3HQI | Genus

Total Genus 67

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	67
sequence length	304
structure length	294
Chain Sequence	GSKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSNDKLKWCLRVNPKGLDSKDYLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding, ligase
source organism	Homo sapiens
publication title	Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. pubmed doi rcsb
molecule keywords	Speckle-type POZ protein
total genus	67
structure length	294
sequence length	304
chains with identical sequence	B
ec nomenclature
pdb deposition date	2009-06-07

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00651	BTB	BTB/POZ domain
A	PF00917	MATH	MATH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.210.10	Mainly Beta	Sandwich	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	3hqiA01
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	3hqiA02

3M52A 4I7CA 4W9HH 4BGCA 3IVQA 3MQRA 3LUTB 1FQVB 4GWNA 4J8ZA 4I7BA 3C6NA 2P1QA 3BIMA 1CA9A 4B9KB 4GJHA 1DSXA 2F1WA 1LM8C 1ZMSA 1R28A 4C9ZA 1FLKA 4W9EB 4UYIA 4W9CB 4W9GB 2Q81A 1LB4A 3V7DA 5E1TA 4W9KB 1LB5A 1R29A 5H9MA 4N9F5 1P22B 4CXJA 3ZTCB 2C9WC 3LBZA 4U77A 4CA1A 3ZTDB 2VKPA 4CXTA 2PPIA 4UIJA 4WQOC 3HVEA 3HTMA 2JZ3C 1R2BA 1BUOA 4B9KE 2NN2A 2F1YA 3M8VA 1CA4A 3OGMA 5LLIB 4W9FB 2FOOA 2E32B 2A25A 4U2NA 4U2MA 1D00A 2MA9C 2FOPA 4W9DB 3WSOB 2P1MA 1CZZA 2AN6A 2OVRA 4JTAB 1KZZA 3HQIA 1YY6A 4APFA 2E31B 2FOJA 5FTAA 5BO4C 2ASTA 4CP3A 3ZNGB 4I6JC 3M4TA 3ZJBA 4AJYC 3HQLA 1FS2B 1EOFA 1HV2A 5JH5B 4CXIA 1EODA 3I3NA 1RF3A 3IVVA 3B84A 4GHUA 4O1VA 3E4UA 3C6OA 1YZEA 3ZRFB 4KG9A 4I7DA 1NN7A 3DRZA 2OVQA 1CS3A 2NZ0B 1CZYA 2IF5A 2I2RA 3HVEB 4ZOUA 4K8UA 2IHCA 4AWJB 1F3VB 3ZRCB 4YSIA 2GKWA 2FNJC 2P1OA 5BXHA 4JJQA 1EOEA 2YY9A 1EXBE 4GWMA 2R9RB 1L0AA 1FS1B 2P1NA 4EOZA 3OGLA 3ZUNB 3M5BA 3HU6A 3L2OA 1QDWA 2CR2A 3LNMB 4W9LB 2VPKA 5DAFA 4B95B 4M4EA 4JTDB 2XXNA 1QDVA 5DADA 5BXDA 3OHUA 3HQHA 1D0JA 1LDKD 3HSVA 2A79B 3MKSA 5EUPA 5H7HA 5IBKA 2OVPA 1D01A 2P1PA 1T1DA 1K2FA 1VCBB 5A15A 3ZKJB 4X3GA 4W9JB 1LQBB 2Z8HA 4BKTB 3HQMA 1LB6A 3C6PA 5BXBA 1FLLA 4AP2A 1D0AA 3MQSC 4W9IB 5HZGC 4CRHA 3FKCA 3GA1A 1NEXA 4BKSB 4HXIA 4JGHC 1S1GA 5A6RA 3DCGB 3OHVA 5HYWB 1A68A 4W9HB 3OGKA 4JTCB 1QSCA 2F1XA 2F1ZA 2ASSA 4Z8MA 5H7GA 3IVBA 3KVTA 2IZVC
chains in the Genus database with same CATH superfamily

