3HU6A

Structures of spop-substrate complexes: insights into molecular architectures of btb-cul3 ubiquitin ligases: spopmathx/btb/3-box-pucsbc1
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
303
structure length
284
Chain Sequence
SKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSKLKWCLRVNPKGLDSKDYLSLYLLLVSCPKEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRGFLLDEANGLLPDDKLTLFCEVSVVQDSQTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
pubmed doi rcsb
molecule tags Protein binding, ligase
source organism Homo sapiens
molecule keywords Speckle-type POZ protein
total genus 64
structure length 284
sequence length 303
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-06-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00651 BTB BTB/POZ domain
A PF00917 MATH MATH domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.210.10 Mainly Beta Sandwich Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2; Chain A 3hu6A01
3.30.710.10 Alpha Beta 2-Layer Sandwich Potassium Channel Kv1.1; Chain A Potassium Channel Kv1.1; Chain A 3hu6A02
1K2FA 4W9KB 1FQVB 1D00A 1F3VB 4W9GB 3ZRCB 4B9KB 2ASSA 3HVEB 2GKWA 1S1GA 3ZNGB 4AJYC 4CP3A 5E1TA 1EOFA 1QDWA 5HYWB 4U2MA 4K8UA 1HV2A 4UIJA 4I7DA 4X3GA 5BO4C 2P1NA 2F1WA 4UYIA 1R2BA 2MA9C 4GJHA 4M4EA 2E32B 2F1ZA 3C6OA 5H9MA 4C9ZA 3E4UA 4W9CB 1FS2B 3IVQA 2CR2A 2FOPA 4HXIA 4EOZA 4JTCB 2R9RB 5LLIB 4JJQA 1QSCA 2FOJA 1P22B 3C6NA 4BGCA 4ZOUA 3M8VA 4BKTB 3MQRA 3B84A 2JZ3C 1EXBE 3WSOB 5BXDA 4U77A 4W9FB 1D01A 2A25A 3HQIA 4Z8MA 1DSXA 2NN2A 3ZTCB 4GHUA 3IVBA 2FNJC 5HZGC 4WQOC 5H7GA 1CZYA 2YY9A 2F1YA 5DAFA 3HQMA 2C9WC 4JGHC 4GWMA 3C6PA 2IF5A 4JTAB 4CXTA 2P1OA 3ZUNB 2E31B 3LNMB 2IZVC 3DCGB 1LB4A 1NN7A 5JH5B 3HSVA 1LB6A 3GA1A 3DRZA 4CXJA 1KZZA 2P1QA 3MQSC 2OVRA 2OVQA 4AWJB 1CZZA 5DADA 3ZJBA 2AN6A 4I6JC 4O1VA 1CA9A 1R29A 3LUTB 4U2NA 4AP2A 1CA4A 3BIMA 2XXNA 3OHUA 4W9HH 3HU6A 1VCBB 1D0JA 4B95B 1LDKD 3OGMA 3V7DA 2A79B 4W9IB 3I3NA 1FLKA 