1XKFA

Crystal structure of hypoxic response protein i (hrpi) with two coordinated zinc ions
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
123
structure length
120
Chain Sequence
TTARDIMNAGVTCVGEHETLTAAAQYMREHDIGALPICGDDDRLHGMLTDRDIVIKGLAAGLDPNTATAGELAIYYVDANASIQEMLNVMEEHQVRRVPVISEHRLVGIVTEADIARHLP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure and unusual protein chemistry of hypoxic response protein 1, a latency antigen and highly expressed member of the DosR regulon in Mycobacterium tuberculosis
pubmed doi rcsb
molecule tags Unknown function
source organism Mycobacterium tuberculosis
molecule keywords hypothetical protein RV2626C
total genus 34
structure length 120
sequence length 123
chains with identical sequence B
ec nomenclature
pdb deposition date 2004-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 1xkfA00
2YVYA 2EF7A 3KXRA 3LV9A 3KH5A 1PVMA 5K25C 2PFIA 2O16A 4FXSA 2YVZA 4ESYA 3L2BA 3L31A 2OOYE 3FWRA 4L0DA 5K22B 2YZIA 2ZY9A 4DQWA 3PC2A 5KS7A 3TE5C 2QR1E 3DDJA 1XKFA 3FWSA 4IY2A 4IY3A 2NYEA 4L27A 2D4ZA 2YZQA 2QRDE 2UV5A 3SL7A 3LHHA 4NOCA 4L28A 2UV6A 4PCUA 2YVXA 4GQVA 1YAVA 4L3VA 3TDHC 3FV6A 2QLVC 3PC3A 5K23C 2EMQA 3LQNA 4GQWA 2QRCE 5IIPA 4IYSA 3T4NC 2QH1A 4P1GA 3K6EA 3FNAA 4P1OA 5LXQA 3KPCA 3PC4A 1PBJA 2RC3A 3KPDA 2UV7A 3I8NA 4COOA 2RIHA 3K2VA 2OUXA 4GQYA 3KPBA 4FRYA 4ESYB 5K24C 3HF7A 2P9MA 1Y5HA 4UUUA 4HG0A 2NYCA 1O50A 3GBYA 3LFZA 3ORGA 3OCMA 2QREE 3FHMA 4IY0A 2UV4A 2OOXE 3OCOA 3OI8A 2RIFA 5MMZA 4IY4A 4O9KA
chains in the Genus database with same CATH superfamily
2YVYA 2EF7A 3KXRA 3LV9A 3KH5A 1PVMA 5K25C 2PFIA 2O16A 4FXSA 2YVZA 2JA3A 4ESYA 3L2BA 3L31A 2OOYE 3FWRA 4L0DA 5K22B 2YZIA 2ZY9A 4DQWA 3PC2A 5KS7A 3TE5C 2QR1E 3DDJA 1XKFA 3FWSA 4IY2A 4IY3A 2NYEA 4L27A 2D4ZA 2YZQA 2QRDE 2UV5A 3SL7A 3LHHA 4NOCA 4L28A 2UV6A 4PCUA 2YVXA 4GQVA 1YAVA 4L3VA 3TDHC 3FV6A 2QLVC 3PC3A 5K23C 2EMQA 3LQNA 4GQWA 2QRCE 5IIPA 4IYSA 3T4NC 2QH1A 4P1GA 3K6EA 3FNAA 4P1OA 5LXQA 3KPCA 3PC4A 1PBJA 2RC3A 3KPDA 2UV7A 3I8NA 4COOA 2RIHA 3K2VA 2OUXA 2J9LA 3KPBA 4GQYA 4FRYA 4ESYB 5K24C 3HF7A 2P9MA 1Y5HA 4UUUA 4HG0A 2NYCA 1O50A 3GBYA 3LFZA 3ORGA 3OCMA 2QREE 3FHMA 4IY0A 2UV4A 2OOXE 3OCOA 3OI8A 2RIFA 5MMZA 4IY4A 4O9KA
chains in the Genus database with same CATH topology
2YVYA 2EF7A 3KXRA 3LV9A 3KH5A 1PVMA 5K25C 2PFIA 2O16A 4FXSA 2YVZA 2JA3A 4ESYA 3L2BA 3L31A 2OOYE 3FWRA 4L0DA 5K22B 2YZIA 2ZY9A 4DQWA 3PC2A 5KS7A 3TE5C 2QR1E 3DDJA 1XKFA 3FWSA 4IY2A 4IY3A 2NYEA 4L27A 2D4ZA 2YZQA 2QRDE 2UV5A 3SL7A 3LHHA 4NOCA 4L28A 2UV6A 4PCUA 2YVXA 4GQVA 1YAVA 4L3VA 3TDHC 3FV6A 2QLVC 3PC3A 5K23C 2EMQA 3LQNA 4GQWA 2QRCE 5IIPA 4IYSA 3T4NC 2QH1A 4P1GA 3K6EA 3FNAA 4P1OA 5LXQA 3KPCA 3PC4A 1PBJA 2RC3A 3KPDA 2UV7A 3I8NA 4COOA 2RIHA 3K2VA 2OUXA 2J9LA 3KPBA 4GQYA 4FRYA 4ESYB 5K24C 3HF7A 2P9MA 1Y5HA 4UUUA 4HG0A 2NYCA 1O50A 3GBYA 3LFZA 3ORGA 3OCMA 2QREE 3FHMA 4IY0A 2UV4A 2OOXE 3OCOA 3OI8A 2RIFA 5MMZA 4IY4A 4O9KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YVY A;  2EF7 A;  3KXR A;  3LV9 A;  3KH5 A;  1PVM A;  5K25 C;  2PFI