3HQIA

Structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
304
structure length
294
Chain Sequence
GSKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSNDKLKWCLRVNPKGLDSKDYLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
pubmed doi rcsb
molecule tags Protein binding, ligase
source organism Homo sapiens
molecule keywords Speckle-type POZ protein
total genus 67
structure length 294
sequence length 304
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00651 BTB BTB/POZ domain
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 3hqiA01
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 3hqiA02
5BXHA 4HXIA 3IVVA 2IZVC 3LBZA 5DAFA 2CR2A 1DSXA 1FQVB 1LM8C 4I7BA 2A79B 3I3NA 5EUPA 1R28A 3ZNGB 3FKCA 4EOZA 4M4EA 1L0AA 5H7GA 4GWMA 1NEXA 1R2BA 2I2RA 4AP2A 4CXTA 2AN6A 1D00A 4W9LB 1HV2A 2IHCA 4U2MA 3B84A 4N9F5 4U77A 3LNMB 1F3VB 2OVPA 4W9GB 2VPKA 4GJHA 1VCBB 2OVQA 1QDWA 3DCGB 4JTAB 5DADA 4W9HH 3HVEA 3HVEB 5BXDA 5H9MA 4BKTB 2NZ0B 2NN2A 4APFA 1RF3A 5H7HA 1CZZA 1LB5A 3C6PA 2FNJC 1ZMSA 4AWJB 4CP3A 1YZEA 4CXIA 4W9IB 4C9ZA 4GWNA 4CRHA 3HQHA 1CA4A 2E32B 3OHVA 4B9KE 3GA1A 5A6RA 4W9DB 4CXJA 4W9JB 3MKSA 4AJYC 3OGLA 5JH5B 2IF5A 1LDKD 2P1PA 3OGMA 1NN7A 2FOOA 2OVRA 3LUTB 3ZRCB 5A15A 1FS2B 2VKPA 2YY9A 5BXBA 1D0AA 1QSCA 1T1DA 4W9HB 3MQSC 4J8ZA 3IVBA 3ZRFB 3OGKA 3C6OA 1FLLA 2E31B 2F1ZA 3DRZA 4JTDB 2XXNA 2MA9C 2P1NA 2F1YA 1EOEA 4JGHC 1CS3A 1D0JA 3WSOB 5IBKA 1S1GA 5BO4C 3C6NA 1YY6A 4B95B 2F1XA 3V7DA 2Q81A 3ZTDB 1LQBB 1QDVA 2C9WC 3M8VA 4U2NA 4W9FB 4JJQA 1K2FA 4O1VA 3HQLA 1CA9A 5E1TA 1EODA 3HTMA 2JZ3C 1R29A 2FOPA 3M52A 3HQIA 2R9RB 2PPIA 3E4UA 3HSVA 4B9KB 1LB4A 1P22B 2ASSA 1KZZA 2A25A 4GHUA 4I7CA 3BIMA 4UIJA 4CA1A 4BKSB 2GKWA 3OHUA 1LB6A 4W9EB 2ASTA 4W9CB 3IVQA 3ZJBA 4BGCA 4I7DA 4YSIA 4WQOC 3L2OA 5HZGC 3ZUNB 4I6JC 4K8UA 1FS1B 2P1MA 2P1QA 2Z8HA 1EOFA 1D01A 3MQRA 4X3GA 1EXBE 3KVTA 4UYIA 3ZKJB 5HYWB 3HU6A 1CZYA 2F1WA 1BUOA 2P1OA 4W9KB 4Z8MA 3M4TA 3ZTCB 5LLIB 1FLKA 1A68A 4JTCB 4KG9A 3M5BA 2FOJA 3HQMA 4ZOUA 5FTAA
chains in the Genus database with same CATH superfamily
