2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
molecule keywords GLUTAMATE 5-KINASE
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
4USJA 2AKOA 1E19A 2AP9A 3QVFA 3EK6A 2J0WA 1GSJA 2JJXA 3QURA 4A7WA 4F6TB 3KZFA 4F6TA 3EK5A 1Q7HA 3LL9A 2BMUA 2BUFA 3LDFA 3L76A 1J2BA 1R3EA 3K4YA 1Z9DA 3ZZFA 3D41A 2J0XA 1IT7A 2AS0A 2AB4A 2R8VA 1R3FA 4NDPB 3D79A 2B78A 4KZTA 3WWMA 3B8GA 2J4KA 3C1MA 3C1NA 4NDRB 2J4JA 4NDQB 3K52A 1K8WA 4AXSA 2BNFA 3C0KA 4AB7A 4NDQA 2E9YA 4NDRA 1SGVA 4I49A 1OHAA 3D2PA 2WXBA 2CX0A 2CWWA 2VA1A 4NDPA 1B7BA 2J5TA 2V4YA 3AAWA 2OGXA 2WE4A 3ZZIA 2BRXA 4A7XA 2RD5A 1SQWA 1YBDA 1WXXA 2HMFA 3U6UA 1T5YA 1ZL3A 3VSEA 3AB4A 4JZ9A 2BRIA 1ZS7A 1OHBA 1ZE2A 3LL5A 2OGXB 4Q1TA 2BNEA 3K56A 4NDOB 2JJ4A 2JI5A 4OLCA 1ZE1A 4JZ8A 2IJ9A 3TVIA 2BNDA 3K4OA 3LKKA 2P38A 3ZZGA 3C20A 3UAIA 4DMGA 3AB2A 2A1FA 2Q07A 4NDOA 3NWYA 3T7BA 2CX1A 1IQ8A 3L86A 2WE5A 2BTYA 2J5VA 2J4LA 4JZ7A 3S6KA 1GS5A 3S6HA 3QUNA 2CDQA 3QUOA 1IT8A 3S6GA 1OH9A 3D2MA 3ZZHA 2W21A 3WWNA 2X2WA 3D40A 3QVHA 2R98A 2V5HA 1WXWA
chains in the Genus database with same CATH superfamily
4USJA 2AKOA 1E19A 2AP9A 3U28A 4CI1B 3QVFA 3LWVA 3EK6A 2J0WA 1GSJA 2JJXA 3QURA 3LJCA 4A7WA 4F6TB 2APOA 3KZFA 3M6XA 4F6TA 3LWPA 3EK5A 1Q7HA 3LL9A 2BMUA 2BUFA 3LDFA 2RFKA 3L76A 1J2BA 1R3EA 3K4YA 1Z9DA 3HJWA 3ZZFA 3D41A 2J0XA 1IT7A 1XNEA 2E5OA 2AS0A 2AB4A 2R8VA 1R3FA 4NDPB 3D79A 2B78A 3MQKA 4KZTA 3WWMA 2ANEA 2J4KA 3B8GA 3C1MA 2DP9A 3C1NA 4NDRB 2J4JA 4NDQB 4TZ4C 3K52A 1K8WA 4AXSA 2BNFA 3C0KA 4AB7A 4NDQA 2E9YA 4NDRA 1SGVA 4I49A 1OHAA 1TE7A 3D2PA 2CX0A 2CWWA 2WXBA 2VA1A 4NDPA 1B7BA 2J5TA 2V4YA 3AAWA 2OGXA 2WE4A 3ZZIA 2BRXA 4A7XA 2RD5A 1SQWA 1YBDA 1WXXA 4CI3B 3LWQA 3LWRA 2HMFA 3U6UA 1ZBOA 1T5YA 1ZL3A 3VSEA 3AB4A 4JZ9A 3M4XA 2BRIA 1ZS7A 1OHBA 1ZE2A 3LL5A 2OGXB 4Q1TA 2BNEA 3K56A 4NDOB 2JJ4A 2JI5A 4OLCA 3M6UA 1ZE1A 3IUWA 4JZ8A 2IJ9A 2KKUA 3TVIA 2BNDA 3K4OA 3LKKA 2P38A 3ZZGA 3C20A 3UAIA 4DMGA 3AB2A 2A1FA 2Q07A 3LWOA 4NDOA 2HVYA 3NWYA 3T7BA 2CX1A 3HAXA 1IQ8A 1S04A 2AUSA 3M6WA 3HJYA 3L86A 2WE5A 2BTYA 2J5VA 3ZV0C 2EY4A 2J4LA 4JZ7A 3S6KA 1GS5A 4CI2B 3S6HA 3QUNA 2CDQA 3QUOA 1IT8A 2Z0TA 3S6GA 2FRXA 1OH9A 3M65A 3D2MA 3ZZHA 2W21A 3WWNA 3M6VA 2X2WA 3D40A 3QVHA 2R98A 1WK2A 2V5HA 1UOYA 1WXWA
