2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords GLUTAMATE 5-KINASE
publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
2AS0A 3LL9A 2CWWA 3D2PA 1E19A 2Q07A 1ZE2A 3AAWA 3ZZHA 2JJXA 3C0KA 2X2WA 3K4OA 1SGVA 3K52A 4F6TA 2R98A 1IQ8A 3QUNA 4AXSA 3ZZFA 2WXBA 4NDPB 3TVIA 2AKOA 2J4LA 2JI5A 2J4KA 2JJ4A 2A1FA 2CDQA 2BTYA 2W21A 4NDOB 3S6KA 2HMFA 2P38A 2E9YA 4JZ9A 4AB7A 1ZE1A 4Q1TA 4DMGA 3AB4A 1ZS7A 1YBDA 1Q7HA 2OGXB 3L76A 2V5HA 2J5TA 3QVFA 3ZZIA 4OLCA 2BRXA 3QUOA 3K4YA 4NDQB 2VA1A 3NWYA 1R3EA 2BNDA 2IJ9A 2J4JA 3D2MA 4I49A 4NDRA 3AB2A 3K56A 1ZL3A 2RD5A 4F6TB 1GSJA 3S6HA 1K8WA 3T7BA 3WWMA 4USJA 2BMUA 2BNEA 1WXWA 3EK6A 2WE5A 3KZFA 2B78A 1WXXA 4NDOA 1B7BA 3LL5A 2BNFA 2V4YA 3ZZGA 3S6GA 3U6UA 3UAIA 3C1MA 4KZTA 3WWNA 3LKKA 4NDRB 4JZ8A 3B8GA 2WE4A 1T5YA 3LDFA 2BUFA 1GS5A 2AP9A 1OH9A 3D79A 2BRIA 2AB4A 1J2BA 1R3FA 2CX1A 3C20A 4NDPA 3L86A 1IT8A 3QVHA 1SQWA 1OHAA 4A7WA 3C1NA 3D40A 3EK5A 3QURA 2J5VA 3D41A 1OHBA 2R8VA 1Z9DA 2OGXA 4A7XA 4JZ7A 2J0XA 1IT7A 2J0WA 3VSEA 2CX0A 4NDQA
chains in the Genus database with same CATH superfamily
2AS0A 3LL9A 2CWWA 3D2PA 1E19A 2Q07A 1ZE2A 3AAWA 3ZZHA 2JJXA 3C0KA 2Z0TA 2X2WA 3K4OA 1SGVA 3K52A 4F6TA 1S04A 2R98A 1ZBOA 3M6XA 1IQ8A 3QUNA 4AXSA 3ZZFA 2WXBA 4NDPB 3TVIA 1TE7A 2AKOA 2J4LA 2J4KA 2JI5A 2AUSA 3LJCA 2JJ4A 2A1FA 2CDQA 2BTYA 2W21A 4NDOB 3S6KA 3M4XA 2HMFA 2P38A 2E9YA 4JZ9A 4AB7A 1ZE1A 2ANEA 3LWRA 4Q1TA 4DMGA 3AB4A 3MQKA 1ZS7A 1YBDA 3M65A 1Q7HA 4CI2B 2RFKA 2OGXB 3L76A 2V5HA 2J5TA 3QVFA 3ZZIA 4OLCA 2BRXA 3QUOA 3K4YA 4NDQB 3M6VA 2VA1A 3NWYA 1R3EA 2BNDA 3M6WA 2IJ9A 2J4JA 3D2MA 2E5OA 4I49A 4NDRA 3AB2A 2KKUA 3K56A 1ZL3A 3LWPA 3HJWA 2RD5A 3HAXA 4F6TB 1GSJA 3S6HA 1K8WA 1WK2A 3T7BA 3WWMA 4USJA 2BMUA 3IUWA 3M6UA 2BNEA 2APOA 1WXWA 3LWQA 3HJYA 3ZV0C 3EK6A 2WE5A 3KZFA 3LWOA 3U28A 2B78A 1WXXA 4NDOA 1B7BA 1XNEA 3LL5A 2BNFA 2V4YA 3ZZGA 3S6GA 3U6UA 3UAIA 3C1MA 4KZTA 3WWNA 3LKKA 4TZ4C 4NDRB 4JZ8A 3B8GA 2WE4A 1T5YA 3LDFA 2BUFA 1GS5A 2AP9A 1OH9A 3D79A 2BRIA 2AB4A 1J2BA 1R3FA 2CX1A 3C20A 4NDPA 3L86A 1IT8A 3QVHA 3LWVA 2EY4A 1SQWA 2HVYA 1OHAA 4A7WA 3C1NA 3D40A 3EK5A 3QURA 4CI1B 2FRXA 2J5VA 1UOYA 2DP9A 3D41A 1OHBA 2R8VA 1Z9DA 2OGXA 4A7XA 4JZ7A 2J0XA 1IT7A 2J0WA 3VSEA 2CX0A 4CI3B 4NDQA