5BXHA 4HXIA 3IVVA 2IZVC 3LBZA 5DAFA 2CR2A 1DSXA 1FQVB 1LM8C 4I7BA 2A79B 3I3NA 5EUPA 1R28A 3ZNGB 3FKCA 4EOZA 4M4EA 1L0AA 5H7GA 4GWMA 1NEXA 1R2BA 2I2RA 4AP2A 4CXTA 2AN6A 1D00A 4W9LB 1HV2A 2IHCA 4U2MA 3B84A 4N9F5 4U77A 3LNMB 1F3VB 2OVPA 4W9GB 2VPKA 4GJHA 1VCBB 2OVQA 1QDWA 3DCGB 4JTAB 5DADA 3DRYA 4W9HH 3HVEA 3HVEB 5BXDA 5H9MA 4BKTB 2NZ0B 2NN2A 4APFA 1RF3A 5H7HA 1CZZA 1LB5A 3C6PA 2FNJC 1ZMSA 4AWJB 4CP3A 1YZEA 4CXIA 4W9IB 4C9ZA 4GWNA 4CRHA 3HQHA 1CA4A 2E32B 3OHVA 4B9KE 3GA1A 5A6RA 4W9DB 4CXJA 4W9JB 3MKSA 4AJYC 4ZGCA 3OGLA 5JH5B 2IF5A 1LDKD 2P1PA 3OGMA 1NN7A 2FOOA 2OVRA 3LUTB 3ZRCB 5A15A 1FS2B 2VKPA 2YY9A 5BXBA 1D0AA 1QSCA 1T1DA 4W9HB 3MQSC 4J8ZA 3IVBA 3ZRFB 3OGKA 3C6OA 1FLLA 2E31B 4YY8A 2F1ZA 3DRZA 4JTDB 2XXNA 2MA9C 2P1NA 2F1YA 1EOEA 4JGHC 1CS3A 1D0JA 3WSOB 5IBKA 1S1GA 5BO4C 3C6NA 1YY6A 4B95B 2F1XA 3V7DA 2Q81A 3ZTDB 1LQBB 1QDVA 2C9WC 3M8VA 4U2NA 4W9FB 4JJQA 1K2FA 4O1VA 3HQLA 1CA9A 5E1TA 1EODA 3HTMA 2JZ3C 1R29A 3DRXA 2FOPA 3M52A 3HQIA 2R9RB 2PPIA 3E4UA 3HSVA 4B9KB 1LB4A 1P22B 2ASSA 1KZZA 2A25A 4GHUA 4I7CA 3BIMA 4UIJA 4CA1A 4BKSB 2GKWA 3OHUA 1LB6A 4W9EB 2ASTA 4W9CB 3IVQA 3ZJBA 4BGCA 4I7DA 4YSIA 4WQOC 3L2OA 5HZGC 3ZUNB 4I6JC 4K8UA 1FS1B 2P1MA 2P1QA 2Z8HA 1EOFA 1D01A 3MQRA 4X3GA 1EXBE 3KVTA 4UYIA 3ZKJB 5HYWB 3HU6A 1CZYA 2F1WA 1BUOA 2P1OA 4W9KB 4Z8MA 3M4TA 3ZTCB 5LLIB 1FLKA 1A68A 4JTCB 4KG9A 3M5BA 2FOJA 3HQMA 4ZOUA 5FTAA
chains in the Genus database with same CATH topology
5BXHA 4HXIA 3IVVA 2IZVC 3LBZA 5DAFA 2CR2A 1DSXA 1FQVB 1LM8C 4I7BA 2A79B 3I3NA 5EUPA 1R28A 3ZNGB 3FKCA 4EOZA 4M4EA 1L0AA 5H7GA 4GWMA 1NEXA 1R2BA 2I2RA 4AP2A 4CXTA 2AN6A 1D00A 4W9LB 1HV2A 2IHCA 4U2MA 3B84A 4N9F5 4U77A 3LNMB 1F3VB 2OVPA 4W9GB 2VPKA 4GJHA 1VCBB 2OVQA 1QDWA 3DCGB 4JTAB 5DADA 3DRYA 4W9HH 3HVEA 3HVEB 5BXDA 5H9MA 4BKTB 2NZ0B 2NN2A 4APFA 1RF3A 5H7HA 1CZZA 1LB5A 3C6PA 2FNJC 1ZMSA 4AWJB 4CP3A 1YZEA 4CXIA 4W9IB 4C9ZA 4GWNA 4CRHA 3HQHA 1CA4A 2E32B 3OHVA 4B9KE 3GA1A 5A6RA 4W9DB 4CXJA 4W9JB 3MKSA 4AJYC 4ZGCA 3OGLA 5JH5B 2IF5A 1LDKD 2P1PA 3OGMA 1NN7A 2FOOA 2OVRA 3LUTB 3ZRCB 5A15A 1FS2B 2VKPA 2YY9A 5BXBA 1D0AA 1QSCA 1T1DA 4W9HB 3MQSC 4J8ZA 3IVBA 3ZRFB 3OGKA 3C6OA 1FLLA 2E31B 4YY8A 2F1ZA 3DRZA 4JTDB 2XXNA 2MA9C 2P1NA 2F1YA 1EOEA 4JGHC 1CS3A 1D0JA 3WSOB 5IBKA 1S1GA 5BO4C 3C6NA 1YY6A 4B95B 2F1XA 3V7DA 2Q81A 3ZTDB 1LQBB 1QDVA 2C9WC 3M8VA 4U2NA 4W9FB 4JJQA 1K2FA 4O1VA 3HQLA 1CA9A 5E1TA 1EODA 3HTMA 2JZ3C 1R29A 3DRXA 2FOPA 3M52A 3HQIA 2R9RB 2PPIA 3E4UA 3HSVA 4B9KB 1LB4A 1P22B 2ASSA 1KZZA 