3HU6 | Genus

Total Genus 64

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	64
sequence length	303
structure length	284
Chain Sequence	SKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSKLKWCLRVNPKGLDSKDYLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSQTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 284 atoms

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284 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Protein binding, ligase
source organism	Homo sapiens
publication title	Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. pubmed doi rcsb
molecule keywords	Speckle-type POZ protein
total genus	64
structure length	284
sequence length	303
chains with identical sequence	B
ec nomenclature
pdb deposition date	2009-06-13

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00651	BTB	BTB/POZ domain
A	PF00917	MATH	MATH domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.60.210.10	Mainly Beta	Sandwich	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A	3hu6A01
3.30.710.10	Alpha Beta	2-Layer Sandwich	Potassium Channel Kv1.1; Chain A	Potassium Channel Kv1.1; Chain A	3hu6A02

1VCBB 2P1PA 2F1WA 1DSXA 2FNJC 2I2RA 5IBKA 4U2MA 4JTDB 1D0JA 1QDVA 1EOFA 2NN2A 1FLLA 4X3GA 3I3NA 3C6OA 3GA1A 4W9EB 3ZNGB 5H9MA 2FOPA 4GJHA 2AN6A 1EOEA 1FS2B 2XXNA 5A15A 4CXIA 4C9ZA 1D01A 5BO4C 4CP3A 3HQMA 1L0AA 4JTAB 2R9RB 1FLKA 2F1XA 1CS3A 1EODA 3LUTB 1R28A 3M8VA 3OHUA 4AJYC 1D0AA 3M4TA 4AP2A 1S1GA 3LNMB 4BKTB 1ZMSA 1RF3A 4GWNA 4CRHA 1YY6A 4I7BA 3V7DA 2OVPA 3HTMA 3ZKJB 5BXBA 2FOJA 3E4UA 4B9KE 4CXTA 4CA1A 1EXBE 3OHVA 1LB5A 4B95B 3B84A 3DRZA 3HSVA 3KVTA 4CXJA 3HU6A 2IHCA 1HV2A 3DCGB 3OGMA 2P1QA 4W9HB 3IVQA 2A25A 4W9GB 3ZUNB 2PPIA 3MQSC 3ZRFB 4M4EA 1BUOA 3L2OA 2C9WC 3M52A 4EOZA 2P1MA 1NN7A 5JH5B 1T1DA 3C6NA 4YSIA 2E31B 5HYWB 2OVQA 3BIMA 4UYIA 4U2NA 2A79B 5H7GA 4UIJA 2YY9A 2VKPA 2Z8HA 1QDWA 4HXIA 1A68A 2MA9C 4JGHC 1NEXA 5A6RA 5E1TA 4WQOC 2P1OA 1R29A 5HZGC 2NZ0B 1KZZA 4N9F5 1YZEA 3FKCA 1FS1B 4B9KB 4W9IB 4BKSB 2IZVC 3IVVA 4Z8MA 3C6PA 3HQIA 3IVBA 3ZJBA 2P1NA 3WSOB 3LBZA 