2J5VA

Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
365
structure length
323
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords GLUTAMATE 5-KINASE
total genus 116
structure length 323
sequence length 365
chains with identical sequence B
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5vA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5vA01
2BNDA 2AB4A 3ZZGA 2BMUA 2J4JA 2J0XA 4NDRB 1ZS7A 3C0KA 3TVIA 2W21A 1IT8A 1SGVA 2B78A 2BNEA 3D2PA 3L76A 1OHAA 4NDRA 2J0WA 3LKKA 1R3EA 2P38A 2Q07A 1J2BA 2CDQA 3AB2A 4A7XA 3D40A 3WWMA 2V5HA 1WXXA 2X2WA 4NDQA 2J4LA 2J5VA 3QURA 2BNFA 2R98A 3B8GA 2BUFA 2J5TA 2OGXA 2AKOA 3D41A 3C20A 3EK6A 1T5YA 3LL9A 4NDOB 4Q1TA 1B7BA 3EK5A 4F6TA 2R8VA 4NDQB 4AXSA 1OHBA 1ZL3A 3AAWA 3C1MA 3ZZFA 3AB4A 3K56A 2CWWA 3K52A 2BRIA 1IQ8A 4NDOA 2A1FA 2OGXB 3QVHA 3WWNA 1K8WA 3L86A 4USJA 3LDFA 2BRXA 2JJ4A 2WE4A 1OH9A 2HMFA 4KZTA 4DMGA 4F6TB 3VSEA 1GS5A 2IJ9A 1WXWA 3KZFA 4JZ7A 4OLCA 3U6UA 2V4YA 4JZ9A 1R3FA 3D2MA 1IT7A 2VA1A 3UAIA 2AS0A 4NDPA 3C1NA 2CX1A 1Z9DA 2RD5A 3LL5A 3NWYA 1ZE2A 4AB7A 3D79A 2AP9A 2CX0A 2JJXA 4NDPB 3QVFA 3ZZHA 3S6KA 3K4YA 2BTYA 3S6GA 2J4KA 4I49A 4A7WA 2E9YA 1GSJA 3ZZIA 3QUNA 1Q7HA 3S6HA 1YBDA 1SQWA 4JZ8A 2WE5A 2WXBA 3K4OA 1ZE1A 1E19A 3T7BA 2JI5A 3QUOA
chains in the Genus database with same CATH superfamily
2BNDA 2AB4A 3ZZGA 2BMUA 2J4JA 2J0XA 4NDRB 1ZS7A 3C0KA 3TVIA 3MQKA 2W21A 1IT8A 1SGVA 2B78A 4TZ4C 3HAXA 2BNEA 3D2PA 3L76A 1OHAA 4NDRA 2J0WA 3LKKA 1ZBOA 2P38A 2Q07A 1R3EA 1J2BA 2CDQA 3AB2A 3U28A 4A7XA 3D40A 3WWMA 2V5HA 1WXXA 2X2WA 2DP9A 4NDQA 2J4LA 2J5VA 3QURA 2BNFA 2R98A 3B8GA 4CI3B 2BUFA 2AUSA 2J5TA 2OGXA 2AKOA 3ZV0C 3D41A 3C20A 3EK6A 1T5YA 3LL9A 4NDOB 4Q1TA 1B7BA 2FRXA 2APOA 3EK5A 4F6TA 2R8VA 2ANEA 4NDQB 4AXSA 1OHBA 1ZL3A 2Z0TA 3AAWA 3C1MA 3ZZFA 3AB4A 3K56A 2CWWA 3LJCA 3K52A 2BRIA 1IQ8A 4NDOA 2A1FA 2OGXB 3QVHA 3M65A 3WWNA 1XNEA 1K8WA 3L86A 4USJA 1S04A 3LDFA 2BRXA 2EY4A 2JJ4A 2WE4A 4CI1B 1OH9A 2HMFA 4KZTA 4DMGA 4F6TB 3VSEA 1GS5A 2IJ9A 1WXWA 