3MKSA 4I7CA 5IBKA 3HVEA 1EOEA 4KG9A 4APFA 1LB5A 2VPKA 1L0AA 3M5BA 1ZMSA 1BUOA 4JTDB 2I2RA 3ZKJB 2IHCA 2ASTA 1YZEA 1D0AA 1RF3A 3HQLA 2P1PA 3M4TA 1R28A 2NZ0B 2F1XA 3IVVA 4W9JB 5H7HA 4W9LB 5BXHA 4B9KE 3HQHA 3L2OA 5FTAA 4GWNA 1FLLA 3LBZA 1LQBB 3OGLA 2FOOA 1CS3A 2P1MA 4W9DB 4BKSB 3HTMA 3ZRFB 1FS1B 4CXIA 4W9HB 5BXBA 1NEXA 4W9EB 5A6RA 4CA1A 1EODA 1LM8C 4YSIA 4CRHA 4I7BA 2OVPA 3OGKA 2Q81A 4J8ZA 5A15A 1YY6A 1A68A 3FKCA 2PPIA 1T1DA 3OHVA 4N9F5 3M52A 1QDVA 2VKPA 2Z8HA 3ZTDB 3KVTA 5EUPA
chains in the Genus database with same CATH superfamily
1K2FA 4W9KB 1FQVB 1D00A 1F3VB 4W9GB 3ZRCB 4B9KB 2ASSA 3HVEB 2GKWA 1S1GA 3ZNGB 4AJYC 4CP3A 5E1TA 1EOFA 1QDWA 5HYWB 4U2MA 4K8UA 1HV2A 4UIJA 4I7DA 4X3GA 5BO4C 2P1NA 4ZGCA 2F1WA 4UYIA 1R2BA 2MA9C 4GJHA 4M4EA 2E32B 2F1ZA 3C6OA 5H9MA 4C9ZA 3E4UA 4W9CB 1FS2B 3IVQA 2CR2A 2FOPA 4HXIA 4EOZA 4JTCB 2R9RB 5LLIB 4JJQA 1QSCA 2FOJA 1P22B 3C6NA 4BGCA 4ZOUA 3M8VA 4BKTB 3MQRA 3B84A 2JZ3C 1EXBE 3WSOB 5BXDA 4U77A 4W9FB 1D01A 2A25A 3HQIA 4Z8MA 1DSXA 2NN2A 3ZTCB 4GHUA 3IVBA 2FNJC 5HZGC 4WQOC 5H7GA 1CZYA 2YY9A 2F1YA 5DAFA 3HQMA 2C9WC 4YY8A 4JGHC 4GWMA 3C6PA 2IF5A 4JTAB 4CXTA 2P1OA 3ZUNB 2E31B 3LNMB 2IZVC 3DCGB 1LB4A 1NN7A 5JH5B 3HSVA 1LB6A 3GA1A 3DRZA 4CXJA 1KZZA 2P1QA 3MQSC 2OVRA 2OVQA 4AWJB 1CZZA 5DADA 3ZJBA 2AN6A 4I6JC 4O1VA 1CA9A 1R29A 3LUTB 4U2NA 4AP2A 1CA4A 3BIMA 2XXNA 3OHUA 4W9HH 3HU6A 1VCBB 1D0JA 4B95B 1LDKD 3OGMA 3V7DA 2A79B 4W9IB 3I3NA 1FLKA 3MKSA 4I7CA 5IBKA 3HVEA 1EOEA 4KG9A 4APFA 1LB5A 2VPKA 1L0AA 3M5BA 1ZMSA 1BUOA 4JTDB 2I2RA 3ZKJB 2IHCA 2ASTA 1YZEA 1D0AA 1RF3A 3HQLA 2P1PA 3M4TA 1R28A 2NZ0B 2F1XA 3IVVA 4W9JB 5H7HA 4W9LB 5BXHA 4B9KE 3HQHA 3L2OA 3DRYA 5FTAA 4GWNA 1FLLA 3LBZA 1LQBB 3OGLA 2FOOA 1CS3A 2P1MA 4W9DB 4BKSB 3HTMA 3ZRFB 1FS1B 4CXIA 4W9HB 5BXBA 1NEXA 4W9EB 5A6RA 4CA1A 1EODA 1LM8C 4YSIA 4CRHA 4I7BA 2OVPA 3OGKA 2Q81A 4J8ZA 5A15A 1YY6A 1A68A 3FKCA 2PPIA 1T1DA 3OHVA 4N9F5 3M52A 1QDVA 2VKPA 2Z8HA 3DRXA 3ZTDB 3KVTA 5EUPA