3HQLA 3MQRA 5H7HA 4K8UA 4APFA 4W9CB 4GWMA 4W9FB 3HQHA 1FQVB 4O1VA 1CA9A 4JTCB 3ZTDB 4U77A 2Q81A 1LQBB 2F1ZA 4W9DB 5DAFA 3HVEA 4JJQA 4BGCA 4AWJB 3M5BA 3OGKA 4KG9A 4I7DA 3HVEB 4W9LB 2GKWA 5BXDA 5BXHA 2F1YA 1CA4A 1LB4A 2FOOA 1QSCA 5LLIB 4W9HH 4I7CA 5FTAA 3ZRCB 1R2BA 4GHUA 1LB6A 1D00A 4ZOUA 3ZTCB 3OGLA 2ASTA 2JZ3C 1P22B 4W9JB 1LDKD 5DADA 4J8ZA 1F3VB 1CZZA 2E32B 5EUPA 2OVRA 1CZYA 4I6JC 2ASSA 2IF5A 1K2FA 2CR2A 3MKSA 2VPKA 4W9KB 1LM8C
chains in the Genus database with same CATH superfamily

1VCBB 2P1PA 2F1WA 1DSXA 2FNJC 2I2RA 5IBKA 4U2MA 4JTDB 1D0JA 1QDVA 1EOFA 2NN2A 1FLLA 4X3GA 3I3NA 3C6OA 3GA1A 4W9EB 3ZNGB 4YY8A 5H9MA 2FOPA 4GJHA 2AN6A 1EOEA 1FS2B 2XXNA 5A15A 4CXIA 4C9ZA 1D01A 5BO4C 4CP3A 3HQMA 1L0AA 4JTAB 2R9RB 1FLKA 2F1XA 1CS3A 1EODA 3LUTB 1R28A 3M8VA 3OHUA 4AJYC 1D0AA 3M4TA 4AP2A 1S1GA 3LNMB 4BKTB 1ZMSA 1RF3A 4GWNA 4CRHA 1YY6A 4I7BA 3V7DA 2OVPA 3HTMA 3ZKJB 5BXBA 2FOJA 3E4UA 4B9KE 4CXTA 4CA1A 1EXBE 3OHVA 1LB5A 4B95B 3B84A 3DRZA 3HSVA 3KVTA 4CXJA 3HU6A 2IHCA 1HV2A 3DCGB 3OGMA 2P1QA 4W9HB 3IVQA 2A25A 4W9GB 3ZUNB 2PPIA 3MQSC 3ZRFB 4M4EA 1BUOA 3L2OA 2C9WC 3M52A 4EOZA 2P1MA 1NN7A 5JH5B 1T1DA 3C6NA 4YSIA 2E31B 5HYWB 2OVQA 3BIMA 4UYIA 4U2NA 2A79B 5H7GA 4UIJA 2YY9A 2VKPA 2Z8HA 1QDWA 4HXIA 1A68A 2MA9C 4JGHC 1NEXA 5A6RA 5E1TA 4WQOC 2P1OA 1R29A 3DRXA 5HZGC 2NZ0B 1KZZA 4N9F5 1YZEA 3FKCA 1FS1B 4B9KB 4W9IB 4BKSB 2IZVC 3IVVA 4Z8MA 3C6PA 3HQIA 3IVBA 3ZJBA 2P1NA 3WSOB 3LBZA 3HQLA 3MQRA 5H7HA 4K8UA 4APFA 4W9CB 4GWMA 4W9FB 3HQHA 1FQVB 4O1VA 1CA9A 4JTCB 3ZTDB 4U77A 2Q81A 1LQBB 2F1ZA 4W9DB 5DAFA 3HVEA 4JJQA 4BGCA 4AWJB 3M5BA 4ZGCA 3OGKA 4KG9A 4I7DA 3HVEB 4W9LB 2GKWA 5BXDA 5BXHA 2F1YA 1CA4A 1LB4A 2FOOA 1QSCA 5LLIB 4W9HH 4I7CA 5FTAA 3ZRCB 1R2BA 4GHUA 3DRYA 1LB6A 1D00A 4ZOUA 3ZTCB 3OGLA 2ASTA 2JZ3C 1P22B 4W9JB 1LDKD 5DADA 4J8ZA 1F3VB 1CZZA 2E32B 5EUPA 2OVRA 1CZYA 4I6JC 2ASSA 2IF5A 1K2FA 2CR2A 3MKSA 2VPKA 4W9KB 1LM8C