2E5OA 3KZFA 4JZ7A 4OLCA 3U6UA 2RFKA 2V4YA 3M6XA 1R3FA 4JZ9A 3D2MA 1IT7A 2VA1A 3UAIA 3LWRA 2AS0A 3M6UA 4NDPA 3C1NA 2CX1A 1Z9DA 2RD5A 3LL5A 3NWYA 3LWOA 1ZE2A 4AB7A 3D79A 2AP9A 4CI2B 3LWPA 3IUWA 2CX0A 2JJXA 4NDPB 3LWQA 3QVFA 3HJYA 1UOYA 3ZZHA 3S6KA 3K4YA 2BTYA 3S6GA 3M6VA 2J4KA 4I49A 4A7WA 2E9YA 1WK2A 1GSJA 1TE7A 3M4XA 3ZZIA 2KKUA 3QUNA 1Q7HA 3HJWA 3S6HA 1YBDA 2HVYA 1SQWA 4JZ8A 2WE5A 2WXBA 3K4OA 1ZE1A 1E19A 3T7BA 2JI5A 3M6WA 3QUOA 3LWVA
chains in the Genus database with same CATH topology
2BNDA 2AB4A 3ZZGA 2BMUA 2J4JA 2J0XA 4NDRB 1ZS7A 3C0KA 3TVIA 2W21A 1IT8A 1SGVA 2B78A 2BNEA 3D2PA 3L76A 1OHAA 4NDRA 2J0WA 3LKKA 1R3EA 2P38A 2Q07A 1J2BA 2CDQA 3AB2A 4A7XA 3D40A 3WWMA 2V5HA 1WXXA 2X2WA 4NDQA 2J4LA 2J5VA 3QURA 2BNFA 2R98A 3B8GA 2BUFA 2J5TA 2OGXA 2AKOA 3D41A 3C20A 3EK6A 1T5YA 3LL9A 4NDOB 4Q1TA 1B7BA 3EK5A 4F6TA 2R8VA 4NDQB 4AXSA 1OHBA 1ZL3A 3AAWA 3C1MA 3ZZFA 3AB4A 3K56A 2CWWA 3K52A 2BRIA 1IQ8A 4NDOA 2A1FA 2OGXB 3QVHA 3WWNA 1K8WA 3L86A 4USJA 3LDFA 2BRXA 2JJ4A 2WE4A 1OH9A 2HMFA 4KZTA 4DMGA 4F6TB 3VSEA 1GS5A 2IJ9A 1WXWA 3KZFA 4JZ7A 4OLCA 3U6UA 2V4YA 4JZ9A 1R3FA 3D2MA 1IT7A 2VA1A 3UAIA 2AS0A 4NDPA 3C1NA 2CX1A 1Z9DA 2RD5A 3LL5A 3NWYA 1ZE2A 4AB7A 3D79A 2AP9A 2CX0A 2JJXA 4NDPB 3QVFA 3ZZHA 3S6KA 3K4YA 2BTYA 3S6GA 2J4KA 4I49A 4A7WA 2E9YA 1GSJA 3ZZIA 3QUNA 1Q7HA 3S6HA 1YBDA 1SQWA 4JZ8A 2WE5A 2WXBA 3K4OA 1ZE1A 1E19A 3T7BA 2JI5A 3QUOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BND A;  2AB4 A;  3ZZG A;  2BMU A;  2J4J A;  2J0X A;  4NDR B;  1ZS7 A;  3C0K A;  3TVI A;  2W21 A;  1IT8 A;  1SGV A;  2B78 A;  2BNE A;  3D2P A;  3L76 A;  1OHA A;  4NDR A;  2J0W A;  3LKK A;  1R3E A;  2P38 A;  2Q07 A;  1J2B A;  2CDQ A;  3AB2 A;  4A7X A;  3D40 A;  3WWM A;  2V5H A;  1WXX A;  2X2W A;  4NDQ A;  2J4L A;  2J5V A;  3QUR A;  2BNF A;  2R98 A;  3B8G A;  2BUF A;  2J5T A;  2OGX A;  2AKO A;  3D41 A;  3C20 A;  3EK6 A;  1T5Y A;  3LL9 A;  4NDO B;  4Q1T A;  1B7B A;  3EK5 A;  4F6T A;  2R8V A;  4NDQ B;  4AXS A;  1OHB A;  1ZL3 A;  3AAW