3KPBA

Crystal structure of the cbs domain pair of protein mj0100 in complex with 5 -methylthioadenosine and s-adenosyl-l-methionine.
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
119
Chain Sequence
TLVKDILSKPPITAHSNISIMEAAKILIKHNINHLPIVDEHGKLVGIITSWDIAKALAQNKKTIEEIMTRNVITAHEDEPVDHVAIKMSKYNISGVPVVDDYRRVVGIVTSEDISRLFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Binding of S-Methyl-5'-Thioadenosine and S-Adenosyl-l-Methionine to Protein MJ0100 Triggers an Open-to-Closed Conformational Change in Its CBS Motif Pair.
pubmed doi rcsb
molecule tags Unknown function
source organism Methanocaldococcus jannaschii
molecule keywords Uncharacterized protein MJ0100
total genus 33
structure length 119
sequence length 119
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 3kpbA00
4GQYA 4PCUA 2YVZA 5LXQA 3ORGA 4DQWA 2OOYE 2P9MA 3OCMA 2UV7A 5IIPA 3L31A 2OOXE 2QR1E 2YZQA 2O16A 3KPDA 1O50A 2NYCA 5MMZA 3KH5A 1Y5HA 3TDHC 3KPCA 1XKFA 4IY3A 2RIFA 2QRCE 4ESYB 3KXRA 4ESYA 3PC3A 1PVMA 2EF7A 3K6EA 4COOA 4IY4A 4FRYA 3GBYA 3LHHA 2RIHA 2YVYA 4IYSA 3FV6A 4GQVA 2QRDE 3PC4A 5K23C 3FWRA 3LFZA 3LV9A 2QLVC 3DDJA 3OCOA 4O9KA 5K25C 2PFIA 4L0DA 3T4NC 3OI8A 3L2BA 4L28A 2RC3A 3FHMA 4L3VA 3K2VA 4IY0A 3PC2A 2UV5A 3TE5C 1PBJA 2EMQA 3I8NA 3FWSA 2UV6A 4IY2A 2QH1A 3HF7A 5KS7A 3SL7A 4GQWA 3LQNA 2OUXA 4P1GA 2UV4A 2YVXA 2NYEA 2ZY9A 2D4ZA 3FNAA 4NOCA 2QREE 5K22B 1YAVA 5K24C 2YZIA 4UUUA 3KPBA 4HG0A 4FXSA 4L27A 4P1OA
chains in the Genus database with same CATH superfamily
4GQYA 4PCUA 2YVZA 5LXQA 3ORGA 4DQWA 2OOYE 2P9MA 3OCMA 2UV7A 5IIPA 3L31A 2OOXE 2QR1E 2YZQA 2O16A 3KPDA 1O50A 2NYCA 5MMZA 3KH5A 1Y5HA 3TDHC 3KPCA 1XKFA 4IY3A 2RIFA 2QRCE 2J9LA 4ESYB 3KXRA 4ESYA 3PC3A 1PVMA 2EF7A 3K6EA 4COOA 4IY4A 4FRYA 3GBYA 3LHHA 2RIHA 2YVYA 4IYSA 3FV6A 4GQVA 2QRDE 3PC4A 5K23C 3FWRA 3LFZA 3LV9A 2QLVC 3DDJA 3OCOA 4O9KA 5K25C 2PFIA 4L0DA 3T4NC 3OI8A 3L2BA 4L28A 2RC3A 3FHMA 4L3VA 3K2VA 2JA3A 4IY0A 3PC2A 2UV5A 3TE5C 1PBJA 2EMQA 3I8NA 3FWSA 2UV6A 4IY2A 2QH1A 3HF7A 5KS7A 3SL7A 4GQWA 3LQNA 2OUXA 4P1GA 2UV4A 2YVXA 2NYEA 2ZY9A 2D4ZA 3FNAA 4NOCA 2QREE 5K22B 1YAVA 5K24C 2YZIA 4UUUA 3KPBA 4HG0A 4FXSA 4L27A 4P1OA
chains in the Genus database with same CATH topology
4GQYA 4PCUA 2YVZA 5LXQA 3ORGA 4DQWA 2OOYE 2P9MA 3OCMA 2UV7A 5IIPA 3L31A 2OOXE 2QR1E 2YZQA 2O16A 3KPDA 1O50A 2NYCA 5MMZA 3KH5A 1Y5HA 3TDHC 3KPCA 1XKFA 4IY3A 2RIFA 2QRCE 2J9LA 4ESYB 3KXRA 4ESYA 3PC3A 1PVMA 2EF7A 3K6EA 4COOA 4IY4A 4FRYA 3GBYA 3LHHA 2RIHA 2YVYA 4IYSA 3FV6A 4GQVA 2QRDE 3PC4A 5K23C 3FWRA 3LFZA 3LV9A 2QLVC 3DDJA 3OCOA 4O9KA 5K25C 2PFIA 4L0DA 3T4NC 3OI8A 3L2BA 4L28A 2RC3A 3FHMA 4L3VA 3K2VA 2JA3A 4IY0A 3PC2A 2UV5A 3TE5C 1PBJA 2EMQA 3I8NA 3FWSA 2UV6A 4IY2A 2QH1A 3HF7A 5KS7A 3SL7A 4GQWA 3LQNA 2OUXA 4P1GA 2UV4A 2YVXA 2NYEA 2ZY9A 2D4ZA 3FNAA 4NOCA 2QREE 5K22B 1YAVA 5K24C 2YZIA 4UUUA 3KPBA 4HG0A 4FXSA 4L27A 4P1OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GQY A;  4PCU A;  2YVZ A;  5LXQ A;  3ORG A;  4DQW A;  2OOY E;  2P9M A;  3OCM A;  2UV7 A;  5IIP