2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords GLUTAMATE 5-KINASE
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
2V4YA 3C0KA 4NDRB 1B7BA 2JI5A 2CWWA 2WE5A 3C20A 4NDPB 3AB2A 4Q1TA 4OLCA 1OH9A 1Q7HA 3WWMA 2BNFA 3ZZFA 3B8GA 2WXBA 1R3EA 3EK6A 1ZE1A 3S6HA 2OGXA 4NDQB 1E19A 3C1MA 3NWYA 4NDOA 3LDFA 2J4KA 4F6TA 4JZ9A 3VSEA 3EK5A 2BUFA 2J0XA 3S6GA 1GS5A 3K52A 1WXXA 3L86A 3K56A 2E9YA 3QUNA 4A7XA 2CX1A 2BTYA 2VA1A 2J5TA 3LKKA 1SGVA 2J5VA 2CX0A 4KZTA 1WXWA 3QVFA 2BMUA 2AB4A 2W21A 1OHBA 2J4LA 3TVIA 3UAIA 1T5YA 1J2BA 3D41A 1IQ8A 1SQWA 1ZE2A 3K4YA 3LL9A 3WWNA 1GSJA 4F6TB 3QVHA 4USJA 3QUOA 2RD5A 2CDQA 4AB7A 2OGXB 1ZL3A 2P38A 2B78A 1IT8A 3C1NA 1Z9DA 2Q07A 1OHAA 3D40A 2BRIA 3K4OA 1YBDA 3T7BA 2R98A 4A7WA 2V5HA 2J0WA 1R3FA 2R8VA 2AP9A 4NDPA 2AS0A 2BNEA 4JZ7A 2X2WA 3ZZIA 2J4JA 3D79A 2A1FA 2JJXA 1K8WA 3L76A 3AB4A 2HMFA 4NDQA 3D2MA 1ZS7A 3KZFA 3AAWA 3ZZHA 2AKOA 2BNDA 4I49A 3ZZGA 4NDOB 2IJ9A 2JJ4A 4DMGA 2BRXA 3LL5A 3D2PA 4JZ8A 4AXSA 4NDRA 1IT7A 3S6KA 3U6UA 3QURA 2WE4A
chains in the Genus database with same CATH superfamily
2V4YA 3C0KA 4NDRB 1B7BA 2JI5A 2CWWA 2WE5A 3C20A 4NDPB 3AB2A 4Q1TA 4OLCA 1OH9A 1Q7HA 3WWMA 2E5OA 2BNFA 3LWPA 3ZZFA 3B8GA 2WXBA 1R3EA 3EK6A 1ZE1A 3S6HA 3M6UA 2OGXA 3LWOA 4NDQB 1E19A 3C1MA 2ANEA 3NWYA 3HAXA 4CI2B 4NDOA 3LDFA 3M65A 3LWRA 2J4KA 4F6TA 4JZ9A 3VSEA 3EK5A 2BUFA 2J0XA 3S6GA 1GS5A 3LWQA 3K52A 1WXXA 2APOA 3L86A 3K56A 2E9YA 3QUNA 4A7XA 2EY4A 2CX1A 2RFKA 2BTYA 2VA1A 2J5TA 3LKKA 1SGVA 2J5VA 3M6XA 2CX0A 4KZTA 1WXWA 3QVFA 2BMUA 2AB4A 2KKUA 2W21A 1OHBA 2J4LA 3TVIA 1S04A 3M4XA 3UAIA 3HJYA 1T5YA 1J2BA 3LJCA 3D41A 1ZBOA 1IQ8A 3IUWA 1SQWA 1ZE2A 3K4YA 3LL9A 3WWNA 1GSJA 4F6TB 3QVHA 4USJA 3QUOA 2RD5A 2CDQA 4AB7A 1UOYA 2OGXB 1ZL3A 2P38A 2B78A 3MQKA 2AUSA 1IT8A 3C1NA 1Z9DA 2Q07A 1OHAA 3D40A 2BRIA 4TZ4C 3K4OA 1YBDA 3T7BA 2R98A 2DP9A 1XNEA 4A7WA 2V5HA 2J0WA 1R3FA 2R8VA 2AP9A 4NDPA 2AS0A 3M6VA 2BNEA 2X2WA 4JZ7A 3ZZIA 2J4JA 3D79A 2A1FA 2JJXA 1K8WA 3L76A 4CI3B 3HJWA 2HMFA 3AB4A 4NDQA 3D2MA 1ZS7A 3KZFA 2FRXA 3AAWA 1TE7A 2Z0TA 3ZZHA 2AKOA 3M6WA 2BNDA 4I49A 3ZZGA 4NDOB 3ZV0C 3U28A 2IJ9A 2JJ4A 4DMGA 2BRXA 3LL5A 2HVYA 1WK2A 3D2PA 4JZ8A 4AXSA 4NDRA 1IT7A 3S6KA 4CI1B 3U6UA 3LWVA 3QURA 2WE4A