2A25A 4GHUA 4I7CA 3BIMA 4UIJA 4CA1A 4BKSB 2GKWA 3OHUA 1LB6A 4W9EB 2ASTA 4W9CB 3IVQA 3ZJBA 4BGCA 4I7DA 4YSIA 4WQOC 3L2OA 5HZGC 3ZUNB 4I6JC 4K8UA 1FS1B 2P1MA 2P1QA 2Z8HA 1EOFA 1D01A 3MQRA 4X3GA 1EXBE 3KVTA 4UYIA 3ZKJB 5HYWB 3HU6A 1CZYA 2F1WA 1BUOA 2P1OA 4W9KB 4Z8MA 3M4TA 3ZTCB 5LLIB 1FLKA 1A68A 4JTCB 4KG9A 3M5BA 2FOJA 3HQMA 4ZOUA 5FTAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BXH A;  4HXI A;  3IVV A;  2IZV C;  3LBZ A;  5DAF A;  2CR2 A;  1DSX A;  1FQV B;  1LM8 C;  4I7B A;  2A79 B;  3I3N A;  5EUP A;  1R28 A;  3ZNG B;  3FKC A;  4EOZ A;  4M4E A;  1L0A A;  5H7G A;  4GWM A;  1NEX A;  1R2B A;  2I2R A;  4AP2 A;  4CXT A;  2AN6 A;  1D00 A;  4W9L B;  1HV2 A;  2IHC A;  4U2M A;  3B84 A;  4N9F 5;  4U77 A;  3LNM B;  1F3V B;  2OVP A;  4W9G B;  2VPK A;  4GJH A;  1VCB B;  2OVQ A;  1QDW A;  3DCG B;  4JTA B;  5DAD A;  4W9H H;  3HVE A;  3HVE B;  5BXD A;  5H9M A;  4BKT B;  2NZ0 B;  2NN2 A;  4APF A;  1RF3 A;  5H7H A;  1CZZ A;  1LB5 A;  3C6P A;  2FNJ C;  1ZMS A;  4AWJ B;  4CP3 A;  1YZE A;  4CXI A;  4W9I B;  4C9Z A;  4GWN A;  4CRH A;  3HQH A;  1CA4 A;  2E32 B;  3OHV A;  4B9K E;  3GA1 A;  5A6R A;  4W9D B;  4CXJ A;  4W9J B;  3MKS A;  4AJY C;  3OGL A;  5JH5 B;  2IF5 A;  1LDK D;  2P1P A;  3OGM A;  1NN7 A;  2FOO A;  2OVR A;  3LUT B;  3ZRC B;  5A15 A;  1FS2 B;  2VKP A;  2YY9 A;  5BXB A;  1D0A A;  1QSC A;  1T1D A;  4W9H B;  3MQS C;  4J8Z A;  3IVB A;  3ZRF B;  3OGK A;  3C6O A;  1FLL A;  2E31 B;  2F1Z A;  3DRZ A;  4JTD B;  2XXN A;  2MA9 C;  2P1N A;  2F1Y A;  1EOE A;  4JGH C;  1CS3 A;  1D0J A;  3WSO B;  5IBK A;  1S1G A;  5BO4 C;  3C6N A;  1YY6 A;  4B95 B;  2F1X A;  3V7D A;  2Q81 A;  3ZTD B;  1LQB B;  1QDV A;  2C9W C;  3M8V A;  4U2N A;  4W9F B;  4JJQ A;  1K2F A;  4O1V A;  3HQL A;  1CA9 A;  5E1T A;  1EOD A;  3HTM A;  2JZ3 C;  1R29 A;  2FOP A;  3M52 A;  3HQI A;  2R9R B;  2PPI A;  3E4U A;  3HSV A;  4B9K B;  1LB4 A;  1P22 B;  2ASS A;  1KZZ A;  2A25 A;  4GHU A;  4I7C A;  3BIM A;  4UIJ A;  4CA1 A;  4BKS B;  2GKW A;  3OHU A;  1LB6 A;  4W9E B;  2AST A;  4W9C B;  3IVQ A;  3ZJB A;  4BGC A;  4I7D A;  4YSI A;  4WQO C;  3L2O A;  5HZG C;  3ZUN B;  4I6J C;  4K8U A;  1FS1 B;  2P1M A;  2P1Q A;  2Z8H A;  1EOF A;  1D01 A;  3MQR A;  4X3G A;  1EXB E;  3KVT A;  4UYI A;  3ZKJ B;  5HYW B;  3HU6 A;  1CZY A;  2F1W A;  1BUO A;  2P1O A;  4W9K B;  4Z8M A;  3M4T A;  3ZTC B;  5LLI B;  1FLK A;  1A68 A;  4JTC B;  4KG9 A;  3M5B A;  2FOJ A;  3HQM A;  4ZOU A;  5FTA A; 
