2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords GLUTAMATE 5-KINASE
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
2V4YA 3S6HA 3UAIA 3C20A 4F6TB 4JZ9A 4NDPB 2CX1A 3C0KA 2BRXA 1OHBA 4I49A 2J0WA 3NWYA 4A7WA 3TVIA 2R98A 1ZE1A 3KZFA 3QUOA 3B8GA 3D41A 3AAWA 2AB4A 2BNFA 3ZZGA 2CWWA 1Z9DA 4JZ8A 3ZZIA 2BTYA 1SQWA 2J0XA 1ZL3A 1Q7HA 1E19A 1WXWA 3C1MA 3T7BA 1B7BA 2V5HA 4A7XA 2WE5A 4NDPA 4NDRB 2OGXA 3QUNA 2WE4A 2OGXB 1GSJA 3QVHA 3AB2A 3EK5A 2B78A 3K52A 3WWMA 1WXXA 3VSEA 4DMGA 1R3FA 3LL5A 1J2BA 1IT8A 3D40A 3ZZFA 3S6KA 2J4JA 4NDRA 2WXBA 1R3EA 4USJA 1ZE2A 1GS5A 4AB7A 4JZ7A 3K56A 3WWNA 1K8WA 3LL9A 1SGVA 1OHAA 4NDOA 2BMUA 1T5YA 4NDOB 3AB4A 2BUFA 3K4OA 2BRIA 4Q1TA 4KZTA 4F6TA 1ZS7A 3L76A 3QVFA 3D2MA 3QURA 2JI5A 2J4KA 1YBDA 2CX0A 3LKKA 3D79A 2JJ4A 2AP9A 2R8VA 4AXSA 4NDQA 2E9YA 2P38A 2J5VA 1OH9A 2W21A 2BNEA 2JJXA 1IQ8A 4NDQB 4OLCA 2IJ9A 3K4YA 2A1FA 2J4LA 2RD5A 3D2PA 2Q07A 2AKOA 3S6GA 2X2WA 2AS0A 3L86A 2J5TA 1IT7A 3LDFA 3C1NA 3EK6A 3U6UA 3ZZHA 2VA1A 2HMFA 2CDQA 2BNDA
chains in the Genus database with same CATH superfamily
2V4YA 3S6HA 3UAIA 3C20A 4F6TB 4JZ9A 4NDPB 3LJCA 2CX1A 3C0KA 2BRXA 1WK2A 1OHBA 4I49A 2ANEA 2J0WA 3NWYA 4A7WA 2Z0TA 3TVIA 2R98A 1ZE1A 3KZFA 2EY4A 3QUOA 3B8GA 3D41A 3AAWA 2AB4A 2BNFA 3ZZGA 2CWWA 1Z9DA 4JZ8A 3ZZIA 2BTYA 1SQWA 2J0XA 1ZL3A 1Q7HA 1E19A 1WXWA 3C1MA 3ZV0C 1B7BA 2V5HA 3T7BA 4A7XA 2WE5A 4NDPA 4NDRB 2OGXA 1ZBOA 3QUNA 2WE4A 2OGXB 1GSJA 3QVHA 3AB2A 3HJWA 3EK5A 3M6UA 2RFKA 2B78A 3K52A 3WWMA 1WXXA 3VSEA 4DMGA 1R3FA 3LL5A 1J2BA 1IT8A 3D40A 3ZZFA 3S6KA 2J4JA 4NDRA 2WXBA 3IUWA 4CI1B 2KKUA 3LWQA 1R3EA 4USJA 3MQKA 1ZE2A 1GS5A 4AB7A 1UOYA 4JZ7A 3K56A 3WWNA 1K8WA 3M4XA 2FRXA 3LL9A 1SGVA 1OHAA 4NDOA 2BMUA 1T5YA 4NDOB 3M6WA 2DP9A 2HVYA 2BUFA 3AB4A 3K4OA 2BRIA 3LWOA 4Q1TA 4KZTA 4F6TA 4CI3B 1ZS7A 3L76A 3QVFA 1XNEA 3D2MA 3QURA 3M6XA 2JI5A 3HAXA 2J4KA 1TE7A 1YBDA 2CX0A 3LKKA 3D79A 3U28A 2JJ4A 2AP9A 2R8VA 2APOA 4TZ4C 3HJYA 4AXSA 1S04A 4NDQA 2E9YA 2P38A 2J5VA 1OH9A 2W21A 2BNEA 2JJXA 2AUSA 3M6VA 1IQ8A 4NDQB 4OLCA 3M65A 2IJ9A 3K4YA 2A1FA 3LWVA 2E5OA 2J4LA 2RD5A 3D2PA 2Q07A 2AKOA 3S6GA 2X2WA 3LWPA 2AS0A 3L86A 2J5TA 1IT7A 3LDFA 3C1NA 3EK6A 3U6UA 3LWRA 3ZZHA 2VA1A 2HMFA 2CDQA 2BNDA 4CI2B
