2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords GLUTAMATE 5-KINASE
publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
1Z9DA 2P38A 2BUFA 4AXSA 4NDPB 3UAIA 4NDOB 2E9YA 1IQ8A 2AS0A 3AB2A 4NDQA 2R98A 4NDRB 1YBDA 3C1NA 3QVHA 1T5YA 4JZ9A 1ZE1A 1E19A 3EK6A 3KZFA 4KZTA 1R3EA 4F6TB 3K4YA 3QURA 3LL5A 2JJXA 3D40A 2V5HA 1ZL3A 2CDQA 2OGXB 2CX1A 2AB4A 3L86A 2CWWA 3TVIA 2AKOA 2J5TA 2B78A 1K8WA 3AAWA 1IT8A 2CX0A 3C0KA 3K4OA 3D41A 3B8GA 4I49A 3NWYA 2BTYA 2W21A 3L76A 3QUOA 3LL9A 2BNFA 2BRIA 2JJ4A 2J4JA 3QUNA 2BRXA 3K52A 4A7XA 1WXXA 2V4YA 3S6KA 3ZZFA 2BNEA 1OH9A 4NDQB 2IJ9A 4Q1TA 3LKKA 3AB4A 2WXBA 3ZZHA 1B7BA 4AB7A 1OHBA 2X2WA 1SQWA 4OLCA 1GS5A 2OGXA 1SGVA 3LDFA 4A7WA 4NDPA 4NDOA 3S6GA 2WE4A 1R3FA 2J4KA 4USJA 1GSJA 2A1FA 4DMGA 3S6HA 4NDRA 2J0XA 3VSEA 4JZ7A 3D2MA 4F6TA 3D2PA 1ZE2A 2HMFA 3K56A 4JZ8A 2Q07A 3ZZGA 1J2BA 2BNDA 1WXWA 3EK5A 2J4LA 3WWMA 2WE5A 3QVFA 1Q7HA 3T7BA 1OHAA 2VA1A 2J0WA 3D79A 2RD5A 3U6UA 3ZZIA 2AP9A 2BMUA 3WWNA 3C1MA 2R8VA 2JI5A 3C20A 2J5VA 1IT7A 1ZS7A
chains in the Genus database with same CATH superfamily
1Z9DA 2P38A 3LWRA 2BUFA 4AXSA 4NDPB 3UAIA 4NDOB 2E5OA 1IQ8A 2AS0A 2E9YA 1UOYA 3AB2A 3HAXA 2R98A 4NDQA 4NDRB 1YBDA 3C1NA 3QVHA 1T5YA 4JZ9A 1ZE1A 1E19A 3EK6A 3KZFA 4KZTA 1R3EA 3U28A 4F6TB 3K4YA 2KKUA 2ANEA 3QURA 3LL5A 2JJXA 3D40A 2V5HA 1ZL3A 4CI1B 2CDQA 2OGXB 2CX1A 2AB4A 3L86A 2RFKA 2CWWA 3TVIA 2AKOA 3LWQA 2J5TA 2B78A 1K8WA 3AAWA 1IT8A 2Z0TA 2CX0A 3C0KA 3K4OA 3D41A 3B8GA 4I49A 3NWYA 1WK2A 2BTYA 2W21A 3L76A 3QUOA 3LL9A 2BNFA 2BRIA 2JJ4A 1ZBOA 2J4JA 3QUNA 2BRXA 3K52A 1S04A 4A7XA 1WXXA 2V4YA 2EY4A 3M65A 3S6KA 3ZZFA 2BNEA 1OH9A 4NDQB 2IJ9A 4Q1TA 3LKKA 3LWVA 3AB4A 2WXBA 3ZZHA 3MQKA 1B7BA 2AUSA 4AB7A 1OHBA 2X2WA 3HJYA 4CI3B 1SQWA 4OLCA 1GS5A 2OGXA 1SGVA 3LDFA 4A7WA 3M6XA 4NDPA 1XNEA 3M4XA 4NDOA 3S6GA 4TZ4C 2WE4A 1R3FA 2J4KA 4USJA 1GSJA 2A1FA 4DMGA 3S6HA 4NDRA 2J0XA 3VSEA 4JZ7A 1TE7A 3M6WA 3LWPA 3D2MA 3M6VA 4F6TA 3ZV0C 3D2PA 3LJCA 1ZE2A 2HMFA 3K56A 2Q07A 2HVYA 4JZ8A 3HJWA 3ZZGA 1J2BA 2BNDA 1WXWA 3EK5A 2J4LA 3WWMA 2WE5A 3QVFA 1Q7HA 2FRXA 3T7BA 2DP9A 1OHAA 2VA1A 2J0WA 3D79A 2APOA 2RD5A 3LWOA 3U6UA 3ZZIA 2AP9A 2BMUA 3WWNA 3C1MA 2R8VA 2JI5A 3C20A 3IUWA 2J5VA 1IT7A 3M6UA 1ZS7A 4CI2B
chains in the Genus database with same CATH topology
1Z9DA 2P38A 2BUFA 4AXSA 4NDPB 3UAIA 4NDOB 2E9YA 1IQ8A 2AS0A 3AB2A 4NDQA 2R98A 4NDRB 1YBDA 3C1NA 3QVHA 1T5YA 4JZ9A 1ZE1A 1E19A 3EK6A 3KZFA 4KZTA 1R3EA 4F6TB 3K4YA 3QURA 3LL5A 2JJXA 3D40A 2V5HA 1ZL3A 2CDQA 2OGXB 2CX1A 2AB4A 3L86A 2CWWA 3TVIA 2AKOA 2J5TA 2B78A 1K8WA 3AAWA 1IT8A 2CX0A 3C0KA 3K4OA 3D41A 3B8GA 4I49A 3NWYA 2BTYA 2W21A 3L76A 3QUOA 3LL9A 2BNFA 2BRIA 2JJ4A 2J4JA 3QUNA 2BRXA 3K52A 4A7XA 1WXXA 2V4YA 3S6KA 3ZZFA 2BNEA 1OH9A 4NDQB 2IJ9A 4Q1TA 3LKKA 3AB4A 2WXBA 3ZZHA 1B7BA 4AB7A 1OHBA 2X2WA 1SQWA 4OLCA 1GS5A 2OGXA 1SGVA 3LDFA 4A7WA 4NDPA 4NDOA 3S6GA 2WE4A 1R3FA 2J4KA 4USJA 1GSJA 2A1FA 4DMGA 3S6HA 4NDRA 2J0XA 3VSEA 4JZ7A 3D2MA 4F6TA 3D2PA 1ZE2A 2HMFA 3K56A 4JZ8A 2Q07A 3ZZGA 1J2BA 2BNDA 1WXWA 3EK5A 2J4LA 3WWMA 2WE5A 3QVFA 1Q7HA 3T7BA 1OHAA 2VA1A 2J0WA 3D79A 2RD5A 3U6UA 3ZZIA 2AP9A 2BMUA 3WWNA 3C1MA 2R8VA 2JI5A 3C20A 2J5VA 1IT7A 1ZS7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z9D A;  2P38 A;  2BUF A;  4AXS A;  4NDP B;  3UAI A;  4NDO B;  2E9Y A;  1IQ8 A;  2AS0 A;  3AB2 A;  4NDQ A;  2R98 A;  4NDR B;  1YBD A;  3C1N A;  3QVH A;  1T5Y A;  4JZ9 A;  1ZE1 A;  1E19 A;  3EK6 A;  3KZF A;  4KZT A;  1R3E A;  4F6T B;  3K4Y A;  3QUR A;  3LL5 A;  2JJX A;  3D40 A;  2V5H A;  1ZL3 A;  2CDQ A;  2OGX B;  2CX1 A;  2AB4 A;  3L86 A;  2CWW A;  3TVI A;  2AKO A;  2J5T A;  2B78 A;  1K8W A;  3AAW A;  1IT8 A;  2CX0 A;  3C0K A;  3K4O A;  3D41 A;  3B8G A;  4I49 A;  3NWY A;  2BTY A;  2W21 A;  3L76 A;  3QUO A;  3LL9 A;  2BNF A;  2BRI A;  2JJ4 A;  2J4J A;  3QUN A;  2BRX A;  3K52 A;  4A7X A;  1WXX A;  2V4Y A;  3S6K A;  3ZZF A;  2BNE A;  1OH9 A;  4NDQ B;  2IJ9 A;  4Q1T A;  3LKK A;  3AB4 A;  2WXB A;  3ZZH A;  1B7B A;  4AB7 A;  1OHB A;  2X2W A;  1SQW A;  4OLC A;  1GS5 A;  2OGX A;  1SGV A;  3LDF A;  4A7W A;  4NDP A;  4NDO A;  3S6G A;  2WE4 A;  1R3F A;  2J4K A;  4USJ A;  1GSJ A;  2A1F A;  4DMG A;  3S6H A;  4NDR A;  2J0X A;  3VSE A;  4JZ7 A;  3D2M A;  4F6T A;  3D2P A;  1ZE2 A;  2HMF A;  3K56 A;  4JZ8 A;  2Q07 A;  3ZZG A;  1J2B A;  2BND A;  1WXW A;  3EK5 A;  2J4L A;  3WWM A;  2WE5 A;  3QVF A;  1Q7H A;  3T7B A;  1OHA A;  2VA1 A;  2J0W A;  3D79 A;  2RD5 A;  3U6U A;  3ZZI A;  2AP9 A;  2BMU A;  3WWN A;  3C1M A;  2R8V A;  2JI5 A;  3C20 A;  2J5V A;  1IT7 A;  1ZS7 A; 
#chains in the Genus database with same CATH topology
 1Z9D A;  2P38 A;  3LWR A;  2BUF A;  4AXS A;  4NDP B;  3UAI A;  4NDO B;  2E5O A;  1IQ8 A;  2AS0 A;  2E9Y A;  1UOY A;  3AB2 A;  3HAX A;  2R98 A;  4NDQ A;  4NDR B;  1YBD A;  3C1N A;  3QVH A;  1T5Y A;  4JZ9 A;  1ZE1 A;  1E19 A;  3EK6 A;  3KZF A;  4KZT A;  1R3E A;  3U28 A;  4F6T B;  3K4Y A;  2KKU A;  2ANE A;  3QUR A;  3LL5 A;  2JJX A;  3D40 A;  2V5H A;  1ZL3 A;  4CI1 B;  2CDQ A;  2OGX B;  2CX1 A;  2AB4 A;  3L86 A;  2RFK A;  2CWW A;  3TVI A;  2AKO A;  3LWQ A;  2J5T A;  2B78 A;  1K8W A;  3AAW A;  1IT8 A;  2Z0T A;  2CX0 A;  3C0K A;  3K4O A;  3D41 A;  3B8G A;  4I49 A;  3NWY A;  1WK2 A;  2BTY A;  2W21 A;  3L76 A;  3QUO A;  3LL9 A;  2BNF A;  2BRI A;  2JJ4 A;  1ZBO A;  2J4J A;  3QUN A;  2BRX A;  3K52 A;  1S04 A;  4A7X A;  1WXX A;  2V4Y A;  2EY4 A;  3M65 A;  3S6K A;  3ZZF A;  2BNE A;  1OH9 A;  4NDQ B;  2IJ9 A;  4Q1T A;  3LKK A;  3LWV A;  3AB4 A;  2WXB A;  3ZZH A;  3MQK A;  1B7B A;  2AUS A;  4AB7 A;  1OHB A;  2X2W A;  3HJY A;  4CI3 B;  1SQW A;  4OLC A;  1GS5 A;  2OGX A;  1SGV A;  3LDF A;  4A7W A;  3M6X A;  4NDP A;  1XNE A;  3M4X A;  4NDO A;  3S6G A;  4TZ4 C;  2WE4 A;  1R3F A;  2J4K A;  4USJ A;  1GSJ A;  2A1F A;  4DMG A;  3S6H A;  4NDR A;  2J0X A;  3VSE A;  4JZ7 A;  1TE7 A;  3M6W A;  3LWP A;  3D2M A;  3M6V A;  4F6T A;  3ZV0 C;  3D2P A;  3LJC A;  1ZE2 A;  2HMF A;  3K56 A;  2Q07 A;  2HVY A;  4JZ8 A;  3HJW A;  3ZZG A;  1J2B A;  2BND A;  1WXW A;  3EK5 A;  2J4L A;  3WWM A;  2WE5 A;  3QVF A;  1Q7H A;  2FRX A;  3T7B A;  2DP9 A;  1OHA A;  2VA1 A;  2J0W A;  3D79 A;  2APO A;  2RD5 A;  3LWO A;  3U6U A;  3ZZI A;  2AP9 A;  2BMU A;  3WWN A;  3C1M A;  2R8V A;  2JI5 A;  3C20 A;  3IUW A;  2J5V A;  1IT7 A;  3M6U A;  1ZS7 A;  4CI2 B; 
#chains in the Genus database with same CATH homology
 1Z9D A;  2P38 A;  2BUF A;  4AXS A;  4NDP B;  3UAI A;  4NDO B;  2E9Y A;  1IQ8 A;  2AS0 A;  3AB2 A;  4NDQ A;  2R98 A;  4NDR B;  1YBD A;  3C1N A;  3QVH A;  1T5Y A;  4JZ9 A;  1ZE1 A;  1E19 A;  3EK6 A;  3KZF A;  4KZT A;  1R3E A;  4F6T B;  3K4Y A;  3QUR A;  3LL5 A;  2JJX A;  3D40 A;  2V5H A;  1ZL3 A;  2CDQ A;  2OGX B;  2CX1 A;  2AB4 A;  3L86 A;  2CWW A;  3TVI A;  2AKO A;  2J5T A;  2B78 A;  1K8W A;  3AAW A;  1IT8 A;  2CX0 A;  3C0K A;  3K4O A;  3D41 A;  3B8G A;  4I49 A;  3NWY A;  2BTY A;  2W21 A;  3L76 A;  3QUO A;  3LL9 A;  2BNF A;  2BRI A;  2JJ4 A;  2J4J A;  3QUN A;  2BRX A;  3K52 A;  4A7X A;  1WXX A;  2V4Y A;  3S6K A;  3ZZF A;  2BNE A;  1OH9 A;  4NDQ B;  2IJ9 A;  4Q1T A;  3LKK A;  3AB4 A;  2WXB A;  3ZZH A;  1B7B A;  4AB7 A;  1OHB A;  2X2W A;  1SQW A;  4OLC A;  1GS5 A;  2OGX A;  1SGV A;  3LDF A;  4A7W A;  4NDP A;  4NDO A;  3S6G A;  2WE4 A;  1R3F A;  2J4K A;  4USJ A;  1GSJ A;  2A1F A;  4DMG A;  3S6H A;  4NDR A;  2J0X A;  3VSE A;  4JZ7 A;  3D2M A;  4F6T A;  3D2P A;  1ZE2 A;  2HMF A;  3K56 A;  4JZ8 A;  2Q07 A;  3ZZG A;  1J2B A;  2BND A;  1WXW A;  3EK5 A;  2J4L A;  3WWM A;  2WE5 A;  3QVF A;  1Q7H A;  3T7B A;  1OHA A;  2VA1 A;  2J0W A;  3D79 A;  2RD5 A;  3U6U A;  3ZZI A;  2AP9 A;  2BMU A;  3WWN A;  3C1M A;  2R8V A;  2JI5 A;  3C20 A;  2J5V A;  1IT7 A;  1ZS7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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