2D4ZA

Crystal structure of the cytoplasmic domain of the chloride channel clc-0
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
244
structure length
169
Chain Sequence
LSWSSANKYNIQVGDIMVRDVTSIASTSTYGDLLHVLRQTKLKFFPFVDTPDTNTLLGSIDRTEVEGLLQRRISAYRRQPAAAAEADEEFEEMLTLEEIYRWEQREKNVVVNFETCRIDQSPFQLVEGTSLQKTHTLFSLLGLDRAYVTSMGKLVGVVALAEIQAAIEG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of the cytoplasmic domain of the chloride channel ClC-0.
pubmed doi rcsb
molecule tags Transport protein
source organism Torpedo marmorata
molecule keywords Chloride channel protein
total genus 34
structure length 169
sequence length 244
chains with identical sequence B
ec nomenclature
pdb deposition date 2005-10-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2d4zA00
2P9MA 5LXQA 4IY4A 3FV6A 2UV6A 4IY3A 2PFIA 1PVMA 2YZQA 3OCOA 3OI8A 2RIFA 4UUUA 2ZY9A 3FHMA 2YVXA 3K6EA 1XKFA 3PC4A 4IY2A 4L27A 2QREE 3K2VA 3LV9A 2YVZA 3SL7A 2EMQA 5MMZA 3FNAA 3PC2A 4GQYA 3OCMA 2QLVC 3FWSA 2UV4A 3ORGA 2QRCE 4HG0A 2O16A 2NYEA 4P1GA 4GQVA 1YAVA 2D4ZA 2QH1A 4IY0A 3L2BA 4FXSA 4ESYB 4PCUA 3LFZA 3GBYA 4NOCA 3LQNA 4L0DA 3T4NC 2OOYE 3TE5C 5K23C 4DQWA 3KPBA 4P1OA 2RC3A 3KXRA 3KPCA 4COOA 4IYSA 4O9KA 3HF7A 1O50A 2UV7A 3FWRA 4GQWA 5KS7A 2NYCA 2QRDE 5K22B 2EF7A 5IIPA 3TDHC 1Y5HA 2OUXA 2RIHA 2YVYA 3KPDA 3L31A 2QR1E 3LHHA 4ESYA 4L28A 3PC3A 2UV5A 2OOXE 1PBJA 3KH5A 4L3VA 5K24C 5K25C 4FRYA 3I8NA 3DDJA 2YZIA
chains in the Genus database with same CATH superfamily
2P9MA 5LXQA 4IY4A 3FV6A 2UV6A 4IY3A 2PFIA 1PVMA 2YZQA 3OCOA 3OI8A 2RIFA 4UUUA 2ZY9A 3FHMA 2YVXA 3K6EA 1XKFA 3PC4A 4IY2A 4L27A 2QREE 3K2VA 3LV9A 2YVZA 3SL7A 2EMQA 5MMZA 3FNAA 3PC2A 4GQYA 3OCMA 2QLVC 3FWSA 2UV4A 3ORGA 2QRCE 4HG0A 2O16A 2NYEA 4P1GA 4GQVA 1YAVA 2D4ZA 2QH1A 4IY0A 3L2BA 4FXSA 4ESYB 4PCUA 3LFZA 3GBYA 4NOCA 3LQNA 4L0DA 3T4NC 2OOYE 3TE5C 5K23C 4DQWA 3KPBA 2J9LA 4P1OA 2RC3A 3KXRA 3KPCA 4COOA 4IYSA 4O9KA 3HF7A 1O50A 2UV7A 2JA3A 3FWRA 4GQWA 5KS7A 2NYCA 2QRDE 5K22B 2EF7A 5IIPA 3TDHC 1Y5HA 2OUXA 2RIHA 2YVYA 3KPDA 3L31A 2QR1E 3LHHA 4ESYA 4L28A 3PC3A 2UV5A 2OOXE 1PBJA 3KH5A 4L3VA 5K24C 5K25C 4FRYA 3I8NA 3DDJA 2YZIA
chains in the Genus database with same CATH topology
2P9MA 5LXQA 4IY4A 3FV6A 2UV6A 4IY3A 2PFIA 1PVMA 2YZQA 3OCOA 3OI8A 2RIFA 4UUUA 2ZY9A 3FHMA 2YVXA 3K6EA 1XKFA 3PC4A 4IY2A 4L27A 2QREE 3K2VA 3LV9A 2YVZA 3SL7A 2EMQA 5MMZA 3FNAA 3PC2A 4GQYA 3OCMA 2QLVC 3FWSA 2UV4A 3ORGA 2QRCE 4HG0A 2O16A 2NYEA 4P1GA 4GQVA 1YAVA 2D4ZA 2QH1A 4IY0A 3L2BA 4FXSA 4ESYB 4PCUA 3LFZA 3GBYA 4NOCA 3LQNA 4L0DA 3T4NC 2OOYE 3TE5C 5K23C 4DQWA 3KPBA 2J9LA 4P1OA 2RC3A 3KXRA 3KPCA 4COOA 4IYSA 4O9KA 3HF7A 1O50A 2UV7A 2JA3A 3FWRA 4GQWA 5KS7A 2NYCA 2QRDE 5K22B 2EF7A 5IIPA 3TDHC 1Y5HA 2OUXA 2RIHA 2YVYA 3KPDA 3L31A 2QR1E 3LHHA 4ESYA 4L28A 3PC3A 2UV5A 2OOXE 1PBJA 3KH5A 4L3VA 5K24C 5K25C 4FRYA 3I8NA 3DDJA 2YZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P9M A;  5LXQ A;  4IY4 A;  3FV6 A;  2UV6 A;  4IY3 A;  2PFI A;  1PVM A;  2YZQ A;  3OCO A;  3OI8 A;  2RIF