1PVMA

Crystal structure of a conserved cbs domain protein ta0289 of unknown function from thermoplasma acidophilum
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
178
structure length
178
Chain Sequence
MFMRVEKIMNSNFKTVNWNTTVFDAVKIMNENHLYGLVVKDDNGNDVGLLSERSIIKRFIPRNKKPDEVPIRLVMRKPIPKVKSDYDVKDVAAYLSENGLERCAVVDDPGRVVGIVTLTDLSRYLSRASITDILLSHRTKDYQHLCPKCGVGVLEPVYNEKGEIKVFRCSNPACDYEE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain
pubmed doi rcsb
molecule tags Structural genomics, unknown function
source organism Thermoplasma acidophilum dsm 1728
molecule keywords conserved hypothetical protein Ta0289
total genus 50
structure length 178
sequence length 178
chains with identical sequence B
ec nomenclature
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
A PF09151 DUF1936 Domain of unknown function (DUF1936)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 1pvmA00
3K2VA 3KH5A 3FHMA 3L2BA 4HG0A 3PC3A 2YZIA 3PC4A 4L0DA 4COOA 2EF7A 2OOYE 3L31A 4O9KA 3DDJA 2EMQA 2QRDE 2RC3A 2RIFA 2QH1A 1PBJA 2D4ZA 5K25C 3FWSA 4FXSA 1Y5HA 5MMZA 2UV6A 3KPBA 3K6EA 5K24C 3T4NC 4IYSA 4P1OA 2YVZA 5LXQA 3I8NA 2PFIA 5KS7A 2RIHA 1YAVA 3HF7A 3ORGA 2YVYA 3GBYA 3LHHA 4GQYA 5IIPA 2ZY9A 4ESYA 4IY2A 4P1GA 2UV7A 1XKFA 2QRCE 2QREE 3PC2A 4L3VA 2NYCA 3OCOA 2OOXE 4DQWA 1O50A 3TE5C 3KPDA 3OI8A 3TDHC 3LFZA 4L27A 2P9MA 3KXRA 4UUUA 2YVXA 4GQVA 2YZQA 4PCUA 3FV6A 3KPCA 2O16A 4NOCA 4IY0A 3FNAA 3OCMA 2OUXA 4FRYA 2QLVC 3FWRA 1PVMA 2QR1E 4IY4A 3LV9A 5K23C 3SL7A 2NYEA 4ESYB 5K22B 2UV5A 4IY3A 4GQWA 2UV4A 3LQNA 4L28A
chains in the Genus database with same CATH superfamily
3K2VA 3KH5A 3FHMA 3L2BA 4HG0A 3PC3A 2YZIA 3PC4A 4L0DA 4COOA 2EF7A 2OOYE 3L31A 4O9KA 3DDJA 2EMQA 2QRDE 2RC3A 2RIFA 2QH1A 1PBJA 2D4ZA 5K25C 3FWSA 4FXSA 1Y5HA 5MMZA 2UV6A 3KPBA 3K6EA 2JA3A 5K24C 3T4NC 4IYSA 4P1OA 2YVZA 5LXQA 3I8NA 2PFIA 5KS7A 2RIHA 1YAVA 3HF7A 3ORGA 2YVYA 3GBYA 3LHHA 4GQYA 5IIPA 2ZY9A 4ESYA 4IY2A 4P1GA 2UV7A 1XKFA 2QRCE 2QREE 3PC2A 4L3VA 2NYCA 3OCOA 2OOXE 4DQWA 1O50A 3TE5C 2J9LA 3KPDA 3OI8A 3TDHC 3LFZA 4L27A 2P9MA 3KXRA 4UUUA 2YVXA 4GQVA 2YZQA 4PCUA 3FV6A 3KPCA 2O16A 4NOCA 4IY0A 3FNAA 3OCMA 2OUXA 4FRYA 2QLVC 3FWRA 1PVMA 2QR1E 4IY4A 3LV9A 5K23C 3SL7A 2NYEA 4ESYB 5K22B 2UV5A 4IY3A 4GQWA 2UV4A 3LQNA 4L28A
chains in the Genus database with same CATH topology
3K2VA 3KH5A 3FHMA 3L2BA 4HG0A 3PC3A 2YZIA 3PC4A 4L0DA 4COOA 2EF7A 2OOYE 3L31A 4O9KA 3DDJA 2EMQA 2QRDE 2RC3A 2RIFA 2QH1A 1PBJA 2D4ZA 5K25C 3FWSA 4FXSA 1Y5HA 5MMZA 2UV6A 3KPBA 3K6EA 2JA3A 5K24C 3T4NC 4IYSA 4P1OA 2YVZA 5LXQA 3I8NA 2PFIA 5KS7A 2RIHA 1YAVA 3HF7A 3ORGA 2YVYA 3GBYA 3LHHA 4GQYA 5IIPA 2ZY9A 4ESYA 4IY2A 4P1GA 2UV7A 1XKFA 2QRCE 2QREE 3PC2A 4L3VA 2NYCA 3OCOA 2OOXE 4DQWA 1O50A 3TE5C 2J9LA 3KPDA 3OI8A 3TDHC 3LFZA 4L27A 2P9MA 3KXRA 4UUUA 2YVXA 4GQVA 2YZQA 4PCUA 3FV6A 3KPCA 2O16A 4NOCA 4IY0A 3FNAA 3OCMA 2OUXA 4FRYA 2QLVC 3FWRA 1PVMA 2QR1E 4IY4A 3LV9A 5K23C 3SL7A 2NYEA 4ESYB 5K22B 2UV5A 4IY3A 4GQWA 2UV4A 3LQNA 4L28A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K2V A;  3KH5 A;  3FHM A;  3L2B A;  4HG0 A;  