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1VCB B;  2P1P A;  2F1W A;  1DSX A;  2FNJ C;  2I2R A;  5IBK A;  4U2M A;  4JTD B;  1D0J A;  1QDV A;  1EOF A;  2NN2 A;  1FLL A;  4X3G A;  3I3N A;  3C6O A;  3GA1 A;  4W9E B;  3ZNG B;  5H9M A;  2FOP A;  4GJH A;  2AN6 A;  1EOE A;  1FS2 B;  2XXN A;  5A15 A;  4CXI A;  4C9Z A;  1D01 A;  5BO4 C;  4CP3 A;  3HQM A;  1L0A A;  4JTA B;  2R9R B;  1FLK A;  2F1X A;  1CS3 A;  1EOD A;  3LUT B;  1R28 A;  3M8V A;  3OHU A;  4AJY C;  1D0A A;  3M4T A;  4AP2 A;  1S1G A;  3LNM B;  4BKT B;  1ZMS A;  1RF3 A;  4GWN A;  4CRH A;  1YY6 A;  4I7B A;  3V7D A;  2OVP A;  3HTM A;  3ZKJ B;  5BXB A;  2FOJ A;  3E4U A;  4B9K E;  4CXT A;  4CA1 A;  1EXB E;  3OHV A;  1LB5 A;  4B95 B;  3B84 A;  3DRZ A;  3HSV A;  3KVT A;  4CXJ A;  3HU6 A;  2IHC A;  1HV2 A;  3DCG B;  3OGM A;  2P1Q A;  4W9H B;  3IVQ A;  2A25 A;  4W9G B;  3ZUN B;  2PPI A;  3MQS C;  3ZRF B;  4M4E A;  1BUO A;  3L2O A;  2C9W C;  3M52 A;  4EOZ A;  2P1M A;  1NN7 A;  5JH5 B;  1T1D A;  3C6N A;  4YSI A;  2E31 B;  5HYW B;  2OVQ A;  3BIM A;  4UYI A;  4U2N A;  2A79 B;  5H7G A;  4UIJ A;  2YY9 A;  2VKP A;  2Z8H A;  1QDW A;  4HXI A;  1A68 A;  2MA9 C;  4JGH C;  1NEX A;  5A6R A;  5E1T A;  4WQO C;  2P1O A;  1R29 A;  5HZG C;  2NZ0 B;  1KZZ A;  4N9F 5;  1YZE A;  3FKC A;  1FS1 B;  4B9K B;  4W9I B;  4BKS B;  2IZV C;  3IVV A;  4Z8M A;  3C6P A;  3HQI A;  3IVB A;  3ZJB A;  2P1N A;  3WSO B;  3LBZ A;  3HQL A;  3MQR A;  5H7H A;  4K8U A;  4APF A;  4W9C B;  4GWM A;  4W9F B;  3HQH A;  1FQV B;  4O1V A;  1CA9 A;  4JTC B;  3ZTD B;  4U77 A;  2Q81 A;  1LQB B;  2F1Z A;  4W9D B;  5DAF A;  3HVE A;  4JJQ A;  4BGC A;  4AWJ B;  3M5B A;  3OGK A;  4KG9 A;  4I7D A;  3HVE B;  4W9L B;  2GKW A;  5BXD A;  5BXH A;  2F1Y A;  1CA4 A;  1LB4 A;  2FOO A;  1QSC A;  5LLI B;  4W9H H;  4I7C A;  5FTA A;  3ZRC B;  1R2B A;  4GHU A;  1LB6 A;  1D00 A;  4ZOU A;  3ZTC B;  3OGL A;  2AST A;  2JZ3 C;  1P22 B;  4W9J B;  1LDK D;  5DAD A;  4J8Z A;  1F3V B;  1CZZ A;  2E32 B;  5EUP A;  2OVR A;  1CZY A;  4I6J C;  2ASS A;  2IF5 A;  1K2F A;  2CR2 A;  3MKS A;  2VPK A;  4W9K B;  1LM8 C; 
#chains in the Genus database with same CATH topology
