2UV7A

Crystal structure of a cbs domain pair from the regulatory gamma1 subunit of human ampk in complex with amp
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
143
structure length
143
Chain Sequence
HEFPKPEFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHGLVVVDENDVVKGIVSLSDILQALV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of a Cbs-Domain Pair from the Regulatory Gamma1 Subunit of Human Ampk in Complex with AMP and Zmp.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT GAMMA-1
total genus 39
structure length 143
sequence length 143
ec nomenclature
pdb deposition date 2007-03-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 2uv7A00
2YZQA 2YVYA 2NYEA 2QRCE 4GQWA 3L31A 3LQNA 4L3VA 2QH1A 2UV4A 4O9KA 5K25C 3DDJA 3TDHC 2EF7A 3KPCA 5K24C 4L27A 4FRYA 1PBJA 3FNAA 5LXQA 4P1GA 2UV5A 4HG0A 1O50A 2RC3A 3OCMA 1YAVA 2D4ZA 3KXRA 4GQVA 5KS7A 2QR1E 3T4NC 4UUUA 3K6EA 5IIPA 2O16A 2RIFA 4IY3A 2YVZA 4IY2A 4IY0A 2OOXE 2QLVC 3GBYA 3KPDA 2PFIA 2OUXA 5K22B 4FXSA 3LV9A 2QREE 3HF7A 4IYSA 3L2BA 4COOA 3TE5C 3FWRA 4IY4A 1Y5HA 3OI8A 4L0DA 3SL7A 3FWSA 3KH5A 3LFZA 5MMZA 2NYCA 3ORGA 3FV6A 3LHHA 4P1OA 3FHMA 4GQYA 4DQWA 3PC3A 3OCOA 2YVXA 2QRDE 1PVMA 4ESYB 2UV7A 5K23C 3I8NA 2OOYE 4PCUA 2ZY9A 4NOCA 4L28A 2P9MA 1XKFA 2RIHA 4ESYA 3KPBA 3PC4A 3PC2A 3K2VA 2UV6A 2YZIA 2EMQA
chains in the Genus database with same CATH superfamily
2YZQA 2YVYA 2NYEA 2QRCE 4GQWA 3L31A 3LQNA 4L3VA 2QH1A 2UV4A 4O9KA 5K25C 3DDJA 3TDHC 2EF7A 3KPCA 5K24C 4L27A 4FRYA 1PBJA 3FNAA 5LXQA 4P1GA 2UV5A 4HG0A 1O50A 2RC3A 3OCMA 1YAVA 2D4ZA 3KXRA 4GQVA 5KS7A 2QR1E 3T4NC 4UUUA 3K6EA 5IIPA 2O16A 2RIFA 2J9LA 4IY3A 2YVZA 4IY2A 2OOXE 4IY0A 2QLVC 3GBYA 3KPDA 2PFIA 2OUXA 5K22B 4FXSA 3LV9A 2QREE 3HF7A 4IYSA 3L2BA 4COOA 3TE5C 3FWRA 4IY4A 1Y5HA 3OI8A 4L0DA 3SL7A 3FWSA 3KH5A 3LFZA 5MMZA 2NYCA 3ORGA 3FV6A 3LHHA 4P1OA 3FHMA 4GQYA 4DQWA 3PC3A 3OCOA 2YVXA 2QRDE 1PVMA 4ESYB 2UV7A 5K23C 3I8NA 2OOYE 4PCUA 2ZY9A 4NOCA 4L28A 2P9MA 2JA3A 1XKFA 2RIHA 4ESYA 3KPBA 3PC4A 3PC2A 3K2VA 2UV6A 2YZIA 2EMQA
chains in the Genus database with same CATH topology
2YZQA 2YVYA 2NYEA 2QRCE 4GQWA 3L31A 3LQNA 4L3VA 2QH1A 2UV4A 4O9KA 5K25C 3DDJA 3TDHC 2EF7A 3KPCA 5K24C 4L27A 4FRYA 1PBJA 3FNAA 5LXQA 4P1GA 2UV5A 4HG0A 1O50A 2RC3A 3OCMA 1YAVA 2D4ZA 3KXRA 4GQVA 5KS7A 2QR1E 3T4NC 4UUUA 3K6EA 5IIPA 2O16A 2RIFA 2J9LA 4IY3A 2YVZA 4IY2A 2OOXE 4IY0A 2QLVC 3GBYA 3KPDA 2PFIA 2OUXA 5K22B 4FXSA 3LV9A 2QREE 3HF7A 4IYSA 3L2BA 4COOA 3TE5C 3FWRA 4IY4A 1Y5HA 3OI8A 4L0DA 3SL7A 3FWSA 3KH5A 3LFZA 5MMZA 2NYCA 3ORGA 3FV6A 3LHHA 4P1OA 3FHMA 4GQYA 4DQWA 3PC3A 3OCOA 2YVXA 2QRDE 1PVMA 4ESYB 2UV7A 5K23C 3I8NA 2OOYE 4PCUA 2ZY9A 4NOCA 4L28A 2P9MA 2JA3A 1XKFA 2RIHA 4ESYA 3KPBA 3PC4A 3PC2A 3K2VA 2UV6A 2YZIA 2EMQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YZQ A;  2YVY A;  2NYE A;  2QRC E;  4GQW A;  3L31 A;  3LQN A;  4L3V A;  2QH1 A;  2UV4 A;  4O9K A;  5K25 C;  3DDJ A;  3TDH C;  2EF7 A;  3KPC A;  5K24 C;  