3PC3 A;  2YZI A;  3PC4 A;  4L0D A;  4COO A;  2EF7 A;  2OOY E;  3L31 A;  4O9K A;  3DDJ A;  2EMQ A;  2QRD E;  2RC3 A;  2RIF A;  2QH1 A;  1PBJ A;  2D4Z A;  5K25 C;  3FWS A;  4FXS A;  1Y5H A;  5MMZ A;  2UV6 A;  3KPB A;  3K6E A;  5K24 C;  3T4N C;  4IYS A;  4P1O A;  2YVZ A;  5LXQ A;  3I8N A;  2PFI A;  5KS7 A;  2RIH A;  1YAV A;  3HF7 A;  3ORG A;  2YVY A;  3GBY A;  3LHH A;  4GQY A;  5IIP A;  2ZY9 A;  4ESY A;  4IY2 A;  4P1G A;  2UV7 A;  1XKF A;  2QRC E;  2QRE E;  3PC2 A;  4L3V A;  2NYC A;  3OCO A;  2OOX E;  4DQW A;  1O50 A;  3TE5 C;  3KPD A;  3OI8 A;  3TDH C;  3LFZ A;  4L27 A;  2P9M A;  3KXR A;  4UUU A;  2YVX A;  4GQV A;  2YZQ A;  4PCU A;  3FV6 A;  3KPC A;  2O16 A;  4NOC A;  4IY0 A;  3FNA A;  3OCM A;  2OUX A;  4FRY A;  2QLV C;  3FWR A;  1PVM A;  2QR1 E;  4IY4 A;  3LV9 A;  5K23 C;  3SL7 A;  2NYE A;  4ESY B;  5K22 B;  2UV5 A;  4IY3 A;  4GQW A;  2UV4 A;  3LQN A;  4L28 A; 
#chains in the Genus database with same CATH topology
 3K2V A;  3KH5 A;  3FHM A;  3L2B A;  4HG0 A;  3PC3 A;  2YZI A;  3PC4 A;  4L0D A;  4COO A;  2EF7 A;  2OOY E;  3L31 A;  4O9K A;  3DDJ A;  2EMQ A;  2QRD E;  2RC3 A;  2RIF A;  2QH1 A;  1PBJ A;  2D4Z A;  5K25 C;  3FWS A;  4FXS A;  1Y5H A;  5MMZ A;  2UV6 A;  3KPB A;  3K6E A;  2JA3 A;  5K24 C;  3T4N C;  4IYS A;  4P1O A;  2YVZ A;  5LXQ A;  3I8N A;  2PFI A;  5KS7 A;  2RIH A;  1YAV A;  3HF7 A;  3ORG A;  2YVY A;  3GBY A;  3LHH A;  4GQY A;  5IIP A;  2ZY9 A;  4ESY A;  4IY2 A;  4P1G A;  2UV7 A;  1XKF A;  2QRC E;  2QRE E;  3PC2 A;  4L3V A;  2NYC A;  3OCO A;  2OOX E;  4DQW A;  1O50 A;  3TE5 C;  2J9L A;  3KPD A;  3OI8 A;  3TDH C;  3LFZ A;  4L27 A;  2P9M A;  3KXR A;  4UUU A;  2YVX A;  4GQV A;  2YZQ A;  4PCU A;  3FV6 A;  3KPC A;  2O16 A;  4NOC A;  4IY0 A;  3FNA A;  3OCM A;  2OUX A;  4FRY A;  2QLV C;  3FWR A;  1PVM A;  2QR1 E;  4IY4 A;  3LV9 A;  5K23 C;  3SL7 A;  2NYE A;  4ESY B;  5K22 B;  2UV5 A;  4IY3 A;  4GQW A;  2UV4 A;  3LQN A;  4L28 A; 
#chains in the Genus database with same CATH homology
 3K2V A;  3KH5 A;  3FHM A;  3L2B A;  4HG0 A;  3PC3 A;  2YZI A;  3PC4 A;  4L0D A;  4COO A;  2EF7 A;  2OOY E;  3L31 A;  4O9K A;  3DDJ A;  2EMQ A;  2QRD E;  2RC3 A;  2RIF A;  2QH1 A;  1PBJ A;  2D4Z A;  5K25 C;  3FWS A;  4FXS A;  1Y5H A;  5MMZ A;  2UV6 A;  3KPB A;  3K6E A;  2JA3 A;  5K24 C;  3T4N C;  4IYS A;  4P1O A;  2YVZ A;  5LXQ A;  3I8N A;  2PFI A;  5KS7 A;  2RIH A;  1YAV A;  3HF7 A;  3ORG A;  2YVY A;  3GBY A;  3LHH A;  4GQY A;  5IIP A;  2ZY9 A;  4ESY A;  4IY2 A;  4P1G A;  2UV7 A;  1XKF A;  2QRC E;  2QRE E;  3PC2 A;  4L3V A;  2NYC A;  3OCO A;  2OOX E;  4DQW A;  1O50 A;  3TE5 C;  2J9L A;  3KPD A;  3OI8 A;  3TDH C;  3LFZ A;  4L27 A;  2P9M A;  3KXR A;  4UUU A;  2YVX A;  4GQV A;  2YZQ A;  4PCU A;  3FV6 A;  3KPC A;  2O16 A;  4NOC A;  4IY0 A;  3FNA A;  3OCM A;  2OUX A;  4FRY A;  2QLV C;  3FWR A;  1PVM A;  2QR1 E;  4IY4 A;  3LV9 A;  5K23 C;  3SL7 A;  2NYE A;  4ESY B;  5K22 B;  2UV5 A;  4IY3 A;  4GQW A;  2UV4 A;  3LQN A;  4L28 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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