSW A;  1K2N A;  1YJM A;  2PIE A;  5DHR A;  3V80 A;  1K3Q A;  3S40 A;  1U7V B;  4EJQ A;  3PO8 A;  2I2F A;  1LGQ A;  1FHQ A;  5JEM A;  3V7W A;  5C4V A;  3VZC A;  1J4K A;  1J2F A;  2QV7 A;  2FF4 A;  3I6W A;  3DSH A;  4JIW D;  2I29 A;  3ELV A;  3HX1 A;  3OUN A;  3POA A;  3I0N A;  2KKL A;  1J4P A;  3HUE A;  3V8M A;  2JGR A;  1QU5 A;  3I0M A;  3V8N A;  4A4Y A;  1SUW A;  2A0T A; 
#chains in the Genus database with same CATH homology
 2JQI A;  2JPE A;  4V24 A;  1UJX A;  1J4Q A;  4KU0 D;  1WLN A;  4R9P A;  3A77 A;  2P1R A;  5A8I A;  2QVL A;  4JIV D;  4JON A;  1MZK A;  1GXC A;  3UV0 A;  1DD1 A;  3VZD A;  5DJO A;  3VA1 A;  5JEJ A;  4G2S A;  1U7F A;  3UN0 A;  1MJS A;  2KFU A;  1MR1 A;  2LC1 A;  1R21 A;  1J4L A;  4QCJ A;  1G3G A;  1QWT A;  1WV3 A;  1KHX A;  1DMZ A;  1YGS A;  1U7F B;  4H87 A;  2AFF A;  5BVI A;  3UMZ A;  3VPY A;  1LGP A;  3UNM A;  5JER A;  3KT9 A;  1DEV A;  3HUF A;  3UOT A;  1FHR A;  5JEO A;  2XXS A;  2BON A;  2G1L A;  4L02 A;  1K2M A;  3VA4 A;  5JEK A;  4D9V A;  5JEL A;  3UNN A;  3GQS A;  4WER A;  3I6U A;  1UHT A;  2XT9 B;  5E50 A;  2EH0 A;  3DIT A;  2KB4 A;  2JQL A;  2KB3 A;  1MK2 A;  2W3O A;  3ELS A;  1G6G A;  1K3N A;  4EGX A;  1ZOQ A;  2JQJ A;  4WRR A;  1J4O A;  4A0E A;  2FEZ A;  1YJ5 C;  3GMJ A;  3VZB A;  1K3J A;  3FM8 A;  1U7V A;  1KHU A;  1G88 A;  3T5P A;  2BRF A;  3MDB A;  2JKD A;  2CSW A;  1YJM A;  2PIE A;  1K3Q A;  3S40 A;  1U7V B;  4EJQ A;  3PO8 A;  1LGQ A;  1FHQ A;  5JEM A;  5C4V A;  3VZC A;  1J4K A;  1J2F A;  2QV7 A;  2FF4 A;  3I6W A;  3DSH A;  4JIW D;  3ELV A;  3HX1 A;  3OUN A;  3POA A;  3I0N A;  2KKL A;  1J4P A;  3HUE A;  2JGR A;  1QU5 A;  3I0M A;  4A4Y A;  1K2N A;  2A0T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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