chains in the Genus database with same CATH topology
2AS0A 3LL9A 2CWWA 3D2PA 1E19A 2Q07A 1ZE2A 3AAWA 3ZZHA 2JJXA 3C0KA 2X2WA 3K4OA 1SGVA 3K52A 4F6TA 2R98A 1IQ8A 3QUNA 4AXSA 3ZZFA 2WXBA 4NDPB 3TVIA 2AKOA 2J4LA 2JI5A 2J4KA 2JJ4A 2A1FA 2CDQA 2BTYA 2W21A 4NDOB 3S6KA 2HMFA 2P38A 2E9YA 4JZ9A 4AB7A 1ZE1A 4Q1TA 4DMGA 3AB4A 1ZS7A 1YBDA 1Q7HA 2OGXB 3L76A 2V5HA 2J5TA 3QVFA 3ZZIA 4OLCA 2BRXA 3QUOA 3K4YA 4NDQB 2VA1A 3NWYA 1R3EA 2BNDA 2IJ9A 2J4JA 3D2MA 4I49A 4NDRA 3AB2A 3K56A 1ZL3A 2RD5A 4F6TB 1GSJA 3S6HA 1K8WA 3T7BA 3WWMA 4USJA 2BMUA 2BNEA 1WXWA 3EK6A 2WE5A 3KZFA 2B78A 1WXXA 4NDOA 1B7BA 3LL5A 2BNFA 2V4YA 3ZZGA 3S6GA 3U6UA 3UAIA 3C1MA 4KZTA 3WWNA 3LKKA 4NDRB 4JZ8A 3B8GA 2WE4A 1T5YA 3LDFA 2BUFA 1GS5A 2AP9A 1OH9A 3D79A 2BRIA 2AB4A 1J2BA 1R3FA 2CX1A 3C20A 4NDPA 3L86A 1IT8A 3QVHA 1SQWA 1OHAA 4A7WA 3C1NA 3D40A 3EK5A 3QURA 2J5VA 3D41A 1OHBA 2R8VA 1Z9DA 2OGXA 4A7XA 4JZ7A 2J0XA 1IT7A 2J0WA 3VSEA 2CX0A 4NDQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AS0 A;  3LL9 A;  2CWW A;  3D2P A;  1E19 A;  2Q07 A;  1ZE2 A;  3AAW A;  3ZZH A;  2JJX A;  3C0K A;  2X2W A;  3K4O A;  1SGV A;  3K52 A;  4F6T A;  2R98 A;  1IQ8 A;  3QUN A;  4AXS A;  3ZZF A;  2WXB A;  4NDP B;  3TVI A;  2AKO A;  2J4L A;  2JI5 A;  2J4K A;  2JJ4 A;  2A1F A;  2CDQ A;  2BTY A;  2W21 A;  4NDO B;  3S6K A;  2HMF A;  2P38 A;  2E9Y A;  4JZ9 A;  4AB7 A;  1ZE1 A;  4Q1T A;  4DMG A;  3AB4 A;  1ZS7 A;  1YBD A;  1Q7H A;  2OGX B;  3L76 A;  2V5H A;  2J5T A;  3QVF A;  3ZZI A;  4OLC A;  2BRX A;  3QUO A;  3K4Y A;  4NDQ B;  2VA1 A;  3NWY A;  1R3E A;  2BND A;  2IJ9 A;  2J4J A;  3D2M A;  4I49 A;  4NDR A;  3AB2 A;  3K56 A;  1ZL3 A;  2RD5 A;  4F6T B;  1GSJ A;  3S6H A;  1K8W A;  3T7B A;  3WWM A;  4USJ A;  2BMU A;  2BNE A;  1WXW A;  3EK6 A;  2WE5 A;  3KZF A;  2B78 A;  1WXX A;  4NDO A;  1B7B A;  3LL5 A;  2BNF A;  2V4Y A;  3ZZG A;  3S6G A;  3U6U A;  3UAI A;  3C1M A;  4KZT A;  3WWN A;  3LKK A;  4NDR B;  4JZ8 A;  3B8G A;  2WE4 A;  1T5Y A;  3LDF A;  2BUF A;  1GS5 A;  2AP9 A;  1OH9 A;  3D79 A;  2BRI A;  2AB4 A;  1J2B A;  1R3F A;  2CX1 A;  3C20 A;  4NDP A;  3L86 A;  1IT8 A;  3QVH A;  1SQW A;  1OHA A;  4A7W A;  3C1N A;  3D40 A;  3EK5 A;  3QUR A;  2J5V A;  3D41 A;  1OHB A;  2R8V A;  1Z9D A;  2OGX A;  4A7X A;  4JZ7 A;  2J0X A;  1IT7 A;  2J0W A;  3VSE A;  2CX0 A;  4NDQ A; 
#chains in the Genus database with same CATH topology
 2AS0 A;  3LL9 A;  2CWW A;  3D2P A;  1E19 A;  2Q07 A;  1ZE2 A;  3AAW A;  3ZZH A;  2JJX A;  3C0K A;  2Z0T A;  2X2W A;  3K4O A;  1SGV A;  3K52 A;  4F6T A;  1S04 A;  2R98 A;  1ZBO A;  3M6X A;  1IQ8 A;  3QUN A;  4AXS A;  3ZZF A;  2WXB A;  4NDP B;  3TVI A;  1TE7 A;  2AKO A;  2J4L A;  2J4K A;  2JI5 A;  2AUS A;  3LJC A;  2JJ4 A;  2A1F A;  2CDQ A;  2BTY A;  2W21 A;  4NDO B;  3S6K A;  3M4X A;  2HMF A;  2P38 A;  2E9Y A;  4JZ9 A;  4AB7 A;  1ZE1 A;  2ANE A;  3LWR A;  4Q1T A;  4DMG A;  3AB4 A;  3MQK A;  1ZS7 A;  1YBD A;  3M65 A;  1Q7H A;  4CI2 B;  2RFK A;  2OGX B;  3L76 A;  2V5H A;  2J5T A;  3QVF A;  3ZZI A;  4OLC A;  2BRX A;  3QUO A;  3K4Y A;  4NDQ B;  3M6V A;  2VA1 A;  3NWY A;  1R3E A;  2BND A;  3M6W A;  2IJ9 A;  2J4J A;  3D2M A;  2E5O A;  4I49 A;  4NDR A;  3AB2 A;  2KKU A;  3K56 A;  1ZL3 A;  3LWP A;  3HJW A;  2RD5 A;  3HAX A;  4F6T B;  1GSJ A;  3S6H A;  1K8W A;  1WK2 A;  3T7B A;  3WWM A;  4USJ A;  2BMU A;  3IUW A;  3M6U A;  2BNE A;  2APO A;  1WXW A;  3LWQ A;  3HJY A;  3ZV0 C;  3EK6 A;  2WE5 A;  3KZF A;  3LWO A;  3U28 A;  2B78 A;  1WXX A;  4NDO A;  1B7B A;  1XNE A;  3LL5 A;  2BNF A;  2V4Y A;  3ZZG A;  3S6G A;  3U6U A;  3UAI A;  3C1M A;  4KZT A;  3WWN A;  3LKK A;  4TZ4 C;  4NDR B;  4JZ8 