chains in the Genus database with same CATH topology
1K2FA 4W9KB 1FQVB 1D00A 1F3VB 4W9GB 3ZRCB 4B9KB 2ASSA 3HVEB 2GKWA 1S1GA 3ZNGB 4AJYC 4CP3A 5E1TA 1EOFA 1QDWA 5HYWB 4U2MA 4K8UA 1HV2A 4UIJA 4I7DA 4X3GA 5BO4C 2P1NA 4ZGCA 2F1WA 4UYIA 1R2BA 2MA9C 4GJHA 4M4EA 2E32B 2F1ZA 3C6OA 5H9MA 4C9ZA 3E4UA 4W9CB 1FS2B 3IVQA 2CR2A 2FOPA 4HXIA 4EOZA 4JTCB 2R9RB 5LLIB 4JJQA 1QSCA 2FOJA 1P22B 3C6NA 4BGCA 4ZOUA 3M8VA 4BKTB 3MQRA 3B84A 2JZ3C 1EXBE 3WSOB 5BXDA 4U77A 4W9FB 1D01A 2A25A 3HQIA 4Z8MA 1DSXA 2NN2A 3ZTCB 4GHUA 3IVBA 2FNJC 5HZGC 4WQOC 5H7GA 1CZYA 2YY9A 2F1YA 5DAFA 3HQMA 2C9WC 4YY8A 4JGHC 4GWMA 3C6PA 2IF5A 4JTAB 4CXTA 2P1OA 3ZUNB 2E31B 3LNMB 2IZVC 3DCGB 1LB4A 1NN7A 5JH5B 3HSVA 1LB6A 3GA1A 3DRZA 4CXJA 1KZZA 2P1QA 3MQSC 2OVRA 2OVQA 4AWJB 1CZZA 5DADA 3ZJBA 2AN6A 4I6JC 4O1VA 1CA9A 1R29A 3LUTB 4U2NA 4AP2A 1CA4A 3BIMA 2XXNA 3OHUA 4W9HH 3HU6A 1VCBB 1D0JA 4B95B 1LDKD 3OGMA 3V7DA 2A79B 4W9IB 3I3NA 1FLKA 3MKSA 4I7CA 5IBKA 3HVEA 1EOEA 4KG9A 4APFA 1LB5A 2VPKA 1L0AA 3M5BA 1ZMSA 1BUOA 4JTDB 2I2RA 3ZKJB 2IHCA 2ASTA 1YZEA 1D0AA 1RF3A 3HQLA 2P1PA 3M4TA 1R28A 2NZ0B 2F1XA 3IVVA 4W9JB 5H7HA 4W9LB 5BXHA 4B9KE 3HQHA 3L2OA 3DRYA 5FTAA 4GWNA 1FLLA 3LBZA 1LQBB 3OGLA 2FOOA 1CS3A 2P1MA 4W9DB 4BKSB 3HTMA 3ZRFB 1FS1B 4CXIA 4W9HB 5BXBA 1NEXA 4W9EB 5A6RA 4CA1A 1EODA 1LM8C 4YSIA 4CRHA 4I7BA 2OVPA 3OGKA 2Q81A 4J8ZA 5A15A 1YY6A 1A68A 3FKCA 2PPIA 1T1DA 3OHVA 4N9F5 3M52A 1QDVA 2VKPA 2Z8HA 3DRXA 3ZTDB 3KVTA 5EUPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1K2F A;  4W9K B;  1FQV B;  1D00 A;  1F3V B;  4W9G B;  3ZRC B;  4B9K B;  2ASS A;  3HVE B;  2GKW A;  1S1G A;  3ZNG B;  4AJY C;  4CP3 A;  5E1T A;  1EOF A;  1QDW A;  5HYW B;  4U2M A;  4K8U A;  1HV2 A;  4UIJ A;  4I7D A;  4X3G A;  5BO4 C;  2P1N A;  2F1W A;  4UYI A;  1R2B A;  2MA9 C;  4GJH A;  4M4E A;  2E32 B;  2F1Z A;  3C6O A;  5H9M A;  4C9Z A;  3E4U A;  4W9C B;  1FS2 B;  3IVQ A;  2CR2 A;  2FOP A;  4HXI A;  4EOZ A;  4JTC B;  2R9R B;  5LLI B;  4JJQ A;  1QSC A;  2FOJ A;  1P22 B;  3C6N