3KPBA

Crystal structure of the cbs domain pair of protein mj0100 in complex with 5 -methylthioadenosine and s-adenosyl-l-methionine.
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
119
structure length
119
Chain Sequence
TLVKDILSKPPITAHSNISIMEAAKILIKHNINHLPIVDEHGKLVGIITSWDIAKALAQNKKTIEEIMTRNVITAHEDEPVDHVAIKMSKYNISGVPVVDDYRRVVGIVTSEDISRLFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Binding of S-Methyl-5'-Thioadenosine and S-Adenosyl-l-Methionine to Protein MJ0100 Triggers an Open-to-Closed Conformational Change in Its CBS Motif Pair.
pubmed doi rcsb
molecule tags Unknown function
source organism Methanocaldococcus jannaschii
molecule keywords Uncharacterized protein MJ0100
total genus 33
structure length 119
sequence length 119
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 3kpbA00
4P1GA 3KPDA 3L31A 5IIPA 3K6EA 3T4NC 2YVXA 3PC2A 2NYCA 3FWSA 3OI8A 3FWRA 4PCUA 3HF7A 4NOCA 3TE5C 2QR1E 5MMZA 1PVMA 3KXRA 2QH1A 2NYEA 5LXQA 3FNAA 2OOYE 1XKFA 4O9KA 2YZQA 4FXSA 3LQNA 4L3VA 1PBJA 3ORGA 4IY3A 2OOXE 2RC3A 3PC4A 2RIHA 3LHHA 4IY2A 4COOA 3OCMA 4ESYB 2OUXA 4IYSA 4GQYA 2UV6A 4UUUA 3FHMA 4IY0A 5K24C 4GQWA 2QRCE 3GBYA 1YAVA 3I8NA 3KPCA 2D4ZA 3FV6A 3LV9A 2RIFA 3TDHC 5K25C 2EF7A 2UV7A 2YVYA 2ZY9A 3KPBA 3LFZA 4DQWA 4IY4A 2EMQA 2YVZA 2QREE 5K22B 3KH5A 2QLVC 5KS7A 4FRYA 2YZIA 4GQVA 2UV4A 4L0DA 3SL7A 3L2BA 5K23C 2UV5A 4P1OA 2PFIA 3PC3A 4L27A 3K2VA 2QRDE 4ESYA 4HG0A 3OCOA 4L28A 1Y5HA 1O50A 2O16A 3DDJA 2P9MA
chains in the Genus database with same CATH superfamily
4P1GA 3KPDA 3L31A 5IIPA 3K6EA 3T4NC 2YVXA 3PC2A 2NYCA 3FWSA 3OI8A 3FWRA 4PCUA 3HF7A 4NOCA 3TE5C 2QR1E 5MMZA 1PVMA 3KXRA 2QH1A 2NYEA 5LXQA 3FNAA 2OOYE 1XKFA 4O9KA 2YZQA 4FXSA 3LQNA 4L3VA 1PBJA 2J9LA 3ORGA 4IY3A 2OOXE 2RC3A 3PC4A 2RIHA 3LHHA 4IY2A 4COOA 3OCMA 4ESYB 2OUXA 4IYSA 4GQYA 2UV6A 4UUUA 3FHMA 4IY0A 5K24C 4GQWA 2QRCE 3GBYA 1YAVA 3I8NA 3KPCA 2D4ZA 3FV6A 3LV9A 2RIFA 3TDHC 5K25C 2EF7A 2UV7A 2YVYA 2ZY9A 3KPBA 3LFZA 4DQWA 4IY4A 2EMQA 2YVZA 2QREE 5K22B 3KH5A 2QLVC 5KS7A 4FRYA 2YZIA 4GQVA 2UV4A 4L0DA 3SL7A 3L2BA 2JA3A 5K23C 2UV5A 4P1OA 2PFIA 3PC3A 4L27A 3K2VA 2QRDE 4ESYA 4HG0A 3OCOA 4L28A 1Y5HA 1O50A 2O16A 3DDJA 2P9MA
chains in the Genus database with same CATH topology
4P1GA 3KPDA 3L31A 5IIPA 3K6EA 3T4NC 2YVXA 3PC2A 2NYCA 3FWSA 3OI8A 3FWRA 4PCUA 3HF7A 4NOCA 3TE5C 2QR1E 5MMZA 1PVMA 3KXRA 2QH1A 2NYEA 5LXQA 3FNAA 2OOYE 1XKFA 4O9KA 2YZQA 4FXSA 3LQNA 4L3VA 1PBJA 2J9LA 3ORGA 4IY3A 2OOXE 2RC3A 3PC4A 2RIHA 3LHHA 4IY2A 4COOA 3OCMA 4ESYB 2OUXA 4IYSA 4GQYA 2UV6A 4UUUA 3FHMA 4IY0A 5K24C 4GQWA 2QRCE 3GBYA 1YAVA 3I8NA 3KPCA 2D4ZA 3FV6A 3LV9A 2RIFA 3TDHC 5K25C 2EF7A 2UV7A 2YVYA 2ZY9A 3KPBA 3LFZA 4DQWA 4IY4A 2EMQA 2YVZA 2QREE 5K22B 3KH5A 2QLVC 5KS7A 4FRYA 2YZIA 4GQVA 2UV4A 4L0DA 3SL7A 3L2BA 2JA3A 5K23C 2UV5A 4P1OA 2PFIA 3PC3A 4L27A 3K2VA 2QRDE 4ESYA 4HG0A 3OCOA 4L28A 1Y5HA 1O50A 2O16A 3DDJA 2P9MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1G A;  3KPD A;  3L31 A;  5IIP A;  3K6E A;  3T4N C;  2YVX A;  3PC2 A;  2NYC A;  3FWS A;  3OI8 A;  3FWR A;  4PCU A;  3HF7 A;  4NOC A;  3TE5 C;  2QR1 E;  5MMZ A;  1PVM A;  3KXR A;  2QH1 A;  2NYE A;  5LXQ A;  3FNA A;  2OOY E;  1XKF A;  4O9K A;  2YZQ A;  4FXS A;  3LQN A;  4L3V A;  1PBJ A;  3ORG A;  4IY3 A;  2OOX E;  2RC3 A;  3PC4 A;  2RIH A;  3LHH A;  4IY2 A;  4COO A;  3OCM A;  4ESY B;  2OUX A;  4IYS A;  4GQY A;  2UV6 A;  4UUU A;  3FHM A;  4IY0 A;  5K24 C;  4GQW A;  2QRC E;  3GBY A;  1YAV A;  3I8N A;  3KPC A;  2D4Z A;  3FV6 A;  3LV9 A;  2RIF A;  3TDH C;  5K25 C;  2EF7 A;  2UV7 A;  2YVY A;  2ZY9 A;  3KPB A;  3LFZ A;  4DQW A;  4IY4 A;  2EMQ A;  2YVZ A;  2QRE E;  5K22 B;  3KH5 A;  2QLV C;  5KS7 A;  4FRY A;  2YZI A;  4GQV A;  2UV4 A;  4L0D A;  3SL7 A;  3L2B A;  5K23 C;  2UV5 A;  4P1O A;  2PFI A;  3PC3 A;  4L27 A;  3K2V A;  2QRD E;  4ESY A;  4HG0 A;  3OCO A;  4L28 A;  1Y5H A;  1O50 A;  2O16 A;  3DDJ A;  2P9M A; 
#chains in the Genus database with same CATH topology
 4P1G A;  3KPD A;  3L31 A;  5IIP A;  3K6E A;  3T4N C;  2YVX A;  3PC2 A;  2NYC A;  3FWS A;  3OI8 A;  3FWR A;  4PCU A;  3HF7 A;  4NOC A;  3TE5 C;  2QR1 E;  5MMZ A;  1PVM A;  3KXR A;  2QH1 A;  2NYE A;  5LXQ A;  3FNA A;  2OOY E;  1XKF A;  4O9K A;  2YZQ A;  4FXS A;  3LQN A;  4L3V A;  1PBJ A;  2J9L A;  3ORG A;  4IY3 A;  2OOX E;  2RC3 A;  3PC4 A;  2RIH A;  3LHH A;  4IY2 A;  4COO A;  3OCM A;  4ESY B;  2OUX A;  4IYS A;  4GQY A;  2UV6 A;  4UUU A;  3FHM A;  4IY0 A;  5K24 C;  4GQW A;  2QRC E;  3GBY A;  1YAV A;  3I8N A;  3KPC A;  2D4Z A;  3FV6 A;  3LV9 A;  2RIF A;  3TDH C;  5K25 C;  2EF7 A;  2UV7 A;  2YVY A;  2ZY9 A;  3KPB A;  3LFZ A;  4DQW A;  4IY4 A;  2EMQ A;  2YVZ A;  2QRE E;  5K22 B;  3KH5 A;  2QLV C;  5KS7 A;  4FRY A;  2YZI A;  4GQV A;  2UV4 A;  4L0D A;  3SL7 A;  3L2B A;  2JA3 A;  5K23 C;  2UV5 A;  4P1O A;  2PFI A;  3PC3 A;  4L27 A;  3K2V A;  2QRD E;  4ESY A;  4HG0 A;  3OCO A;  4L28 A;  1Y5H A;  1O50 A;  2O16 A;  3DDJ A;  2P9M A; 
#chains in the Genus database with same CATH homology
 4P1G A;  3KPD A;  3L31 A;  5IIP A;  3K6E A;  3T4N C;  2YVX A;  3PC2 A;  2NYC A;  3FWS A;  3OI8 A;  3FWR A;  4PCU A;  3HF7 A;  4NOC A;  3TE5 C;  2QR1 E;  5MMZ A;  1PVM A;  3KXR A;  2QH1 A;  2NYE A;  5LXQ A;  3FNA A;  2OOY E;  1XKF A;  4O9K A;  2YZQ A;  4FXS A;  3LQN A;  4L3V A;  1PBJ A;  2J9L A;  3ORG A;  4IY3 A;  2OOX E;  2RC3 A;  3PC4 A;  2RIH A;  3LHH A;  4IY2 A;  4COO A;  3OCM A;  4ESY B;  2OUX A;  4IYS A;  4GQY A;  2UV6 A;  4UUU A;  3FHM A;  4IY0 A;  5K24 C;  4GQW A;  2QRC E;  3GBY A;  1YAV A;  3I8N A;  3KPC A;  2D4Z A;  3FV6 A;  3LV9 A;  2RIF A;  3TDH C;  5K25 C;  2EF7 A;  2UV7 A;  2YVY A;  2ZY9 A;  3KPB A;  3LFZ A;  4DQW A;  4IY4 A;  2EMQ A;  2YVZ A;  2QRE E;  5K22 B;  3KH5 A;  2QLV C;  5KS7 A;  4FRY A;  2YZI A;  4GQV A;  2UV4 A;  4L0D A;  3SL7 A;  3L2B A;  2JA3 A;  5K23 C;  2UV5 A;  4P1O A;  2PFI A;  3PC3 A;  4L27 A;  3K2V A;  2QRD E;  4ESY A;  4HG0 A;  3OCO A;  4L28 A;  1Y5H A;  1O50 A;  2O16 A;  3DDJ A;  2P9M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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