A;  4UUU A;  2ZY9 A;  3FHM A;  2YVX A;  3K6E A;  1XKF A;  3PC4 A;  4IY2 A;  4L27 A;  2QRE E;  3K2V A;  3LV9 A;  2YVZ A;  3SL7 A;  2EMQ A;  5MMZ A;  3FNA A;  3PC2 A;  4GQY A;  3OCM A;  2QLV C;  3FWS A;  2UV4 A;  3ORG A;  2QRC E;  4HG0 A;  2O16 A;  2NYE A;  4P1G A;  4GQV A;  1YAV A;  2D4Z A;  2QH1 A;  4IY0 A;  3L2B A;  4FXS A;  4ESY B;  4PCU A;  3LFZ A;  3GBY A;  4NOC A;  3LQN A;  4L0D A;  3T4N C;  2OOY E;  3TE5 C;  5K23 C;  4DQW A;  3KPB A;  4P1O A;  2RC3 A;  3KXR A;  3KPC A;  4COO A;  4IYS A;  4O9K A;  3HF7 A;  1O50 A;  2UV7 A;  3FWR A;  4GQW A;  5KS7 A;  2NYC A;  2QRD E;  5K22 B;  2EF7 A;  5IIP A;  3TDH C;  1Y5H A;  2OUX A;  2RIH A;  2YVY A;  3KPD A;  3L31 A;  2QR1 E;  3LHH A;  4ESY A;  4L28 A;  3PC3 A;  2UV5 A;  2OOX E;  1PBJ A;  3KH5 A;  4L3V A;  5K24 C;  5K25 C;  4FRY A;  3I8N A;  3DDJ A;  2YZI A; 
#chains in the Genus database with same CATH topology
 2P9M A;  5LXQ A;  4IY4 A;  3FV6 A;  2UV6 A;  4IY3 A;  2PFI A;  1PVM A;  2YZQ A;  3OCO A;  3OI8 A;  2RIF A;  4UUU A;  2ZY9 A;  3FHM A;  2YVX A;  3K6E A;  1XKF A;  3PC4 A;  4IY2 A;  4L27 A;  2QRE E;  3K2V A;  3LV9 A;  2YVZ A;  3SL7 A;  2EMQ A;  5MMZ A;  3FNA A;  3PC2 A;  4GQY A;  3OCM A;  2QLV C;  3FWS A;  2UV4 A;  3ORG A;  2QRC E;  4HG0 A;  2O16 A;  2NYE A;  4P1G A;  4GQV A;  1YAV A;  2D4Z A;  2QH1 A;  4IY0 A;  3L2B A;  4FXS A;  4ESY B;  4PCU A;  3LFZ A;  3GBY A;  4NOC A;  3LQN A;  4L0D A;  3T4N C;  2OOY E;  3TE5 C;  5K23 C;  4DQW A;  3KPB A;  2J9L A;  4P1O A;  2RC3 A;  3KXR A;  3KPC A;  4COO A;  4IYS A;  4O9K A;  3HF7 A;  1O50 A;  2UV7 A;  2JA3 A;  3FWR A;  4GQW A;  5KS7 A;  2NYC A;  2QRD E;  5K22 B;  2EF7 A;  5IIP A;  3TDH C;  1Y5H A;  2OUX A;  2RIH A;  2YVY A;  3KPD A;  3L31 A;  2QR1 E;  3LHH A;  4ESY A;  4L28 A;  3PC3 A;  2UV5 A;  2OOX E;  1PBJ A;  3KH5 A;  4L3V A;  5K24 C;  5K25 C;  4FRY A;  3I8N A;  3DDJ A;  2YZI A; 
#chains in the Genus database with same CATH homology
 2P9M A;  5LXQ A;  4IY4 A;  3FV6 A;  2UV6 A;  4IY3 A;  2PFI A;  1PVM A;  2YZQ A;  3OCO A;  3OI8 A;  2RIF A;  4UUU A;  2ZY9 A;  3FHM A;  2YVX A;  3K6E A;  1XKF A;  3PC4 A;  4IY2 A;  4L27 A;  2QRE E;  3K2V A;  3LV9 A;  2YVZ A;  3SL7 A;  2EMQ A;  5MMZ A;  3FNA A;  3PC2 A;  4GQY A;  3OCM A;  2QLV C;  3FWS A;  2UV4 A;  3ORG A;  2QRC E;  4HG0 A;  2O16 A;  2NYE A;  4P1G A;  4GQV A;  1YAV A;  2D4Z A;  2QH1 A;  4IY0 A;  3L2B A;  4FXS A;  4ESY B;  4PCU A;  3LFZ A;  3GBY A;  4NOC A;  3LQN A;  4L0D A;  3T4N C;  2OOY E;  3TE5 C;  5K23 C;  4DQW A;  3KPB A;  2J9L A;  4P1O A;  2RC3 A;  3KXR A;  3KPC A;  4COO A;  4IYS A;  4O9K A;  3HF7 A;  1O50 A;  2UV7 A;  2JA3 A;  3FWR A;  4GQW A;  5KS7 A;  2NYC A;  2QRD E;  5K22 B;  2EF7 A;  5IIP A;  3TDH C;  1Y5H A;  2OUX A;  2RIH A;  2YVY A;  3KPD A;  3L31 A;  2QR1 E;  3LHH A;  4ESY A;  4L28 A;  3PC3 A;  2UV5 A;  2OOX E;  1PBJ A;  3KH5 A;  4L3V A;  5K24 C;  5K25 C;  4FRY A;  3I8N A;  3DDJ A;  2YZI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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