chains in the Genus database with same CATH topology
4USJA 2AKOA 1E19A 2AP9A 3QVFA 3EK6A 2J0WA 1GSJA 2JJXA 3QURA 4A7WA 4F6TB 3KZFA 4F6TA 3EK5A 1Q7HA 3LL9A 2BMUA 2BUFA 3LDFA 3L76A 1J2BA 1R3EA 3K4YA 1Z9DA 3ZZFA 3D41A 2J0XA 1IT7A 2AS0A 2AB4A 2R8VA 1R3FA 4NDPB 3D79A 2B78A 4KZTA 3WWMA 3B8GA 2J4KA 3C1MA 3C1NA 4NDRB 2J4JA 4NDQB 3K52A 1K8WA 4AXSA 2BNFA 3C0KA 4AB7A 4NDQA 2E9YA 4NDRA 1SGVA 4I49A 1OHAA 3D2PA 2WXBA 2CX0A 2CWWA 2VA1A 4NDPA 1B7BA 2J5TA 2V4YA 3AAWA 2OGXA 2WE4A 3ZZIA 2BRXA 4A7XA 2RD5A 1SQWA 1YBDA 1WXXA 2HMFA 3U6UA 1T5YA 1ZL3A 3VSEA 3AB4A 4JZ9A 2BRIA 1ZS7A 1OHBA 1ZE2A 3LL5A 2OGXB 4Q1TA 2BNEA 3K56A 4NDOB 2JJ4A 2JI5A 4OLCA 1ZE1A 4JZ8A 2IJ9A 3TVIA 2BNDA 3K4OA 3LKKA 2P38A 3ZZGA 3C20A 3UAIA 4DMGA 3AB2A 2A1FA 2Q07A 4NDOA 3NWYA 3T7BA 2CX1A 1IQ8A 3L86A 2WE5A 2BTYA 2J5VA 2J4LA 4JZ7A 3S6KA 1GS5A 3S6HA 3QUNA 2CDQA 3QUOA 1IT8A 3S6GA 1OH9A 3D2MA 3ZZHA 2W21A 3WWNA 2X2WA 3D40A 3QVHA 2R98A 2V5HA 1WXWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4USJ A;  2AKO A;  1E19 A;  2AP9 A;  3QVF A;  3EK6 A;  2J0W A;  1GSJ A;  2JJX A;  3QUR A;  4A7W A;  4F6T B;  3KZF A;  4F6T A;  3EK5 A;  1Q7H A;  3LL9 A;  2BMU A;  2BUF A;  3LDF A;  3L76 A;  1J2B A;  1R3E A;  3K4Y A;  1Z9D A;  3ZZF A;  3D41 A;  2J0X A;  1IT7 A;  2AS0 A;  2AB4 A;  2R8V A;  1R3F A;  4NDP B;  3D79 A;  2B78 A;  4KZT A;  3WWM A;  3B8G A;  2J4K A;  3C1M A;  3C1N A;  4NDR B;  2J4J A;  4NDQ B;  3K52 A;  1K8W A;  4AXS A;  2BNF A;  3C0K A;  4AB7 A;  4NDQ A;  2E9Y A;  4NDR A;  1SGV A;  4I49 A;  1OHA A;  3D2P A;  2WXB A;  2CX0 A;  2CWW A;  2VA1 A;  4NDP A;  1B7B A;  2J5T A;  2V4Y A;  3AAW A;  2OGX A;  2WE4 A;  3ZZI A;  2BRX A;  4A7X A;  