A;  4BGC A;  4ZOU A;  3M8V A;  4BKT B;  3MQR A;  3B84 A;  2JZ3 C;  1EXB E;  3WSO B;  5BXD A;  4U77 A;  4W9F B;  1D01 A;  2A25 A;  3HQI A;  4Z8M A;  1DSX A;  2NN2 A;  3ZTC B;  4GHU A;  3IVB A;  2FNJ C;  5HZG C;  4WQO C;  5H7G A;  1CZY A;  2YY9 A;  2F1Y A;  5DAF A;  3HQM A;  2C9W C;  4JGH C;  4GWM A;  3C6P A;  2IF5 A;  4JTA B;  4CXT A;  2P1O A;  3ZUN B;  2E31 B;  3LNM B;  2IZV C;  3DCG B;  1LB4 A;  1NN7 A;  5JH5 B;  3HSV A;  1LB6 A;  3GA1 A;  3DRZ A;  4CXJ A;  1KZZ A;  2P1Q A;  3MQS C;  2OVR A;  2OVQ A;  4AWJ B;  1CZZ A;  5DAD A;  3ZJB A;  2AN6 A;  4I6J C;  4O1V A;  1CA9 A;  1R29 A;  3LUT B;  4U2N A;  4AP2 A;  1CA4 A;  3BIM A;  2XXN A;  3OHU A;  4W9H H;  3HU6 A;  1VCB B;  1D0J A;  4B95 B;  1LDK D;  3OGM A;  3V7D A;  2A79 B;  4W9I B;  3I3N A;  1FLK A;  3MKS A;  4I7C A;  5IBK A;  3HVE A;  1EOE A;  4KG9 A;  4APF A;  1LB5 A;  2VPK A;  1L0A A;  3M5B A;  1ZMS A;  1BUO A;  4JTD B;  2I2R A;  3ZKJ B;  2IHC A;  2AST A;  1YZE A;  1D0A A;  1RF3 A;  3HQL A;  2P1P A;  3M4T A;  1R28 A;  2NZ0 B;  2F1X A;  3IVV A;  4W9J B;  5H7H A;  4W9L B;  5BXH A;  4B9K E;  3HQH A;  3L2O A;  5FTA A;  4GWN A;  1FLL A;  3LBZ A;  1LQB B;  3OGL A;  2FOO A;  1CS3 A;  2P1M A;  4W9D B;  4BKS B;  3HTM A;  3ZRF B;  1FS1 B;  4CXI A;  4W9H B;  5BXB A;  1NEX A;  4W9E B;  5A6R A;  4CA1 A;  1EOD A;  1LM8 C;  4YSI A;  4CRH A;  4I7B A;  2OVP A;  3OGK A;  2Q81 A;  4J8Z A;  5A15 A;  1YY6 A;  1A68 A;  3FKC A;  2PPI A;  1T1D A;  3OHV A;  4N9F 5;  3M52 A;  1QDV A;  2VKP A;  2Z8H A;  3ZTD B;  3KVT A;  5EUP A; 
#chains in the Genus database with same CATH topology
 1K2F A;  4W9K B;  1FQV B;  1D00 A;  1F3V B;  4W9G B;  3ZRC B;  4B9K B;  2ASS A;  3HVE B;  2GKW A;  1S1G A;  3ZNG B;  4AJY C;  4CP3 A;  5E1T A;  1EOF A;  1QDW A;  5HYW B;  4U2M A;  4K8U A;  1HV2 A;  4UIJ A;  4I7D A;  4X3G A;  5BO4 C;  2P1N A;  4ZGC A;  2F1W A;  4UYI A;  1R2B A;  2MA9 C;  4GJH A;  4M4E A;  2E32 B;  2F1Z A;  3C6O A;  5H9M A;  4C9Z A;  3E4U A;  