2QR1E

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
332
structure length
324
Chain Sequence
DVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLADILNYIIYDKTTDNFESAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 96
structure length 324
sequence length 332
chains with identical sequence G
ec nomenclature
pdb deposition date 2007-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2qr1E02
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2qr1E01
3PC3A 5MMZA 2UV6A 3GBYA 4IY4A 3FHMA 4L27A 2QRCE 3T4NC 3LQNA 2YZQA 4IY3A 2O16A 3SL7A 4L0DA 2QREE 5K24C 2QRDE 3KPCA 4GQWA 2RC3A 1XKFA 3FWSA 3OI8A 4IYSA 1PVMA 2D4ZA 3KXRA 4IY0A 2RIHA 4HG0A 3TDHC 3FNAA 3FV6A 3LFZA 4ESYB 2OUXA 4UUUA 1YAVA 3PC4A 4NOCA 3ORGA 2NYEA 2ZY9A 3OCOA 5LXQA 3HF7A 4P1GA 5K22B 3I8NA 4DQWA 2OOXE 2UV7A 3DDJA 2RIFA 1O50A 3LHHA 5K25C 2P9MA 4P1OA 3LV9A 4L3VA 3TE5C 5K23C 2PFIA 3KPBA 3L31A 2UV4A 5IIPA 3PC2A 3FWRA 4COOA 2NYCA 2YZIA 1PBJA 4GQYA 1Y5HA 3L2BA 2QH1A 2EF7A 3K6EA 2OOYE 2EMQA 4L28A 2QR1E 3OCMA 3KH5A 4ESYA 4FRYA 4FXSA 4GQVA 3KPDA 4O9KA 2QLVC 4IY2A 2YVYA 2YVXA 2UV5A 2YVZA 3K2VA 4PCUA 5KS7A
chains in the Genus database with same CATH superfamily
3PC3A 5MMZA 2UV6A 3GBYA 4IY4A 3FHMA 4L27A 2J9LA 2QRCE 3T4NC 3LQNA 2YZQA 4IY3A 2O16A 3SL7A 4L0DA 2QREE 5K24C 2QRDE 3KPCA 4GQWA 2RC3A 1XKFA 3FWSA 3OI8A 4IYSA 2JA3A 1PVMA 2D4ZA 3KXRA 4IY0A 2RIHA 4HG0A 3TDHC 3FNAA 3FV6A 3LFZA 4ESYB 2OUXA 4UUUA 1YAVA 3PC4A 4NOCA 3ORGA 2NYEA 2ZY9A 3OCOA 5LXQA 3HF7A 4P1GA 5K22B 3I8NA 4DQWA 2OOXE 2UV7A 3DDJA 2RIFA 1O50A 3LHHA 5K25C 2P9MA 4P1OA 3LV9A 4L3VA 3TE5C 5K23C 2PFIA 3KPBA 3L31A 2UV4A 5IIPA 3PC2A 3FWRA 4COOA 2NYCA 2YZIA 1PBJA 4GQYA 1Y5HA 3L2BA 2EF7A 2QH1A 3K6EA 2OOYE 2EMQA 4L28A 2QR1E 3OCMA 3KH5A 4ESYA 4FRYA 4FXSA 4GQVA 3KPDA 4O9KA 2QLVC 4IY2A 2YVYA 2YVXA 2UV5A 2YVZA 3K2VA 4PCUA 5KS7A
chains in the Genus database with same CATH topology
3PC3A 5MMZA 2UV6A 3GBYA 4IY4A 3FHMA 4L27A 2J9LA 2QRCE 3T4NC 3LQNA 2YZQA 4IY3A 2O16A 3SL7A 4L0DA 2QREE 5K24C 2QRDE 3KPCA 4GQWA 2RC3A 1XKFA 3FWSA 3OI8A 4IYSA 2JA3A 1PVMA 2D4ZA 3KXRA 4IY0A 2RIHA 4HG0A 3TDHC 3FNAA 3FV6A 3LFZA 4ESYB 2OUXA 4UUUA 1YAVA 3PC4A 4NOCA 3ORGA 2NYEA 2ZY9A 3OCOA 5LXQA 3HF7A 4P1GA 5K22B 3I8NA 4DQWA 2OOXE 2UV7A 3DDJA 2RIFA 1O50A 3LHHA 5K25C 2P9MA 4P1OA 3LV9A 4L3VA 3TE5C 5K23C 2PFIA 3KPBA 3L31A 2UV4A 5IIPA 3PC2A 3FWRA 4COOA 2NYCA 2YZIA 1PBJA 4GQYA 1Y5HA 3L2BA 2EF7A 2QH1A 3K6EA 2OOYE 2EMQA 4L28A 2QR1E 3OCMA 3KH5A 4ESYA 4FRYA 4FXSA 4GQVA 3KPDA 4O9KA 2QLVC 4IY2A 2YVYA 2YVXA 2UV5A 2YVZA 3K2VA 4PCUA 5KS7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PC3 A;  5MMZ A;  2UV6 A;  3GBY A;  4IY4 A;  3FHM A;  4L27 A;  2QRC E;  3T4N C;  3LQN A;  2YZQ A;  4IY3 A;  2O16 A;  3SL7 A;  4L0D A;  2QRE E;  5K24 C;  2QRD E;  3KPC A;  4GQW A;  2RC3 A;  1XKF A;  3FWS A;  3OI8 A;  4IYS A;  1PVM A;  2D4Z A;  3KXR A;  4IY0 