2QREE

Crystal structure of the adenylate sensor from amp-activated protein kinase in complex with 5-aminoimidazole-4-carboxamide 1-beta-d-ribofuranotide (zmp)
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
315
structure length
315
Chain Sequence
MDVQETQKGALKEIQAFIRSRTSYDVLPTSFRLIVFDVTLFVKTSLSLLTLNNIVSAPLWDSEANKFAGLLTMADFVNVIKYYYQSSSFPEAIAEIDKFRLLGLREVERKIGAIPPETIYVHPMHSLMDACLAMSKSRARRIPLIDVDGETGSEMIVSVLTQYRILKFISMNCKETAMLRVPLNQMTIGTWSNLATASMETKVYDVIKMLAEKNISAVPIVNSEGTLLNVYESVDVMHLIQDGDYSNLDLSVGEALLKRPANFDGVHTCRATDRLDGIFDAIKHSRVHRLFVVDENLKLEGILSLADILNYIIYD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insight into AMPK Regulation: ADP Comes into Play.
pubmed doi rcsb
molecule tags Transferase
source organism Schizosaccharomyces pombe
molecule keywords SNF1-like protein kinase ssp2
total genus 81
structure length 315
sequence length 315
chains with identical sequence G
ec nomenclature
pdb deposition date 2007-07-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2qreE02
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2qreE01
3L2BA 5IIPA 3PC2A 3ORGA 1Y5HA 3FV6A 3TE5C 1O50A 3FWSA 1XKFA 2RC3A 3LHHA 3I8NA 2QRCE 4P1GA 4O9KA 4IY2A 2UV4A 3KPCA 4GQWA 2YVXA 2UV5A 3TDHC 1PVMA 3OCMA 3L31A 4FRYA 4GQVA 3LQNA 3OCOA 2P9MA 4NOCA 3KH5A 4ESYA 3DDJA 4PCUA 2QREE 2RIHA 2YZQA 4ESYB 3KPBA 3FHMA 3PC4A 2UV7A 2PFIA 3LFZA 2QRDE 2QLVC 2EF7A 2NYEA 3OI8A 4FXSA 2UV6A 2QR1E 2O16A 4L3VA 2ZY9A 4DQWA 3SL7A 5MMZA 1YAVA 3K2VA 3LV9A 3HF7A 2YVYA 4COOA 2OOXE 5LXQA 4L27A 2OUXA 4L28A 3FWRA 4IY3A 3PC3A 2NYCA 5KS7A 4IY0A 2D4ZA 4P1OA 4GQYA 4UUUA 3GBYA 2QH1A 4IY4A 4L0DA 1PBJA 2RIFA 3T4NC 5K24C 2OOYE 2EMQA 4HG0A 2YVZA 4IYSA 3K6EA 5K23C 5K22B 3KXRA 5K25C 3KPDA 3FNAA 2YZIA
chains in the Genus database with same CATH superfamily