3M52A 4I7CA 4W9HH 4BGCA 3IVQA 3MQRA 3LUTB 1FQVB 4GWNA 4J8ZA 4I7BA 3C6NA 2P1QA 3BIMA 1CA9A 4B9KB 4GJHA 1DSXA 2F1WA 1LM8C 1ZMSA 1R28A 4C9ZA 1FLKA 4W9EB 4UYIA 4W9CB 4W9GB 2Q81A 1LB4A 3V7DA 5E1TA 4W9KB 1LB5A 1R29A 5H9MA 4N9F5 1P22B 4CXJA 3ZTCB 2C9WC 3LBZA 4U77A 4CA1A 3ZTDB 2VKPA 4CXTA 2PPIA 4UIJA 4WQOC 3HVEA 3HTMA 2JZ3C 1R2BA 1BUOA 4B9KE 2NN2A 2F1YA 3M8VA 1CA4A 3OGMA 5LLIB 4W9FB 2FOOA 2E32B 2A25A 4U2NA 4U2MA 1D00A 2MA9C 2FOPA 4W9DB 3WSOB 2P1MA 1CZZA 2AN6A 2OVRA 4JTAB 1KZZA 3HQIA 1YY6A 4APFA 2E31B 2FOJA 5FTAA 5BO4C 3DRYA 2ASTA 4CP3A 3ZNGB 4I6JC 3M4TA 3ZJBA 4AJYC 3HQLA 1FS2B 1EOFA 1HV2A 5JH5B 4CXIA 4ZGCA 1EODA 3I3NA 1RF3A 3IVVA 3B84A 4GHUA 4O1VA 3E4UA 3C6OA 1YZEA 3ZRFB 4KG9A 4I7DA 1NN7A 3DRZA 2OVQA 1CS3A 2NZ0B 1CZYA 2IF5A 2I2RA 3HVEB 4ZOUA 4K8UA 2IHCA 4AWJB 1F3VB 3ZRCB 4YSIA 2GKWA 2FNJC 2P1OA 5BXHA 4JJQA 1EOEA 2YY9A 1EXBE 4GWMA 2R9RB 1L0AA 1FS1B 2P1NA 4EOZA 3OGLA 3ZUNB 3M5BA 3HU6A 3L2OA 1QDWA 2CR2A 3LNMB 4W9LB 2VPKA 5DAFA 4B95B 3DRXA 4M4EA 4JTDB 2XXNA 1QDVA 5DADA 5BXDA 3OHUA 3HQHA 1D0JA 1LDKD 3HSVA 2A79B 3MKSA 5EUPA 5H7HA 5IBKA 2OVPA 1D01A 2P1PA 1T1DA 1K2FA 4YY8A 1VCBB 5A15A 3ZKJB 4X3GA 4W9JB 1LQBB 2Z8HA 4BKTB 3HQMA 1LB6A 3C6PA 5BXBA 1FLLA 4AP2A 1D0AA 3MQSC 4W9IB 5HZGC 4CRHA 3FKCA 3GA1A 1NEXA 4BKSB 4HXIA 4JGHC 1S1GA 5A6RA 3DCGB 3OHVA 5HYWB 1A68A 4W9HB 3OGKA 4JTCB 1QSCA 2F1XA 2F1ZA 2ASSA 4Z8MA 5H7GA 3IVBA 3KVTA 2IZVC
chains in the Genus database with same CATH topology

3M52A 4I7CA 4W9HH 4BGCA 3IVQA 3MQRA 3LUTB 1FQVB 4GWNA 4J8ZA 4I7BA 3C6NA 2P1QA 3BIMA 1CA9A 4B9KB 4GJHA 1DSXA 2F1WA 1LM8C 1ZMSA 1R28A 4C9ZA 1FLKA 4W9EB 4UYIA 4W9CB 4W9GB 2Q81A 1LB4A 3V7DA 5E1TA 4W9KB 1LB5A 1R29A 5H9MA 4N9F5 1P22B 4CXJA 3ZTCB 2C9WC 3LBZA 4U77A 4CA1A 3ZTDB 2VKPA 4CXTA 2PPIA 4UIJA 4WQOC 3HVEA 3HTMA 2JZ3C 1R2BA 1BUOA 4B9KE 2NN2A 2F1YA 3M8VA 1CA4A 3OGMA 5LLIB 4W9FB 2FOOA 2E32B 2A25A 4U2NA 4U2MA 1D00A 2MA9C 2FOPA 4W9DB 3WSOB 2P1MA 1CZZA 2AN6A 2OVRA 4JTAB 1KZZA 3HQIA 1YY6A 4APFA 2E31B 2FOJA 5FTAA 5BO4C 3DRYA 2ASTA 4CP3A 3ZNGB 4I6JC 3M4TA 3ZJBA 4AJYC 3HQLA 1FS2B 1EOFA 1HV2A 5JH5B 4CXIA 4ZGCA 1EODA 3I3NA 1RF3A 3IVVA 3B84A 4GHUA 4O1VA 3E4UA 3C6OA 1YZEA 3ZRFB 4KG9A 4I7DA 1NN7A 3DRZA 2OVQA 1CS3A 2NZ0B 1CZYA 2IF5A 2I2RA 3HVEB 4ZOUA 4K8UA 2IHCA 4AWJB 1F3VB 3ZRCB 4YSIA 2GKWA 2FNJC 2P1OA 5BXHA 4JJQA 1EOEA 2YY9A 1EXBE 4GWMA 2R9RB 1L0AA 1FS1B 2P1NA 4EOZA 3OGLA 3ZUNB 3M5BA 3HU6A 3L2OA 1QDWA 2CR2A 3LNMB 4W9LB 2VPKA 5DAFA 4B95B 3DRXA 4M4EA 4JTDB 2XXNA 1QDVA 5DADA 5BXDA 3OHUA 3HQHA 1D0JA 1LDKD 3HSVA 2A79B 3MKSA 5EUPA 5H7HA 5IBKA 2OVPA 1D01A 2P1PA 1T1DA 1K2FA 4YY8A 1VCBB 5A15A 3ZKJB 4X3GA 4W9JB 1LQBB 2Z8HA 4BKTB 3HQMA 1LB6A 3C6PA 5BXBA 1FLLA 4AP2A 1D0AA 3MQSC 4W9IB 5HZGC 4CRHA 3FKCA 3GA1A 1NEXA 4BKSB 4HXIA 4JGHC 1S1GA 5A6RA 3DCGB 3OHVA 5HYWB 1A68A 4W9HB 3OGKA 4JTCB 1QSCA 2F1XA 2F1ZA 2ASSA 4Z8MA 5H7GA 3IVBA 3KVTA 2IZVC
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3M52 A;  4I7C A;  4W9H H;  4BGC A;  3IVQ A;  3MQR A;  3LUT B;  1FQV B;  4GWN A;  4J8Z A;  4I7B A;  3C6N A;  2P1Q A;  3BIM A;  1CA9 A;  4B9K B;  4GJH A;  1DSX A;  2F1W A;  1LM8 C;  1ZMS A;  1R28 A;  4C9Z A;  1FLK A;  4W9E B;  4UYI A;  4W9C B;  4W9G B;  2Q81 A;  1LB4 A;  3V7D A;  5E1T A;  4W9K B;  1LB5 A;  1R29 A;  5H9M A;  4N9F 5;  1P22 B;  4CXJ A;  3ZTC B;  2C9W C;  3LBZ A;  4U77 A;  4CA1 A;  3ZTD B;  2VKP A;  4CXT A;  2PPI A;  4UIJ A;  4WQO C;  3HVE A;  3HTM A;  2JZ3 C;  1R2B A;  1BUO A;  4B9K E;  2NN2 A;  2F1Y A;  3M8V A;  1CA4 A;  3OGM A;  5LLI B;  4W9F B;  2FOO A;  2E32 B;  2A25 A;  4U2N A;  4U2M A;  1D00 A;  2MA9 C;  2FOP A;  4W9D B;  3WSO B;  2P1M A;  1CZZ A;  2AN6 A;  2OVR A;  4JTA B;  1KZZ A;  3HQI A;  1YY6 A;  4APF A;  2E31 B;  2FOJ A;  5FTA A;  5BO4 C;  2AST A;  4CP3 A;  3ZNG B;  4I6J C;  3M4T A;  3ZJB A;  4AJY C;  3HQL A;  1FS2 B;  1EOF A;  1HV2 A;  5JH5 B;  4CXI A;  1EOD A;  3I3N A;  1RF3 A;  3IVV A;  3B84 A;  4GHU A;  4O1V A;  3E4U A;  3C6O A;  1YZE A;  3ZRF B;  4KG9 A;  4I7D A;  1NN7 A;  3DRZ A;  2OVQ A;  1CS3 A;  2NZ0 B;  1CZY A;  2IF5 A;  2I2R A;  3HVE B;  4ZOU A;  4K8U A;  2IHC A;  4AWJ B;  1F3V B;  3ZRC B;  4YSI A;  2GKW A;  2FNJ C;  2P1O A;  5BXH A;  4JJQ A;  1EOE A;  2YY9 A;  1EXB E;  4GWM A;  2R9R B;  1L0A A;  1FS1 B;  2P1N A;  4EOZ A;  3OGL A;  3ZUN B;  3M5B A;  3HU6 A;  3L2O A;  1QDW A;  2CR2 A;  3LNM B;  4W9L B;  2VPK A;  5DAF A;  4B95 B;  4M4E A;  4JTD B;  2XXN A;  1QDV A;  5DAD A;  5BXD A;  3OHU A;  3HQH A;  1D0J A;  1LDK D;  3HSV A;  2A79 B;  3MKS A;  5EUP A;  5H7H A;  5IBK A;  2OVP A;  1D01 A;  2P1P A;  1T1D A;  1K2F A;  1VCB B;  5A15 A;  3ZKJ B;  4X3G A;  4W9J B;  1LQB B;  2Z8H A;  4BKT B;  3HQM A;  1LB6 A;  3C6P A;  5BXB A;  1FLL A;  4AP2 A;  1D0A A;  3MQS C;  4W9I B;  5HZG C;  4CRH A;  3FKC A;  3GA1 A;  1NEX A;  4BKS B;  4HXI A;  4JGH C;  1S1G A;  5A6R A;  3DCG B;  3OHV A;  5HYW B;  1A68 A;  4W9H B;  3OGK A;  4JTC B;  1QSC A;  2F1X A;  2F1Z A;  2ASS A;  4Z8M A;  5H7G A;  3IVB A;  3KVT A;  2IZV C; 
