2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords GLUTAMATE 5-KINASE
publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
3ZZIA 4F6TA 2J0WA 1B7BA 2W21A 2CX0A 2IJ9A 3T7BA 2V4YA 2JI5A 4JZ7A 2BMUA 2BRIA 3D2MA 3S6KA 2Q07A 3K56A 3S6HA 2J4JA 1GS5A 1GSJA 2OGXA 3QVFA 3ZZFA 2B78A 3EK5A 2AB4A 2JJ4A 2RD5A 2WE5A 2BNFA 4NDOA 3S6GA 2P38A 4Q1TA 4A7XA 3AB4A 2AS0A 3KZFA 1ZE1A 3ZZHA 3LL9A 2JJXA 3C1MA 3K4OA 2CX1A 1IT8A 3QURA 1SGVA 1YBDA 3ZZGA 2J4KA 1R3EA 3WWMA 3U6UA 4AXSA 1OHBA 1IQ8A 2BNDA 4I49A 4OLCA 3D2PA 2BUFA 2AP9A 2J5VA 3WWNA 3QUNA 1WXWA 3B8GA 2J5TA 4JZ8A 3D79A 4F6TB 2A1FA 1J2BA 2V5HA 2BNEA 3K4YA 3C20A 2WXBA 3AB2A 3TVIA 3C1NA 2J0XA 2BRXA 4NDRB 4USJA 4KZTA 4NDPB 4AB7A 1ZL3A 1WXXA 2CDQA 4NDQB 3K52A 3D41A 2J4LA 2R8VA 3LKKA 2WE4A 1R3FA 3QUOA 4JZ9A 3LDFA 1SQWA 1ZE2A 1Z9DA 3D40A 2BTYA 3EK6A 2OGXB 2HMFA 1IT7A 3QVHA 3AAWA 3L86A 4NDRA 1T5YA 2CWWA 2VA1A 3C0KA 1K8WA 1Q7HA 4NDOB 4NDPA 2R98A 1OHAA 4A7WA 2AKOA 1OH9A 4NDQA 3NWYA 3LL5A 3VSEA 1ZS7A 2X2WA 3L76A 1E19A 2E9YA 3UAIA 4DMGA
chains in the Genus database with same CATH superfamily
3HJYA 3ZZIA 2J0WA 2APOA 1B7BA 4F6TA 2W21A 2CX0A 2IJ9A 1S04A 3T7BA 2V4YA 2JI5A 4JZ7A 2BMUA 2BRIA 3D2MA 4CI3B 3S6KA 2Q07A 3IUWA 4CI1B 2ANEA 3K56A 3S6HA 2J4JA 1GS5A 1GSJA 2OGXA 3QVFA 3ZZFA 1ZBOA 2B78A 3EK5A 2AB4A 2Z0TA 2JJ4A 2RD5A 2WE5A 4TZ4C 2BNFA 1UOYA 4NDOA 3S6GA 2P38A 4Q1TA 4A7XA 3AB4A 2AS0A 2EY4A 3KZFA 1XNEA 1ZE1A 3ZZHA 3LJCA 3LWRA 3LL9A 2JJXA 3LWPA 3C1MA 3K4OA 2KKUA 2CX1A 1IT8A 3QURA 1SGVA 1YBDA 3ZZGA 2J4KA 1R3EA 3WWMA 3U6UA 4AXSA 1OHBA 1IQ8A 3M6XA 2BNDA 4I49A 4OLCA 3UAIA 3D2PA 2BUFA 2RFKA 2E5OA 2AP9A 2J5VA 3WWNA 3QUNA 1WXWA 3B8GA 2J5TA 4JZ8A 3D79A 4F6TB 2A1FA 1J2BA 2V5HA 2BNEA 3K4YA 3MQKA 3C20A 2WXBA 3AB2A 3TVIA 3M4XA 3C1NA 2J0XA 2BRXA 4NDRB 4USJA 4KZTA 4CI2B 4NDPB 4AB7A 1ZL3A 1WXXA 2CDQA 4NDQB 3K52A 1TE7A 3ZV0C 3D41A 2J4LA 2R8VA 3LKKA 2WE4A 1R3FA 3QUOA 3M6UA 4JZ9A 3M6VA 3HJWA 3M65A 3LWQA 3LDFA 1SQWA 1ZE2A 2HVYA 1Z9DA 3D40A 2BTYA 3LWVA 3EK6A 3HAXA 2OGXB 2HMFA 3U28A 1IT7A 3QVHA 3AAWA 3L86A 4NDRA 1T5YA 2CWWA 2VA1A 3C0KA 1K8WA 1Q7HA 4NDOB 3M6WA 4NDPA 2DP9A 2R98A 1OHAA 4A7WA 2AKOA 1OH9A 4NDQA 3NWYA 3LL5A 3VSEA 1ZS7A 2X2WA 3L76A 1E19A 2AUSA 2FRXA 2E9YA 1WK2A 3LWOA 4DMGA