3L2BA 5IIPA 3PC2A 3ORGA 1Y5HA 3FV6A 3TE5C 1O50A 3FWSA 1XKFA 2RC3A 3LHHA 3I8NA 2QRCE 4P1GA 2JA3A 4O9KA 4IY2A 2UV4A 3KPCA 4GQWA 2YVXA 2UV5A 3TDHC 1PVMA 3OCMA 3L31A 4FRYA 4GQVA 3LQNA 3OCOA 2P9MA 4NOCA 3KH5A 4ESYA 3DDJA 4PCUA 2QREE 2RIHA 2YZQA 4ESYB 3KPBA 3FHMA 3PC4A 2UV7A 2PFIA 3LFZA 2QRDE 2QLVC 2EF7A 2NYEA 3OI8A 4FXSA 2UV6A 2QR1E 2O16A 4L3VA 2ZY9A 4DQWA 3SL7A 2J9LA 5MMZA 1YAVA 3K2VA 3LV9A 3HF7A 2YVYA 4COOA 2OOXE 5LXQA 4L27A 2OUXA 4L28A 3FWRA 4IY3A 3PC3A 2NYCA 5KS7A 4IY0A 2D4ZA 4P1OA 4GQYA 4UUUA 3GBYA 2QH1A 4IY4A 4L0DA 1PBJA 2RIFA 3T4NC 5K24C 2OOYE 2EMQA 4HG0A 2YVZA 4IYSA 3K6EA 5K23C 5K22B 3KXRA 5K25C 3KPDA 3FNAA 2YZIA
chains in the Genus database with same CATH topology
3L2BA 5IIPA 3PC2A 3ORGA 1Y5HA 3FV6A 3TE5C 1O50A 3FWSA 1XKFA 2RC3A 3LHHA 3I8NA 2QRCE 4P1GA 2JA3A 4O9KA 4IY2A 2UV4A 3KPCA 4GQWA 2YVXA 2UV5A 3TDHC 1PVMA 3OCMA 3L31A 4FRYA 4GQVA 3LQNA 3OCOA 2P9MA 4NOCA 3KH5A 4ESYA 3DDJA 4PCUA 2QREE 2RIHA 2YZQA 4ESYB 3KPBA 3FHMA 3PC4A 2UV7A 2PFIA 3LFZA 2QRDE 2QLVC 2EF7A 2NYEA 3OI8A 4FXSA 2UV6A 2QR1E 2O16A 4L3VA 2ZY9A 4DQWA 3SL7A 2J9LA 5MMZA 1YAVA 3K2VA 3LV9A 3HF7A 2YVYA 4COOA 2OOXE 5LXQA 4L27A 2OUXA 4L28A 3FWRA 4IY3A 3PC3A 2NYCA 5KS7A 4IY0A 2D4ZA 4P1OA 4GQYA 4UUUA 3GBYA 2QH1A 4IY4A 4L0DA 1PBJA 2RIFA 3T4NC 5K24C 2OOYE 2EMQA 4HG0A 2YVZA 4IYSA 3K6EA 5K23C 5K22B 3KXRA 5K25C 3KPDA 3FNAA 2YZIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L2B A;  5IIP A;  3PC2 A;  3ORG A;  1Y5H A;  3FV6 A;  3TE5 C;  1O50 A;  3FWS A;  1XKF A;  2RC3 A;  3LHH A;  3I8N A;  2QRC E;  4P1G A;  4O9K A;  4IY2 A;  2UV4 A;  3KPC A;  4GQW A;  2YVX A;  2UV5 A;  3TDH C;  1PVM A;  3OCM A;  3L31 A;  4FRY A;  4GQV A;  3LQN A;  3OCO A;  2P9M A;  4NOC A;  3KH5 A;  4ESY A;  3DDJ A;  4PCU A;  2QRE E;  2RIH A;  2YZQ A;  4ESY B;  3KPB A;  3FHM A;  3PC4 A;  2UV7 A;  2PFI A;  3LFZ A;  2QRD E;  2QLV C;  2EF7 A;  2NYE A;  3OI8 A;  4FXS A;  2UV6 A;  2QR1 E;  2O16 A;  4L3V A;  2ZY9 A;  4DQW A;  3SL7 A;  5MMZ A;  1YAV A;  3K2V A;  3LV9 A;  3HF7 A;  2YVY A;  4COO A;  2OOX E;  5LXQ A;  4L27 A;  2OUX A;  4L28 A;  3FWR A;  4IY3 A;  3PC3 A;  2NYC A;  5KS7 A;  4IY0 A;  2D4Z A;  4P1O A;  4GQY A;  4UUU A;  3GBY A;  2QH1 A;  4IY4 A;  4L0D A;  1PBJ A;  2RIF A;  3T4N C;  5K24 C;  2OOY E;  2EMQ A;  4HG0 A;  2YVZ A;  4IYS A;  3K6E A;  5K23 C;  5K22 B;  3KXR A;  5K25 C;  3KPD A;  3FNA A;  2YZI A; 
#chains in the Genus database with same CATH topology