4L27 A;  4FRY A;  1PBJ A;  3FNA A;  5LXQ A;  4P1G A;  2UV5 A;  4HG0 A;  1O50 A;  2RC3 A;  3OCM A;  1YAV A;  2D4Z A;  3KXR A;  4GQV A;  5KS7 A;  2QR1 E;  3T4N C;  4UUU A;  3K6E A;  5IIP A;  2O16 A;  2RIF A;  4IY3 A;  2YVZ A;  4IY2 A;  4IY0 A;  2OOX E;  2QLV C;  3GBY A;  3KPD A;  2PFI A;  2OUX A;  5K22 B;  4FXS A;  3LV9 A;  2QRE E;  3HF7 A;  4IYS A;  3L2B A;  4COO A;  3TE5 C;  3FWR A;  4IY4 A;  1Y5H A;  3OI8 A;  4L0D A;  3SL7 A;  3FWS A;  3KH5 A;  3LFZ A;  5MMZ A;  2NYC A;  3ORG A;  3FV6 A;  3LHH A;  4P1O A;  3FHM A;  4GQY A;  4DQW A;  3PC3 A;  3OCO A;  2YVX A;  2QRD E;  1PVM A;  4ESY B;  2UV7 A;  5K23 C;  3I8N A;  2OOY E;  4PCU A;  2ZY9 A;  4NOC A;  4L28 A;  2P9M A;  1XKF A;  2RIH A;  4ESY A;  3KPB A;  3PC4 A;  3PC2 A;  3K2V A;  2UV6 A;  2YZI A;  2EMQ A; 
#chains in the Genus database with same CATH topology
 2YZQ A;  2YVY A;  2NYE A;  2QRC E;  4GQW A;  3L31 A;  3LQN A;  4L3V A;  2QH1 A;  2UV4 A;  4O9K A;  5K25 C;  3DDJ A;  3TDH C;  2EF7 A;  3KPC A;  5K24 C;  4L27 A;  4FRY A;  1PBJ A;  3FNA A;  5LXQ A;  4P1G A;  2UV5 A;  4HG0 A;  1O50 A;  2RC3 A;  3OCM A;  1YAV A;  2D4Z A;  3KXR A;  4GQV A;  5KS7 A;  2QR1 E;  3T4N C;  4UUU A;  3K6E A;  5IIP A;  2O16 A;  2RIF A;  2J9L A;  4IY3 A;  2YVZ A;  4IY2 A;  2OOX E;  4IY0 A;  2QLV C;  3GBY A;  3KPD A;  2PFI A;  2OUX A;  5K22 B;  4FXS A;  3LV9 A;  2QRE E;  3HF7 A;  4IYS A;  3L2B A;  4COO A;  3TE5 C;  3FWR A;  4IY4 A;  1Y5H A;  3OI8 A;  4L0D A;  3SL7 A;  3FWS A;  3KH5 A;  3LFZ A;  5MMZ A;  2NYC A;  3ORG A;  3FV6 A;  3LHH A;  4P1O A;  3FHM A;  4GQY A;  4DQW A;  3PC3 A;  3OCO A;  2YVX A;  2QRD E;  1PVM A;  4ESY B;  2UV7 A;  5K23 C;  3I8N A;  2OOY E;  4PCU A;  2ZY9 A;  4NOC A;  4L28 A;  2P9M A;  2JA3 A;  1XKF A;  2RIH A;  4ESY A;  3KPB A;  3PC4 A;  3PC2 A;  3K2V A;  2UV6 A;  2YZI A;  2EMQ A; 
#chains in the Genus database with same CATH homology
 2YZQ A;  2YVY A;  2NYE A;  2QRC E;  4GQW A;  3L31 A;  3LQN A;  4L3V A;  2QH1 A;  2UV4 A;  4O9K A;  5K25 C;  3DDJ A;  3TDH C;  2EF7 A;  3KPC A;  5K24 C;  4L27 A;  4FRY A;  1PBJ A;  3FNA A;  5LXQ A;  4P1G A;  2UV5 A;  4HG0 A;  1O50 A;  2RC3 A;  3OCM A;  1YAV A;  2D4Z A;  3KXR A;  4GQV A;  5KS7 A;  2QR1 E;  3T4N C;  4UUU A;  3K6E A;  5IIP A;  2O16 A;  2RIF A;  2J9L A;  4IY3 A;  2YVZ A;  4IY2 A;  2OOX E;  4IY0 A;  2QLV C;  3GBY A;  3KPD A;  2PFI A;  2OUX A;  5K22 B;  4FXS A;  3LV9 A;  2QRE E;  3HF7 A;  4IYS A;  3L2B A;  4COO A;  3TE5 C;  3FWR A;  4IY4 A;  1Y5H A;  3OI8 A;  4L0D A;  3SL7 A;  3FWS A;  3KH5 A;  3LFZ A;  5MMZ A;  2NYC A;  3ORG A;  3FV6 A;  3LHH A;  4P1O A;  3FHM A;  4GQY A;  4DQW A;  3PC3 A;  3OCO A;  2YVX A;  2QRD E;  1PVM A;  4ESY B;  2UV7 A;  5K23 C;  3I8N A;  2OOY E;  4PCU A;  2ZY9 A;  4NOC A;  4L28 A;  2P9M A;  2JA3 A;  1XKF A;  2RIH A;  4ESY A;  3KPB A;  3PC4 A;  3PC2 A;  3K2V A;  2UV6 A;  2YZI A;  2EMQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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