#chains in the Genus database with same CATH topology
 5BXH A;  4HXI A;  3IVV A;  2IZV C;  3LBZ A;  5DAF A;  2CR2 A;  1DSX A;  1FQV B;  1LM8 C;  4I7B A;  2A79 B;  3I3N A;  5EUP A;  1R28 A;  3ZNG B;  3FKC A;  4EOZ A;  4M4E A;  1L0A A;  5H7G A;  4GWM A;  1NEX A;  1R2B A;  2I2R A;  4AP2 A;  4CXT A;  2AN6 A;  1D00 A;  4W9L B;  1HV2 A;  2IHC A;  4U2M A;  3B84 A;  4N9F 5;  4U77 A;  3LNM B;  1F3V B;  2OVP A;  4W9G B;  2VPK A;  4GJH A;  1VCB B;  2OVQ A;  1QDW A;  3DCG B;  4JTA B;  5DAD A;  3DRY A;  4W9H H;  3HVE A;  3HVE B;  5BXD A;  5H9M A;  4BKT B;  2NZ0 B;  2NN2 A;  4APF A;  1RF3 A;  5H7H A;  1CZZ A;  1LB5 A;  3C6P A;  2FNJ C;  1ZMS A;  4AWJ B;  4CP3 A;  1YZE A;  4CXI A;  4W9I B;  4C9Z A;  4GWN A;  4CRH A;  3HQH A;  1CA4 A;  2E32 B;  3OHV A;  4B9K E;  3GA1 A;  5A6R A;  4W9D B;  4CXJ A;  4W9J B;  3MKS A;  4AJY C;  4ZGC A;  3OGL A;  5JH5 B;  2IF5 A;  1LDK D;  2P1P A;  3OGM A;  1NN7 A;  2FOO A;  2OVR A;  3LUT B;  3ZRC B;  5A15 A;  1FS2 B;  2VKP A;  2YY9 A;  5BXB A;  1D0A A;  1QSC A;  1T1D A;  4W9H B;  3MQS C;  4J8Z A;  3IVB A;  3ZRF B;  3OGK A;  3C6O A;  1FLL A;  2E31 B;  4YY8 A;  2F1Z A;  3DRZ A;  4JTD B;  2XXN A;  2MA9 C;  2P1N A;  2F1Y A;  1EOE A;  4JGH C;  1CS3 A;  1D0J A;  3WSO B;  5IBK A;  1S1G A;  5BO4 C;  3C6N A;  1YY6 A;  4B95 B;  2F1X A;  3V7D A;  2Q81 A;  3ZTD B;  1LQB B;  1QDV A;  2C9W C;  3M8V A;  4U2N A;  4W9F B;  4JJQ A;  1K2F A;  4O1V A;  3HQL A;  1CA9 A;  5E1T A;  1EOD A;  3HTM A;  2JZ3 C;  1R29 A;  3DRX A;  2FOP A;  3M52 A;  3HQI A;  2R9R B;  2PPI A;  3E4U A;  3HSV A;  4B9K B;  1LB4 A;  1P22 B;  2ASS A;  1KZZ A;  2A25 A;  4GHU A;  4I7C A;  3BIM A;  4UIJ A;  4CA1 A;  4BKS B;  2GKW A;  3OHU A;  1LB6 A;  4W9E B;  2AST A;  4W9C B;  3IVQ A;  3ZJB A;  4BGC A;  4I7D A;  4YSI A;  4WQO C;  3L2O A;  5HZG C;  3ZUN B;  4I6J C;  4K8U A;  1FS1 B;  2P1M A;  2P1Q A;  2Z8H A;  1EOF A;  1D01 A;  3MQR A;  4X3G A;  1EXB E;  3KVT A;  4UYI A;  3ZKJ B;  5HYW B;  3HU6 A;  1CZY A;  2F1W A;  1BUO A;  2P1O A;  4W9K B;  4Z8M A;  3M4T A;  3ZTC B;  5LLI B;  1FLK A;  1A68 A;  4JTC B;  4KG9 A;  3M5B A;  2FOJ A;  3HQM A;  4ZOU A;  5FTA A; 
