2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Escherichia coli
molecule keywords GLUTAMATE 5-KINASE
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
3C1MA 1K8WA 3UAIA 2BNDA 3KZFA 4NDQA 2CWWA 4F6TB 4JZ9A 2AB4A 4NDRA 4I49A 4KZTA 1Z9DA 4OLCA 2A1FA 3QVHA 2VA1A 2J5TA 2AP9A 2WE5A 2OGXA 1B7BA 4NDQB 2P38A 4Q1TA 1OHBA 4NDPA 4NDRB 2JJ4A 3AB4A 4DMGA 2J4KA 3K4YA 2B78A 1R3FA 2BNEA 1SQWA 1YBDA 2BMUA 3AAWA 2HMFA 1ZS7A 4JZ8A 2OGXB 2R98A 1J2BA 2J4LA 1OH9A 3D2PA 4NDPB 2WXBA 4NDOB 4A7XA 1E19A 2V5HA 2BUFA 2CX0A 1WXWA 2V4YA 2J0WA 3NWYA 1GSJA 2BTYA 3QVFA 2CX1A 3S6HA 2J4JA 3D40A 1ZE1A 1GS5A 3B8GA 2R8VA 3C1NA 3D2MA 3L76A 3QUNA 3K52A 1Q7HA 4JZ7A 2BRXA 1IT7A 3S6KA 3WWMA 1IQ8A 3QUOA 3ZZGA 4AXSA 3LL9A 2JI5A 3C20A 2J5VA 3ZZFA 2AKOA 3S6GA 2IJ9A 3C0KA 2CDQA 4F6TA 2JJXA 3T7BA 2BNFA 1SGVA 2W21A 3WWNA 3L86A 4USJA 1T5YA 1OHAA 2J0XA 4AB7A 3D79A 3TVIA 2BRIA 2E9YA 3AB2A 1WXXA 2Q07A 2RD5A 3LKKA 3U6UA 3K4OA 3EK5A 1ZE2A 2AS0A 2X2WA 3ZZHA 3VSEA 3K56A 3ZZIA 4A7WA 3QURA 3LL5A 3D41A 1R3EA 4NDOA 1ZL3A 2WE4A 3LDFA 1IT8A 3EK6A
chains in the Genus database with same CATH superfamily
3C1MA 1K8WA 2E5OA 3UAIA 2BNDA 3KZFA 3LWVA 2CWWA 2KKUA 1UOYA 3LWRA 4NDQA 4F6TB 4JZ9A 2AB4A 4NDRA 4I49A 4KZTA 3MQKA 1Z9DA 4OLCA 2A1FA 3QVHA 2VA1A 2J5TA 3EK6A 2AP9A 2WE5A 2DP9A 1B7BA 2OGXA 3ZV0C 4NDQB 2P38A 4Q1TA 1OHBA 4NDPA 4NDRB 2JJ4A 3AB4A 4DMGA 2J4KA 3K4YA 2B78A 1R3FA 2BNEA 1XNEA 1SQWA 1YBDA 2BMUA 3AAWA 2HMFA 1ZS7A 1TE7A 4JZ8A 3U28A 2HVYA 2OGXB 2R98A 1J2BA 2FRXA 2J4LA 1OH9A 3D2PA 4NDPB 2WXBA 1WK2A 3LWQA 4NDOB 4A7XA 1E19A 3M6XA 2V5HA 2BUFA 3M6UA 4CI3B 2CX0A 1WXWA 2Z0TA 2V4YA 2J0WA 3LWOA 3NWYA 2AUSA 1GSJA 2BTYA 3QVFA 2CX1A 3S6HA 2J4JA 3D40A 1ZE1A 1GS5A 3B8GA 2R8VA 3C1NA 3D2MA 3L76A 3QUNA 1ZBOA 3K52A 1Q7HA 4JZ7A 4CI2B 2BRXA 1IT7A 3S6KA 3WWMA 1IQ8A 3QUOA 3IUWA 3ZZGA 4AXSA 3HJYA 3LL9A 3LJCA 2JI5A 3C20A 3LWPA 2APOA 2J5VA 3ZZFA 2AKOA 3S6GA 2IJ9A 3C0KA 2CDQA 4F6TA 2JJXA 3T7BA 2BNFA 1SGVA 4CI1B 