2RD5 A;  1SQW A;  1YBD A;  1WXX A;  2HMF A;  3U6U A;  1T5Y A;  1ZL3 A;  3VSE A;  3AB4 A;  4JZ9 A;  2BRI A;  1ZS7 A;  1OHB A;  1ZE2 A;  3LL5 A;  2OGX B;  4Q1T A;  2BNE A;  3K56 A;  4NDO B;  2JJ4 A;  2JI5 A;  4OLC A;  1ZE1 A;  4JZ8 A;  2IJ9 A;  3TVI A;  2BND A;  3K4O A;  3LKK A;  2P38 A;  3ZZG A;  3C20 A;  3UAI A;  4DMG A;  3AB2 A;  2A1F A;  2Q07 A;  4NDO A;  3NWY A;  3T7B A;  2CX1 A;  1IQ8 A;  3L86 A;  2WE5 A;  2BTY A;  2J5V A;  2J4L A;  4JZ7 A;  3S6K A;  1GS5 A;  3S6H A;  3QUN A;  2CDQ A;  3QUO A;  1IT8 A;  3S6G A;  1OH9 A;  3D2M A;  3ZZH A;  2W21 A;  3WWN A;  2X2W A;  3D40 A;  3QVH A;  2R98 A;  2V5H A;  1WXW A; 
#chains in the Genus database with same CATH topology
 4USJ A;  2AKO A;  1E19 A;  2AP9 A;  3U28 A;  4CI1 B;  3QVF A;  3LWV A;  3EK6 A;  2J0W A;  1GSJ A;  2JJX A;  3QUR A;  3LJC A;  4A7W A;  4F6T B;  2APO A;  3KZF A;  3M6X A;  4F6T A;  3LWP A;  3EK5 A;  1Q7H A;  3LL9 A;  2BMU A;  2BUF A;  3LDF A;  2RFK A;  3L76 A;  1J2B A;  1R3E A;  3K4Y A;  1Z9D A;  3HJW A;  3ZZF A;  3D41 A;  2J0X A;  1IT7 A;  1XNE A;  2E5O A;  2AS0 A;  2AB4 A;  2R8V A;  1R3F A;  4NDP B;  3D79 A;  2B78 A;  3MQK A;  4KZT A;  3WWM A;  2ANE A;  2J4K A;  3B8G A;  3C1M A;  2DP9 A;  3C1N A;  4NDR B;  2J4J A;  4NDQ B;  4TZ4 C;  3K52 A;  1K8W A;  4AXS A;  2BNF A;  3C0K A;  4AB7 A;  4NDQ A;  2E9Y A;  4NDR A;  1SGV A;  4I49 A;  1OHA A;  1TE7 A;  3D2P A;  2CX0 A;  2CWW A;  2WXB A;  2VA1 A;  4NDP A;  1B7B A;  2J5T A;  2V4Y A;  3AAW A;  2OGX A;  2WE4 A;  3ZZI A;  2BRX A;  4A7X A;  2RD5 A;  1SQW A;  1YBD A;  1WXX A;  4CI3 B;  3LWQ A;  3LWR A;  2HMF A;  3U6U A;  1ZBO A;  1T5Y A;  1ZL3 A;  3VSE A;  3AB4 A;  4JZ9 A;  3M4X A;  2BRI A;  1ZS7 A;  1OHB A;  1ZE2 A;  3LL5 A;  2OGX B;  4Q1T A;  2BNE A;  3K56 A;  4NDO B;  2JJ4 A;  2JI5 A;  4OLC A;  3M6U A;  1ZE1 A;  3IUW A;  4JZ8 A;  2IJ9 A;  2KKU A;  3TVI A;  2BND A;  3K4O A;  3LKK A;  2P38 A;  3ZZG A;  3C20 A;  3UAI A;  4DMG A;  