3HU6A

Structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
303
structure length
284
Chain Sequence
SKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSKLKWCLRVNPKGLDSKDYLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSQTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
pubmed doi rcsb
molecule tags Protein binding, ligase
source organism Homo sapiens
molecule keywords Speckle-type POZ protein
total genus 64
structure length 284
sequence length 303
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00651 BTB BTB/POZ domain
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 3hu6A01
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 3hu6A02
2F1XA 4HXIA 5BO4C 3M5BA 1D0JA 3BIMA 2ASSA 3ZTDB 2GKWA 4CRHA 5E1TA 1F3VB 3V7DA 3HVEA 1QSCA 2FOPA 2P1QA 1D00A 2FOOA 4M4EA 2NN2A 5EUPA 1NEXA 4YSIA 1CZZA 4UYIA 5H7GA 3ZUNB 1FLLA 1R2BA 2P1NA 2F1YA 4BKTB 4U77A 2YY9A 2MA9C 4CXTA 3HQIA 2P1PA 1KZZA 1LM8C 3ZNGB 4U2NA 3ZJBA 4AJYC 4W9LB 4K8UA 4APFA 2JZ3C 2F1WA 4W9JB 3C6OA 4KG9A 4W9IB 1CA9A 2VPKA 2Q81A 4W9GB 5H9MA 1NN7A 3HU6A 4GWMA 3HTMA 4W9KB 2IHCA 2PPIA 3M52A 3LBZA 3ZKJB 4Z8MA 1D0AA 2CR2A 2I2RA 3LUTB 5DADA 3ZRCB 4J8ZA 5LLIB 3MQRA 3WSOB 4X3GA 3HQMA 3HSVA 3MKSA 3FKCA 5BXBA 1EXBE 3I3NA 1D01A 4I7CA 4N9F5 4AP2A 1S1GA 1RF3A 2A25A 2E32B 3OGMA 3OHUA 2R9RB 1DSXA 4BKSB 4GJHA 5HYWB 4JTCB 1QDWA 1EOEA 3IVVA 2FOJA 1K2FA 4WQOC 4W9HB 2C9WC 5A6RA 3C6PA 4CXIA 4CA1A 1HV2A 2AN6A 3IVBA 5A15A 2IZVC 1BUOA 3HQLA 1ZMSA 2NZ0B 3L2OA 1FS1B 1A68A 2FNJC 3M4TA 4AWJB 1T1DA 2VKPA 4JTDB 4I6JC 2E31B 2Z8HA 4JGHC 4CXJA 3E4UA 4W9EB 5FTAA 5BXDA 3M8VA 5JH5B 4O1VA 1LDKD 4GWNA 4GHUA 4U2MA 1FLKA 1QDVA 1YY6A 4W9DB 2ASTA 3GA1A 5IBKA 2XXNA 3IVQA 4B9KE 1P22B 1LB6A 3ZRFB 1FQVB 2OVQA 3DCGB 5DAFA 4JJQA 3OGLA 3LNMB 4UIJA 5BXHA 1YZEA 3DRZA 1L0AA 5HZGC 1LB5A 1EOFA 1VCBB 4W9HH 4C9ZA 3KVTA 3OHVA 4B95B 5H7HA 2P1MA 4CP3A 3ZTCB 4B9KB 3B84A 4I7DA 2F1ZA 3HVEB 4W9FB 4ZOUA 3C6NA 1R29A 4I7BA 3HQHA 1EODA 1CA4A 2OVRA 4JTAB 1R28A 2P1OA 1FS2B 4BGCA 2IF5A 4W9CB 1CS3A 2A79B 3OGKA 1LQBB 2OVPA 1CZYA 1LB4A 4EOZA 3MQSC
chains in the Genus database with same CATH superfamily