A;  2O16 A;  4FXS A;  2YVZ A;  4ESY A;  3L2B A;  3L31 A;  2OOY E;  3FWR A;  4L0D A;  5K22 B;  2YZI A;  2ZY9 A;  4DQW A;  3PC2 A;  5KS7 A;  3TE5 C;  2QR1 E;  3DDJ A;  1XKF A;  3FWS A;  4IY2 A;  4IY3 A;  2NYE A;  4L27 A;  2D4Z A;  2YZQ A;  2QRD E;  2UV5 A;  3SL7 A;  3LHH A;  4NOC A;  4L28 A;  2UV6 A;  4PCU A;  2YVX A;  4GQV A;  1YAV A;  4L3V A;  3TDH C;  3FV6 A;  2QLV C;  3PC3 A;  5K23 C;  2EMQ A;  3LQN A;  4GQW A;  2QRC E;  5IIP A;  4IYS A;  3T4N C;  2QH1 A;  4P1G A;  3K6E A;  3FNA A;  4P1O A;  5LXQ A;  3KPC A;  3PC4 A;  1PBJ A;  2RC3 A;  3KPD A;  2UV7 A;  3I8N A;  4COO A;  2RIH A;  3K2V A;  2OUX A;  4GQY A;  3KPB A;  4FRY A;  4ESY B;  5K24 C;  3HF7 A;  2P9M A;  1Y5H A;  4UUU A;  4HG0 A;  2NYC A;  1O50 A;  3GBY A;  3LFZ A;  3ORG A;  3OCM A;  2QRE E;  3FHM A;  4IY0 A;  2UV4 A;  2OOX E;  3OCO A;  3OI8 A;  2RIF A;  5MMZ A;  4IY4 A;  4O9K A; 
#chains in the Genus database with same CATH topology
 2YVY A;  2EF7 A;  3KXR A;  3LV9 A;  3KH5 A;  1PVM A;  5K25 C;  2PFI A;  2O16 A;  4FXS A;  2YVZ A;  2JA3 A;  4ESY A;  3L2B A;  3L31 A;  2OOY E;  3FWR A;  4L0D A;  5K22 B;  2YZI A;  2ZY9 A;  4DQW A;  3PC2 A;  5KS7 A;  3TE5 C;  2QR1 E;  3DDJ A;  1XKF A;  3FWS A;  4IY2 A;  4IY3 A;  2NYE A;  4L27 A;  2D4Z A;  2YZQ A;  2QRD E;  2UV5 A;  3SL7 A;  3LHH A;  4NOC A;  4L28 A;  2UV6 A;  4PCU A;  2YVX A;  4GQV A;  1YAV A;  4L3V A;  3TDH C;  3FV6 A;  2QLV C;  3PC3 A;  5K23 C;  2EMQ A;  3LQN A;  4GQW A;  2QRC E;  5IIP A;  4IYS A;  3T4N C;  2QH1 A;  4P1G A;  3K6E A;  3FNA A;  4P1O A;  5LXQ A;  3KPC A;  3PC4 A;  1PBJ A;  2RC3 A;  3KPD A;  2UV7 A;  3I8N A;  4COO A;  2RIH A;  3K2V A;  2OUX A;  2J9L A;  3KPB A;  4GQY A;  4FRY A;  4ESY B;  5K24 C;  3HF7 A;  2P9M A;  1Y5H A;  4UUU A;  4HG0 A;  2NYC A;  1O50 A;  3GBY A;  3LFZ A;  3ORG A;  3OCM A;  2QRE E;  3FHM A;  4IY0 A;  2UV4 A;  2OOX E;  3OCO A;  3OI8 A;  2RIF A;  5MMZ A;  4IY4 A;  4O9K A; 
#chains in the Genus database with same CATH homology
 2YVY A;  2EF7 A;  3KXR A;  3LV9 A;  3KH5 A;  1PVM A;  5K25 C;  2PFI A;  2O16 A;  4FXS A;  2YVZ A;  2JA3 A;  4ESY A;  3L2B A;  3L31 A;  2OOY E;  3FWR A;  4L0D A;  5K22 B;  2YZI A;  2ZY9 A;  4DQW A;  3PC2 A;  5KS7 A;  3TE5 C;  2QR1 E;  3DDJ A;  1XKF A;  3FWS A;  4IY2 A;  4IY3 A;  2NYE A;  4L27 A;  2D4Z A;  2YZQ A;  2QRD E;  2UV5 A;  3SL7 A;  3LHH A;  4NOC A;  4L28 A;  2UV6 A;  4PCU A;  2YVX A;  4GQV A;  1YAV A;  4L3V A;  3TDH C;  3FV6 A;  2QLV C;  3PC3 A;  5K23 C;  2EMQ A;  3LQN A;  4GQW A;  2QRC E;  5IIP A;  4IYS A;  3T4N C;  2QH1 A;  4P1G A;  3K6E A;  3FNA A;  4P1O A;  5LXQ A;  3KPC A;  3PC4 A;  1PBJ A;  2RC3 A;  3KPD A;  2UV7 A;  3I8N A;  4COO A;  2RIH A;  3K2V A;  2OUX A;  2J9L A;  3KPB A;  4GQY A;  4FRY A;  4ESY B;  5K24 C;  3HF7 A;  2P9M A;  1Y5H A;  4UUU A;  4HG0 A;  2NYC A;  1O50 A;  3GBY A;  3LFZ A;  3ORG A;  3OCM A;  2QRE E;  3FHM A;  4IY0 A;  2UV4 A;  2OOX E;  3OCO A;  3OI8 A;  2RIF A;  5MMZ A;  4IY4 A;  4O9K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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