 1VCB B;  2P1P A;  2F1W A;  1DSX A;  2FNJ C;  2I2R A;  5IBK A;  4U2M A;  4JTD B;  1D0J A;  1QDV A;  1EOF A;  2NN2 A;  1FLL A;  4X3G A;  3I3N A;  3C6O A;  3GA1 A;  4W9E B;  3ZNG B;  4YY8 A;  5H9M A;  2FOP A;  4GJH A;  2AN6 A;  1EOE A;  1FS2 B;  2XXN A;  5A15 A;  4CXI A;  4C9Z A;  1D01 A;  5BO4 C;  4CP3 A;  3HQM A;  1L0A A;  4JTA B;  2R9R B;  1FLK A;  2F1X A;  1CS3 A;  1EOD A;  3LUT B;  1R28 A;  3M8V A;  3OHU A;  4AJY C;  1D0A A;  3M4T A;  4AP2 A;  1S1G A;  3LNM B;  4BKT B;  1ZMS A;  1RF3 A;  4GWN A;  4CRH A;  1YY6 A;  4I7B A;  3V7D A;  2OVP A;  3HTM A;  3ZKJ B;  5BXB A;  2FOJ A;  3E4U A;  4B9K E;  4CXT A;  4CA1 A;  1EXB E;  3OHV A;  1LB5 A;  4B95 B;  3B84 A;  3DRZ A;  3HSV A;  3KVT A;  4CXJ A;  3HU6 A;  2IHC A;  1HV2 A;  3DCG B;  3OGM A;  2P1Q A;  4W9H B;  3IVQ A;  2A25 A;  4W9G B;  3ZUN B;  2PPI A;  3MQS C;  3ZRF B;  4M4E A;  1BUO A;  3L2O A;  2C9W C;  3M52 A;  4EOZ A;  2P1M A;  1NN7 A;  5JH5 B;  1T1D A;  3C6N A;  4YSI A;  2E31 B;  5HYW B;  2OVQ A;  3BIM A;  4UYI A;  4U2N A;  2A79 B;  5H7G A;  4UIJ A;  2YY9 A;  2VKP A;  2Z8H A;  1QDW A;  4HXI A;  1A68 A;  2MA9 C;  4JGH C;  1NEX A;  5A6R A;  5E1T A;  4WQO C;  2P1O A;  1R29 A;  3DRX A;  5HZG C;  2NZ0 B;  1KZZ A;  4N9F 5;  1YZE A;  3FKC A;  1FS1 B;  4B9K B;  4W9I B;  4BKS B;  2IZV C;  3IVV A;  4Z8M A;  3C6P A;  3HQI A;  3IVB A;  3ZJB A;  2P1N A;  3WSO B;  3LBZ A;  3HQL A;  3MQR A;  5H7H A;  4K8U A;  4APF A;  4W9C B;  4GWM A;  4W9F B;  3HQH A;  1FQV B;  4O1V A;  1CA9 A;  4JTC B;  3ZTD B;  4U77 A;  2Q81 A;  1LQB B;  2F1Z A;  4W9D B;  5DAF A;  3HVE A;  4JJQ A;  4BGC A;  4AWJ B;  3M5B A;  4ZGC A;  3OGK A;  4KG9 A;  4I7D A;  3HVE B;  4W9L B;  2GKW A;  5BXD A;  5BXH A;  2F1Y A;  1CA4 A;  1LB4 A;  2FOO A;  1QSC A;  5LLI B;  4W9H H;  4I7C A;  5FTA A;  3ZRC B;  1R2B A;  4GHU A;  3DRY A;  1LB6 A;  1D00 A;  4ZOU A;  3ZTC B;  3OGL A;  2AST A;  2JZ3 C;  1P22 B;  4W9J B;  1LDK D;  5DAD A;  4J8Z A;  1F3V B;  1CZZ A;  2E32 B;  5EUP A;  2OVR A;  1CZY A;  4I6J C;  2ASS A;  2IF5 A;  1K2F A;  2CR2 A;  3MKS A;  2VPK A;  4W9K B;  1LM8 C; 
#chains in the Genus database with same CATH homology