2F1XA 4HXIA 5BO4C 3M5BA 1D0JA 3BIMA 2ASSA 3ZTDB 2GKWA 4CRHA 5E1TA 1F3VB 3V7DA 3HVEA 1QSCA 2FOPA 2P1QA 1D00A 2FOOA 4M4EA 2NN2A 5EUPA 1NEXA 4YSIA 1CZZA 4UYIA 5H7GA 3ZUNB 1FLLA 1R2BA 2P1NA 2F1YA 4BKTB 4U77A 2YY9A 2MA9C 4CXTA 3HQIA 2P1PA 1KZZA 1LM8C 3ZNGB 4U2NA 3ZJBA 4AJYC 4W9LB 4K8UA 4ZGCA 4APFA 2JZ3C 2F1WA 4W9JB 3C6OA 4KG9A 4W9IB 1CA9A 2VPKA 2Q81A 4W9GB 5H9MA 1NN7A 3HU6A 4GWMA 3DRYA 3HTMA 2IHCA 2PPIA 3M52A 4W9KB 3LBZA 3ZKJB 4Z8MA 1D0AA 2CR2A 2I2RA 3LUTB 5DADA 3ZRCB 4J8ZA 5LLIB 3MQRA 3WSOB 4X3GA 3HQMA 3HSVA 3MKSA 3FKCA 5BXBA 1EXBE 3I3NA 1D01A 4I7CA 4N9F5 4AP2A 1S1GA 1RF3A 2A25A 2E32B 3OGMA 3OHUA 2R9RB 1DSXA 4BKSB 4GJHA 5HYWB 4JTCB 1QDWA 1EOEA 3IVVA 2FOJA 1K2FA 4WQOC 4W9HB 2C9WC 3DRXA 5A6RA 3C6PA 4CXIA 4CA1A 1HV2A 2AN6A 3IVBA 5A15A 2IZVC 1BUOA 3HQLA 1ZMSA 2NZ0B 3L2OA 1FS1B 1A68A 2FNJC 3M4TA 4AWJB 1T1DA 2VKPA 4JTDB 4I6JC 2E31B 2Z8HA 4JGHC 4CXJA 3E4UA 4W9EB 5FTAA 5BXDA 3M8VA 5JH5B 4O1VA 1LDKD 4GWNA 4GHUA 4U2MA 1FLKA 1QDVA 1YY6A 4W9DB 2ASTA 3GA1A 5IBKA 2XXNA 3IVQA 4B9KE 1P22B 1LB6A 3ZRFB 1FQVB 2OVQA 3DCGB 5DAFA 4JJQA 3OGLA 3LNMB 4UIJA 5BXHA 1YZEA 3DRZA 1L0AA 5HZGC 1LB5A 1EOFA 1VCBB 4W9HH 4C9ZA 3KVTA 3OHVA 4YY8A 4B95B 5H7HA 2P1MA 4CP3A 3ZTCB 4B9KB 3B84A 4I7DA 2F1ZA 3HVEB 4W9FB 4ZOUA 3C6NA 1R29A 4I7BA 3HQHA 1EODA 1CA4A 2OVRA 4JTAB 1R28A 2P1OA 1FS2B 4BGCA 2IF5A 4W9CB 1CS3A 2A79B 3OGKA 1LQBB 2OVPA 1CZYA 1LB4A 4EOZA 3MQSC
chains in the Genus database with same CATH topology
2F1XA 4HXIA 5BO4C 3M5BA 1D0JA 3BIMA 2ASSA 3ZTDB 2GKWA 4CRHA 5E1TA 1F3VB 3V7DA 3HVEA 1QSCA 2FOPA 2P1QA 1D00A 2FOOA 4M4EA 2NN2A 5EUPA 1NEXA 4YSIA 1CZZA 4UYIA 5H7GA 3ZUNB 1FLLA 1R2BA 2P1NA 2F1YA 4BKTB 4U77A 2YY9A 2MA9C 4CXTA 3HQIA 2P1PA 1KZZA 1LM8C 3ZNGB 4U2NA 3ZJBA 4AJYC 4W9LB 4K8UA 4ZGCA 4APFA 2JZ3C 2F1WA 4W9JB 3C6OA 4KG9A 4W9IB 1CA9A 2VPKA 2Q81A 4W9GB 5H9MA 1NN7A 3HU6A 4GWMA 3DRYA 3HTMA 2IHCA 2PPIA 3M52A 4W9KB 3LBZA 3ZKJB 4Z8MA 1D0AA 2CR2A 2I2RA 3LUTB 5DADA 3ZRCB 4J8ZA 5LLIB 3MQRA 3WSOB 4X3GA 3HQMA 3HSVA 3MKSA 3FKCA 5BXBA 1EXBE 3I3NA 1D01A 4I7CA 4N9F5 4AP2A 1S1GA 1RF3A 2A25A 2E32B 3OGMA 3OHUA 2R9RB 1DSXA 4BKSB 4GJHA 5HYWB 4JTCB 1QDWA 1EOEA 3IVVA 2FOJA 1K2FA 4WQOC 4W9HB 2C9WC 3DRXA 5A6RA 3C6PA 4CXIA 4CA1A 1HV2A 2AN6A 3IVBA 5A15A 2IZVC 1BUOA 3HQLA 1ZMSA 2NZ0B 3L2OA 1FS1B 1A68A 2FNJC 3M4TA 4AWJB 1T1DA 2VKPA 4JTDB 4I6JC 2E31B 2Z8HA 4JGHC 4CXJA 3E4UA 4W9EB 5FTAA 5BXDA 3M8VA 5JH5B 4O1VA 1LDKD 4GWNA 4GHUA 4U2MA 1FLKA 1QDVA 1YY6A 4W9DB 2ASTA 3GA1A 5IBKA 2XXNA 3IVQA 4B9KE 1P22B 1LB6A 3ZRFB 1FQVB 2OVQA 3DCGB 5DAFA 4JJQA 3OGLA 3LNMB 4UIJA 5BXHA 1YZEA 3DRZA 1L0AA 5HZGC 1LB5A 1EOFA 1VCBB 4W9HH 4C9ZA 3KVTA 3OHVA 4YY8A 4B95B 5H7HA 2P1MA 4CP3A 3ZTCB 4B9KB 3B84A 4I7DA 2F1ZA 3HVEB 4W9FB 4ZOUA 3C6NA 1R29A 4I7BA 3HQHA 1EODA 1CA4A 2OVRA 4JTAB 1R28A 2P1OA 1FS2B 4BGCA 2IF5A 4W9CB 1CS3A 2A79B 3OGKA 1LQBB 2OVPA 1CZYA 1LB4A 4EOZA 3MQSC
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1X A;  4HXI A;  5BO4 C;  3M5B A;  1D0J A;  3BIM A;  2ASS A;  3ZTD B;  2GKW A;  4CRH A;  5E1T A;  1F3V B;  3V7D A;  3HVE A;  1QSC A;  2FOP A;  2P1Q A;  1D00 A;  2FOO A;  4M4E A;  2NN2 A;  5EUP A;  1NEX A;  4YSI A;  1CZZ A;  4UYI A;  5H7G A;  3ZUN B;  1FLL A;  1R2B A;  2P1N A;  2F1Y A;  4BKT B;  4U77 A;  2YY9 A;  2MA9 C;  4CXT A;  3HQI A;  2P1P A;  1KZZ A;  1LM8 C;  3ZNG B;  4U2N A;  3ZJB A;  4AJY C;  4W9L B;  4K8U A;  4APF A;  2JZ3 C;  2F1W A;  4W9J B;  3C6O A;  4KG9 A;  4W9I B;  1CA9 A;  2VPK A;  2Q81 A;  4W9G B;  5H9M A;  1NN7 A;  3HU6 A;  4GWM A;  3HTM A;  4W9K B;  2IHC A;  2PPI A;  3M52 A;  3LBZ A;  3ZKJ B;  4Z8M A;  1D0A A;  2CR2 A;  2I2R A;  3LUT B;  5DAD A;  3ZRC B;  4J8Z A;  5LLI B;  3MQR A;  3WSO B;  4X3G A;  3HQM A;  3HSV A;  3MKS A;  3FKC A;  5BXB A;  1EXB E;  3I3N A;  1D01 A;  4I7C A;  4N9F 5;  4AP2 A;  1S1G A;  1RF3 A;  2A25 A;  2E32 B;  3OGM A;  3OHU A;  2R9R B;  1DSX A;  4BKS B;  4GJH A;  5HYW B;  4JTC B;  1QDW A;  1EOE A;  3IVV A;  2FOJ A;  1K2F A;  4WQO C;  4W9H B;  2C9W C;  5A6R A;  3C6P A;  4CXI A;  4CA1 A;  1HV2 A;  2AN6 A;  3IVB A;  5A15 A;  2IZV C;  1BUO A;  3HQL A;  1ZMS A;  2NZ0 B;  3L2O A;  1FS1 B;  1A68 A;  2FNJ C;  3M4T A;  4AWJ B;  1T1D A;  2VKP A;  4JTD B;  4I6J C;  2E31 B;  2Z8H A;  4JGH C;  4CXJ A;  3E4U A;  4W9E B;  5FTA A;  5BXD A;  3M8V A;  5JH5 B;  4O1V A;  1LDK D;  4GWN A;  4GHU A;  4U2M A;  1FLK A;  1QDV A;  1YY6 A;  4W9D B;  2AST A;  3GA1 A;  5IBK A;  2XXN A;  3IVQ A;  4B9K E;  1P22 B;  1LB6 A;  3ZRF B;  1FQV B;  2OVQ A;  3DCG B;  5DAF A;  4JJQ A;  3OGL A;  3LNM B;  4UIJ A;  5BXH A;  1YZE A;  3DRZ A;  1L0A A;  5HZG C;  1LB5 A;  1EOF A;  1VCB B;  4W9H H;  4C9Z A;  3KVT A;  3OHV A;  4B95 B;  5H7H A;  2P1M A;  4CP3 A;  3ZTC B;  4B9K B;  3B84 A;  4I7D A;  2F1Z A;  3HVE B;  4W9F B;  4ZOU A;  3C6N A;  1R29 A;  4I7B A;  3HQH A;  1EOD A;  1CA4 A;  2OVR A;  4JTA B;  1R28 A;  2P1O A;  1FS2 B;  4BGC A;  2IF5 A;  4W9C B;  1CS3 A;  2A79 B;  3OGK A;  1LQB B;  2OVP A;  1CZY A;  1LB4 A;  4EOZ A;  3MQS C; 
