5MMZA

Structure of prl-1 in complex with the bateman domain of cnnm2
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
150
structure length
150
Chain Sequence
MEELNIIQGALELRTKTVEDVMTPLRDCFMITGEAILDFNTMSEIMESGYTRIPVFEGERSNIVDLLFVKDLAFVDPDDCTPLKTITKFYNHPLHFVFNDTKLDAMLEEFKKGKSHLAIVQRVNNEGEGDPFYEVLGIVTLEDVIEEIIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis of the Oncogenic Interaction of Phosphatase PRL-1 with the Magnesium Transporter CNNM2.
pubmed doi rcsb
molecule tags Metal transport
source organism Mus musculus
molecule keywords Metal transporter CNNM2
total genus 43
structure length 150
sequence length 150
ec nomenclature
pdb deposition date 2016-12-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00571 CBS CBS domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.580.10 Alpha Beta Roll CBS-domain CBS-domain 5mmzA00
3KPCA 3LFZA 2OOXE 2O16A 3K6EA 2OOYE 3FWRA 2UV7A 4UUUA 2QRDE 1PVMA 4NOCA 5K22B 4IY2A 2NYEA 3KPBA 1O50A 2QRCE 3FHMA 3K2VA 4L3VA 4GQYA 2YVZA 3LHHA 3PC2A 3OCMA 2EF7A 5KS7A 4O9KA 2QLVC 4ESYB 5LXQA 3LV9A 4HG0A 3OCOA 2PFIA 2YVXA 3SL7A 4L0DA 4IY4A 4P1GA 4IY3A 4IYSA 4FRYA 2EMQA 2QR1E 2RIFA 4FXSA 2UV5A 3T4NC 2YZQA 2YVYA 3PC3A 3OI8A 5K25C 3DDJA 4GQVA 3L31A 3HF7A 3L2BA 5K23C 3I8NA 2QH1A 1YAVA 2D4ZA 4ESYA 3TDHC 5MMZA 5IIPA 2YZIA 1Y5HA 4P1OA 3TE5C 3LQNA 3GBYA 4PCUA 5K24C 3KH5A 3PC4A 2OUXA 2P9MA 3FWSA 3KPDA 1PBJA 1XKFA 2QREE 2UV6A 4L28A 2NYCA 2UV4A 4COOA 2ZY9A 4IY0A 3FV6A 3KXRA 3ORGA 4L27A 4DQWA 2RIHA 2RC3A 3FNAA 4GQWA
chains in the Genus database with same CATH superfamily
3KPCA 3LFZA 2OOXE 2O16A 3K6EA 2OOYE 3FWRA 2UV7A 4UUUA 2QRDE 1PVMA 4NOCA 5K22B 4IY2A 2NYEA 2JA3A 3KPBA 1O50A 2QRCE 3FHMA 3K2VA 4L3VA 4GQYA 2YVZA 3LHHA 3PC2A 3OCMA 2EF7A 2J9LA 5KS7A 4O9KA 2QLVC 4ESYB 5LXQA 3LV9A 4HG0A 3OCOA 2PFIA 2YVXA 3SL7A 4L0DA 4IY4A 4P1GA 4IY3A 4IYSA 4FRYA 2EMQA 2QR1E 2RIFA 4FXSA 2UV5A 3T4NC 2YZQA 2YVYA 3PC3A 3OI8A 5K25C 3DDJA 4GQVA 3L31A 3HF7A 3L2BA 5K23C 3I8NA 2QH1A 1YAVA 2D4ZA 4ESYA 3TDHC 5MMZA 5IIPA 2YZIA 1Y5HA 4P1OA 3TE5C 3LQNA 3GBYA 4PCUA 5K24C 3KH5A 3PC4A 2OUXA 2P9MA 3FWSA 3KPDA 1PBJA 1XKFA 2QREE 2UV6A 4L28A 2NYCA 2UV4A 4COOA 2ZY9A 4IY0A 3FV6A 3KXRA 3ORGA 4L27A 4DQWA 2RIHA 2RC3A 3FNAA 4GQWA
chains in the Genus database with same CATH topology
3KPCA 3LFZA 2OOXE 2O16A 3K6EA 2OOYE 3FWRA 2UV7A 4UUUA 2QRDE 1PVMA 4NOCA 5K22B 4IY2A 2NYEA 2JA3A 3KPBA 1O50A 2QRCE 3FHMA 3K2VA 4L3VA 4GQYA 2YVZA 3LHHA 3PC2A 3OCMA 2EF7A 2J9LA 5KS7A 4O9KA 2QLVC 4ESYB 5LXQA 3LV9A 4HG0A 3OCOA 2PFIA 2YVXA 3SL7A 4L0DA 4IY4A 4P1GA 4IY3A 4IYSA 4FRYA 2EMQA 2QR1E 2RIFA 4FXSA 2UV5A 3T4NC 2YZQA 2YVYA 3PC3A 3OI8A 5K25C 3DDJA 4GQVA 3L31A 3HF7A 3L2BA 5K23C 3I8NA 2QH1A 1YAVA 2D4ZA 4ESYA 3TDHC 5MMZA 5IIPA 2YZIA 1Y5HA 4P1OA 3TE5C 3LQNA 3GBYA 4PCUA 5K24C 3KH5A 3PC4A 2OUXA 2P9MA 3FWSA 3KPDA 1PBJA 1XKFA 2QREE 2UV6A 4L28A 2NYCA 2UV4A 4COOA 2ZY9A 4IY0A 3FV6A 3KXRA 3ORGA 4L27A 4DQWA 2RIHA 2RC3A 3FNAA 4GQWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KPC A;  3LFZ A;  2OOX E;  2O16 A;  3K6E A;  2OOY E;  3FWR A;  