4IY2A

Structural and ligand binding properties of the bateman domain of human magnesium transporters cnnm2 and cnnm4
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
152
structure length
152
Chain Sequence
MEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
rcsb
molecule tags Metal transport
source organism Homo sapiens
molecule keywords Metal transporter CNNM2
total genus 34
structure length 152
sequence length 152
chains with identical sequence C
ec nomenclature
pdb deposition date 2013-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 4iy2A00
2EF7A 4FXSA 2UV7A 3K2VA 2YZIA 4HG0A 4L27A 3K6EA 3TE5C 3I8NA 2QH1A 4IY2A 4COOA 1YAVA 2QREE 2ZY9A 2OUXA 3PC2A 5IIPA 4UUUA 2P9MA 1PBJA 2YVXA 3FWSA 3OCMA 4ESYB 3KPDA 3FHMA 2OOYE 1XKFA 3KPBA 5K22B 4IY0A 2YVZA 3GBYA 3LV9A 4L3VA 2QRDE 1O50A 1Y5HA 2RIHA 3FNAA 3HF7A 3T4NC 4P1GA 3TDHC 2D4ZA 2EMQA 3SL7A 3OCOA 4GQVA 4IYSA 2YZQA 2YVYA 2NYEA 4IY3A 3ORGA 3L2BA 5LXQA 5K23C 3FV6A 3LQNA 3FWRA 2RC3A 3OI8A 4P1OA 2PFIA 5MMZA 4DQWA 4FRYA 3L31A 4O9KA 2O16A 3KH5A 3PC4A 4NOCA 4IY4A 2UV4A 3LFZA 2QR1E 4L0DA 4GQYA 3DDJA 2QRCE 2OOXE 4L28A 4PCUA 3LHHA 3PC3A 4ESYA 5K24C 4GQWA 2UV5A 2NYCA 3KXRA 5K25C 2QLVC 5KS7A 2UV6A 1PVMA 2RIFA 3KPCA
chains in the Genus database with same CATH superfamily
2EF7A 4FXSA 2UV7A 3K2VA 2YZIA 4HG0A 4L27A 3K6EA 3TE5C 3I8NA 2QH1A 4IY2A 4COOA 1YAVA 2QREE 2ZY9A 2OUXA 2JA3A 3PC2A 5IIPA 4UUUA 2P9MA 1PBJA 2YVXA 2J9LA 3FWSA 3OCMA 4ESYB 3KPDA 3FHMA 2OOYE 1XKFA 3KPBA 5K22B 4IY0A 2YVZA 3GBYA 3LV9A 4L3VA 2QRDE 1O50A 1Y5HA 2RIHA 3FNAA 3HF7A 3T4NC 4P1GA 3TDHC 2D4ZA 2EMQA 3SL7A 3OCOA 4GQVA 4IYSA 2YZQA 2YVYA 2NYEA 4IY3A 3ORGA 3L2BA 5LXQA 5K23C 3FV6A 3LQNA 3FWRA 2RC3A 3OI8A 4P1OA 2PFIA 5MMZA 4DQWA 4FRYA 3L31A 4O9KA 2O16A 3KH5A 3PC4A 4NOCA 4IY4A 2UV4A 3LFZA 2QR1E 4L0DA 4GQYA 3DDJA 2QRCE 2OOXE 4L28A 4PCUA 3LHHA 3PC3A 4ESYA 5K24C 4GQWA 2UV5A 2NYCA 3KXRA 5K25C 2QLVC 5KS7A 2UV6A 1PVMA 2RIFA 3KPCA
chains in the Genus database with same CATH topology
2EF7A 4FXSA 2UV7A 3K2VA 2YZIA 4HG0A 4L27A 3K6EA 3TE5C 3I8NA 2QH1A 4IY2A 4COOA 1YAVA 2QREE 2ZY9A 2OUXA 2JA3A 3PC2A 5IIPA 4UUUA 2P9MA 1PBJA 2YVXA 2J9LA 3FWSA 3OCMA 4ESYB 3KPDA 3FHMA 2OOYE 1XKFA 3KPBA 5K22B 4IY0A 2YVZA 3GBYA 3LV9A 4L3VA 2QRDE 1O50A 1Y5HA 2RIHA 3FNAA 3HF7A 3T4NC 4P1GA 3TDHC 2D4ZA 2EMQA 3SL7A 3OCOA 4GQVA 4IYSA 2YZQA 2YVYA 2NYEA 4IY3A 3ORGA 3L2BA 5LXQA 5K23C 3FV6A 3LQNA 3FWRA 2RC3A 3OI8A 4P1OA 2PFIA 5MMZA 4DQWA 4FRYA 3L31A 4O9KA 2O16A 3KH5A 3PC4A 4NOCA 4IY4A 2UV4A 3LFZA 2QR1E 4L0DA 4GQYA 3DDJA 2QRCE 2OOXE 4L28A 4PCUA 3LHHA 3PC3A 4ESYA 5K24C 4GQWA 2UV5A 2NYCA 3KXRA 5K25C 2QLVC 5KS7A 2UV6A 1PVMA 2RIFA 3KPCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EF7 A;  4FXS A;  2UV7 A;  3K2V A;  2YZI A;  4HG0 A;  4L27 A;  3K6E A;  3TE5 C;  3I8N A;  2QH1 A;  4IY2 A;  4COO A;  1YAV A;  2QRE E;  2ZY9 A;  2OUX A;  3PC2 A;  5IIP A;  4UUU A;  2P9M A;  1PBJ A;  2YVX A;  3FWS A;  3OCM A;  4ESY B;  3KPD A;  3FHM A;  2OOY E;  1XKF A;  3KPB A;  5K22 B;  4IY0 A;  2YVZ A;  3GBY A;  3LV9 A;  4L3V A;  2QRD E;  1O50 A;  1Y5H A;  2RIH A;  3FNA A;  3HF7 A;  3T4N C;  4P1G A;  3TDH C;  2D4Z A;  2EMQ A;  3SL7 A;  3OCO A;  4GQV A;  4IYS A;  2YZQ A;  2YVY A;  2NYE A;  4IY3 A;  3ORG A;  3L2B A;  5LXQ A;  5K23 C;  3FV6 A;  3LQN A;  3FWR A;  2RC3 A;  3OI8 A;  4P1O A;  2PFI A;  5MMZ A;  4DQW A;  4FRY A;  3L31 A;  4O9K A;  2O16 A;  3KH5 A;  3PC4 A;  4NOC A;  4IY4 A;  2UV4 A;  3LFZ A;  2QR1 E;  4L0D A;  4GQY A;  3DDJ A;  2QRC E;  2OOX E;  4L28 A;  4PCU A;  3LHH A;  3PC3 A;  4ESY A;  5K24 C;  4GQW A;  2UV5 A;  2NYC A;  3KXR A;  5K25 C;  2QLV C;  5KS7 A;  2UV6 A;  1PVM A;  2RIF A;  3KPC A; 
#chains in the Genus database with same CATH topology
 2EF7 A;  4FXS A;  2UV7 A;  3K2V A;  2YZI A;  4HG0 A;  4L27 A;  3K6E A;  3TE5 C;  3I8N A;  2QH1 A;  4IY2 A;  4COO A;  1YAV A;  2QRE E;  2ZY9 A;  2OUX A;  2JA3 A;  3PC2 A;  5IIP A;  4UUU A;  2P9M A;  1PBJ A;  2YVX A;  2J9L A;  3FWS A;  3OCM A;  4ESY B;  3KPD A;  3FHM A;  2OOY E;  1XKF A;  3KPB A;  5K22 B;  4IY0 A;  2YVZ A;  3GBY A;  3LV9 A;  4L3V A;  2QRD E;  1O50 A;  1Y5H A;  2RIH A;  3FNA A;  3HF7 A;  3T4N C;  4P1G A;  3TDH C;  2D4Z A;  2EMQ A;  3SL7 A;  3OCO A;  4GQV A;  4IYS A;  2YZQ A;  2YVY A;  2NYE A;  4IY3 A;  3ORG A;  3L2B A;  5LXQ A;  5K23 C;  3FV6 A;  3LQN A;  3FWR A;  2RC3 A;  3OI8 A;  4P1O A;  2PFI A;  5MMZ A;  4DQW A;  4FRY A;  3L31 A;  4O9K A;  2O16 A;  3KH5 A;  3PC4 A;  4NOC A;  4IY4 A;  2UV4 A;  3LFZ A;  2QR1 E;  4L0D A;  4GQY A;  3DDJ A;  2QRC E;  2OOX E;  4L28 A;  4PCU A;  3LHH A;  3PC3 A;  4ESY A;  5K24 C;  4GQW A;  2UV5 A;  2NYC A;  3KXR A;  5K25 C;  2QLV C;  5KS7 A;  2UV6 A;  1PVM A;  2RIF A;  3KPC A; 
#chains in the Genus database with same CATH homology
 2EF7 A;  4FXS A;  2UV7 A;  3K2V A;  2YZI A;  4HG0 A;  4L27 A;  3K6E A;  3TE5 C;  3I8N A;  2QH1 A;  4IY2 A;  4COO A;  1YAV A;  2QRE E;  2ZY9 A;  2OUX A;  2JA3 A;  3PC2 A;  5IIP A;  4UUU A;  2P9M A;  1PBJ A;  2YVX A;  2J9L A;  3FWS A;  3OCM A;  4ESY B;  3KPD A;  3FHM A;  2OOY E;  1XKF A;  3KPB A;  5K22 B;  4IY0 A;  2YVZ A;  3GBY A;  3LV9 A;  4L3V A;  2QRD E;  1O50 A;  1Y5H A;  2RIH A;  3FNA A;  3HF7 A;  3T4N C;  4P1G A;  3TDH C;  2D4Z A;  2EMQ A;  3SL7 A;  3OCO A;  4GQV A;  4IYS A;  2YZQ A;  2YVY A;  2NYE A;  4IY3 A;  3ORG A;  3L2B A;  5LXQ A;  5K23 C;  3FV6 A;  3LQN A;  3FWR A;  2RC3 A;  3OI8 A;  4P1O A;  2PFI A;  5MMZ A;  4DQW A;  4FRY A;  3L31 A;  4O9K A;  2O16 A;  3KH5 A;  3PC4 A;  4NOC A;  4IY4 A;  2UV4 A;  3LFZ A;  2QR1 E;  4L0D A;  4GQY A;  3DDJ A;  2QRC E;  2OOX E;  4L28 A;  4PCU A;  3LHH A;  3PC3 A;  4ESY A;  5K24 C;  4GQW A;  2UV5 A;  2NYC A;  3KXR A;  5K25 C;  2QLV C;  5KS7 A;  2UV6 A;  1PVM A;  2RIF A;  3KPC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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