3HAXA 2W21A 3WWNA 3L86A 4USJA 3M6VA 1T5YA 1OHAA 2J0XA 4AB7A 3D79A 3TVIA 2BRIA 2RFKA 3M65A 2E9YA 1S04A 3AB2A 1WXXA 2Q07A 2RD5A 3LKKA 3U6UA 3K4OA 3EK5A 3M6WA 4TZ4C 2EY4A 1ZE2A 2AS0A 2X2WA 2ANEA 3HJWA 3ZZHA 3VSEA 3K56A 3ZZIA 4A7WA 3QURA 3LL5A 3D41A 1R3EA 4NDOA 1ZL3A 2WE4A 3LDFA 1IT8A 3M4XA
chains in the Genus database with same CATH topology
3C1MA 1K8WA 3UAIA 2BNDA 3KZFA 4NDQA 2CWWA 4F6TB 4JZ9A 2AB4A 4NDRA 4I49A 4KZTA 1Z9DA 4OLCA 2A1FA 3QVHA 2VA1A 2J5TA 2AP9A 2WE5A 2OGXA 1B7BA 4NDQB 2P38A 4Q1TA 1OHBA 4NDPA 4NDRB 2JJ4A 3AB4A 4DMGA 2J4KA 3K4YA 2B78A 1R3FA 2BNEA 1SQWA 1YBDA 2BMUA 3AAWA 2HMFA 1ZS7A 4JZ8A 2OGXB 2R98A 1J2BA 2J4LA 1OH9A 3D2PA 4NDPB 2WXBA 4NDOB 4A7XA 1E19A 2V5HA 2BUFA 2CX0A 1WXWA 2V4YA 2J0WA 3NWYA 1GSJA 2BTYA 3QVFA 2CX1A 3S6HA 2J4JA 3D40A 1ZE1A 1GS5A 3B8GA 2R8VA 3C1NA 3D2MA 3L76A 3QUNA 3K52A 1Q7HA 4JZ7A 2BRXA 1IT7A 3S6KA 3WWMA 1IQ8A 3QUOA 3ZZGA 4AXSA 3LL9A 2JI5A 3C20A 2J5VA 3ZZFA 2AKOA 3S6GA 2IJ9A 3C0KA 2CDQA 4F6TA 2JJXA 3T7BA 2BNFA 1SGVA 2W21A 3WWNA 3L86A 4USJA 1T5YA 1OHAA 2J0XA 4AB7A 3D79A 3TVIA 2BRIA 2E9YA 3AB2A 1WXXA 2Q07A 2RD5A 3LKKA 3U6UA 3K4OA 3EK5A 1ZE2A 2AS0A 2X2WA 3ZZHA 3VSEA 3K56A 3ZZIA 4A7WA 3QURA 3LL5A 3D41A 1R3EA 4NDOA 1ZL3A 2WE4A 3LDFA 1IT8A 3EK6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C1M A;  1K8W A;  3UAI A;  2BND A;  3KZF A;  4NDQ A;  2CWW A;  4F6T B;  4JZ9 A;  2AB4 A;  4NDR A;  4I49 A;  4KZT A;  1Z9D A;  4OLC A;  2A1F A;  3QVH A;  2VA1 A;  2J5T A;  2AP9 A;  2WE5 A;  2OGX A;  1B7B A;  4NDQ B;  2P38 A;  4Q1T A;  1OHB A;  4NDP A;  4NDR B;  2JJ4 A;  3AB4 A;  4DMG A;  2J4K A;  3K4Y A;  2B78 A;  1R3F A;  2BNE A;  1SQW A;  1YBD A;  2BMU A;  3AAW A;  2HMF A;  1ZS7 A;  4JZ8 A;  2OGX B;  2R98 A;  1J2B A;  2J4L A;  1OH9 A;  3D2P A;  4NDP B;  2WXB A;  4NDO B;  4A7X A;  1E19 A;  2V5H A;  2BUF A;  2CX0 A;  1WXW A;  2V4Y A;  2J0W A;  3NWY A;  1GSJ A;  2BTY A;  3QVF A;  2CX1 A;  3S6H A;  2J4J A;  3D40 A;  