A;  3C1M A;  3ZZF A;  3AB4 A;  3K56 A;  2CWW A;  3K52 A;  2BRI A;  1IQ8 A;  4NDO A;  2A1F A;  2OGX B;  3QVH A;  3WWN A;  1K8W A;  3L86 A;  4USJ A;  3LDF A;  2BRX A;  2JJ4 A;  2WE4 A;  1OH9 A;  2HMF A;  4KZT A;  4DMG A;  4F6T B;  3VSE A;  1GS5 A;  2IJ9 A;  1WXW A;  3KZF A;  4JZ7 A;  4OLC A;  3U6U A;  2V4Y A;  4JZ9 A;  1R3F A;  3D2M A;  1IT7 A;  2VA1 A;  3UAI A;  2AS0 A;  4NDP A;  3C1N A;  2CX1 A;  1Z9D A;  2RD5 A;  3LL5 A;  3NWY A;  1ZE2 A;  4AB7 A;  3D79 A;  2AP9 A;  2CX0 A;  2JJX A;  4NDP B;  3QVF A;  3ZZH A;  3S6K A;  3K4Y A;  2BTY A;  3S6G A;  2J4K A;  4I49 A;  4A7W A;  2E9Y A;  1GSJ A;  3ZZI A;  3QUN A;  1Q7H A;  3S6H A;  1YBD A;  1SQW A;  4JZ8 A;  2WE5 A;  2WXB A;  3K4O A;  1ZE1 A;  1E19 A;  3T7B A;  2JI5 A;  3QUO A; 
#chains in the Genus database with same CATH topology
 2BND A;  2AB4 A;  3ZZG A;  2BMU A;  2J4J A;  2J0X A;  4NDR B;  1ZS7 A;  3C0K A;  3TVI A;  3MQK A;  2W21 A;  1IT8 A;  1SGV A;  2B78 A;  4TZ4 C;  3HAX A;  2BNE A;  3D2P A;  3L76 A;  1OHA A;  4NDR A;  2J0W A;  3LKK A;  1ZBO A;  2P38 A;  2Q07 A;  1R3E A;  1J2B A;  2CDQ A;  3AB2 A;  3U28 A;  4A7X A;  3D40 A;  3WWM A;  2V5H A;  1WXX A;  2X2W A;  2DP9 A;  4NDQ A;  2J4L A;  2J5V A;  3QUR A;  2BNF A;  2R98 A;  3B8G A;  4CI3 B;  2BUF A;  2AUS A;  2J5T A;  2OGX A;  2AKO A;  3ZV0 C;  3D41 A;  3C20 A;  3EK6 A;  1T5Y A;  3LL9 A;  4NDO B;  4Q1T A;  1B7B A;  2FRX A;  2APO A;  3EK5 A;  4F6T A;  2R8V A;  2ANE A;  4NDQ B;  4AXS A;  1OHB A;  1ZL3 A;  2Z0T A;  3AAW A;  3C1M A;  3ZZF A;  3AB4 A;  3K56 A;  2CWW A;  3LJC A;  3K52 A;  2BRI A;  1IQ8 A;  4NDO A;  2A1F A;  2OGX B;  3QVH A;  3M65 A;  3WWN A;  1XNE A;  1K8W A;  3L86 A;  4USJ A;  1S04 A;  3LDF A;  2BRX A;  2EY4 A;  2JJ4 A;  2WE4 A;  4CI1 B;  1OH9 A;  2HMF A;  4KZT A;  4DMG A;  4F6T B;  3VSE A;  1GS5 A;  2IJ9 A;  1WXW A;  2E5O A;  3KZF A;  4JZ7 A;  4OLC A;  3U6U A;  2RFK A;  2V4Y A;  3M6X A;  1R3F A;  4JZ9 A;  3D2M A;  1IT7 A;  2VA1 A;  3UAI A;  3LWR A;  2AS0 A;  3M6U A;  4NDP A;  