#chains in the Genus database with same CATH topology
 2F1X A;  4HXI A;  5BO4 C;  3M5B A;  1D0J A;  3BIM A;  2ASS A;  3ZTD B;  2GKW A;  4CRH A;  5E1T A;  1F3V B;  3V7D A;  3HVE A;  1QSC A;  2FOP A;  2P1Q A;  1D00 A;  2FOO A;  4M4E A;  2NN2 A;  5EUP A;  1NEX A;  4YSI A;  1CZZ A;  4UYI A;  5H7G A;  3ZUN B;  1FLL A;  1R2B A;  2P1N A;  2F1Y A;  4BKT B;  4U77 A;  2YY9 A;  2MA9 C;  4CXT A;  3HQI A;  2P1P A;  1KZZ A;  1LM8 C;  3ZNG B;  4U2N A;  3ZJB A;  4AJY C;  4W9L B;  4K8U A;  4ZGC A;  4APF A;  2JZ3 C;  2F1W A;  4W9J B;  3C6O A;  4KG9 A;  4W9I B;  1CA9 A;  2VPK A;  2Q81 A;  4W9G B;  5H9M A;  1NN7 A;  3HU6 A;  4GWM A;  3DRY A;  3HTM A;  2IHC A;  2PPI A;  3M52 A;  4W9K B;  3LBZ A;  3ZKJ B;  4Z8M A;  1D0A A;  2CR2 A;  2I2R A;  3LUT B;  5DAD A;  3ZRC B;  4J8Z A;  5LLI B;  3MQR A;  3WSO B;  4X3G A;  3HQM A;  3HSV A;  3MKS A;  3FKC A;  5BXB A;  1EXB E;  3I3N A;  1D01 A;  4I7C A;  4N9F 5;  4AP2 A;  1S1G A;  1RF3 A;  2A25 A;  2E32 B;  3OGM A;  3OHU A;  2R9R B;  1DSX A;  4BKS B;  4GJH A;  5HYW B;  4JTC B;  1QDW A;  1EOE A;  3IVV A;  2FOJ A;  1K2F A;  4WQO C;  4W9H B;  2C9W C;  3DRX A;  5A6R A;  3C6P A;  4CXI A;  4CA1 A;  1HV2 A;  2AN6 A;  3IVB A;  5A15 A;  2IZV C;  1BUO A;  3HQL A;  1ZMS A;  2NZ0 B;  3L2O A;  1FS1 B;  1A68 A;  2FNJ C;  3M4T A;  4AWJ B;  1T1D A;  2VKP A;  4JTD B;  4I6J C;  2E31 B;  2Z8H A;  4JGH C;  4CXJ A;  3E4U A;  4W9E B;  5FTA A;  5BXD A;  3M8V A;  5JH5 B;  4O1V A;  1LDK D;  4GWN A;  4GHU A;  4U2M A;  1FLK A;  1QDV A;  1YY6 A;  4W9D B;  2AST A;  3GA1 A;  5IBK A;  2XXN A;  3IVQ A;  4B9K E;  1P22 B;  1LB6 A;  3ZRF B;  1FQV B;  2OVQ A;  3DCG B;  5DAF A;  4JJQ A;  3OGL A;  3LNM B;  4UIJ A;  5BXH A;  1YZE A;  3DRZ A;  1L0A A;  5HZG C;  1LB5 A;  1EOF A;  1VCB B;  4W9H H;  4C9Z A;  3KVT A;  3OHV A;  4YY8 A;  4B95 B;  5H7H A;  2P1M A;  4CP3 A;  3ZTC B;  4B9K B;  3B84 A;  4I7D A;  2F1Z A;  3HVE B;  4W9F B;  4ZOU A;  3C6N A;  1R29 A;  4I7B A;  3HQH A;  1EOD A;  1CA4 A;  2OVR A;  4JTA B;  1R28 A;  2P1O A;  1FS2 B;  4BGC A;  2IF5 A;  4W9C B;  1CS3 A;  2A79 B;  3OGK A;  1LQB B;  2OVP A;  1CZY A;  1LB4 A;  4EOZ A;  3MQS C; 