A;  2RIH A;  4HG0 A;  3TDH C;  3FNA A;  3FV6 A;  3LFZ A;  4ESY B;  2OUX A;  4UUU A;  1YAV A;  3PC4 A;  4NOC A;  3ORG A;  2NYE A;  2ZY9 A;  3OCO A;  5LXQ A;  3HF7 A;  4P1G A;  5K22 B;  3I8N A;  4DQW A;  2OOX E;  2UV7 A;  3DDJ A;  2RIF A;  1O50 A;  3LHH A;  5K25 C;  2P9M A;  4P1O A;  3LV9 A;  4L3V A;  3TE5 C;  5K23 C;  2PFI A;  3KPB A;  3L31 A;  2UV4 A;  5IIP A;  3PC2 A;  3FWR A;  4COO A;  2NYC A;  2YZI A;  1PBJ A;  4GQY A;  1Y5H A;  3L2B A;  2QH1 A;  2EF7 A;  3K6E A;  2OOY E;  2EMQ A;  4L28 A;  2QR1 E;  3OCM A;  3KH5 A;  4ESY A;  4FRY A;  4FXS A;  4GQV A;  3KPD A;  4O9K A;  2QLV C;  4IY2 A;  2YVY A;  2YVX A;  2UV5 A;  2YVZ A;  3K2V A;  4PCU A;  5KS7 A; 
#chains in the Genus database with same CATH topology
 3PC3 A;  5MMZ A;  2UV6 A;  3GBY A;  4IY4 A;  3FHM A;  4L27 A;  2J9L A;  2QRC E;  3T4N C;  3LQN A;  2YZQ A;  4IY3 A;  2O16 A;  3SL7 A;  4L0D A;  2QRE E;  5K24 C;  2QRD E;  3KPC A;  4GQW A;  2RC3 A;  1XKF A;  3FWS A;  3OI8 A;  4IYS A;  2JA3 A;  1PVM A;  2D4Z A;  3KXR A;  4IY0 A;  2RIH A;  4HG0 A;  3TDH C;  3FNA A;  3FV6 A;  3LFZ A;  4ESY B;  2OUX A;  4UUU A;  1YAV A;  3PC4 A;  4NOC A;  3ORG A;  2NYE A;  2ZY9 A;  3OCO A;  5LXQ A;  3HF7 A;  4P1G A;  5K22 B;  3I8N A;  4DQW A;  2OOX E;  2UV7 A;  3DDJ A;  2RIF A;  1O50 A;  3LHH A;  5K25 C;  2P9M A;  4P1O A;  3LV9 A;  4L3V A;  3TE5 C;  5K23 C;  2PFI A;  3KPB A;  3L31 A;  2UV4 A;  5IIP A;  3PC2 A;  3FWR A;  4COO A;  2NYC A;  2YZI A;  1PBJ A;  4GQY A;  1Y5H A;  3L2B A;  2EF7 A;  2QH1 A;  3K6E A;  2OOY E;  2EMQ A;  4L28 A;  2QR1 E;  3OCM A;  3KH5 A;  4ESY A;  4FRY A;  4FXS A;  4GQV A;  3KPD A;  4O9K A;  2QLV C;  4IY2 A;  2YVY A;  2YVX A;  2UV5 A;  2YVZ A;  3K2V A;  4PCU A;  5KS7 A; 
#chains in the Genus database with same CATH homology
 3PC3 A;  5MMZ A;  2UV6 A;  3GBY A;  4IY4 A;  3FHM A;  4L27 A;  2J9L A;  2QRC E;  3T4N C;  3LQN A;  2YZQ A;  4IY3 A;  2O16 A;  3SL7 A;  4L0D A;  2QRE E;  5K24 C;  2QRD E;  3KPC A;  4GQW A;  2RC3 A;  1XKF A;  3FWS A;  3OI8 A;  4IYS A;  2JA3 A;  1PVM A;  2D4Z A;  3KXR A;  4IY0 A;  2RIH A;  4HG0 A;  3TDH C;  3FNA A;  3FV6 A;  3LFZ A;  4ESY B;  2OUX A;  4UUU A;  1YAV A;  3PC4 A;  4NOC A;  3ORG A;  2NYE A;  2ZY9 A;  3OCO A;  5LXQ A;  3HF7 A;  4P1G A;  5K22 B;  3I8N A;  4DQW A;  2OOX E;  2UV7 A;  3DDJ A;  2RIF A;  1O50 A;  3LHH A;  5K25 C;  2P9M A;  4P1O A;  3LV9 A;  4L3V A;  3TE5 C;  5K23 C;  2PFI A;  3KPB A;  3L31 A;  2UV4 A;  5IIP A;  3PC2 A;  3FWR A;  4COO A;  2NYC A;  2YZI A;  1PBJ A;  4GQY A;  1Y5H A;  3L2B A;  2EF7 A;  2QH1 A;  3K6E A;  2OOY E;  2EMQ A;  4L28 A;  2QR1 E;  3OCM A;  3KH5 A;  4ESY A;  4FRY A;  4FXS A;  4GQV A;  3KPD A;  4O9K A;  2QLV C;  4IY2 A;  2YVY A;  2YVX A;  2UV5 A;  2YVZ A;  3K2V A;  4PCU A;  5KS7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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