3AB2 A;  2A1F A;  2Q07 A;  3LWO A;  4NDO A;  2HVY A;  3NWY A;  3T7B A;  2CX1 A;  3HAX A;  1IQ8 A;  1S04 A;  2AUS A;  3M6W A;  3HJY A;  3L86 A;  2WE5 A;  2BTY A;  2J5V A;  3ZV0 C;  2EY4 A;  2J4L A;  4JZ7 A;  3S6K A;  1GS5 A;  4CI2 B;  3S6H A;  3QUN A;  2CDQ A;  3QUO A;  1IT8 A;  2Z0T A;  3S6G A;  2FRX A;  1OH9 A;  3M65 A;  3D2M A;  3ZZH A;  2W21 A;  3WWN A;  3M6V A;  2X2W A;  3D40 A;  3QVH A;  2R98 A;  1WK2 A;  2V5H A;  1UOY A;  1WXW A; 
#chains in the Genus database with same CATH homology
 4USJ A;  2AKO A;  1E19 A;  2AP9 A;  3QVF A;  3EK6 A;  2J0W A;  1GSJ A;  2JJX A;  3QUR A;  4A7W A;  4F6T B;  3KZF A;  4F6T A;  3EK5 A;  1Q7H A;  3LL9 A;  2BMU A;  2BUF A;  3LDF A;  3L76 A;  1J2B A;  1R3E A;  3K4Y A;  1Z9D A;  3ZZF A;  3D41 A;  2J0X A;  1IT7 A;  2AS0 A;  2AB4 A;  2R8V A;  1R3F A;  4NDP B;  3D79 A;  2B78 A;  4KZT A;  3WWM A;  3B8G A;  2J4K A;  3C1M A;  3C1N A;  4NDR B;  2J4J A;  4NDQ B;  3K52 A;  1K8W A;  4AXS A;  2BNF A;  3C0K A;  4AB7 A;  4NDQ A;  2E9Y A;  4NDR A;  1SGV A;  4I49 A;  1OHA A;  3D2P A;  2WXB A;  2CX0 A;  2CWW A;  2VA1 A;  4NDP A;  1B7B A;  2J5T A;  2V4Y A;  3AAW A;  2OGX A;  2WE4 A;  3ZZI A;  2BRX A;  4A7X A;  2RD5 A;  1SQW A;  1YBD A;  1WXX A;  2HMF A;  3U6U A;  1T5Y A;  1ZL3 A;  3VSE A;  3AB4 A;  4JZ9 A;  2BRI A;  1ZS7 A;  1OHB A;  1ZE2 A;  3LL5 A;  2OGX B;  4Q1T A;  2BNE A;  3K56 A;  4NDO B;  2JJ4 A;  2JI5 A;  4OLC A;  1ZE1 A;  4JZ8 A;  2IJ9 A;  3TVI A;  2BND A;  3K4O A;  3LKK A;  2P38 A;  3ZZG A;  3C20 A;  3UAI A;  4DMG A;  3AB2 A;  2A1F A;  2Q07 A;  4NDO A;  3NWY A;  3T7B A;  2CX1 A;  1IQ8 A;  3L86 A;  2WE5 A;  2BTY A;  2J5V A;  2J4L A;  4JZ7 A;  3S6K A;  1GS5 A;  3S6H A;  3QUN A;  2CDQ A;  3QUO A;  1IT8 A;  3S6G A;  1OH9 A;  3D2M A;  3ZZH A;  2W21 A;  3WWN A;  2X2W A;  3D40 A;  3QVH A;  2R98 A;  2V5H A;  1WXW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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