A;  3L31 A;  2OOX E;  2QR1 E;  2YZQ A;  2O16 A;  3KPD A;  1O50 A;  2NYC A;  5MMZ A;  3KH5 A;  1Y5H A;  3TDH C;  3KPC A;  1XKF A;  4IY3 A;  2RIF A;  2QRC E;  4ESY B;  3KXR A;  4ESY A;  3PC3 A;  1PVM A;  2EF7 A;  3K6E A;  4COO A;  4IY4 A;  4FRY A;  3GBY A;  3LHH A;  2RIH A;  2YVY A;  4IYS A;  3FV6 A;  4GQV A;  2QRD E;  3PC4 A;  5K23 C;  3FWR A;  3LFZ A;  3LV9 A;  2QLV C;  3DDJ A;  3OCO A;  4O9K A;  5K25 C;  2PFI A;  4L0D A;  3T4N C;  3OI8 A;  3L2B A;  4L28 A;  2RC3 A;  3FHM A;  4L3V A;  3K2V A;  4IY0 A;  3PC2 A;  2UV5 A;  3TE5 C;  1PBJ A;  2EMQ A;  3I8N A;  3FWS A;  2UV6 A;  4IY2 A;  2QH1 A;  3HF7 A;  5KS7 A;  3SL7 A;  4GQW A;  3LQN A;  2OUX A;  4P1G A;  2UV4 A;  2YVX A;  2NYE A;  2ZY9 A;  2D4Z A;  3FNA A;  4NOC A;  2QRE E;  5K22 B;  1YAV A;  5K24 C;  2YZI A;  4UUU A;  3KPB A;  4HG0 A;  4FXS A;  4L27 A;  4P1O A; 
#chains in the Genus database with same CATH topology
 4GQY A;  4PCU A;  2YVZ A;  5LXQ A;  3ORG A;  4DQW A;  2OOY E;  2P9M A;  3OCM A;  2UV7 A;  5IIP A;  3L31 A;  2OOX E;  2QR1 E;  2YZQ A;  2O16 A;  3KPD A;  1O50 A;  2NYC A;  5MMZ A;  3KH5 A;  1Y5H A;  3TDH C;  3KPC A;  1XKF A;  4IY3 A;  2RIF A;  2QRC E;  2J9L A;  4ESY B;  3KXR A;  4ESY A;  3PC3 A;  1PVM A;  2EF7 A;  3K6E A;  4COO A;  4IY4 A;  4FRY A;  3GBY A;  3LHH A;  2RIH A;  2YVY A;  4IYS A;  3FV6 A;  4GQV A;  2QRD E;  3PC4 A;  5K23 C;  3FWR A;  3LFZ A;  3LV9 A;  2QLV C;  3DDJ A;  3OCO A;  4O9K A;  5K25 C;  2PFI A;  4L0D A;  3T4N C;  3OI8 A;  3L2B A;  4L28 A;  2RC3 A;  3FHM A;  4L3V A;  3K2V A;  2JA3 A;  4IY0 A;  3PC2 A;  2UV5 A;  3TE5 C;  1PBJ A;  2EMQ A;  3I8N A;  3FWS A;  2UV6 A;  4IY2 A;  2QH1 A;  3HF7 A;  5KS7 A;  3SL7 A;  4GQW A;  3LQN A;  2OUX A;  4P1G A;  2UV4 A;  2YVX A;  2NYE A;  2ZY9 A;  2D4Z A;  3FNA A;  4NOC A;  2QRE E;  5K22 B;  1YAV A;  5K24 C;  2YZI A;  4UUU A;  3KPB A;  4HG0 A;  4FXS A;  4L27 A;  4P1O A; 
#chains in the Genus database with same CATH homology
 4GQY A;  4PCU A;  2YVZ A;  5LXQ A;  3ORG A;  4DQW A;  2OOY E;  2P9M A;  3OCM A;  2UV7 A;  5IIP A;  3L31 A;  2OOX E;  2QR1 E;  2YZQ A;  2O16 A;  3KPD A;  1O50 A;  2NYC A;  5MMZ A;  3KH5 A;  1Y5H A;  3TDH C;  3KPC A;  1XKF A;  4IY3 A;  2RIF A;  2QRC E;  2J9L A;  4ESY B;  3KXR A;  4ESY A;  3PC3 A;  1PVM A;  2EF7 A;  3K6E A;  4COO A;  4IY4 A;  4FRY A;  3GBY A;  3LHH A;  2RIH A;  2YVY A;  4IYS A;  3FV6 A;  4GQV A;  2QRD E;  3PC4 A;  5K23 C;  3FWR A;  3LFZ A;  3LV9 A;  2QLV C;  3DDJ A;  3OCO A;  4O9K A;  5K25 C;  2PFI A;  4L0D A;  3T4N C;  3OI8 A;  3L2B A;  4L28 A;  2RC3 A;  3FHM A;  4L3V A;  3K2V A;  2JA3 A;  4IY0 A;  3PC2 A;  2UV5 A;  3TE5 C;  1PBJ A;  2EMQ A;  3I8N A;  3FWS A;  2UV6 A;  4IY2 A;  2QH1 A;  3HF7 A;  5KS7 A;  3SL7 A;  4GQW A;  3LQN A;  2OUX A;  4P1G A;  2UV4 A;  2YVX A;  2NYE A;  2ZY9 A;  2D4Z A;  3FNA A;  4NOC A;  2QRE E;  5K22 B;  1YAV A;  5K24 C;  2YZI A;  4UUU A;  3KPB A;  4HG0 A;  4FXS A;  4L27 A;  4P1O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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