1R3FA

Crystal structure of trna pseudouridine synthase trub and its rna complex: rna-protein recognition through a combination of rigid docking and induced fit
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
307
structure length
278
Chain Sequence
GRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of tRNA Pseudouridine Synthase TruB and Its RNA Complex: RNA Recognition Through a Combination of Rigid Docking and Induced Fit
pubmed doi rcsb
molecule tags Lyase
source organism Escherichia coli
molecule keywords tRNA pseudouridine synthase B
total genus 79
structure length 278
sequence length 307
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2003-10-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF09157 TruB-C_2 Pseudouridine synthase II TruB, C-terminal
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1r3fA02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1r3fA01
1KSKA 2EY4A 3LWQA 3LDFA 1SGVA 3VSEA 1V9FA 3LWOA 2Q07A 2HVYA 1ZE2A 1K8WA 1J2BA 3HJYA 3MQKA 3D79A 3UAIA 3LWPA 2CX1A 2J5VA 3HAXA 1KSLA 2CX0A 1T5YA 1IT8A 1IQ8A 2AB4A 1Q7HA 3HJWA 1PRZA 2APOA 1ZS7A 1WXXA 2I82A 1QYUA 2AS0A 2CWWA 3LWVA 1ZL3A 1R3EA 1R3FA 1IT7A 2J5TA 3DH3A 1SQWA 1XPIA 4LABA 1ZE1A 2AUSA 4Q1TA 4DMGA 1KSVA 3C0KA 2P38A 3U28A 3LWRA 2RFKA 4LGTA 2ISTA 1V9KA 2B78A 1WXWA
chains in the Genus database with same CATH superfamily
2EY4A 1V9FA 3LWOA 3LWPA 2CX1A 3HJWA 2Z0TA 3M6VA 3M65A 1TE7A 4CI2B 1WXXA 1QYUA 2CWWA 3LWVA 2DP9A 4LABA 4Q1TA 4DMGA 1Z2ZA 3U28A 2P38A 2RFKA 2B78A 1S04A 3M4XA 3LWQA 1SGVA 3VSEA 1K8WA 3HJYA 3M6XA 3D79A 2J5VA 1T5YA 1Q7HA 2FRXA 2APOA 1ZS7A 3IUWA 4TZ4C 1IT7A 2KKUA 2J5TA 1SQWA 3M6WA 2E5OA 1ZE1A 2AUSA 3C0KA 2ANEA 4LGTA 2ISTA 1KSKA 1XNEA 1ZE2A 1J2BA 3MQKA 4CI1B 1KSLA 1IT8A 1IQ8A 1UOYA 2AS0A 1R3EA 3DH3A 1XPIA 1SZWA 3LWRA 3M6UA 4CI3B 3LDFA 3LJCA 2HVYA 2Q07A 3UAIA 3HAXA 2CX0A 1SB7A 2AB4A 1PRZA 3ZV0C 2I82A 1ZL3A 1R3FA 1ZBOA 1WK2A 1KSVA 1SI7A 1V9KA 1WXWA
chains in the Genus database with same CATH topology
1KSKA 2EY4A 3LWQA 3LDFA 1SGVA 3VSEA 1V9FA 3LWOA 2Q07A 2HVYA 1ZE2A 1K8WA 1J2BA 3HJYA 3MQKA 3D79A 3UAIA 3LWPA 2CX1A 2J5VA 3HAXA 1KSLA 2CX0A 1SB7A 1T5YA 1IT8A 1IQ8A 2AB4A 1Q7HA 3HJWA 1PRZA 2APOA 1ZS7A 1WXXA 2I82A 1QYUA 2AS0A 2CWWA 3LWVA 1ZL3A 1R3EA 1R3FA 1IT7A 2J5TA 3DH3A 1SQWA 1XPIA 4LABA 1ZE1A 2AUSA 4Q1TA 1SZWA 4DMGA 1KSVA 1SI7A 1Z2ZA 3C0KA 2P38A 3U28A 3LWRA 2RFKA 4LGTA 2ISTA 