The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
16
|
sequence length |
110
|
structure length |
110
|
Chain Sequence |
GPLGSMSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSMLVDKYIFRILSIPS
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains.
pubmed doi rcsb |
| molecule tags |
Lyase
|
| source organism |
Homo sapiens
|
| molecule keywords |
Aprataxin and PNK-like factor
|
| total genus |
16
|
| structure length |
110
|
| sequence length |
110
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase. |
| pdb deposition date | 2015-10-07 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF17913 | FHA_2 | FHA domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Sandwich | Tumour Suppressor Smad4 | Tumour Suppressor Smad4 |
#chains in the Genus database with same CATH superfamily 5E50 A; 3VA1 A; 1K2N A; 3I0M A; 2AFF A; 3I6W A; 2XT9 B; 2KFU A; 1J4L A; 3UN0 A; 1FHQ A; 3VA4 A; 5DJO A; 2CSW A; 2JPE A; 1J4K A; 3HX1 A; 1J4P A; 3GQS A; 1GXC A; 2KB4 A; 1UHT A; 2G1L A; 3ELS A; 2JQI A; 1LGP A; 3HUF A; 2PIE A; 1K3N A; 4EGX A; 1LGQ A; 2W3O A; 4D9V A; 3I0N A; 4A0E A; 1J4O A; 1QU5 A; 3PO8 A; 1WLN A; 2JKD A; 2KKL A; 3HUE A; 2BRF A; 4H87 A; 1G6G A; 4QCJ A; 3FM8 A; 3I6U A; 1K3J A; 1WV3 A; 3KT9 A; 1FHR A; 1G3G A; 1K3Q A; 2LC1 A; 1J4Q A; 2JQL A; 3OUN A; 5A8I A; 1DMZ A; 4G2S A; 1K2M A; 3UOT A; 2FF4 A; 2A0T A; 3UMZ A; 1R21 A; 1YJM A; 2KB3 A; 2FEZ A; 3VPY A; 1YJ5 C; 2EH0 A; 3MDB A; 3UNM A; 3POA A; 1UJX A; 4EJQ A; 3UV0 A; 2JQJ A; 4JON A; 1MZK A; 3UNN A; 3ELV A; #chains in the Genus database with same CATH topology 2Q5F A; 5E50 A; 1YGS A; 3VA1 A; 1K2N A; 1U7F B; 3I0M A; 3VZC A; 5EJG A; 5BVI A; 2AFF A; 5DHQ A; 4V24 A; 3GMJ A; 3I6W A; 3A77 A; 3VZB A; 2XT9 B; 1U7F A; 2KFU A; 1J4L A; 3UN0 A; 1FHQ A; 3VA4 A; 5DJO A; 5DHS A; 2CSW A; 2JPE A; 2QV7 A; 3V8R A; 4DY6 A; 1J4K A; 3HX1 A; 1J4P A; 3V8Q A; 3GQS A; 5EJI A; 2KB4 A; 1UHT A; 1GXC A; 2G1L A; 1DEV A; 3ELS A; 2JQI A; 1LGP A; 4JON A; 3VZD A; 1U7V B; 1U0T A; 3DIT A; 4R9P A; 2BON A; 3HUF A; 3S40 A; 1MK2 A; 4HAO A; 2PIE A; 1K3N A; 4EGX A; 5DHP A; 1DD1 A; 1LGQ A; 1Z0Z A; 