2QRCE

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with adp and amp
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
332
structure length
324
Chain Sequence
DVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLADILNYIIYDKTTDNFESAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 96
structure length 324
sequence length 332
chains with identical sequence G
ec nomenclature
pdb deposition date 2007-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2qrcE02
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2qrcE01
2NYEA 3GBYA 3FV6A 3KPCA 5K23C 4P1GA 1XKFA 5LXQA 2D4ZA 4FXSA 3TE5C 2OOXE 3KPBA 5KS7A 2QRCE 3TDHC 1YAVA 2YZQA 4PCUA 2RC3A 5K24C 3SL7A 5IIPA 3FWSA 3L2BA 4GQYA 4COOA 3K6EA 2O16A 2PFIA 5K25C 2OOYE 3KPDA 1Y5HA 4IY3A 1PBJA 4FRYA 2QH1A 2UV5A 2QLVC 4L27A 4NOCA 3KXRA 1O50A 2YVZA 5K22B 3I8NA 2NYCA 4HG0A 4IYSA 3LV9A 2UV7A 3ORGA 3FHMA 4P1OA 3DDJA 4IY4A 2ZY9A 3FNAA 3HF7A 4IY0A 4GQWA 3PC2A 3OCMA 2UV4A 4ESYB 2YVXA 2YZIA 2YVYA 4UUUA 2EMQA 2QRDE 5MMZA 4L3VA 2EF7A 4O9KA 3KH5A 3PC3A 2QREE 3LQNA 2RIHA 4DQWA 4GQVA 2UV6A 3K2VA 4ESYA 2P9MA 1PVMA 2OUXA 4L28A 3FWRA 2QR1E 3LFZA 3OI8A 2RIFA 4L0DA 3LHHA 3L31A 4IY2A 3PC4A 3T4NC 3OCOA
chains in the Genus database with same CATH superfamily
2NYEA 3GBYA 3FV6A 3KPCA 5K23C 4P1GA 1XKFA 5LXQA 2D4ZA 4FXSA 3TE5C 2OOXE 3KPBA 5KS7A 2QRCE 3TDHC 1YAVA 2YZQA 4PCUA 2RC3A 5K24C 3SL7A 5IIPA 3FWSA 3L2BA 4GQYA 4COOA 3K6EA 2O16A 2PFIA 5K25C 2OOYE 3KPDA 1Y5HA 4IY3A 1PBJA 4FRYA 2QH1A 2UV5A 2QLVC 4L27A 4NOCA 3KXRA 1O50A 2YVZA 5K22B 3I8NA 2NYCA 4HG0A 4IYSA 3LV9A 2UV7A 3ORGA 3FHMA 4P1OA 3DDJA 4IY4A 2J9LA 2ZY9A 3FNAA 3HF7A 4IY0A 4GQWA 3PC2A 3OCMA 2UV4A 4ESYB 2YVXA 2YZIA 2YVYA 4UUUA 2EMQA 2QRDE 5MMZA 4L3VA 2EF7A 4O9KA 3KH5A 3PC3A 2JA3A 2QREE 3LQNA 2RIHA 4DQWA 4GQVA 2UV6A 3K2VA 4ESYA 2P9MA 1PVMA 2OUXA 4L28A 3FWRA 2QR1E 3LFZA 3OI8A 2RIFA 4L0DA 3LHHA 3L31A 4IY2A 3PC4A 3T4NC 3OCOA
chains in the Genus database with same CATH topology
2NYEA 3GBYA 3FV6A 3KPCA 5K23C 4P1GA 1XKFA 5LXQA 2D4ZA 4FXSA 3TE5C 2OOXE 3KPBA 5KS7A 2QRCE 3TDHC 1YAVA 2YZQA 4PCUA 2RC3A 5K24C 3SL7A 5IIPA 3FWSA 3L2BA 4GQYA 4COOA 3K6EA 2O16A 2PFIA 5K25C 2OOYE 3KPDA 1Y5HA 4IY3A 1PBJA 4FRYA 2QH1A 2UV5A 2QLVC 4L27A 4NOCA 3KXRA 1O50A 2YVZA 5K22B 3I8NA 2NYCA 4HG0A 4IYSA 3LV9A 2UV7A 3ORGA 3FHMA 4P1OA 3DDJA 4IY4A 2J9LA 2ZY9A 3FNAA 3HF7A 4IY0A 4GQWA 3PC2A 3OCMA 2UV4A 4ESYB 2YVXA 2YZIA 2YVYA 4UUUA 2EMQA 2QRDE 5MMZA 4L3VA 2EF7A 4O9KA 3KH5A 3PC3A 2JA3A 2QREE 3LQNA 2RIHA 4DQWA 4GQVA 2UV6A 3K2VA 4ESYA 2P9MA 1PVMA 2OUXA 4L28A 3FWRA 2QR1E 3LFZA 3OI8A 2RIFA 4L0DA 3LHHA 3L31A 4IY2A 3PC4A 3T4NC 3OCOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NYE A;  3GBY A;  3FV6 A;  3KPC A;  5K23 C;  4P1G A;  1XKF A;  5LXQ A;  2D4Z A;  4FXS A;  3TE5 C;  2OOX E;  3KPB A;  5KS7 A;  2QRC E;  3TDH C;  1YAV A;  2YZQ A;  4PCU A;  2RC3 A;  5K24 C;  3SL7 A;  5IIP A;  3FWS A;  3L2B