4IY4A

Structural and ligand binding properties of the bateman domain of human magnesium transporters cnnm2 and cnnm4
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
152
structure length
152
Chain Sequence
KEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVILEDVIEEIIKSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
rcsb
molecule tags Metal transport
source organism Homo sapiens
molecule keywords Metal transporter CNNM2
total genus 38
structure length 152
sequence length 152
chains with identical sequence C
ec nomenclature
pdb deposition date 2013-01-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 4iy4A00
2PFIA 2RC3A 4L3VA 3LV9A 5K23C 3DDJA 3L2BA 3L31A 2D4ZA 1YAVA 4GQYA 2YVXA 4GQWA 1O50A 4P1GA 3PC4A 3LQNA 1PVMA 5IIPA 2O16A 2QLVC 3K2VA 2OUXA 3PC2A 2UV5A 2QRDE 4COOA 4IY4A 5KS7A 3OCMA 5K24C 2NYEA 2OOXE 3I8NA 5K22B 4ESYA 2ZY9A 4NOCA 3LFZA 3OCOA 4PCUA 2RIFA 4IY2A 2YZIA 2OOYE 3KPDA 1XKFA 3SL7A 3FNAA 4HG0A 3K6EA 3LHHA 2P9MA 3HF7A 1Y5HA 3KXRA 3OI8A 2YVZA 2UV4A 4L0DA 4O9KA 4P1OA 3FWSA 3FV6A 5K25C 4FXSA 2RIHA 3TE5C 4FRYA 3KPCA 4L28A 3FHMA 3TDHC 2UV6A 3GBYA 4GQVA 4ESYB 3ORGA 2QH1A 3PC3A 4IY0A 3KH5A 2QRCE 3T4NC 2YZQA 5LXQA 5MMZA 2QREE 1PBJA 3KPBA 4UUUA 2EF7A 2EMQA 2UV7A 4IYSA 2YVYA 4IY3A 2QR1E 2NYCA 4L27A 3FWRA 4DQWA
chains in the Genus database with same CATH superfamily
2PFIA 2RC3A 4L3VA 3LV9A 5K23C 3DDJA 3L2BA 3L31A 2D4ZA 4GQYA 2JA3A 2YVXA 4GQWA 1O50A 4P1GA 3PC4A 3LQNA 1PVMA 5IIPA 2O16A 2QLVC 3K2VA 2OUXA 3PC2A 2UV5A 2QRDE 4COOA 4IY4A 5KS7A 3OCMA 5K24C 2NYEA 2OOXE 3I8NA 5K22B 4ESYA 2ZY9A 4NOCA 3LFZA 3OCOA 4L27A 4PCUA 2RIFA 4IY2A 2YZIA 2OOYE 3KPDA 1XKFA 2J9LA 3SL7A 3FNAA 4HG0A 3K6EA 3LHHA 2P9MA 3HF7A 1Y5HA 3KXRA 3OI8A 2YVZA 2UV4A 4L0DA 4O9KA 4P1OA 3FWSA 3FV6A 5K25C 4FXSA 2RIHA 3TE5C 4FRYA 3KPCA 4L28A 3FHMA 3TDHC 2UV6A 3GBYA 4GQVA 4ESYB 3ORGA 2QH1A 3PC3A 4IY0A 3KH5A 2QRCE 3T4NC 2YZQA 5LXQA 5MMZA 2QREE 1PBJA 3KPBA 4UUUA 2EF7A 2EMQA 2UV7A 4IYSA 2YVYA 4IY3A 2QR1E 2NYCA 1YAVA 3FWRA 4DQWA
chains in the Genus database with same CATH topology
2PFIA 2RC3A 4L3VA 3LV9A 5K23C 3DDJA 3L2BA 3L31A 2D4ZA 4GQYA 2JA3A 2YVXA 4GQWA 1O50A 4P1GA 3PC4A 3LQNA 1PVMA 5IIPA 2O16A 2QLVC 3K2VA 2OUXA 3PC2A 2UV5A 2QRDE 4COOA 4IY4A 5KS7A 3OCMA 5K24C 2NYEA 2OOXE 3I8NA 5K22B 4ESYA 2ZY9A 4NOCA 3LFZA 3OCOA 4L27A 4PCUA 2RIFA 4IY2A 2YZIA 2OOYE 3KPDA 1XKFA 2J9LA 3SL7A 3FNAA 4HG0A 3K6EA 3LHHA 2P9MA 3HF7A 1Y5HA 3KXRA 3OI8A 2YVZA 2UV4A 4L0DA 4O9KA 4P1OA 3FWSA 3FV6A 5K25C 4FXSA 2RIHA 3TE5C 4FRYA 3KPCA 4L28A 3FHMA 3TDHC 2UV6A 3GBYA 4GQVA 4ESYB 3ORGA 2QH1A 3PC3A 4IY0A 3KH5A 2QRCE 3T4NC 2YZQA 5LXQA 5MMZA 2QREE 1PBJA 3KPBA 4UUUA 2EF7A 2EMQA 2UV7A 4IYSA 2YVYA 4IY3A 2QR1E 2NYCA 1YAVA 3FWRA 4DQWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PFI A;  2RC3 A;  4L3V A;  3LV9 A;  5K23 C;  3DDJ A;  3L2B A;  3L31 A;  2D4Z A;  1YAV A;  4GQY A;  2YVX A;  4GQW A;  1O50 A;  4P1G A;  3PC4 A;  3LQN A;  1PVM A;  5IIP A;  2O16 A;  2QLV C;  3K2V A;  2OUX A;  3PC2 A;  2UV5 A;  2QRD E;  4COO A;  4IY4 A;  5KS7 A;  3OCM A;  5K24 C;  2NYE A;  2OOX E;  3I8N A;  5K22 B;  4ESY A;  2ZY9 A;  4NOC A;  3LFZ A;  3OCO A;  4PCU A;  2RIF A;  4IY2 A;  2YZI A;  2OOY E;  3KPD A;  1XKF A;  3SL7 A;  3FNA A;  4HG0 A;  3K6E A;  3LHH A;  2P9M A;  3HF7 A;  1Y5H A;  3KXR A;  3OI8 A;  2YVZ A;  2UV4 A;  4L0D A;  4O9K A;  4P1O A;  3FWS A;  3FV6 A;  5K25 C;  4FXS A;  2RIH A;  3TE5 C;  4FRY A;  3KPC A;  4L28 A;  3FHM A;  3TDH C;  2UV6 A;  3GBY A;  4GQV A;  4ESY B;  3ORG A;  2QH1 A;  3PC3 A;  4IY0 A;  3KH5 A;  2QRC E;  3T4N C;  2YZQ A;  5LXQ A;  5MMZ A;  2QRE E;  1PBJ A;  3KPB A;  4UUU A;  2EF7 A;  2EMQ A;  2UV7 A;  4IYS A;  2YVY A;  4IY3 A;  2QR1 E;  2NYC A;  4L27 A;  3FWR A;  4DQW A; 
#chains in the Genus database with same CATH topology
 2PFI A;  2RC3 A;  4L3V A;  3LV9 A;  5K23 C;  3DDJ A;  3L2B A;  3L31 A;  2D4Z A;  4GQY A;  2JA3 A;  2YVX A;  4GQW A;  1O50 A;  4P1G A;  3PC4 A;  3LQN A;  1PVM A;  5IIP A;  2O16 A;  2QLV C;  3K2V A;  2OUX A;  3PC2 A;  2UV5 A;  2QRD E;  4COO A;  4IY4 A;  5KS7 A;  3OCM A;  5K24 C;  2NYE A;  2OOX E;  3I8N A;  5K22 B;  4ESY A;  2ZY9 A;  4NOC A;  3LFZ A;  3OCO A;  4L27 A;  4PCU A;  2RIF A;  4IY2 A;  2YZI A;  2OOY E;  3KPD A;  1XKF A;  2J9L A;  3SL7 A;  3FNA A;  4HG0 A;  3K6E A;  3LHH A;  2P9M A;  3HF7 A;  1Y5H A;  3KXR A;  3OI8 A;  2YVZ A;  2UV4 A;  4L0D A;  4O9K A;  4P1O A;  3FWS A;  3FV6 A;  5K25 C;  4FXS A;  2RIH A;  3TE5 C;  4FRY A;  3KPC A;  4L28 A;  3FHM A;  3TDH C;  2UV6 A;  3GBY A;  4GQV A;  4ESY B;  3ORG A;  2QH1 A;  3PC3 A;  4IY0 A;  3KH5 A;  2QRC E;  3T4N C;  2YZQ A;  5LXQ A;  5MMZ A;  2QRE E;  1PBJ A;  3KPB A;  4UUU A;  2EF7 A;  2EMQ A;  2UV7 A;  4IYS A;  2YVY A;  4IY3 A;  2QR1 E;  2NYC A;  1YAV A;  3FWR A;  4DQW A; 
#chains in the Genus database with same CATH homology
 2PFI A;  2RC3 A;  4L3V A;  3LV9 A;  5K23 C;  3DDJ A;  3L2B A;  3L31 A;  2D4Z A;  4GQY A;  2JA3 A;  2YVX A;  4GQW A;  1O50 A;  4P1G A;  3PC4 A;  3LQN A;  1PVM A;  5IIP A;  2O16 A;  2QLV C;  3K2V A;  2OUX A;  3PC2 A;  2UV5 A;  2QRD E;  4COO A;  4IY4 A;  5KS7 A;  3OCM A;  5K24 C;  2NYE A;  2OOX E;  3I8N A;  5K22 B;  4ESY A;  2ZY9 A;  4NOC A;  3LFZ A;  3OCO A;  4L27 A;  4PCU A;  2RIF A;  4IY2 A;  2YZI A;  2OOY E;  3KPD A;  1XKF A;  2J9L A;  3SL7 A;  3FNA A;  4HG0 A;  3K6E A;  3LHH A;  2P9M A;  3HF7 A;  1Y5H A;  3KXR A;  3OI8 A;  2YVZ A;  2UV4 A;  4L0D A;  4O9K A;  4P1O A;  3FWS A;  3FV6 A;  5K25 C;  4FXS A;  2RIH A;  3TE5 C;  4FRY A;  3KPC A;  4L28 A;  3FHM A;  3TDH C;  2UV6 A;  3GBY A;  4GQV A;  4ESY B;  3ORG A;  2QH1 A;  3PC3 A;  4IY0 A;  3KH5 A;  2QRC E;  3T4N C;  2YZQ A;  5LXQ A;  5MMZ A;  2QRE E;  1PBJ A;  3KPB A;  4UUU A;  2EF7 A;  2EMQ A;  2UV7 A;  4IYS A;  2YVY A;  4IY3 A;  2QR1 E;  2NYC A;  1YAV A;  3FWR A;  4DQW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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