4W9C B;  1FS2 B;  3IVQ A;  2CR2 A;  2FOP A;  4HXI A;  4EOZ A;  4JTC B;  2R9R B;  5LLI B;  4JJQ A;  1QSC A;  2FOJ A;  1P22 B;  3C6N A;  4BGC A;  4ZOU A;  3M8V A;  4BKT B;  3MQR A;  3B84 A;  2JZ3 C;  1EXB E;  3WSO B;  5BXD A;  4U77 A;  4W9F B;  1D01 A;  2A25 A;  3HQI A;  4Z8M A;  1DSX A;  2NN2 A;  3ZTC B;  4GHU A;  3IVB A;  2FNJ C;  5HZG C;  4WQO C;  5H7G A;  1CZY A;  2YY9 A;  2F1Y A;  5DAF A;  3HQM A;  2C9W C;  4YY8 A;  4JGH C;  4GWM A;  3C6P A;  2IF5 A;  4JTA B;  4CXT A;  2P1O A;  3ZUN B;  2E31 B;  3LNM B;  2IZV C;  3DCG B;  1LB4 A;  1NN7 A;  5JH5 B;  3HSV A;  1LB6 A;  3GA1 A;  3DRZ A;  4CXJ A;  1KZZ A;  2P1Q A;  3MQS C;  2OVR A;  2OVQ A;  4AWJ B;  1CZZ A;  5DAD A;  3ZJB A;  2AN6 A;  4I6J C;  4O1V A;  1CA9 A;  1R29 A;  3LUT B;  4U2N A;  4AP2 A;  1CA4 A;  3BIM A;  2XXN A;  3OHU A;  4W9H H;  3HU6 A;  1VCB B;  1D0J A;  4B95 B;  1LDK D;  3OGM A;  3V7D A;  2A79 B;  4W9I B;  3I3N A;  1FLK A;  3MKS A;  4I7C A;  5IBK A;  3HVE A;  1EOE A;  4KG9 A;  4APF A;  1LB5 A;  2VPK A;  1L0A A;  3M5B A;  1ZMS A;  1BUO A;  4JTD B;  2I2R A;  3ZKJ B;  2IHC A;  2AST A;  1YZE A;  1D0A A;  1RF3 A;  3HQL A;  2P1P A;  3M4T A;  1R28 A;  2NZ0 B;  2F1X A;  3IVV A;  4W9J B;  5H7H A;  4W9L B;  5BXH A;  4B9K E;  3HQH A;  3L2O A;  3DRY A;  5FTA A;  4GWN A;  1FLL A;  3LBZ A;  1LQB B;  3OGL A;  2FOO A;  1CS3 A;  2P1M A;  4W9D B;  4BKS B;  3HTM A;  3ZRF B;  1FS1 B;  4CXI A;  4W9H B;  5BXB A;  1NEX A;  4W9E B;  5A6R A;  4CA1 A;  1EOD A;  1LM8 C;  4YSI A;  4CRH A;  4I7B A;  2OVP A;  3OGK A;  2Q81 A;  4J8Z A;  5A15 A;  1YY6 A;  1A68 A;  3FKC A;  2PPI A;  1T1D A;  3OHV A;  4N9F 5;  3M52 A;  1QDV A;  2VKP A;  2Z8H A;  3DRX A;  3ZTD B;  3KVT A;  5EUP A; 
#chains in the Genus database with same CATH homology