 3L2B A;  5IIP A;  3PC2 A;  3ORG A;  1Y5H A;  3FV6 A;  3TE5 C;  1O50 A;  3FWS A;  1XKF A;  2RC3 A;  3LHH A;  3I8N A;  2QRC E;  4P1G A;  2JA3 A;  4O9K A;  4IY2 A;  2UV4 A;  3KPC A;  4GQW A;  2YVX A;  2UV5 A;  3TDH C;  1PVM A;  3OCM A;  3L31 A;  4FRY A;  4GQV A;  3LQN A;  3OCO A;  2P9M A;  4NOC A;  3KH5 A;  4ESY A;  3DDJ A;  4PCU A;  2QRE E;  2RIH A;  2YZQ A;  4ESY B;  3KPB A;  3FHM A;  3PC4 A;  2UV7 A;  2PFI A;  3LFZ A;  2QRD E;  2QLV C;  2EF7 A;  2NYE A;  3OI8 A;  4FXS A;  2UV6 A;  2QR1 E;  2O16 A;  4L3V A;  2ZY9 A;  4DQW A;  3SL7 A;  2J9L A;  5MMZ A;  1YAV A;  3K2V A;  3LV9 A;  3HF7 A;  2YVY A;  4COO A;  2OOX E;  5LXQ A;  4L27 A;  2OUX A;  4L28 A;  3FWR A;  4IY3 A;  3PC3 A;  2NYC A;  5KS7 A;  4IY0 A;  2D4Z A;  4P1O A;  4GQY A;  4UUU A;  3GBY A;  2QH1 A;  4IY4 A;  4L0D A;  1PBJ A;  2RIF A;  3T4N C;  5K24 C;  2OOY E;  2EMQ A;  4HG0 A;  2YVZ A;  4IYS A;  3K6E A;  5K23 C;  5K22 B;  3KXR A;  5K25 C;  3KPD A;  3FNA A;  2YZI A; 
#chains in the Genus database with same CATH homology
 3L2B A;  5IIP A;  3PC2 A;  3ORG A;  1Y5H A;  3FV6 A;  3TE5 C;  1O50 A;  3FWS A;  1XKF A;  2RC3 A;  3LHH A;  3I8N A;  2QRC E;  4P1G A;  2JA3 A;  4O9K A;  4IY2 A;  2UV4 A;  3KPC A;  4GQW A;  2YVX A;  2UV5 A;  3TDH C;  1PVM A;  3OCM A;  3L31 A;  4FRY A;  4GQV A;  3LQN A;  3OCO A;  2P9M A;  4NOC A;  3KH5 A;  4ESY A;  3DDJ A;  4PCU A;  2QRE E;  2RIH A;  2YZQ A;  4ESY B;  3KPB A;  3FHM A;  3PC4 A;  2UV7 A;  2PFI A;  3LFZ A;  2QRD E;  2QLV C;  2EF7 A;  2NYE A;  3OI8 A;  4FXS A;  2UV6 A;  2QR1 E;  2O16 A;  4L3V A;  2ZY9 A;  4DQW A;  3SL7 A;  2J9L A;  5MMZ A;  1YAV A;  3K2V A;  3LV9 A;  3HF7 A;  2YVY A;  4COO A;  2OOX E;  5LXQ A;  4L27 A;  2OUX A;  4L28 A;  3FWR A;  4IY3 A;  3PC3 A;  2NYC A;  5KS7 A;  4IY0 A;  2D4Z A;  4P1O A;  4GQY A;  4UUU A;  3GBY A;  2QH1 A;  4IY4 A;  4L0D A;  1PBJ A;  2RIF A;  3T4N C;  5K24 C;  2OOY E;  2EMQ A;  4HG0 A;  2YVZ A;  4IYS A;  3K6E A;  5K23 C;  5K22 B;  3KXR A;  5K25 C;  3KPD A;  3FNA A;  2YZI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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