5DHT A; 3V80 A; 3V7Y A; 5JEO A; 3DSH A; 2W3O A; 4D9V A; 5JEL A; 3I0N A; 4A0E A; 1J4O A; 1Y3H A; 1MR1 A; 5DHU A; 5DHR A; 1QU5 A; 4KU0 D; 3PO8 A; 1WLN A; 2JKD A; 2KKL A; 3V7W A; 3HUE A; 2BRF A; 1YT5 A; 5JEK A; 1Y3I A; 4WER A; 4H87 A; 1G6G A; 3AFO A; 4QCJ A; 3FM8 A; 2XXS A; 3I6U A; 5JEJ A; 1K3J A; 1WV3 A; 4JIV D; 1U0R A; 2I2F A; 3KT9 A; 1FHR A; 1G3G A; 1J2F A; 1K3Q A; 2I1W A; 2LC1 A; 1J4Q A; 4A4Y A; 4JIW D; 1U7V A; 1MJS A; 2JQL A; 5C4V A; 3OUN A; 5A8I A; 1QWT A; 1KHX A; 1Z0U A; 1DMZ A; 2JGR A; 1G88 A; 2I2C A; 4G2S A; 1K2M A; 5JER A; 3UOT A; 2FF4 A; 2A0T A; 5JEM A; 3V7U A; 4WRR A; 2I2A A; 5EJH A; 3UMZ A; 1R21 A; 2I2B A; 3V8P A; 2P1R A; 1YJM A; 2KB3 A; 2I29 A; 3T5P A; 2FEZ A; 2I2D A; 3V8M A; 2QVL A; 5EJF A; 3VPY A; 2AN1 A; 1YJ5 C; 3MDB A; 3PFN A; 3UNM A; 3POA A; 1UJX A; 4EJQ A; 4L02 A; 3V8N A; 1SUW A; 1KHU A; 3UV0 A; 2JQJ A; 1ZOQ A; 2EH0 A; 1MZK A; 1Z0S A; 3UNN A; 3ELV A; #chains in the Genus database with same CATH homology 5E50 A; 1YGS A; 3VA1 A; 1K2N A; 1U7F B; 3I0M A; 3VZC A; 5BVI A; 2AFF A; 4V24 A; 3GMJ A; 3I6W A; 3A77 A; 3VZB A; 2XT9 B; 1U7F A; 2KFU A; 1J4L A; 3UN0 A; 1FHQ A; 3VA4 A; 5DJO A; 2CSW A; 2JPE A; 2QV7 A; 1J4K A; 3HX1 A; 1J4P A; 3GQS A; 2KB4 A; 1UHT A; 1GXC A; 2G1L A; 1DEV A; 3ELS A; 2JQI A; 1LGP A; 4JON A; 3VZD A; 1U7V B; 3DIT A; 4R9P A; 2BON A; 3HUF A; 3S40 A; 1MK2 A; 2PIE A; 1K3N A; 4EGX A; 1DD1 A; 1LGQ A; 5JEO A; 3DSH A; 2W3O A; 4D9V A; 5JEL A; 3I0N A; 4A0E A; 1J4O A; 1MR1 A; 1QU5 A; 4KU0 D; 3PO8 A; 1WLN A; 2JKD A; 2KKL A; 3HUE A; 2BRF A; 5JEK A; 4WER A; 4H87 A; 1G6G A; 4QCJ A; 3FM8 A; 2XXS A; 3I6U A; 5JEJ A; 1K3J A; 1WV3 A; 4JIV D; 3KT9 A; 1FHR A; 1G3G A; 1J2F A; 1K3Q A; 2LC1 A; 1J4Q A; 4A4Y A; 4JIW D; 1U7V A; 1MJS A; 2JQL A; 5C4V A; 3OUN A; 5A8I A; 1QWT A; 1KHX A; 1DMZ A; 2JGR A; 1G88 A; 4G2S A; 1K2M A; 5JER A; 3UOT A; 2FF4 A; 2A0T A; 5JEM A; 4WRR A; 3UMZ A; 1R21 A; 2P1R A; 1YJM A; 2KB3 A; 3T5P A; 2FEZ A; 2QVL A; 3VPY A; 1YJ5 C; 3MDB A; 3UNM A; 3POA A; 1UJX A; 4EJQ A; 4L02 A; 3UV0 A; 1KHU A; 2JQJ A; 1ZOQ A; 2EH0 A; 1MZK A; 3UNN A; 3ELV A;
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