1V9KA 2B78A 1WXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSK A;  2EY4 A;  3LWQ A;  3LDF A;  1SGV A;  3VSE A;  1V9F A;  3LWO A;  2Q07 A;  2HVY A;  1ZE2 A;  1K8W A;  1J2B A;  3HJY A;  3MQK A;  3D79 A;  3UAI A;  3LWP A;  2CX1 A;  2J5V A;  3HAX A;  1KSL A;  2CX0 A;  1T5Y A;  1IT8 A;  1IQ8 A;  2AB4 A;  1Q7H A;  3HJW A;  1PRZ A;  2APO A;  1ZS7 A;  1WXX A;  2I82 A;  1QYU A;  2AS0 A;  2CWW A;  3LWV A;  1ZL3 A;  1R3E A;  1R3F A;  1IT7 A;  2J5T A;  3DH3 A;  1SQW A;  1XPI A;  4LAB A;  1ZE1 A;  2AUS A;  4Q1T A;  4DMG A;  1KSV A;  3C0K A;  2P38 A;  3U28 A;  3LWR A;  2RFK A;  4LGT A;  2IST A;  1V9K A;  2B78 A;  1WXW A; 
#chains in the Genus database with same CATH topology
 2EY4 A;  1V9F A;  3LWO A;  3LWP A;  2CX1 A;  3HJW A;  2Z0T A;  3M6V A;  3M65 A;  1TE7 A;  4CI2 B;  1WXX A;  1QYU A;  2CWW A;  3LWV A;  2DP9 A;  4LAB A;  4Q1T A;  4DMG A;  1Z2Z A;  3U28 A;  2P38 A;  2RFK A;  2B78 A;  1S04 A;  3M4X A;  3LWQ A;  1SGV A;  3VSE A;  1K8W A;  3HJY A;  3M6X A;  3D79 A;  2J5V A;  1T5Y A;  1Q7H A;  2FRX A;  2APO A;  1ZS7 A;  3IUW A;  4TZ4 C;  1IT7 A;  2KKU A;  2J5T A;  1SQW A;  3M6W A;  2E5O A;  1ZE1 A;  2AUS A;  3C0K A;  2ANE A;  4LGT A;  2IST A;  1KSK A;  1XNE A;  1ZE2 A;  1J2B A;  3MQK A;  4CI1 B;  1KSL A;  1IT8 A;  1IQ8 A;  1UOY A;  2AS0 A;  1R3E A;  3DH3 A;  1XPI A;  1SZW A;  3LWR A;  3M6U A;  4CI3 B;  3LDF A;  3LJC A;  2HVY A;  2Q07 A;  3UAI A;  3HAX A;  2CX0 A;  1SB7 A;  2AB4 A;  1PRZ A;  3ZV0 C;  2I82 A;  1ZL3 A;  1R3F A;  1ZBO A;  1WK2 A;  1KSV A;  1SI7 A;  1V9K A;  1WXW A; 
#chains in the Genus database with same CATH homology
 1KSK A;  2EY4 A;  3LWQ A;  3LDF A;  1SGV A;  3VSE A;  1V9F A;  3LWO A;  2Q07 A;  2HVY A;  1ZE2 A;  1K8W A;  1J2B A;  3HJY A;  3MQK A;  3D79 A;  3UAI A;  3LWP A;  2CX1 A;  2J5V A;  3HAX A;  1KSL A;  2CX0 A;  1SB7 A;  1T5Y A;  1IT8 A;  1IQ8 A;  2AB4 A;  1Q7H A;  3HJW A;  1PRZ A;  2APO A;  1ZS7 A;  1WXX A;  2I82 A;  1QYU A;  2AS0 A;  2CWW A;  3LWV A;  1ZL3 A;  1R3E A;  1R3F A;  1IT7 A;  2J5T A;  3DH3 A;  1SQW A;  1XPI A;  4LAB A;  1ZE1 A;  2AUS A;  4Q1T A;  1SZW A;  4DMG A;  1KSV A;  1SI7 A;  1Z2Z A;  3C0K A;  2P38 A;  3U28 A;  3LWR A;  2RFK A;  4LGT A;  2IST A;  1V9K A;  2B78 A;  1WXW A; 
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similar chains in the pdb database (?% sequence similarity)

 
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