chains in the Genus database with same CATH topology
2V4YA 3C0KA 4NDRB 1B7BA 2JI5A 2CWWA 2WE5A 3C20A 4NDPB 3AB2A 4Q1TA 4OLCA 1OH9A 1Q7HA 3WWMA 2BNFA 3ZZFA 3B8GA 2WXBA 1R3EA 3EK6A 1ZE1A 3S6HA 2OGXA 4NDQB 1E19A 3C1MA 3NWYA 4NDOA 3LDFA 2J4KA 4F6TA 4JZ9A 3VSEA 3EK5A 2BUFA 2J0XA 3S6GA 1GS5A 3K52A 1WXXA 3L86A 3K56A 2E9YA 3QUNA 4A7XA 2CX1A 2BTYA 2VA1A 2J5TA 3LKKA 1SGVA 2J5VA 2CX0A 4KZTA 1WXWA 3QVFA 2BMUA 2AB4A 2W21A 1OHBA 2J4LA 3TVIA 3UAIA 1T5YA 1J2BA 3D41A 1IQ8A 1SQWA 1ZE2A 3K4YA 3LL9A 3WWNA 1GSJA 4F6TB 3QVHA 4USJA 3QUOA 2RD5A 2CDQA 4AB7A 2OGXB 1ZL3A 2P38A 2B78A 1IT8A 3C1NA 1Z9DA 2Q07A 1OHAA 3D40A 2BRIA 3K4OA 1YBDA 3T7BA 2R98A 4A7WA 2V5HA 2J0WA 1R3FA 2R8VA 2AP9A 4NDPA 2AS0A 2BNEA 4JZ7A 2X2WA 3ZZIA 2J4JA 3D79A 2A1FA 2JJXA 1K8WA 3L76A 3AB4A 2HMFA 4NDQA 3D2MA 1ZS7A 3KZFA 3AAWA 3ZZHA 2AKOA 2BNDA 4I49A 3ZZGA 4NDOB 2IJ9A 2JJ4A 4DMGA 2BRXA 3LL5A 3D2PA 4JZ8A 4AXSA 4NDRA 1IT7A 3S6KA 3U6UA 3QURA 2WE4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V4Y A;  3C0K A;  4NDR B;  1B7B A;  2JI5 A;  2CWW A;  2WE5 A;  3C20 A;  4NDP B;  3AB2 A;  4Q1T A;  4OLC A;  1OH9 A;  1Q7H A;  3WWM A;  2BNF A;  3ZZF A;  3B8G A;  2WXB A;  1R3E A;  3EK6 A;  1ZE1 A;  3S6H A;  2OGX A;  4NDQ B;  1E19 A;  3C1M A;  3NWY A;  4NDO A;  3LDF A;  2J4K A;  4F6T A;  4JZ9 A;  3VSE A;  3EK5 A;  2BUF A;  2J0X A;  3S6G A;  1GS5 A;  3K52 A;  1WXX A;  3L86 A;  3K56 A;  2E9Y A;  3QUN A;  4A7X A;  2CX1 A;  2BTY A;  2VA1 A;  2J5T A;  3LKK A;  1SGV A;  2J5V A;  2CX0 A;  4KZT A;  1WXW A;  3QVF A;  2BMU A;  2AB4 A;  2W21 A;  1OHB A;  2J4L A;  3TVI A;  3UAI A;  1T5Y A;  1J2B A;  3D41 A;  1IQ8 A;  1SQW A;  1ZE2 A;  