chains in the Genus database with same CATH topology
2V4YA 3S6HA 3UAIA 3C20A 4F6TB 4JZ9A 4NDPB 2CX1A 3C0KA 2BRXA 1OHBA 4I49A 2J0WA 3NWYA 4A7WA 3TVIA 2R98A 1ZE1A 3KZFA 3QUOA 3B8GA 3D41A 3AAWA 2AB4A 2BNFA 3ZZGA 2CWWA 1Z9DA 4JZ8A 3ZZIA 2BTYA 1SQWA 2J0XA 1ZL3A 1Q7HA 1E19A 1WXWA 3C1MA 3T7BA 1B7BA 2V5HA 4A7XA 2WE5A 4NDPA 4NDRB 2OGXA 3QUNA 2WE4A 2OGXB 1GSJA 3QVHA 3AB2A 3EK5A 2B78A 3K52A 3WWMA 1WXXA 3VSEA 4DMGA 1R3FA 3LL5A 1J2BA 1IT8A 3D40A 3ZZFA 3S6KA 2J4JA 4NDRA 2WXBA 1R3EA 4USJA 1ZE2A 1GS5A 4AB7A 4JZ7A 3K56A 3WWNA 1K8WA 3LL9A 1SGVA 1OHAA 4NDOA 2BMUA 1T5YA 4NDOB 3AB4A 2BUFA 3K4OA 2BRIA 4Q1TA 4KZTA 4F6TA 1ZS7A 3L76A 3QVFA 3D2MA 3QURA 2JI5A 2J4KA 1YBDA 2CX0A 3LKKA 3D79A 2JJ4A 2AP9A 2R8VA 4AXSA 4NDQA 2E9YA 2P38A 2J5VA 1OH9A 2W21A 2BNEA 2JJXA 1IQ8A 4NDQB 4OLCA 2IJ9A 3K4YA 2A1FA 2J4LA 2RD5A 3D2PA 2Q07A 2AKOA 3S6GA 2X2WA 2AS0A 3L86A 2J5TA 1IT7A 3LDFA 3C1NA 3EK6A 3U6UA 3ZZHA 2VA1A 2HMFA 2CDQA 2BNDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V4Y A;  3S6H A;  3UAI A;  3C20 A;  4F6T B;  4JZ9 A;  4NDP B;  2CX1 A;  3C0K A;  2BRX A;  1OHB A;  4I49 A;  2J0W A;  3NWY A;  4A7W A;  3TVI A;  2R98 A;  1ZE1 A;  3KZF A;  3QUO A;  3B8G A;  3D41 A;  3AAW A;  2AB4 A;  2BNF A;  3ZZG A;  2CWW A;  1Z9D A;  4JZ8 A;  3ZZI A;  2BTY A;  1SQW A;  2J0X A;  1ZL3 A;  1Q7H A;  1E19 A;  1WXW A;  3C1M A;  3T7B A;  1B7B A;  2V5H A;  4A7X A;  2WE5 A;  4NDP A;  4NDR B;  2OGX A;  3QUN A;  2WE4 A;  2OGX B;  1GSJ A;  3QVH A;  3AB2 A;  3EK5 A;  2B78 A;  3K52 A;  3WWM A;  1WXX A;  3VSE A;  4DMG A;  1R3F A;  3LL5 A;  1J2B A;  1IT8 A;  3D40 A;  3ZZF A;  3S6K A;  2J4J A;  4NDR A;  2WXB A;  1R3E A;  4USJ A;  1ZE2 A;  1GS5 A;  