#chains in the Genus database with same CATH homology
 2F1X A;  4HXI A;  5BO4 C;  3M5B A;  1D0J A;  3BIM A;  2ASS A;  3ZTD B;  2GKW A;  4CRH A;  5E1T A;  1F3V B;  3V7D A;  3HVE A;  1QSC A;  2FOP A;  2P1Q A;  1D00 A;  2FOO A;  4M4E A;  2NN2 A;  5EUP A;  1NEX A;  4YSI A;  1CZZ A;  4UYI A;  5H7G A;  3ZUN B;  1FLL A;  1R2B A;  2P1N A;  2F1Y A;  4BKT B;  4U77 A;  2YY9 A;  2MA9 C;  4CXT A;  3HQI A;  2P1P A;  1KZZ A;  1LM8 C;  3ZNG B;  4U2N A;  3ZJB A;  4AJY C;  4W9L B;  4K8U A;  4ZGC A;  4APF A;  2JZ3 C;  2F1W A;  4W9J B;  3C6O A;  4KG9 A;  4W9I B;  1CA9 A;  2VPK A;  2Q81 A;  4W9G B;  5H9M A;  1NN7 A;  3HU6 A;  4GWM A;  3DRY A;  3HTM A;  2IHC A;  2PPI A;  3M52 A;  4W9K B;  3LBZ A;  3ZKJ B;  4Z8M A;  1D0A A;  2CR2 A;  2I2R A;  3LUT B;  5DAD A;  3ZRC B;  4J8Z A;  5LLI B;  3MQR A;  3WSO B;  4X3G A;  3HQM A;  3HSV A;  3MKS A;  3FKC A;  5BXB A;  1EXB E;  3I3N A;  1D01 A;  4I7C A;  4N9F 5;  4AP2 A;  1S1G A;  1RF3 A;  2A25 A;  2E32 B;  3OGM A;  3OHU A;  2R9R B;  1DSX A;  4BKS B;  4GJH A;  5HYW B;  4JTC B;  1QDW A;  1EOE A;  3IVV A;  2FOJ A;  1K2F A;  4WQO C;  4W9H B;  2C9W C;  3DRX A;  5A6R A;  3C6P A;  4CXI A;  4CA1 A;  1HV2 A;  2AN6 A;  3IVB A;  5A15 A;  2IZV C;  1BUO A;  3HQL A;  1ZMS A;  2NZ0 B;  3L2O A;  1FS1 B;  1A68 A;  2FNJ C;  3M4T A;  4AWJ B;  1T1D A;  2VKP A;  4JTD B;  4I6J C;  2E31 B;  2Z8H A;  4JGH C;  4CXJ A;  3E4U A;  4W9E B;  5FTA A;  5BXD A;  3M8V A;  5JH5 B;  4O1V A;  1LDK D;  4GWN A;  4GHU A;  4U2M A;  1FLK A;  1QDV A;  1YY6 A;  4W9D B;  2AST A;  3GA1 A;  5IBK A;  2XXN A;  3IVQ A;  4B9K E;  1P22 B;  1LB6 A;  3ZRF B;  1FQV B;  2OVQ A;  3DCG B;  5DAF A;  4JJQ A;  3OGL A;  3LNM B;  4UIJ A;  5BXH A;  1YZE A;  3DRZ A;  1L0A A;  5HZG C;  1LB5 A;  1EOF A;  1VCB B;  4W9H H;  4C9Z A;  3KVT A;  3OHV A;  4YY8 A;  4B95 B;  5H7H A;  2P1M A;  4CP3 A;  3ZTC B;  4B9K B;  3B84 A;  4I7D A;  2F1Z A;  3HVE B;  4W9F B;  4ZOU A;  3C6N A;  1R29 A;  4I7B A;  3HQH A;  1EOD A;  1CA4 A;  2OVR A;  4JTA B;  1R28 A;  2P1O A;  1FS2 B;  4BGC A;  2IF5 A;  4W9C B;  1CS3 A;  2A79 B;  3OGK A;  1LQB B;  2OVP A;  1CZY A;  1LB4 A;  4EOZ A;  3MQS C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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