 1K2F A;  4W9K B;  1FQV B;  1D00 A;  1F3V B;  4W9G B;  3ZRC B;  4B9K B;  2ASS A;  3HVE B;  2GKW A;  1S1G A;  3ZNG B;  4AJY C;  4CP3 A;  5E1T A;  1EOF A;  1QDW A;  5HYW B;  4U2M A;  4K8U A;  1HV2 A;  4UIJ A;  4I7D A;  4X3G A;  5BO4 C;  2P1N A;  4ZGC A;  2F1W A;  4UYI A;  1R2B A;  2MA9 C;  4GJH A;  4M4E A;  2E32 B;  2F1Z A;  3C6O A;  5H9M A;  4C9Z A;  3E4U A;  4W9C B;  1FS2 B;  3IVQ A;  2CR2 A;  2FOP A;  4HXI A;  4EOZ A;  4JTC B;  2R9R B;  5LLI B;  4JJQ A;  1QSC A;  2FOJ A;  1P22 B;  3C6N A;  4BGC A;  4ZOU A;  3M8V A;  4BKT B;  3MQR A;  3B84 A;  2JZ3 C;  1EXB E;  3WSO B;  5BXD A;  4U77 A;  4W9F B;  1D01 A;  2A25 A;  3HQI A;  4Z8M A;  1DSX A;  2NN2 A;  3ZTC B;  4GHU A;  3IVB A;  2FNJ C;  5HZG C;  4WQO C;  5H7G A;  1CZY A;  2YY9 A;  2F1Y A;  5DAF A;  3HQM A;  2C9W C;  4YY8 A;  4JGH C;  4GWM A;  3C6P A;  2IF5 A;  4JTA B;  4CXT A;  2P1O A;  3ZUN B;  2E31 B;  3LNM B;  2IZV C;  3DCG B;  1LB4 A;  1NN7 A;  5JH5 B;  3HSV A;  1LB6 A;  3GA1 A;  3DRZ A;  4CXJ A;  1KZZ A;  2P1Q A;  3MQS C;  2OVR A;  2OVQ A;  4AWJ B;  1CZZ A;  5DAD A;  3ZJB A;  2AN6 A;  4I6J C;  4O1V A;  1CA9 A;  1R29 A;  3LUT B;  4U2N A;  4AP2 A;  1CA4 A;  3BIM A;  2XXN A;  3OHU A;  4W9H H;  3HU6 A;  1VCB B;  1D0J A;  4B95 B;  1LDK D;  3OGM A;  3V7D A;  2A79 B;  4W9I B;  3I3N A;  1FLK A;  3MKS A;  4I7C A;  5IBK A;  3HVE A;  1EOE A;  4KG9 A;  4APF A;  1LB5 A;  2VPK A;  1L0A A;  3M5B A;  1ZMS A;  1BUO A;  4JTD B;  2I2R A;  3ZKJ B;  2IHC A;  2AST A;  1YZE A;  1D0A A;  1RF3 A;  3HQL A;  2P1P A;  3M4T A;  1R28 A;  2NZ0 B;  2F1X A;  3IVV A;  4W9J B;  5H7H A;  4W9L B;  5BXH A;  4B9K E;  3HQH A;  3L2O A;  3DRY A;  5FTA A;  4GWN A;  1FLL A;  3LBZ A;  1LQB B;  3OGL A;  2FOO A;  1CS3 A;  2P1M A;  4W9D B;  4BKS B;  3HTM A;  3ZRF B;  1FS1 B;  4CXI A;  4W9H B;  5BXB A;  1NEX A;  4W9E B;  5A6R A;  4CA1 A;  1EOD A;  1LM8 C;  4YSI A;  4CRH A;  4I7B A;  2OVP A;  3OGK A;  2Q81 A;  4J8Z A;  5A15 A;  1YY6 A;  1A68 A;  3FKC A;  2PPI A;  1T1D A;  3OHV A;  4N9F 5;  3M52 A;  1QDV A;  2VKP A;  2Z8H A;  3DRX A;  3ZTD B;  3KVT A;  5EUP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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