4AB7 A;  4JZ7 A;  3K56 A;  3WWN A;  1K8W A;  3LL9 A;  1SGV A;  1OHA A;  4NDO A;  2BMU A;  1T5Y A;  4NDO B;  3AB4 A;  2BUF A;  3K4O A;  2BRI A;  4Q1T A;  4KZT A;  4F6T A;  1ZS7 A;  3L76 A;  3QVF A;  3D2M A;  3QUR A;  2JI5 A;  2J4K A;  1YBD A;  2CX0 A;  3LKK A;  3D79 A;  2JJ4 A;  2AP9 A;  2R8V A;  4AXS A;  4NDQ A;  2E9Y A;  2P38 A;  2J5V A;  1OH9 A;  2W21 A;  2BNE A;  2JJX A;  1IQ8 A;  4NDQ B;  4OLC A;  2IJ9 A;  3K4Y A;  2A1F A;  2J4L A;  2RD5 A;  3D2P A;  2Q07 A;  2AKO A;  3S6G A;  2X2W A;  2AS0 A;  3L86 A;  2J5T A;  1IT7 A;  3LDF A;  3C1N A;  3EK6 A;  3U6U A;  3ZZH A;  2VA1 A;  2HMF A;  2CDQ A;  2BND A; 
#chains in the Genus database with same CATH topology
 2V4Y A;  3S6H A;  3UAI A;  3C20 A;  4F6T B;  4JZ9 A;  4NDP B;  3LJC A;  2CX1 A;  3C0K A;  2BRX A;  1WK2 A;  1OHB A;  4I49 A;  2ANE A;  2J0W A;  3NWY A;  4A7W A;  2Z0T A;  3TVI A;  2R98 A;  1ZE1 A;  3KZF A;  2EY4 A;  3QUO A;  3B8G A;  3D41 A;  3AAW A;  2AB4 A;  2BNF A;  3ZZG A;  2CWW A;  1Z9D A;  4JZ8 A;  3ZZI A;  2BTY A;  1SQW A;  2J0X A;  1ZL3 A;  1Q7H A;  1E19 A;  1WXW A;  3C1M A;  3ZV0 C;  1B7B A;  2V5H A;  3T7B A;  4A7X A;  2WE5 A;  4NDP A;  4NDR B;  2OGX A;  1ZBO A;  3QUN A;  2WE4 A;  2OGX B;  1GSJ A;  3QVH A;  3AB2 A;  3HJW A;  3EK5 A;  3M6U A;  2RFK A;  2B78 A;  3K52 A;  3WWM A;  1WXX A;  3VSE A;  4DMG A;  1R3F A;  3LL5 A;  1J2B A;  1IT8 A;  3D40 A;  3ZZF A;  3S6K A;  2J4J A;  4NDR A;  2WXB A;  3IUW A;  4CI1 B;  2KKU A;  3LWQ A;  1R3E A;  4USJ A;  3MQK A;  1ZE2 A;  1GS5 A;  4AB7 A;  1UOY A;  4JZ7 A;  3K56 A;  3WWN A;  1K8W A;  3M4X A;  2FRX A;  3LL9 A;  1SGV A;  1OHA A;  4NDO A;  2BMU A;  1T5Y A;  4NDO B;  3M6W A;  2DP9 A;  2HVY A;  2BUF A;  3AB4 A;  3K4O A;  2BRI A;  3LWO A;  4Q1T A;  4KZT A;  4F6T A;  4CI3 B;  1ZS7 A;  3L76 A;  3QVF A;  1XNE A;  3D2M A;  3QUR A;  3M6X A;  2JI5 A;  3HAX A;  2J4K A;  1TE7 A;  1YBD A;  2CX0 A;  3LKK A;  3D79 A;  3U28 A;  2JJ4 A;  2AP9 