A;  3B8G A;  2WE4 A;  1T5Y A;  3LDF A;  2BUF A;  1GS5 A;  2AP9 A;  1OH9 A;  3D79 A;  2BRI A;  2AB4 A;  1J2B A;  1R3F A;  2CX1 A;  3C20 A;  4NDP A;  3L86 A;  1IT8 A;  3QVH A;  3LWV A;  2EY4 A;  1SQW A;  2HVY A;  1OHA A;  4A7W A;  3C1N A;  3D40 A;  3EK5 A;  3QUR A;  4CI1 B;  2FRX A;  2J5V A;  1UOY A;  2DP9 A;  3D41 A;  1OHB A;  2R8V A;  1Z9D A;  2OGX A;  4A7X A;  4JZ7 A;  2J0X A;  1IT7 A;  2J0W A;  3VSE A;  2CX0 A;  4CI3 B;  4NDQ A; 
#chains in the Genus database with same CATH homology
 2AS0 A;  3LL9 A;  2CWW A;  3D2P A;  1E19 A;  2Q07 A;  1ZE2 A;  3AAW A;  3ZZH A;  2JJX A;  3C0K A;  2X2W A;  3K4O A;  1SGV A;  3K52 A;  4F6T A;  2R98 A;  1IQ8 A;  3QUN A;  4AXS A;  3ZZF A;  2WXB A;  4NDP B;  3TVI A;  2AKO A;  2J4L A;  2JI5 A;  2J4K A;  2JJ4 A;  2A1F A;  2CDQ A;  2BTY A;  2W21 A;  4NDO B;  3S6K A;  2HMF A;  2P38 A;  2E9Y A;  4JZ9 A;  4AB7 A;  1ZE1 A;  4Q1T A;  4DMG A;  3AB4 A;  1ZS7 A;  1YBD A;  1Q7H A;  2OGX B;  3L76 A;  2V5H A;  2J5T A;  3QVF A;  3ZZI A;  4OLC A;  2BRX A;  3QUO A;  3K4Y A;  4NDQ B;  2VA1 A;  3NWY A;  1R3E A;  2BND A;  2IJ9 A;  2J4J A;  3D2M A;  4I49 A;  4NDR A;  3AB2 A;  3K56 A;  1ZL3 A;  2RD5 A;  4F6T B;  1GSJ A;  3S6H A;  1K8W A;  3T7B A;  3WWM A;  4USJ A;  2BMU A;  2BNE A;  1WXW A;  3EK6 A;  2WE5 A;  3KZF A;  2B78 A;  1WXX A;  4NDO A;  1B7B A;  3LL5 A;  2BNF A;  2V4Y A;  3ZZG A;  3S6G A;  3U6U A;  3UAI A;  3C1M A;  4KZT A;  3WWN A;  3LKK A;  4NDR B;  4JZ8 A;  3B8G A;  2WE4 A;  1T5Y A;  3LDF A;  2BUF A;  1GS5 A;  2AP9 A;  1OH9 A;  3D79 A;  2BRI A;  2AB4 A;  1J2B A;  1R3F A;  2CX1 A;  3C20 A;  4NDP A;  3L86 A;  1IT8 A;  3QVH A;  1SQW A;  1OHA A;  4A7W A;  3C1N A;  3D40 A;  3EK5 A;  3QUR A;  2J5V A;  3D41 A;  1OHB A;  2R8V A;  1Z9D A;  2OGX A;  4A7X A;  4JZ7 A;  2J0X A;  1IT7 A;  2J0W A;  3VSE A;  2CX0 A;  4NDQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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