chains in the Genus database with same CATH topology
3ZZIA 4F6TA 2J0WA 1B7BA 2W21A 2CX0A 2IJ9A 3T7BA 2V4YA 2JI5A 4JZ7A 2BMUA 2BRIA 3D2MA 3S6KA 2Q07A 3K56A 3S6HA 2J4JA 1GS5A 1GSJA 2OGXA 3QVFA 3ZZFA 2B78A 3EK5A 2AB4A 2JJ4A 2RD5A 2WE5A 2BNFA 4NDOA 3S6GA 2P38A 4Q1TA 4A7XA 3AB4A 2AS0A 3KZFA 1ZE1A 3ZZHA 3LL9A 2JJXA 3C1MA 3K4OA 2CX1A 1IT8A 3QURA 1SGVA 1YBDA 3ZZGA 2J4KA 1R3EA 3WWMA 3U6UA 4AXSA 1OHBA 1IQ8A 2BNDA 4I49A 4OLCA 3D2PA 2BUFA 2AP9A 2J5VA 3WWNA 3QUNA 1WXWA 3B8GA 2J5TA 4JZ8A 3D79A 4F6TB 2A1FA 1J2BA 2V5HA 2BNEA 3K4YA 3C20A 2WXBA 3AB2A 3TVIA 3C1NA 2J0XA 2BRXA 4NDRB 4USJA 4KZTA 4NDPB 4AB7A 1ZL3A 1WXXA 2CDQA 4NDQB 3K52A 3D41A 2J4LA 2R8VA 3LKKA 2WE4A 1R3FA 3QUOA 4JZ9A 3LDFA 1SQWA 1ZE2A 1Z9DA 3D40A 2BTYA 3EK6A 2OGXB 2HMFA 1IT7A 3QVHA 3AAWA 3L86A 4NDRA 1T5YA 2CWWA 2VA1A 3C0KA 1K8WA 1Q7HA 4NDOB 4NDPA 2R98A 1OHAA 4A7WA 2AKOA 1OH9A 4NDQA 3NWYA 3LL5A 3VSEA 1ZS7A 2X2WA 3L76A 1E19A 2E9YA 3UAIA 4DMGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZZI A;  4F6T A;  2J0W A;  1B7B A;  2W21 A;  2CX0 A;  2IJ9 A;  3T7B A;  2V4Y A;  2JI5 A;  4JZ7 A;  2BMU A;  2BRI A;  3D2M A;  3S6K A;  2Q07 A;  3K56 A;  3S6H A;  2J4J A;  1GS5 A;  1GSJ A;  2OGX A;  3QVF A;  3ZZF A;  2B78 A;  3EK5 A;  2AB4 A;  2JJ4 A;  2RD5 A;  2WE5 A;  2BNF A;  4NDO A;  3S6G A;  2P38 A;  4Q1T A;  4A7X A;  3AB4 A;  2AS0 A;  3KZF A;  1ZE1 A;  3ZZH A;  3LL9 A;  2JJX A;  3C1M A;  3K4O A;  2CX1 A;  1IT8 A;  3QUR A;  1SGV A;  1YBD A;  3ZZG A;  2J4K A;  1R3E A;  3WWM A;  3U6U A;  4AXS A;  1OHB A;  1IQ8 A;  2BND A;  4I49 A;  4OLC A;  3D2P A;  2BUF A;  2AP9 A;  2J5V A;  3WWN A;  3QUN A;  1WXW A;  3B8G A;  2J5T A;  4JZ8 A;  3D79 A;  4F6T B;  2A1F A;  1J2B A;  2V5H A;  2BNE A;  3K4Y A;  3C20 A;  2WXB A;  3AB2 A;  3TVI A;  3C1N A;  2J0X A;  2BRX A;  4NDR B;  4USJ A;  4KZT A;  4NDP B;  4AB7 A;  1ZL3 A;  1WXX A;  2CDQ A;  4NDQ B;  3K52 A;  3D41 A;  2J4L A;  2R8V A;  3LKK A;  2WE4 A;  1R3F A;  3QUO A;  4JZ9 A;  3LDF A;  1SQW A;  1ZE2 A;  1Z9D A;  3D40 A;  2BTY A;  3EK6 A;  2OGX B;  2HMF A;  1IT7 A;  3QVH A;  3AAW A;  3L86 A;  4NDR A;  1T5Y A;  2CWW A;  2VA1 A;  3C0K A;  1K8W A;  1Q7H A;  4NDO B;  4NDP A;  2R98 A;  1OHA A;  4A7W A;  2AKO A;  1OH9 A;  4NDQ A;  3NWY A;  3LL5 A;  3VSE A;  1ZS7 A;  2X2W A;  3L76 A;  1E19 A;  2E9Y A;  3UAI A;  4DMG A; 
#chains in the Genus database with same CATH topology
 3HJY A;  3ZZI A;  2J0W A;  2APO A;  1B7B A;  4F6T A;  2W21 A;  2CX0 A;  2IJ9 A;  1S04 A;  3T7B A;  2V4Y A;  2JI5 A;  4JZ7 A;  2BMU A;  2BRI A;  3D2M A;  4CI3 B;  3S6K A;  2Q07 A;  3IUW A;  4CI1 B;  2ANE A;  3K56 A;  3S6H A;  2J4J A;  1GS5 A;  1GSJ A;  2OGX A;  3QVF A;  3ZZF A;  1ZBO A;  2B78 A;  3EK5 A;  2AB4 A;  2Z0T A;  2JJ4 A;  2RD5 A;  2WE5 A;  4TZ4 C;  2BNF A;  1UOY A;  4NDO A;  3S6G A;  2P38 A;  4Q1T A;  4A7X A;  3AB4 A;  2AS0 A;  2EY4 A;  3KZF A;  1XNE A;  1ZE1 A;  3ZZH A;  3LJC A;  3LWR A;  3LL9 A;  2JJX A;  3LWP A;  3C1M A;  3K4O A;  2KKU A;  2CX1 A;  1IT8 A;  3QUR A;  1SGV A;  1YBD A;  3ZZG A;  2J4K A;  1R3E A;  3WWM A;  3U6U A;  4AXS A;  1OHB A;  1IQ8 A;  3M6X A;  2BND A;  4I49 A;  4OLC A;  3UAI A;  3D2P A;  2BUF A;  2RFK A;  2E5O A;  2AP9 A;  2J5V A;  3WWN A;  3QUN A;  1WXW A;  3B8G A;  2J5T A;  4JZ8 A;  3D79 A;  4F6T B;  2A1F A;  1J2B A;  2V5H A;  2BNE A;  3K4Y A;  3MQK A;  3C20 A;  2WXB A;  3AB2 A;  3TVI A;  3M4X A;  3C1N A;  2J0X A;  2BRX A;  4NDR B;  4USJ A;  4KZT A;  4CI2 B;  4NDP B;  4AB7 A;  1ZL3 A;  1WXX A;  2CDQ A;  4NDQ B;  3K52 A;  1TE7 A;  3ZV0 C;  3D41 A;  2J4L A;  2R8V A;  3LKK A;  2WE4 A;  1R3F A;  3QUO A;  3M6U A;  4JZ9 A;  3M6V A;  3HJW A;  3M65 A;  3LWQ A;  3LDF A;  1SQW A;  1ZE2 A;  2HVY A;  1Z9D A;  3D40 A;  2BTY A;  3LWV A;  3EK6 A;  3HAX A;  2OGX B;  2HMF A;  3U28 A;  1IT7 A;  3QVH A;  3AAW A;  3L86 A;  4NDR A;  1T5Y A;  2CWW A;  2VA1 A;  3C0K A;  1K8W A;  1Q7H A;  4NDO B;  3M6W A;  4NDP A;  2DP9 A;  2R98 A;  1OHA A;  4A7W A;  2AKO A;  1OH9 A;  4NDQ A;  3NWY A;  3LL5 A;  3VSE A;  1ZS7 A;  2X2W A;  3L76 A;  1E19 A;  2AUS A;  2FRX A;  2E9Y A;  1WK2 A;  3LWO A;  4DMG A; 
#chains in the Genus database with same CATH homology
 3ZZI A;  4F6T A;  2J0W A;  1B7B A;  2W21 A;  2CX0 A;  2IJ9 A;  3T7B A;  2V4Y A;  2JI5 A;  4JZ7 A;  2BMU A;  2BRI A;  3D2M A;  3S6K A;  2Q07 A;  3K56 A;  3S6H A;  2J4J A;  1GS5 A;  1GSJ A;  2OGX A;  3QVF A;  3ZZF A;  2B78 A;  3EK5 A;  2AB4 A;  2JJ4 A;  2RD5 A;  2WE5 A;  2BNF A;  4NDO A;  3S6G A;  2P38 A;  4Q1T A;  4A7X A;  3AB4 A;  2AS0 A;  3KZF A;  1ZE1 A;  3ZZH A;  3LL9 A;  2JJX A;  3C1M A;  3K4O A;  2CX1 A;  1IT8 A;  3QUR A;  1SGV A;  1YBD A;  3ZZG A;  2J4K A;  1R3E A;  3WWM A;  3U6U A;  4AXS A;  1OHB A;  1IQ8 A;  2BND A;  4I49 A;  4OLC A;  3D2P A;  2BUF A;  2AP9 A;  2J5V A;  3WWN A;  3QUN A;  1WXW A;  3B8G A;  2J5T A;  4JZ8 A;  3D79 A;  4F6T B;  2A1F A;  1J2B A;  2V5H A;  2BNE A;  3K4Y A;  3C20 A;  2WXB A;  3AB2 A;  3TVI A;  3C1N A;  2J0X A;  2BRX A;  4NDR B;  4USJ A;  4KZT A;  4NDP B;  4AB7 A;  1ZL3 A;  1WXX A;  2CDQ A;  4NDQ B;  3K52 A;  3D41 A;  2J4L A;  2R8V A;  3LKK A;  2WE4 A;  1R3F A;  3QUO A;  4JZ9 A;  3LDF A;  1SQW A;  1ZE2 A;  1Z9D A;  3D40 A;  2BTY A;  3EK6 A;  2OGX B;  2HMF A;  1IT7 A;  3QVH A;  3AAW A;  3L86 A;  4NDR A;  1T5Y A;  2CWW A;  2VA1 A;  3C0K A;  1K8W A;  1Q7H A;  4NDO B;  4NDP A;  2R98 A;  1OHA A;  4A7W A;  2AKO A;  1OH9 A;  4NDQ A;  3NWY A;  3LL5 A;  3VSE A;  1ZS7 A;  2X2W A;  3L76 A;  1E19 A;  2E9Y A;  3UAI A;  4DMG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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