#chains in the Genus database with same CATH homology
 5BXH A;  4HXI A;  3IVV A;  2IZV C;  3LBZ A;  5DAF A;  2CR2 A;  1DSX A;  1FQV B;  1LM8 C;  4I7B A;  2A79 B;  3I3N A;  5EUP A;  1R28 A;  3ZNG B;  3FKC A;  4EOZ A;  4M4E A;  1L0A A;  5H7G A;  4GWM A;  1NEX A;  1R2B A;  2I2R A;  4AP2 A;  4CXT A;  2AN6 A;  1D00 A;  4W9L B;  1HV2 A;  2IHC A;  4U2M A;  3B84 A;  4N9F 5;  4U77 A;  3LNM B;  1F3V B;  2OVP A;  4W9G B;  2VPK A;  4GJH A;  1VCB B;  2OVQ A;  1QDW A;  3DCG B;  4JTA B;  5DAD A;  3DRY A;  4W9H H;  3HVE A;  3HVE B;  5BXD A;  5H9M A;  4BKT B;  2NZ0 B;  2NN2 A;  4APF A;  1RF3 A;  5H7H A;  1CZZ A;  1LB5 A;  3C6P A;  2FNJ C;  1ZMS A;  4AWJ B;  4CP3 A;  1YZE A;  4CXI A;  4W9I B;  4C9Z A;  4GWN A;  4CRH A;  3HQH A;  1CA4 A;  2E32 B;  3OHV A;  4B9K E;  3GA1 A;  5A6R A;  4W9D B;  4CXJ A;  4W9J B;  3MKS A;  4AJY C;  4ZGC A;  3OGL A;  5JH5 B;  2IF5 A;  1LDK D;  2P1P A;  3OGM A;  1NN7 A;  2FOO A;  2OVR A;  3LUT B;  3ZRC B;  5A15 A;  1FS2 B;  2VKP A;  2YY9 A;  5BXB A;  1D0A A;  1QSC A;  1T1D A;  4W9H B;  3MQS C;  4J8Z A;  3IVB A;  3ZRF B;  3OGK A;  3C6O A;  1FLL A;  2E31 B;  4YY8 A;  2F1Z A;  3DRZ A;  4JTD B;  2XXN A;  2MA9 C;  2P1N A;  2F1Y A;  1EOE A;  4JGH C;  1CS3 A;  1D0J A;  3WSO B;  5IBK A;  1S1G A;  5BO4 C;  3C6N A;  1YY6 A;  4B95 B;  2F1X A;  3V7D A;  2Q81 A;  3ZTD B;  1LQB B;  1QDV A;  2C9W C;  3M8V A;  4U2N A;  4W9F B;  4JJQ A;  1K2F A;  4O1V A;  3HQL A;  1CA9 A;  5E1T A;  1EOD A;  3HTM A;  2JZ3 C;  1R29 A;  3DRX A;  2FOP A;  3M52 A;  3HQI A;  2R9R B;  2PPI A;  3E4U A;  3HSV A;  4B9K B;  1LB4 A;  1P22 B;  2ASS A;  1KZZ A;  2A25 A;  4GHU A;  4I7C A;  3BIM A;  4UIJ A;  4CA1 A;  4BKS B;  2GKW A;  3OHU A;  1LB6 A;  4W9E B;  2AST A;  4W9C B;  3IVQ A;  3ZJB A;  4BGC A;  4I7D A;  4YSI A;  4WQO C;  3L2O A;  5HZG C;  3ZUN B;  4I6J C;  4K8U A;  1FS1 B;  2P1M A;  2P1Q A;  2Z8H A;  1EOF A;  1D01 A;  3MQR A;  4X3G A;  1EXB E;  3KVT A;  4UYI A;  3ZKJ B;  5HYW B;  3HU6 A;  1CZY A;  2F1W A;  1BUO A;  2P1O A;  4W9K B;  4Z8M A;  3M4T A;  3ZTC B;  5LLI B;  1FLK A;  1A68 A;  4JTC B;  4KG9 A;  3M5B A;  2FOJ A;  3HQM A;  4ZOU A;  5FTA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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