#chains in the Genus database with same CATH topology
 3M52 A;  4I7C A;  4W9H H;  4BGC A;  3IVQ A;  3MQR A;  3LUT B;  1FQV B;  4GWN A;  4J8Z A;  4I7B A;  3C6N A;  2P1Q A;  3BIM A;  1CA9 A;  4B9K B;  4GJH A;  1DSX A;  2F1W A;  1LM8 C;  1ZMS A;  1R28 A;  4C9Z A;  1FLK A;  4W9E B;  4UYI A;  4W9C B;  4W9G B;  2Q81 A;  1LB4 A;  3V7D A;  5E1T A;  4W9K B;  1LB5 A;  1R29 A;  5H9M A;  4N9F 5;  1P22 B;  4CXJ A;  3ZTC B;  2C9W C;  3LBZ A;  4U77 A;  4CA1 A;  3ZTD B;  2VKP A;  4CXT A;  2PPI A;  4UIJ A;  4WQO C;  3HVE A;  3HTM A;  2JZ3 C;  1R2B A;  1BUO A;  4B9K E;  2NN2 A;  2F1Y A;  3M8V A;  1CA4 A;  3OGM A;  5LLI B;  4W9F B;  2FOO A;  2E32 B;  2A25 A;  4U2N A;  4U2M A;  1D00 A;  2MA9 C;  2FOP A;  4W9D B;  3WSO B;  2P1M A;  1CZZ A;  2AN6 A;  2OVR A;  4JTA B;  1KZZ A;  3HQI A;  1YY6 A;  4APF A;  2E31 B;  2FOJ A;  5FTA A;  5BO4 C;  3DRY A;  2AST A;  4CP3 A;  3ZNG B;  4I6J C;  3M4T A;  3ZJB A;  4AJY C;  3HQL A;  1FS2 B;  1EOF A;  1HV2 A;  5JH5 B;  4CXI A;  4ZGC A;  1EOD A;  3I3N A;  1RF3 A;  3IVV A;  3B84 A;  4GHU A;  4O1V A;  3E4U A;  3C6O A;  1YZE A;  3ZRF B;  4KG9 A;  4I7D A;  1NN7 A;  3DRZ A;  2OVQ A;  1CS3 A;  2NZ0 B;  1CZY A;  2IF5 A;  2I2R A;  3HVE B;  4ZOU A;  4K8U A;  2IHC A;  4AWJ B;  1F3V B;  3ZRC B;  4YSI A;  2GKW A;  2FNJ C;  2P1O A;  5BXH A;  4JJQ A;  1EOE A;  2YY9 A;  1EXB E;  4GWM A;  2R9R B;  1L0A A;  1FS1 B;  2P1N A;  4EOZ A;  3OGL A;  3ZUN B;  3M5B A;  3HU6 A;  3L2O A;  1QDW A;  2CR2 A;  3LNM B;  4W9L B;  2VPK A;  5DAF A;  4B95 B;  3DRX A;  4M4E A;  4JTD B;  2XXN A;  1QDV A;  5DAD A;  5BXD A;  3OHU A;  3HQH A;  1D0J A;  1LDK D;  3HSV A;  2A79 B;  3MKS A;  5EUP A;  5H7H A;  5IBK A;  2OVP A;  1D01 A;  2P1P A;  1T1D A;  1K2F A;  4YY8 A;  1VCB B;  5A15 A;  3ZKJ B;  4X3G A;  4W9J B;  1LQB B;  2Z8H A;  4BKT B;  3HQM A;  1LB6 A;  3C6P A;  5BXB A;  1FLL A;  4AP2 A;  1D0A A;  3MQS C;  4W9I B;  5HZG C;  4CRH A;  3FKC A;  3GA1 A;  1NEX A;  4BKS B;  4HXI A;  4JGH C;  1S1G A;  5A6R A;  3DCG B;  3OHV A;  5HYW B;  1A68 A;  4W9H B;  3OGK A;  4JTC B;  1QSC A;  2F1X A;  2F1Z A;  2ASS A;  4Z8M A;  5H7G A;  3IVB A;  3KVT A;  2IZV C; 
#chains in the Genus database with same CATH homology
 3M52 A;  4I7C A;  4W9H H;  4BGC A;  3IVQ A;  3MQR A;  3LUT B;  1FQV B;  4GWN A;  4J8Z A;  4I7B A;  3C6N A;  2P1Q A;  3BIM A;  1CA9 A;  4B9K B;  4GJH A;  1DSX A;  2F1W A;  1LM8 C;  1ZMS A;  1R28 A;  4C9Z A;  1FLK A;  4W9E B;  4UYI A;  4W9C B;  4W9G B;  2Q81 A;  1LB4 A;  3V7D A;  5E1T A;  4W9K B;  1LB5 A;  1R29 A;  5H9M A;  4N9F 5;  1P22 B;  4CXJ A;  3ZTC B;  2C9W C;  3LBZ A;  4U77 A;  4CA1 A;  3ZTD B;  2VKP A;  4CXT A;  2PPI A;  4UIJ A;  4WQO C;  3HVE A;  3HTM A;  2JZ3 C;  1R2B A;  1BUO A;  4B9K E;  2NN2 A;  2F1Y A;  3M8V A;  1CA4 A;  3OGM A;  5LLI B;  4W9F B;  2FOO A;  2E32 B;  2A25 A;  4U2N A;  4U2M A;  1D00 A;  2MA9 C;  2FOP A;  4W9D B;  3WSO B;  2P1M A;  1CZZ A;  2AN6 A;  2OVR A;  4JTA B;  1KZZ A;  3HQI A;  1YY6 A;  4APF A;  2E31 B;  2FOJ A;  5FTA A;  5BO4 C;  3DRY A;  2AST A;  4CP3 A;  3ZNG B;  4I6J C;  3M4T A;  3ZJB A;  4AJY C;  3HQL A;  1FS2 B;  1EOF A;  1HV2 A;  5JH5 B;  4CXI A;  4ZGC A;  1EOD A;  3I3N A;  1RF3 A;  3IVV A;  3B84 A;  4GHU A;  4O1V A;  3E4U A;  3C6O A;  1YZE A;  3ZRF B;  4KG9 A;  4I7D A;  1NN7 A;  3DRZ A;  2OVQ A;  1CS3 A;  2NZ0 B;  1CZY A;  2IF5 A;  2I2R A;  3HVE B;  4ZOU A;  4K8U A;  2IHC A;  4AWJ B;  1F3V B;  3ZRC B;  4YSI A;  2GKW A;  2FNJ C;  2P1O A;  5BXH A;  4JJQ A;  1EOE A;  2YY9 A;  1EXB E;  4GWM A;  2R9R B;  1L0A A;  1FS1 B;  2P1N A;  4EOZ A;  3OGL A;  3ZUN B;  3M5B A;  3HU6 A;  3L2O A;  1QDW A;  2CR2 A;  3LNM B;  4W9L B;  2VPK A;  5DAF A;  4B95 B;  3DRX A;  4M4E A;  4JTD B;  2XXN A;  1QDV A;  5DAD A;  5BXD A;  3OHU A;  3HQH A;  1D0J A;  1LDK D;  3HSV A;  2A79 B;  3MKS A;  5EUP A;  5H7H A;  5IBK A;  2OVP A;  1D01 A;  2P1P A;  1T1D A;  1K2F A;  4YY8 A;  1VCB B;  5A15 A;  3ZKJ B;  4X3G A;  4W9J B;  1LQB B;  2Z8H A;  4BKT B;  3HQM A;  1LB6 A;  3C6P A;  5BXB A;  1FLL A;  4AP2 A;  1D0A A;  3MQS C;  4W9I B;  5HZG C;  4CRH A;  3FKC A;  3GA1 A;  1NEX A;  4BKS B;  4HXI A;  4JGH C;  1S1G A;  5A6R A;  3DCG B;  3OHV A;  5HYW B;  1A68 A;  4W9H B;  3OGK A;  4JTC B;  1QSC A;  2F1X A;  2F1Z A;  2ASS A;  4Z8M A;  5H7G A;  3IVB A;  3KVT A;  2IZV C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3HQIA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations