3HQIA

Structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1
Total Genus 67
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
304
structure length
294
Chain Sequence
GSKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSNDKLKWCLRVNPKGLDSKDYLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
pubmed doi rcsb
molecule tags Protein binding, ligase
source organism Homo sapiens
molecule keywords Speckle-type POZ protein
total genus 67
structure length 294
sequence length 304
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00651 BTB BTB/POZ domain
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 3hqiA01
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 3hqiA02
1D01A 1KZZA 5H9MA 1CA4A 4I6JC 5HYWB 2OVQA 4I7CA 2IZVC 4UIJA 1YZEA 4CXJA 2P1MA 5IBKA 5EUPA 2FOJA 3OHVA 3E4UA 1EOFA 3DRZA 4W9LB 3HQMA 1DSXA 2JZ3C 4HXIA 3BIMA 2OVPA 2YY9A 2E31B 1RF3A 1CS3A 3HVEA 5H7HA 2ASSA 1BUOA 3MQSC 4U2NA 4C9ZA 4UYIA 2ASTA 1EODA 3C6OA 5A15A 1FS1B 2I2RA 1F3VB 1YY6A 2FOPA 1QSCA 1FLKA 2F1YA 2VKPA 3HQLA 4YSIA 1VCBB 2VPKA 4W9JB 3ZNGB 1R29A 3HQHA 2Q81A 4X3GA 3M8VA 4Z8MA 3ZRFB 5A6RA 5BXHA 2NN2A 3GA1A 1CZYA 4J8ZA 3OGLA 4ZOUA 4KG9A 1LQBB 2F1WA 2NZ0B 2XXNA 3OGKA 1D0JA 4JJQA 3LBZA 5FTAA 2P1QA 1LB4A 1CZZA 4GHUA 4N9F5 4JTAB 2FNJC 1A68A 2F1XA 5JH5B 4APFA 1T1DA 4W9HH 3LUTB 1S1GA 4JTCB 3IVVA 4W9GB 5E1TA 4U77A 1D00A 3HQIA 1QDWA 4M4EA 4K8UA 4W9HB 3HTMA 5DADA 1LB5A 3C6PA 1ZMSA 3ZUNB 4BKSB 2AN6A 2R9RB 3ZTCB 4B9KB 3HU6A 5BXDA 2C9WC 4JGHC 3OGMA 3ZRCB 1FLLA 3HSVA 3V7DA 2E32B 2OVRA 1NN7A 2IF5A 2GKWA 2IHCA 2P1NA 3HVEB 4GWNA 1HV2A 1FQVB 2A25A 2PPIA 5BXBA 3ZKJB 2A79B 3DCGB 4W9KB 3B84A 4GJHA 1R2BA 3OHUA 4BKTB 5H7GA 4BGCA 4CXIA 4EOZA 2F1ZA 5DAFA 2Z8HA 4CP3A 3MQRA 4CA1A 4I7DA 4AP2A 1CA9A 3C6NA 3MKSA 3IVQA 4I7BA 3KVTA 3IVBA 4W9FB 3ZJBA 2CR2A 4AJYC 3FKCA 4CXTA 1R28A 3LNMB 4JTDB 1P22B 4W9IB 1QDVA 4O1VA 4B95B 2P1OA 4B9KE 5HZGC 1NEXA 3M5BA 5LLIB 2MA9C 4W9DB 1EXBE 4AWJB 3M4TA 3ZTDB 2FOOA 1EOEA 3L2OA 1LB6A 1LDKD 4WQOC 4GWMA 2P1PA 3WSOB 1LM8C 1K2FA 1L0AA 3I3NA 3M52A 1D0AA 4CRHA 4W9EB 4U2MA 5BO4C 1FS2B 4W9CB
chains in the Genus database with same CATH superfamily
1D01A 1KZZA 5H9MA 1CA4A 4I6JC 5HYWB 2OVQA 4I7CA 2IZVC 4UIJA 1YZEA 4CXJA 2P1MA 5IBKA 5EUPA 2FOJA 3OHVA 3E4UA 1EOFA 3DRZA 4W9LB 3HQMA 1DSXA 2JZ3C 4HXIA 3BIMA 2OVPA 2YY9A 2E31B 1RF3A 1CS3A 3HVEA 5H7HA 2ASSA 1BUOA 3MQSC 4U2NA 4C9ZA 4UYIA 2ASTA 1EODA 3C6OA 5A15A 1FS1B 2I2RA 1F3VB 1YY6A 2FOPA 1QSCA 1FLKA 2F1YA 2VKPA 3HQLA 4YSIA 1VCBB 2VPKA 4W9JB 3ZNGB 1R29A 3HQHA 2Q81A 4X3GA 3M8VA 4Z8MA 3ZRFB 5A6RA 5BXHA 2NN2A 3GA1A 1CZYA 4J8ZA 3OGLA 4ZOUA 4KG9A 1LQBB 2F1WA 2NZ0B 2XXNA 3OGKA 1D0JA 4JJQA 3LBZA 5FTAA 4YY8A 2P1QA 1LB4A 1CZZA 4GHUA 4N9F5 4JTAB 4ZGCA 2FNJC 1A68A 2F1XA 5JH5B 4APFA 1T1DA 4W9HH 3LUTB 1S1GA 4JTCB 3IVVA 4W9GB 5E1TA 4U77A 1D00A 3HQIA 1QDWA 4M4EA 4K8UA 4W9HB 3HTMA 5DADA 1LB5A 3C6PA 1ZMSA 3ZUNB 4BKSB 2AN6A 2R9RB 3ZTCB 4B9KB 3HU6A 5BXDA 2C9WC 4JGHC 3OGMA 3ZRCB 1FLLA 3HSVA 3V7DA 2E32B 2OVRA 1NN7A 2IF5A 2GKWA 2IHCA 2P1NA 3HVEB 4GWNA 1HV2A 1FQVB 2A25A 2PPIA 5BXBA 3ZKJB 2A79B 3DCGB 4W9KB 3B84A 4GJHA 1R2BA 3OHUA 4BKTB 5H7GA 4BGCA 4CXIA 4EOZA 2F1ZA 5DAFA 2Z8HA 4CP3A 3MQRA 4CA1A 4I7DA 4AP2A 1CA9A 3C6NA 3MKSA 3IVQA 4I7BA 3KVTA 3IVBA 4W9FB 3ZJBA 2CR2A 4AJYC 3FKCA 4CXTA 1R28A 3LNMB 4JTDB 1P22B 4W9IB 1QDVA 4O1VA 4B95B 2P1OA 4B9KE 5HZGC 1NEXA 3DRXA 3M5BA 5LLIB 2MA9C 3DRYA 4W9DB 1EXBE 4AWJB 3M4TA 3ZTDB 2FOOA 1EOEA 3L2OA 1LB6A 1LDKD 4WQOC 4GWMA 2P1PA 3WSOB 1LM8C 1K2FA 1L0AA 3I3NA 3M52A 1D0AA 4CRHA 4W9EB 4U2MA 5BO4C 1FS2B 4W9CB
chains in the Genus database with same CATH topology
1D01A 1KZZA 5H9MA 1CA4A 4I6JC 5HYWB 2OVQA 4I7CA 2IZVC 4UIJA 1YZEA 4CXJA 2P1MA 5IBKA 5EUPA 2FOJA 3OHVA 3E4UA 1EOFA 3DRZA 4W9LB 3HQMA 1DSXA 2JZ3C 4HXIA 3BIMA 2OVPA 2YY9A 2E31B 1RF3A 1CS3A 3HVEA 5H7HA 2ASSA 1BUOA 3MQSC 4U2NA 4C9ZA 4UYIA 2ASTA 1EODA 3C6OA 5A15A 1FS1B 2I2RA 1F3VB 1YY6A 2FOPA 1QSCA 1FLKA 2F1YA 2VKPA 3HQLA 4YSIA 1VCBB 2VPKA 4W9JB 3ZNGB 1R29A 3HQHA 2Q81A 4X3GA 3M8VA 4Z8MA 3ZRFB 5A6RA 5BXHA 2NN2A 3GA1A 1CZYA 4J8ZA 3OGLA 4ZOUA 4KG9A 1LQBB 2F1WA 2NZ0B 2XXNA 3OGKA 1D0JA 4JJQA 3LBZA 5FTAA 4YY8A 2P1QA 1LB4A 1CZZA 4GHUA 4N9F5 4JTAB 4ZGCA 2FNJC 1A68A 2F1XA 5JH5B 4APFA 1T1DA 4W9HH 3LUTB 1S1GA 4JTCB 3IVVA 4W9GB 5E1TA 4U77A 1D00A 3HQIA 1QDWA 4M4EA 4K8UA 4W9HB 3HTMA 5DADA 1LB5A 3C6PA 1ZMSA 3ZUNB 4BKSB 2AN6A 2R9RB 3ZTCB 4B9KB 3HU6A 5BXDA 2C9WC 4JGHC 3OGMA 3ZRCB 1FLLA 3HSVA 3V7DA 2E32B 2OVRA 1NN7A 2IF5A 2GKWA 2IHCA 2P1NA 3HVEB 4GWNA 1HV2A 1FQVB 2A25A 2PPIA 5BXBA 3ZKJB 2A79B 3DCGB 4W9KB 3B84A 4GJHA 1R2BA 3OHUA 4BKTB 5H7GA 4BGCA 4CXIA 4EOZA 2F1ZA 5DAFA 2Z8HA 4CP3A 3MQRA 4CA1A 4I7DA 4AP2A 1CA9A 3C6NA 3MKSA 3IVQA 4I7BA 3KVTA 3IVBA 4W9FB 3ZJBA 2CR2A 4AJYC 3FKCA 4CXTA 1R28A 3LNMB 4JTDB 1P22B 4W9IB 1QDVA 4O1VA 4B95B 2P1OA 4B9KE 5HZGC 1NEXA 3DRXA 3M5BA 5LLIB 2MA9C 3DRYA 4W9DB 1EXBE 4AWJB 3M4TA 3ZTDB 2FOOA 1EOEA 3L2OA 1LB6A 1LDKD 4WQOC 4GWMA 2P1PA 3WSOB 1LM8C 1K2FA 1L0AA 3I3NA 3M52A 1D0AA 4CRHA 4W9EB 4U2MA 5BO4C 1FS2B 4W9CB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1D01 A;  1KZZ A;  5H9M A;  1CA4 A;  4I6J C;  5HYW B;  2OVQ A;  4I7C A;  2IZV C;  4UIJ A;  1YZE A;  4CXJ A;  2P1M A;  5IBK A;  5EUP A;  2FOJ A;  3OHV A;  3E4U A;  1EOF A;  3DRZ A;  4W9L B;  3HQM A;  1DSX A;  2JZ3 C;  4HXI A;  3BIM A;  2OVP A;  2YY9 A;  2E31 B;  1RF3 A;  1CS3 A;  3HVE A;  5H7H A;  2ASS A;  1BUO A;  3MQS C;  4U2N A;  4C9Z A;  4UYI A;  2AST A;  1EOD A;  3C6O A;  5A15 A;  1FS1 B;  2I2R A;  1F3V B;  1YY6 A;  2FOP A;  1QSC A;  1FLK A;  2F1Y A;  2VKP A;  3HQL A;  4YSI A;  1VCB B;  2VPK A;  4W9J B;  3ZNG B;  1R29 A;  3HQH A;  2Q81 A;  4X3G A;  3M8V A;  4Z8M A;  3ZRF B;  5A6R A;  5BXH A;  2NN2 A;  3GA1 A;  1CZY A;  4J8Z A;  3OGL A;  4ZOU A;  4KG9 A;  1LQB B;  2F1W A;  2NZ0 B;  2XXN A;  3OGK A;  1D0J A;  4JJQ A;  3LBZ A;  5FTA A;  2P1Q A;  1LB4 A;  1CZZ A;  4GHU A;  4N9F 5;  4JTA B;  2FNJ C;  1A68 A;  2F1X A;  5JH5 B;  4APF A;  1T1D A;  4W9H H;  3LUT B;  1S1G A;  4JTC B;  3IVV A;  4W9G B;  5E1T A;  4U77 A;  1D00 A;  3HQI A;  1QDW A;  4M4E A;  4K8U A;  4W9H B;  3HTM A;  5DAD A;  1LB5 A;  3C6P A;  1ZMS A;  3ZUN B;  4BKS B;  2AN6 A;  2R9R B;  3ZTC B;  4B9K B;  3HU6 A;  5BXD A;  2C9W C;  4JGH C;  3OGM A;  3ZRC B;  1FLL A;  3HSV A;  3V7D A;  2E32 B;  2OVR A;  1NN7 A;  2IF5 A;  2GKW A;  2IHC A;  2P1N A;  3HVE B;  4GWN A;  1HV2 A;  1FQV B;  2A25 A;  2PPI A;  5BXB A;  3ZKJ B;  2A79 B;  3DCG B;  4W9K B;  3B84 A;  4GJH A;  1R2B A;  3OHU A;  4BKT B;  5H7G A;  4BGC A;  4CXI A;  4EOZ A;  2F1Z A;  5DAF A;  2Z8H A;  4CP3 A;  3MQR A;  4CA1 A;  4I7D A;  4AP2 A;  1CA9 A;  3C6N A;  3MKS A;  3IVQ A;  4I7B A;  3KVT A;  3IVB A;  4W9F B;  3ZJB A;  2CR2 A;  4AJY C;  3FKC A;  4CXT A;  1R28 A;  3LNM B;  4JTD B;  1P22 B;  4W9I B;  1QDV A;  4O1V A;  4B95 B;  2P1O A;  4B9K E;  5HZG C;  1NEX A;  3M5B A;  5LLI B;  2MA9 C;  4W9D B;  1EXB E;  4AWJ B;  3M4T A;  3ZTD B;  2FOO A;  1EOE A;  3L2O A;  1LB6 A;  1LDK D;  4WQO C;  4GWM A;  2P1P A;  3WSO B;  1LM8 C;  1K2F A;  1L0A A;  3I3N A;  3M52 A;  1D0A A;  4CRH A;  4W9E B;  4U2M A;  5BO4 C;  1FS2 B;  4W9C B; 
#chains in the Genus database with same CATH topology
 1D01 A;  1KZZ A;  5H9M A;  1CA4 A;  4I6J C;  5HYW B;  2OVQ A;  4I7C A;  2IZV C;  4UIJ A;  1YZE A;  4CXJ A;  2P1M A;  5IBK A;  5EUP A;  2FOJ A;  3OHV A;  3E4U A;  1EOF A;  3DRZ A;  4W9L B;  3HQM A;  1DSX A;  2JZ3 C;  4HXI A;  3BIM A;  2OVP A;  2YY9 A;  2E31 B;  1RF3 A;  1CS3 A;  3HVE A;  5H7H A;  2ASS A;  1BUO A;  3MQS C;  4U2N A;  4C9Z A;  4UYI A;  2AST A;  1EOD A;  3C6O A;  5A15 A;  1FS1 B;  2I2R A;  1F3V B;  1YY6 A;  2FOP A;  1QSC A;  1FLK A;  2F1Y A;  2VKP A;  3HQL A;  4YSI A;  1VCB B;  2VPK A;  4W9J B;  3ZNG B;  1R29 A;  3HQH A;  2Q81 A;  4X3G A;  3M8V A;  4Z8M A;  3ZRF B;  5A6R A;  5BXH A;  2NN2 A;  3GA1 A;  1CZY A;  4J8Z A;  3OGL A;  4ZOU A;  4KG9 A;  1LQB B;  2F1W A;  2NZ0 B;  2XXN A;  3OGK A;  1D0J A;  4JJQ A;  3LBZ A;  5FTA A;  4YY8 A;  2P1Q A;  1LB4 A;  1CZZ A;  4GHU A;  4N9F 5;  4JTA B;  4ZGC A;  2FNJ C;  1A68 A;  2F1X A;  5JH5 B;  4APF A;  1T1D A;  4W9H H;  3LUT B;  1S1G A;  4JTC B;  3IVV A;  4W9G B;  5E1T A;  4U77 A;  1D00 A;  3HQI A;  1QDW A;  4M4E A;  4K8U A;  4W9H B;  3HTM A;  5DAD A;  1LB5 A;  3C6P A;  1ZMS A;  3ZUN B;  4BKS B;  2AN6 A;  2R9R B;  3ZTC B;  4B9K B;  3HU6 A;  5BXD A;  2C9W C;  4JGH C;  3OGM A;  3ZRC B;  1FLL A;  3HSV A;  3V7D A;  2E32 B;  2OVR A;  1NN7 A;  2IF5 A;  2GKW A;  2IHC A;  2P1N A;  3HVE B;  4GWN A;  1HV2 A;  1FQV B;  2A25 A;  2PPI A;  5BXB A;  3ZKJ B;  2A79 B;  3DCG B;  4W9K B;  3B84 A;  4GJH A;  1R2B A;  3OHU A;  4BKT B;  5H7G A;  4BGC A;  4CXI A;  4EOZ A;  2F1Z A;  5DAF A;  2Z8H A;  4CP3 A;  3MQR A;  4CA1 A;  4I7D A;  4AP2 A;  1CA9 A;  3C6N A;  3MKS A;  3IVQ A;  4I7B A;  3KVT A;  3IVB A;  4W9F B;  3ZJB A;  2CR2 A;  4AJY C;  3FKC A;  4CXT A;  1R28 A;  3LNM B;  4JTD B;  1P22 B;  4W9I B;  1QDV A;  4O1V A;  4B95 B;  2P1O A;  4B9K E;  5HZG C;  1NEX A;  3DRX A;  3M5B A;  5LLI B;  2MA9 C;  3DRY A;  4W9D B;  1EXB E;  4AWJ B;  3M4T A;  3ZTD B;  2FOO A;  1EOE A;  3L2O A;  1LB6 A;  1LDK D;  4WQO C;  4GWM A;  2P1P A;  3WSO B;  1LM8 C;  1K2F A;  1L0A A;  3I3N A;  3M52 A;  1D0A A;  4CRH A;  4W9E B;  4U2M A;  5BO4 C;  1FS2 B;  4W9C B; 
#chains in the Genus database with same CATH homology
 1D01 A;  1KZZ A;  5H9M A;  1CA4 A;  4I6J C;  5HYW B;  2OVQ A;  4I7C A;  2IZV C;  4UIJ A;  1YZE A;  4CXJ A;  2P1M A;  5IBK A;  5EUP A;  2FOJ A;  3OHV A;  3E4U A;  1EOF A;  3DRZ A;  4W9L B;  3HQM A;  1DSX A;  2JZ3 C;  4HXI A;  3BIM A;  2OVP A;  2YY9 A;  2E31 B;  1RF3 A;  1CS3 A;  3HVE A;  5H7H A;  2ASS A;  1BUO A;  3MQS C;  4U2N A;  4C9Z A;  4UYI A;  2AST A;  1EOD A;  3C6O A;  5A15 A;  1FS1 B;  2I2R A;  1F3V B;  1YY6 A;  2FOP A;  1QSC A;  1FLK A;  2F1Y A;  2VKP A;  3HQL A;  4YSI A;  1VCB B;  2VPK A;  4W9J B;  3ZNG B;  1R29 A;  3HQH A;  2Q81 A;  4X3G A;  3M8V A;  4Z8M A;  3ZRF B;  5A6R A;  5BXH A;  2NN2 A;  3GA1 A;  1CZY A;  4J8Z A;  3OGL A;  4ZOU A;  4KG9 A;  1LQB B;  2F1W A;  2NZ0 B;  2XXN A;  3OGK A;  1D0J A;  4JJQ A;  3LBZ A;  5FTA A;  4YY8 A;  2P1Q A;  1LB4 A;  1CZZ A;  4GHU A;  4N9F 5;  4JTA B;  4ZGC A;  2FNJ C;  1A68 A;  2F1X A;  5JH5 B;  4APF A;  1T1D A;  4W9H H;  3LUT B;  1S1G A;  4JTC B;  3IVV A;  4W9G B;  5E1T A;  4U77 A;  1D00 A;  3HQI A;  1QDW A;  4M4E A;  4K8U A;  4W9H B;  3HTM A;  5DAD A;  1LB5 A;  3C6P A;  1ZMS A;  3ZUN B;  4BKS B;  2AN6 A;  2R9R B;  3ZTC B;  4B9K B;  3HU6 A;  5BXD A;  2C9W C;  4JGH C;  3OGM A;  3ZRC B;  1FLL A;  3HSV A;  3V7D A;  2E32 B;  2OVR A;  1NN7 A;  2IF5 A;  2GKW A;  2IHC A;  2P1N A;  3HVE B;  4GWN A;  1HV2 A;  1FQV B;  2A25 A;  2PPI A;  5BXB A;  3ZKJ B;  2A79 B;  3DCG B;  4W9K B;  3B84 A;  4GJH A;  1R2B A;  3OHU A;  4BKT B;  5H7G A;  4BGC A;  4CXI A;  4EOZ A;  2F1Z A;  5DAF A;  2Z8H A;  4CP3 A;  3MQR A;  4CA1 A;  4I7D A;  4AP2 A;  1CA9 A;  3C6N A;  3MKS A;  3IVQ A;  4I7B A;  3KVT A;  3IVB A;  4W9F B;  3ZJB A;  2CR2 A;  4AJY C;  3FKC A;  4CXT A;  1R28 A;  3LNM B;  4JTD B;  1P22 B;  4W9I B;  1QDV A;  4O1V A;  4B95 B;  2P1O A;  4B9K E;  5HZG C;  1NEX A;  3DRX A;  3M5B A;  5LLI B;  2MA9 C;  3DRY A;  4W9D B;  1EXB E;  4AWJ B;  3M4T A;  3ZTD B;  2FOO A;  1EOE A;  3L2O A;  1LB6 A;  1LDK D;  4WQO C;  4GWM A;  2P1P A;  3WSO B;  1LM8 C;  1K2F A;  1L0A A;  3I3N A;  3M52 A;  1D0A A;  4CRH A;  4W9E B;  4U2M A;  5BO4 C;  1FS2 B;  4W9C B; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...