2UV7 A;  4UUU A;  2QRD E;  1PVM A;  4NOC A;  5K22 B;  4IY2 A;  2NYE A;  3KPB A;  1O50 A;  2QRC E;  3FHM A;  3K2V A;  4L3V A;  4GQY A;  2YVZ A;  3LHH A;  3PC2 A;  3OCM A;  2EF7 A;  5KS7 A;  4O9K A;  2QLV C;  4ESY B;  5LXQ A;  3LV9 A;  4HG0 A;  3OCO A;  2PFI A;  2YVX A;  3SL7 A;  4L0D A;  4IY4 A;  4P1G A;  4IY3 A;  4IYS A;  4FRY A;  2EMQ A;  2QR1 E;  2RIF A;  4FXS A;  2UV5 A;  3T4N C;  2YZQ A;  2YVY A;  3PC3 A;  3OI8 A;  5K25 C;  3DDJ A;  4GQV A;  3L31 A;  3HF7 A;  3L2B A;  5K23 C;  3I8N A;  2QH1 A;  1YAV A;  2D4Z A;  4ESY A;  3TDH C;  5MMZ A;  5IIP A;  2YZI A;  1Y5H A;  4P1O A;  3TE5 C;  3LQN A;  3GBY A;  4PCU A;  5K24 C;  3KH5 A;  3PC4 A;  2OUX A;  2P9M A;  3FWS A;  3KPD A;  1PBJ A;  1XKF A;  2QRE E;  2UV6 A;  4L28 A;  2NYC A;  2UV4 A;  4COO A;  2ZY9 A;  4IY0 A;  3FV6 A;  3KXR A;  3ORG A;  4L27 A;  4DQW A;  2RIH A;  2RC3 A;  3FNA A;  4GQW A; 
#chains in the Genus database with same CATH topology
 3KPC A;  3LFZ A;  2OOX E;  2O16 A;  3K6E A;  2OOY E;  3FWR A;  2UV7 A;  4UUU A;  2QRD E;  1PVM A;  4NOC A;  5K22 B;  4IY2 A;  2NYE A;  2JA3 A;  3KPB A;  1O50 A;  2QRC E;  3FHM A;  3K2V A;  4L3V A;  4GQY A;  2YVZ A;  3LHH A;  3PC2 A;  3OCM A;  2EF7 A;  2J9L A;  5KS7 A;  4O9K A;  2QLV C;  4ESY B;  5LXQ A;  3LV9 A;  4HG0 A;  3OCO A;  2PFI A;  2YVX A;  3SL7 A;  4L0D A;  4IY4 A;  4P1G A;  4IY3 A;  4IYS A;  4FRY A;  2EMQ A;  2QR1 E;  2RIF A;  4FXS A;  2UV5 A;  3T4N C;  2YZQ A;  2YVY A;  3PC3 A;  3OI8 A;  5K25 C;  3DDJ A;  4GQV A;  3L31 A;  3HF7 A;  3L2B A;  5K23 C;  3I8N A;  2QH1 A;  1YAV A;  2D4Z A;  4ESY A;  3TDH C;  5MMZ A;  5IIP A;  2YZI A;  1Y5H A;  4P1O A;  3TE5 C;  3LQN A;  3GBY A;  4PCU A;  5K24 C;  3KH5 A;  3PC4 A;  2OUX A;  2P9M A;  3FWS A;  3KPD A;  1PBJ A;  1XKF A;  2QRE E;  2UV6 A;  4L28 A;  2NYC A;  2UV4 A;  4COO A;  2ZY9 A;  4IY0 A;  3FV6 A;  3KXR A;  3ORG A;  4L27 A;  4DQW A;  2RIH A;  2RC3 A;  3FNA A;  4GQW A; 
#chains in the Genus database with same CATH homology
 3KPC A;  3LFZ A;  2OOX E;  2O16 A;  3K6E A;  2OOY E;  3FWR A;  2UV7 A;  4UUU A;  2QRD E;  1PVM A;  4NOC A;  5K22 B;  4IY2 A;  2NYE A;  2JA3 A;  3KPB A;  1O50 A;  2QRC E;  3FHM A;  3K2V A;  4L3V A;  4GQY A;  2YVZ A;  3LHH A;  3PC2 A;  3OCM A;  2EF7 A;  2J9L A;  5KS7 A;  4O9K A;  2QLV C;  4ESY B;  5LXQ A;  3LV9 A;  4HG0 A;  3OCO A;  2PFI A;  2YVX A;  3SL7 A;  4L0D A;  4IY4 A;  4P1G A;  4IY3 A;  4IYS A;  4FRY A;  2EMQ A;  2QR1 E;  2RIF A;  4FXS A;  2UV5 A;  3T4N C;  2YZQ A;  2YVY A;  3PC3 A;  3OI8 A;  5K25 C;  3DDJ A;  4GQV A;  3L31 A;  3HF7 A;  3L2B A;  5K23 C;  3I8N A;  2QH1 A;  1YAV A;  2D4Z A;  4ESY A;  3TDH C;  5MMZ A;  5IIP A;  2YZI A;  1Y5H A;  4P1O A;  3TE5 C;  3LQN A;  3GBY A;  4PCU A;  5K24 C;  3KH5 A;  3PC4 A;  2OUX A;  2P9M A;  3FWS A;  3KPD A;  1PBJ A;  1XKF A;  2QRE E;  2UV6 A;  4L28 A;  2NYC A;  2UV4 A;  4COO A;  2ZY9 A;  4IY0 A;  3FV6 A;  3KXR A;  3ORG A;  4L27 A;  4DQW A;  2RIH A;  2RC3 A;  3FNA A;  4GQW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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