3K4Y A;  3LL9 A;  3WWN A;  1GSJ A;  4F6T B;  3QVH A;  4USJ A;  3QUO A;  2RD5 A;  2CDQ A;  4AB7 A;  2OGX B;  1ZL3 A;  2P38 A;  2B78 A;  1IT8 A;  3C1N A;  1Z9D A;  2Q07 A;  1OHA A;  3D40 A;  2BRI A;  3K4O A;  1YBD A;  3T7B A;  2R98 A;  4A7W A;  2V5H A;  2J0W A;  1R3F A;  2R8V A;  2AP9 A;  4NDP A;  2AS0 A;  2BNE A;  4JZ7 A;  2X2W A;  3ZZI A;  2J4J A;  3D79 A;  2A1F A;  2JJX A;  1K8W A;  3L76 A;  3AB4 A;  2HMF A;  4NDQ A;  3D2M A;  1ZS7 A;  3KZF A;  3AAW A;  3ZZH A;  2AKO A;  2BND A;  4I49 A;  3ZZG A;  4NDO B;  2IJ9 A;  2JJ4 A;  4DMG A;  2BRX A;  3LL5 A;  3D2P A;  4JZ8 A;  4AXS A;  4NDR A;  1IT7 A;  3S6K A;  3U6U A;  3QUR A;  2WE4 A; 
#chains in the Genus database with same CATH topology
 2V4Y A;  3C0K A;  4NDR B;  1B7B A;  2JI5 A;  2CWW A;  2WE5 A;  3C20 A;  4NDP B;  3AB2 A;  4Q1T A;  4OLC A;  1OH9 A;  1Q7H A;  3WWM A;  2E5O A;  2BNF A;  3LWP A;  3ZZF A;  3B8G A;  2WXB A;  1R3E A;  3EK6 A;  1ZE1 A;  3S6H A;  3M6U A;  2OGX A;  3LWO A;  4NDQ B;  1E19 A;  3C1M A;  2ANE A;  3NWY A;  3HAX A;  4CI2 B;  4NDO A;  3LDF A;  3M65 A;  3LWR A;  2J4K A;  4F6T A;  4JZ9 A;  3VSE A;  3EK5 A;  2BUF A;  2J0X A;  3S6G A;  1GS5 A;  3LWQ A;  3K52 A;  1WXX A;  2APO A;  3L86 A;  3K56 A;  2E9Y A;  3QUN A;  4A7X A;  2EY4 A;  2CX1 A;  2RFK A;  2BTY A;  2VA1 A;  2J5T A;  3LKK A;  1SGV A;  2J5V A;  3M6X A;  2CX0 A;  4KZT A;  1WXW A;  3QVF A;  2BMU A;  2AB4 A;  2KKU A;  2W21 A;  1OHB A;  2J4L A;  3TVI A;  1S04 A;  3M4X A;  3UAI A;  3HJY A;  1T5Y A;  1J2B A;  3LJC A;  3D41 A;  1ZBO A;  1IQ8 A;  3IUW A;  1SQW A;  1ZE2 A;  3K4Y A;  3LL9 A;  3WWN A;  1GSJ A;  4F6T B;  3QVH A;  4USJ A;  3QUO A;  2RD5 A;  2CDQ A;  4AB7 A;  1UOY A;  2OGX B;  1ZL3 A;  2P38 A;  2B78 A;  3MQK A;  2AUS A;  1IT8 A;  3C1N A;  1Z9D A;  2Q07 A;  1OHA A;  3D40 A;  2BRI A;  4TZ4 C;  3K4O A;  1YBD A;  3T7B A;  2R98 A;  2DP9 A;  1XNE A;  4A7W A;  2V5H A;  2J0W A;  1R3F A;  2R8V A;  2AP9 A;  4NDP A;  2AS0 A;  3M6V A;  2BNE A;  2X2W A;  4JZ7 A;  3ZZI A;  2J4J A;  3D79 A;  2A1F A;  2JJX A;  1K8W A;  3L76 A;  4CI3 B;  3HJW A;  2HMF A;  3AB4 A;  4NDQ A;  3D2M A;  1ZS7 A;  3KZF A;  2FRX A;  3AAW A;  1TE7 A;  2Z0T A;  3ZZH A;  2AKO A;  3M6W A;  2BND A;  4I49 A;  3ZZG A;  4NDO B;  3ZV0 C;  3U28 A;  2IJ9 A;  2JJ4 A;  4DMG A;  2BRX A;  3LL5 A;  2HVY A;  1WK2 A;  3D2P A;  4JZ8 A;  4AXS A;  4NDR A;  1IT7 A;  3S6K A;  4CI1 B;  3U6U A;  3LWV A;  3QUR A;  2WE4 A; 
#chains in the Genus database with same CATH homology
 2V4Y A;  3C0K A;  4NDR B;  1B7B A;  2JI5 A;  2CWW A;  2WE5 A;  3C20 A;  4NDP B;  3AB2 A;  4Q1T A;  4OLC A;  1OH9 A;  1Q7H A;  3WWM A;  2BNF A;  3ZZF A;  3B8G A;  2WXB A;  1R3E A;  3EK6 A;  1ZE1 A;  3S6H A;  2OGX A;  4NDQ B;  1E19 A;  3C1M A;  3NWY A;  4NDO A;  3LDF A;  2J4K A;  4F6T A;  4JZ9 A;  3VSE A;  3EK5 A;  2BUF A;  2J0X A;  3S6G A;  1GS5 A;  3K52 A;  1WXX A;  3L86 A;  3K56 A;  2E9Y A;  3QUN A;  4A7X A;  2CX1 A;  2BTY A;  2VA1 A;  2J5T A;  3LKK A;  1SGV A;  2J5V A;  2CX0 A;  4KZT A;  1WXW A;  3QVF A;  2BMU A;  2AB4 A;  2W21 A;  1OHB A;  2J4L A;  3TVI A;  3UAI A;  1T5Y A;  1J2B A;  3D41 A;  1IQ8 A;  1SQW A;  1ZE2 A;  3K4Y A;  3LL9 A;  3WWN A;  1GSJ A;  4F6T B;  3QVH A;  4USJ A;  3QUO A;  2RD5 A;  2CDQ A;  4AB7 A;  2OGX B;  1ZL3 A;  2P38 A;  2B78 A;  1IT8 A;  3C1N A;  1Z9D A;  2Q07 A;  1OHA A;  3D40 A;  2BRI A;  3K4O A;  1YBD A;  3T7B A;  2R98 A;  4A7W A;  2V5H A;  2J0W A;  1R3F A;  2R8V A;  2AP9 A;  4NDP A;  2AS0 A;  2BNE A;  4JZ7 A;  2X2W A;  3ZZI A;  2J4J A;  3D79 A;  2A1F A;  2JJX A;  1K8W A;  3L76 A;  3AB4 A;  2HMF A;  4NDQ A;  3D2M A;  1ZS7 A;  3KZF A;  3AAW A;  3ZZH A;  2AKO A;  2BND A;  4I49 A;  3ZZG A;  4NDO B;  2IJ9 A;  2JJ4 A;  4DMG A;  2BRX A;  3LL5 A;  3D2P A;  4JZ8 A;  4AXS A;  4NDR A;  1IT7 A;  3S6K A;  3U6U A;  3QUR A;  2WE4 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...