3C1N A;  2CX1 A;  1Z9D A;  2RD5 A;  3LL5 A;  3NWY A;  3LWO A;  1ZE2 A;  4AB7 A;  3D79 A;  2AP9 A;  4CI2 B;  3LWP A;  3IUW A;  2CX0 A;  2JJX A;  4NDP B;  3LWQ A;  3QVF A;  3HJY A;  1UOY A;  3ZZH A;  3S6K A;  3K4Y A;  2BTY A;  3S6G A;  3M6V A;  2J4K A;  4I49 A;  4A7W A;  2E9Y A;  1WK2 A;  1GSJ A;  1TE7 A;  3M4X A;  3ZZI A;  2KKU A;  3QUN A;  1Q7H A;  3HJW A;  3S6H A;  1YBD A;  2HVY A;  1SQW A;  4JZ8 A;  2WE5 A;  2WXB A;  3K4O A;  1ZE1 A;  1E19 A;  3T7B A;  2JI5 A;  3M6W A;  3QUO A;  3LWV A; 
#chains in the Genus database with same CATH homology
 2BND A;  2AB4 A;  3ZZG A;  2BMU A;  2J4J A;  2J0X A;  4NDR B;  1ZS7 A;  3C0K A;  3TVI A;  2W21 A;  1IT8 A;  1SGV A;  2B78 A;  2BNE A;  3D2P A;  3L76 A;  1OHA A;  4NDR A;  2J0W A;  3LKK A;  1R3E A;  2P38 A;  2Q07 A;  1J2B A;  2CDQ A;  3AB2 A;  4A7X A;  3D40 A;  3WWM A;  2V5H A;  1WXX A;  2X2W A;  4NDQ A;  2J4L A;  2J5V A;  3QUR A;  2BNF A;  2R98 A;  3B8G A;  2BUF A;  2J5T A;  2OGX A;  2AKO A;  3D41 A;  3C20 A;  3EK6 A;  1T5Y A;  3LL9 A;  4NDO B;  4Q1T A;  1B7B A;  3EK5 A;  4F6T A;  2R8V A;  4NDQ B;  4AXS A;  1OHB A;  1ZL3 A;  3AAW A;  3C1M A;  3ZZF A;  3AB4 A;  3K56 A;  2CWW A;  3K52 A;  2BRI A;  1IQ8 A;  4NDO A;  2A1F A;  2OGX B;  3QVH A;  3WWN A;  1K8W A;  3L86 A;  4USJ A;  3LDF A;  2BRX A;  2JJ4 A;  2WE4 A;  1OH9 A;  2HMF A;  4KZT A;  4DMG A;  4F6T B;  3VSE A;  1GS5 A;  2IJ9 A;  1WXW A;  3KZF A;  4JZ7 A;  4OLC A;  3U6U A;  2V4Y A;  4JZ9 A;  1R3F A;  3D2M A;  1IT7 A;  2VA1 A;  3UAI A;  2AS0 A;  4NDP A;  3C1N A;  2CX1 A;  1Z9D A;  2RD5 A;  3LL5 A;  3NWY A;  1ZE2 A;  4AB7 A;  3D79 A;  2AP9 A;  2CX0 A;  2JJX A;  4NDP B;  3QVF A;  3ZZH A;  3S6K A;  3K4Y A;  2BTY A;  3S6G A;  2J4K A;  4I49 A;  4A7W A;  2E9Y A;  1GSJ A;  3ZZI A;  3QUN A;  1Q7H A;  3S6H A;  1YBD A;  1SQW A;  4JZ8 A;  2WE5 A;  2WXB A;  3K4O A;  1ZE1 A;  1E19 A;  3T7B A;  2JI5 A;  3QUO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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