A;  2R8V A;  2APO A;  4TZ4 C;  3HJY A;  4AXS A;  1S04 A;  4NDQ A;  2E9Y A;  2P38 A;  2J5V A;  1OH9 A;  2W21 A;  2BNE A;  2JJX A;  2AUS A;  3M6V A;  1IQ8 A;  4NDQ B;  4OLC A;  3M65 A;  2IJ9 A;  3K4Y A;  2A1F A;  3LWV A;  2E5O A;  2J4L A;  2RD5 A;  3D2P A;  2Q07 A;  2AKO A;  3S6G A;  2X2W A;  3LWP A;  2AS0 A;  3L86 A;  2J5T A;  1IT7 A;  3LDF A;  3C1N A;  3EK6 A;  3U6U A;  3LWR A;  3ZZH A;  2VA1 A;  2HMF A;  2CDQ A;  2BND A;  4CI2 B; 
#chains in the Genus database with same CATH homology
 2V4Y A;  3S6H A;  3UAI A;  3C20 A;  4F6T B;  4JZ9 A;  4NDP B;  2CX1 A;  3C0K A;  2BRX A;  1OHB A;  4I49 A;  2J0W A;  3NWY A;  4A7W A;  3TVI A;  2R98 A;  1ZE1 A;  3KZF A;  3QUO A;  3B8G A;  3D41 A;  3AAW A;  2AB4 A;  2BNF A;  3ZZG A;  2CWW A;  1Z9D A;  4JZ8 A;  3ZZI A;  2BTY A;  1SQW A;  2J0X A;  1ZL3 A;  1Q7H A;  1E19 A;  1WXW A;  3C1M A;  3T7B A;  1B7B A;  2V5H A;  4A7X A;  2WE5 A;  4NDP A;  4NDR B;  2OGX A;  3QUN A;  2WE4 A;  2OGX B;  1GSJ A;  3QVH A;  3AB2 A;  3EK5 A;  2B78 A;  3K52 A;  3WWM A;  1WXX A;  3VSE A;  4DMG A;  1R3F A;  3LL5 A;  1J2B A;  1IT8 A;  3D40 A;  3ZZF A;  3S6K A;  2J4J A;  4NDR A;  2WXB A;  1R3E A;  4USJ A;  1ZE2 A;  1GS5 A;  4AB7 A;  4JZ7 A;  3K56 A;  3WWN A;  1K8W A;  3LL9 A;  1SGV A;  1OHA A;  4NDO A;  2BMU A;  1T5Y A;  4NDO B;  3AB4 A;  2BUF A;  3K4O A;  2BRI A;  4Q1T A;  4KZT A;  4F6T A;  1ZS7 A;  3L76 A;  3QVF A;  3D2M A;  3QUR A;  2JI5 A;  2J4K A;  1YBD A;  2CX0 A;  3LKK A;  3D79 A;  2JJ4 A;  2AP9 A;  2R8V A;  4AXS A;  4NDQ A;  2E9Y A;  2P38 A;  2J5V A;  1OH9 A;  2W21 A;  2BNE A;  2JJX A;  1IQ8 A;  4NDQ B;  4OLC A;  2IJ9 A;  3K4Y A;  2A1F A;  2J4L A;  2RD5 A;  3D2P A;  2Q07 A;  2AKO A;  3S6G A;  2X2W A;  2AS0 A;  3L86 A;  2J5T A;  1IT7 A;  3LDF A;  3C1N A;  3EK6 A;  3U6U A;  3ZZH A;  2VA1 A;  2HMF A;  2CDQ A;  2BND A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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