 1VCB B;  2P1P A;  2F1W A;  1DSX A;  2FNJ C;  2I2R A;  5IBK A;  4U2M A;  4JTD B;  1D0J A;  1QDV A;  1EOF A;  2NN2 A;  1FLL A;  4X3G A;  3I3N A;  3C6O A;  3GA1 A;  4W9E B;  3ZNG B;  4YY8 A;  5H9M A;  2FOP A;  4GJH A;  2AN6 A;  1EOE A;  1FS2 B;  2XXN A;  5A15 A;  4CXI A;  4C9Z A;  1D01 A;  5BO4 C;  4CP3 A;  3HQM A;  1L0A A;  4JTA B;  2R9R B;  1FLK A;  2F1X A;  1CS3 A;  1EOD A;  3LUT B;  1R28 A;  3M8V A;  3OHU A;  4AJY C;  1D0A A;  3M4T A;  4AP2 A;  1S1G A;  3LNM B;  4BKT B;  1ZMS A;  1RF3 A;  4GWN A;  4CRH A;  1YY6 A;  4I7B A;  3V7D A;  2OVP A;  3HTM A;  3ZKJ B;  5BXB A;  2FOJ A;  3E4U A;  4B9K E;  4CXT A;  4CA1 A;  1EXB E;  3OHV A;  1LB5 A;  4B95 B;  3B84 A;  3DRZ A;  3HSV A;  3KVT A;  4CXJ A;  3HU6 A;  2IHC A;  1HV2 A;  3DCG B;  3OGM A;  2P1Q A;  4W9H B;  3IVQ A;  2A25 A;  4W9G B;  3ZUN B;  2PPI A;  3MQS C;  3ZRF B;  4M4E A;  1BUO A;  3L2O A;  2C9W C;  3M52 A;  4EOZ A;  2P1M A;  1NN7 A;  5JH5 B;  1T1D A;  3C6N A;  4YSI A;  2E31 B;  5HYW B;  2OVQ A;  3BIM A;  4UYI A;  4U2N A;  2A79 B;  5H7G A;  4UIJ A;  2YY9 A;  2VKP A;  2Z8H A;  1QDW A;  4HXI A;  1A68 A;  2MA9 C;  4JGH C;  1NEX A;  5A6R A;  5E1T A;  4WQO C;  2P1O A;  1R29 A;  3DRX A;  5HZG C;  2NZ0 B;  1KZZ A;  4N9F 5;  1YZE A;  3FKC A;  1FS1 B;  4B9K B;  4W9I B;  4BKS B;  2IZV C;  3IVV A;  4Z8M A;  3C6P A;  3HQI A;  3IVB A;  3ZJB A;  2P1N A;  3WSO B;  3LBZ A;  3HQL A;  3MQR A;  5H7H A;  4K8U A;  4APF A;  4W9C B;  4GWM A;  4W9F B;  3HQH A;  1FQV B;  4O1V A;  1CA9 A;  4JTC B;  3ZTD B;  4U77 A;  2Q81 A;  1LQB B;  2F1Z A;  4W9D B;  5DAF A;  3HVE A;  4JJQ A;  4BGC A;  4AWJ B;  3M5B A;  4ZGC A;  3OGK A;  4KG9 A;  4I7D A;  3HVE B;  4W9L B;  2GKW A;  5BXD A;  5BXH A;  2F1Y A;  1CA4 A;  1LB4 A;  2FOO A;  1QSC A;  5LLI B;  4W9H H;  4I7C A;  5FTA A;  3ZRC B;  1R2B A;  4GHU A;  3DRY A;  1LB6 A;  1D00 A;  4ZOU A;  3ZTC B;  3OGL A;  2AST A;  2JZ3 C;  1P22 B;  4W9J B;  1LDK D;  5DAD A;  4J8Z A;  1F3V B;  1CZZ A;  2E32 B;  5EUP A;  2OVR A;  1CZY A;  4I6J C;  2ASS A;  2IF5 A;  1K2F A;  2CR2 A;  3MKS A;  2VPK A;  4W9K B;  1LM8 C;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3HU6A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations