3KPDA

Crystal structure of the cbs domain pair of protein mj0100 in complex with 5 -methylthioadenosine and s-adenosyl-l-methionine.
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
119
structure length
119
Chain Sequence
TLVKDILSKPPITAHSNISIMEAAKILIKHNINHLPIVDEHGKLVGIITSWDIAKALAQNKKTIEEIMTRNVITAHEDEPVDHVAIKMSKYNISGVPVVDDYRRVVGIVTSEDISRLFG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Binding of S-Methyl-5'-Thioadenosine and S-Adenosyl-l-Methionine to Protein MJ0100 Triggers an Open-to-Closed Conformational Change in Its CBS Motif Pair.
pubmed doi rcsb
molecule tags Unknown function
source organism Methanocaldococcus jannaschii
molecule keywords Uncharacterized protein MJ0100
total genus 27
structure length 119
sequence length 119
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2009-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 3kpdA00
2PFIA 4L27A 4P1OA 2QREE 3KXRA 4NOCA 2YVYA 2ZY9A 3K6EA 4ESYB 4IY3A 2OUXA 3GBYA 4COOA 3I8NA 2YZQA 5K24C 3LFZA 1PVMA 3ORGA 2D4ZA 2P9MA 3TE5C 4GQVA 3OCMA 5K23C 5K22B 4GQYA 3FV6A 1PBJA 2RC3A 5LXQA 4HG0A 4O9KA 3KPBA 2NYCA 2QLVC 2EF7A 2QRDE 3PC3A 1Y5HA 2OOXE 2YVXA 4GQWA 5KS7A 3SL7A 2UV5A 1O50A 3OI8A 3FWRA 4PCUA 4L3VA 3FHMA 3FNAA 3PC4A 2NYEA 2UV6A 2UV7A 2YZIA 2RIFA 3LV9A 4FRYA 3K2VA 1XKFA 2QRCE 3DDJA 4FXSA 2O16A 2UV4A 3HF7A 3L31A 1YAVA 5K25C 4L0DA 4P1GA 2EMQA 2QR1E 3FWSA 3KPCA 2RIHA 3T4NC 2YVZA 3KH5A 4UUUA 4ESYA 4IY4A 4IY0A 3L2BA 2QH1A 3TDHC 3PC2A 3KPDA 3LQNA 5MMZA 3OCOA 5IIPA 4IYSA 4L28A 4DQWA 4IY2A 3LHHA 2OOYE
chains in the Genus database with same CATH superfamily
2PFIA 4L27A 4P1OA 2QREE 3KXRA 4NOCA 2YVYA 2ZY9A 3K6EA 4ESYB 4IY3A 2OUXA 3GBYA 4COOA 3I8NA 2J9LA 2YZQA 5K24C 3LFZA 1PVMA 3ORGA 2D4ZA 2P9MA 3TE5C 4GQVA 3OCMA 5K23C 5K22B 4GQYA 3FV6A 1PBJA 2RC3A 5LXQA 4HG0A 4O9KA 2JA3A 3KPBA 2NYCA 2EF7A 2QLVC 2QRDE 3PC3A 1Y5HA 2OOXE 2YVXA 4GQWA 5KS7A 3SL7A 2UV5A 1O50A 3OI8A 3FWRA 4PCUA 4L3VA 3FHMA 3FNAA 3PC4A 2NYEA 2UV6A 2UV7A 2YZIA 2RIFA 3LV9A 4FRYA 3K2VA 1XKFA 2QRCE 3DDJA 4FXSA 2O16A 2UV4A 3HF7A 3L31A 1YAVA 5K25C 4L0DA 4P1GA 2EMQA 2QR1E 3FWSA 3KPCA 2RIHA 3T4NC 2YVZA 3KH5A 4UUUA 4ESYA 4IY4A 4IY0A 3L2BA 2QH1A 3TDHC 3PC2A 3KPDA 3LQNA 5MMZA 3OCOA 5IIPA 4IYSA 4L28A 4DQWA 4IY2A 3LHHA 2OOYE
chains in the Genus database with same CATH topology
2PFIA 4L27A 4P1OA 2QREE 3KXRA 4NOCA 2YVYA 2ZY9A 3K6EA 4ESYB 4IY3A 2OUXA 3GBYA 4COOA 3I8NA 2J9LA 2YZQA 5K24C 3LFZA 1PVMA 3ORGA 2D4ZA 2P9MA 3TE5C 4GQVA 3OCMA 5K23C 5K22B 4GQYA 3FV6A 1PBJA 2RC3A 5LXQA 4HG0A 4O9KA 2JA3A 3KPBA 2NYCA 2EF7A 2QLVC 2QRDE 3PC3A 1Y5HA 2OOXE 2YVXA 4GQWA 5KS7A 3SL7A 2UV5A 1O50A 3OI8A 3FWRA 4PCUA 4L3VA 3FHMA 3FNAA 3PC4A 2NYEA 2UV6A 2UV7A 2YZIA 2RIFA 3LV9A 4FRYA 3K2VA 1XKFA 2QRCE 3DDJA 4FXSA 2O16A 2UV4A 3HF7A 3L31A 1YAVA 5K25C 4L0DA 4P1GA 2EMQA 2QR1E 3FWSA 3KPCA 2RIHA 3T4NC 2YVZA 3KH5A 4UUUA 4ESYA 4IY4A 4IY0A 3L2BA 2QH1A 3TDHC 3PC2A 3KPDA 3LQNA 5MMZA 3OCOA 5IIPA 4IYSA 4L28A 4DQWA 4IY2A 3LHHA 2OOYE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PFI A;  4L27 A;  4P1O A;  2QRE E;  3KXR A;  4NOC A;  2YVY A;  2ZY9 A;  3K6E A;  4ESY B;  4IY3 A;  2OUX A;  3GBY A;  4COO A;  3I8N A;  2YZQ A;  5K24 C;  3LFZ A;  1PVM A;  3ORG A;  2D4Z A;  2P9M A;  3TE5 C;  4GQV A;  3OCM A;  5K23 C;  5K22 B;  4GQY A;  3FV6 A;  1PBJ A;  2RC3 A;  5LXQ A;  4HG0 A;  4O9K A;  3KPB A;  2NYC A;  2QLV C;  2EF7 A;  2QRD E;  3PC3 A;  1Y5H A;  2OOX E;  2YVX A;  4GQW A;  5KS7 A;  3SL7 A;  2UV5 A;  1O50 A;  3OI8 A;  3FWR A;  4PCU A;  4L3V A;  3FHM A;  3FNA A;  3PC4 A;  2NYE A;  2UV6 A;  2UV7 A;  2YZI A;  2RIF A;  3LV9 A;  4FRY A;  3K2V A;  1XKF A;  2QRC E;  3DDJ A;  4FXS A;  2O16 A;  2UV4 A;  3HF7 A;  3L31 A;  1YAV A;  5K25 C;  4L0D A;  4P1G A;  2EMQ A;  2QR1 E;  3FWS A;  3KPC A;  2RIH A;  3T4N C;  2YVZ A;  3KH5 A;  4UUU A;  4ESY A;  4IY4 A;  4IY0 A;  3L2B A;  2QH1 A;  3TDH C;  3PC2 A;  3KPD A;  3LQN A;  5MMZ A;  3OCO A;  5IIP A;  4IYS A;  4L28 A;  4DQW A;  4IY2 A;  3LHH A;  2OOY E; 
#chains in the Genus database with same CATH topology
 2PFI A;  4L27 A;  4P1O A;  2QRE E;  3KXR A;  4NOC A;  2YVY A;  2ZY9 A;  3K6E A;  4ESY B;  4IY3 A;  2OUX A;  3GBY A;  4COO A;  3I8N A;  2J9L A;  2YZQ A;  5K24 C;  3LFZ A;  1PVM A;  3ORG A;  2D4Z A;  2P9M A;  3TE5 C;  4GQV A;  3OCM A;  5K23 C;  5K22 B;  4GQY A;  3FV6 A;  1PBJ A;  2RC3 A;  5LXQ A;  4HG0 A;  4O9K A;  2JA3 A;  3KPB A;  2NYC A;  2EF7 A;  2QLV C;  2QRD E;  3PC3 A;  1Y5H A;  2OOX E;  2YVX A;  4GQW A;  5KS7 A;  3SL7 A;  2UV5 A;  1O50 A;  3OI8 A;  3FWR A;  4PCU A;  4L3V A;  3FHM A;  3FNA A;  3PC4 A;  2NYE A;  2UV6 A;  2UV7 A;  2YZI A;  2RIF A;  3LV9 A;  4FRY A;  3K2V A;  1XKF A;  2QRC E;  3DDJ A;  4FXS A;  2O16 A;  2UV4 A;  3HF7 A;  3L31 A;  1YAV A;  5K25 C;  4L0D A;  4P1G A;  2EMQ A;  2QR1 E;  3FWS A;  3KPC A;  2RIH A;  3T4N C;  2YVZ A;  3KH5 A;  4UUU A;  4ESY A;  4IY4 A;  4IY0 A;  3L2B A;  2QH1 A;  3TDH C;  3PC2 A;  3KPD A;  3LQN A;  5MMZ A;  3OCO A;  5IIP A;  4IYS A;  4L28 A;  4DQW A;  4IY2 A;  3LHH A;  2OOY E; 
#chains in the Genus database with same CATH homology
 2PFI A;  4L27 A;  4P1O A;  2QRE E;  3KXR A;  4NOC A;  2YVY A;  2ZY9 A;  3K6E A;  4ESY B;  4IY3 A;  2OUX A;  3GBY A;  4COO A;  3I8N A;  2J9L A;  2YZQ A;  5K24 C;  3LFZ A;  1PVM A;  3ORG A;  2D4Z A;  2P9M A;  3TE5 C;  4GQV A;  3OCM A;  5K23 C;  5K22 B;  4GQY A;  3FV6 A;  1PBJ A;  2RC3 A;  5LXQ A;  4HG0 A;  4O9K A;  2JA3 A;  3KPB A;  2NYC A;  2EF7 A;  2QLV C;  2QRD E;  3PC3 A;  1Y5H A;  2OOX E;  2YVX A;  4GQW A;  5KS7 A;  3SL7 A;  2UV5 A;  1O50 A;  3OI8 A;  3FWR A;  4PCU A;  4L3V A;  3FHM A;  3FNA A;  3PC4 A;  2NYE A;  2UV6 A;  2UV7 A;  2YZI A;  2RIF A;  3LV9 A;  4FRY A;  3K2V A;  1XKF A;  2QRC E;  3DDJ A;  4FXS A;  2O16 A;  2UV4 A;  3HF7 A;  3L31 A;  1YAV A;  5K25 C;  4L0D A;  4P1G A;  2EMQ A;  2QR1 E;  3FWS A;  3KPC A;  2RIH A;  3T4N C;  2YVZ A;  3KH5 A;  4UUU A;  4ESY A;  4IY4 A;  4IY0 A;  3L2B A;  2QH1 A;  3TDH C;  3PC2 A;  3KPD A;  3LQN A;  5MMZ A;  3OCO A;  5IIP A;  4IYS A;  4L28 A;  4DQW A;  4IY2 A;  3LHH A;  2OOY E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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