A;  4GQY A;  4COO A;  3K6E A;  2O16 A;  2PFI A;  5K25 C;  2OOY E;  3KPD A;  1Y5H A;  4IY3 A;  1PBJ A;  4FRY A;  2QH1 A;  2UV5 A;  2QLV C;  4L27 A;  4NOC A;  3KXR A;  1O50 A;  2YVZ A;  5K22 B;  3I8N A;  2NYC A;  4HG0 A;  4IYS A;  3LV9 A;  2UV7 A;  3ORG A;  3FHM A;  4P1O A;  3DDJ A;  4IY4 A;  2ZY9 A;  3FNA A;  3HF7 A;  4IY0 A;  4GQW A;  3PC2 A;  3OCM A;  2UV4 A;  4ESY B;  2YVX A;  2YZI A;  2YVY A;  4UUU A;  2EMQ A;  2QRD E;  5MMZ A;  4L3V A;  2EF7 A;  4O9K A;  3KH5 A;  3PC3 A;  2QRE E;  3LQN A;  2RIH A;  4DQW A;  4GQV A;  2UV6 A;  3K2V A;  4ESY A;  2P9M A;  1PVM A;  2OUX A;  4L28 A;  3FWR A;  2QR1 E;  3LFZ A;  3OI8 A;  2RIF A;  4L0D A;  3LHH A;  3L31 A;  4IY2 A;  3PC4 A;  3T4N C;  3OCO A; 
#chains in the Genus database with same CATH topology
 2NYE A;  3GBY A;  3FV6 A;  3KPC A;  5K23 C;  4P1G A;  1XKF A;  5LXQ A;  2D4Z A;  4FXS A;  3TE5 C;  2OOX E;  3KPB A;  5KS7 A;  2QRC E;  3TDH C;  1YAV A;  2YZQ A;  4PCU A;  2RC3 A;  5K24 C;  3SL7 A;  5IIP A;  3FWS A;  3L2B A;  4GQY A;  4COO A;  3K6E A;  2O16 A;  2PFI A;  5K25 C;  2OOY E;  3KPD A;  1Y5H A;  4IY3 A;  1PBJ A;  4FRY A;  2QH1 A;  2UV5 A;  2QLV C;  4L27 A;  4NOC A;  3KXR A;  1O50 A;  2YVZ A;  5K22 B;  3I8N A;  2NYC A;  4HG0 A;  4IYS A;  3LV9 A;  2UV7 A;  3ORG A;  3FHM A;  4P1O A;  3DDJ A;  4IY4 A;  2J9L A;  2ZY9 A;  3FNA A;  3HF7 A;  4IY0 A;  4GQW A;  3PC2 A;  3OCM A;  2UV4 A;  4ESY B;  2YVX A;  2YZI A;  2YVY A;  4UUU A;  2EMQ A;  2QRD E;  5MMZ A;  4L3V A;  2EF7 A;  4O9K A;  3KH5 A;  3PC3 A;  2JA3 A;  2QRE E;  3LQN A;  2RIH A;  4DQW A;  4GQV A;  2UV6 A;  3K2V A;  4ESY A;  2P9M A;  1PVM A;  2OUX A;  4L28 A;  3FWR A;  2QR1 E;  3LFZ A;  3OI8 A;  2RIF A;  4L0D A;  3LHH A;  3L31 A;  4IY2 A;  3PC4 A;  3T4N C;  3OCO A; 
#chains in the Genus database with same CATH homology
 2NYE A;  3GBY A;  3FV6 A;  3KPC A;  5K23 C;  4P1G A;  1XKF A;  5LXQ A;  2D4Z A;  4FXS A;  3TE5 C;  2OOX E;  3KPB A;  5KS7 A;  2QRC E;  3TDH C;  1YAV A;  2YZQ A;  4PCU A;  2RC3 A;  5K24 C;  3SL7 A;  5IIP A;  3FWS A;  3L2B A;  4GQY A;  4COO A;  3K6E A;  2O16 A;  2PFI A;  5K25 C;  2OOY E;  3KPD A;  1Y5H A;  4IY3 A;  1PBJ A;  4FRY A;  2QH1 A;  2UV5 A;  2QLV C;  4L27 A;  4NOC A;  3KXR A;  1O50 A;  2YVZ A;  5K22 B;  3I8N A;  2NYC A;  4HG0 A;  4IYS A;  3LV9 A;  2UV7 A;  3ORG A;  3FHM A;  4P1O A;  3DDJ A;  4IY4 A;  2J9L A;  2ZY9 A;  3FNA A;  3HF7 A;  4IY0 A;  4GQW A;  3PC2 A;  3OCM A;  2UV4 A;  4ESY B;  2YVX A;  2YZI A;  2YVY A;  4UUU A;  2EMQ A;  2QRD E;  5MMZ A;  4L3V A;  2EF7 A;  4O9K A;  3KH5 A;  3PC3 A;  2JA3 A;  2QRE E;  3LQN A;  2RIH A;  4DQW A;  4GQV A;  2UV6 A;  3K2V A;  4ESY A;  2P9M A;  1PVM A;  2OUX A;  4L28 A;  3FWR A;  2QR1 E;  3LFZ A;  3OI8 A;  2RIF A;  4L0D A;  3LHH A;  3L31 A;  4IY2 A;  3PC4 A;  3T4N C;  3OCO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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