1ZE1 A;  1GS5 A;  3B8G A;  2R8V A;  3C1N A;  3D2M A;  3L76 A;  3QUN A;  3K52 A;  1Q7H A;  4JZ7 A;  2BRX A;  1IT7 A;  3S6K A;  3WWM A;  1IQ8 A;  3QUO A;  3ZZG A;  4AXS A;  3LL9 A;  2JI5 A;  3C20 A;  2J5V A;  3ZZF A;  2AKO A;  3S6G A;  2IJ9 A;  3C0K A;  2CDQ A;  4F6T A;  2JJX A;  3T7B A;  2BNF A;  1SGV A;  2W21 A;  3WWN A;  3L86 A;  4USJ A;  1T5Y A;  1OHA A;  2J0X A;  4AB7 A;  3D79 A;  3TVI A;  2BRI A;  2E9Y A;  3AB2 A;  1WXX A;  2Q07 A;  2RD5 A;  3LKK A;  3U6U A;  3K4O A;  3EK5 A;  1ZE2 A;  2AS0 A;  2X2W A;  3ZZH A;  3VSE A;  3K56 A;  3ZZI A;  4A7W A;  3QUR A;  3LL5 A;  3D41 A;  1R3E A;  4NDO A;  1ZL3 A;  2WE4 A;  3LDF A;  1IT8 A;  3EK6 A; 
#chains in the Genus database with same CATH topology
 3C1M A;  1K8W A;  2E5O A;  3UAI A;  2BND A;  3KZF A;  3LWV A;  2CWW A;  2KKU A;  1UOY A;  3LWR A;  4NDQ A;  4F6T B;  4JZ9 A;  2AB4 A;  4NDR A;  4I49 A;  4KZT A;  3MQK A;  1Z9D A;  4OLC A;  2A1F A;  3QVH A;  2VA1 A;  2J5T A;  3EK6 A;  2AP9 A;  2WE5 A;  2DP9 A;  1B7B A;  2OGX A;  3ZV0 C;  4NDQ B;  2P38 A;  4Q1T A;  1OHB A;  4NDP A;  4NDR B;  2JJ4 A;  3AB4 A;  4DMG A;  2J4K A;  3K4Y A;  2B78 A;  1R3F A;  2BNE A;  1XNE A;  1SQW A;  1YBD A;  2BMU A;  3AAW A;  2HMF A;  1ZS7 A;  1TE7 A;  4JZ8 A;  3U28 A;  2HVY A;  2OGX B;  2R98 A;  1J2B A;  2FRX A;  2J4L A;  1OH9 A;  3D2P A;  4NDP B;  2WXB A;  1WK2 A;  3LWQ A;  4NDO B;  4A7X A;  1E19 A;  3M6X A;  2V5H A;  2BUF A;  3M6U A;  4CI3 B;  2CX0 A;  1WXW A;  2Z0T A;  2V4Y A;  2J0W A;  3LWO A;  3NWY A;  2AUS A;  1GSJ A;  2BTY A;  3QVF A;  2CX1 A;  3S6H A;  2J4J A;  3D40 A;  1ZE1 A;  1GS5 A;  3B8G A;  2R8V A;  3C1N A;  3D2M A;  3L76 A;  3QUN A;  1ZBO A;  3K52 A;  1Q7H A;  4JZ7 A;  4CI2 B;  2BRX A;  1IT7 A;  3S6K A;  3WWM A;  1IQ8 A;  3QUO A;  3IUW A;  3ZZG A;  4AXS A;  3HJY A;  3LL9 A;  3LJC A;  2JI5 A;  3C20 A;  3LWP A;  2APO A;  2J5V A;  3ZZF A;  2AKO A;  3S6G A;  2IJ9 A;  3C0K A;  2CDQ A;  4F6T A;  2JJX A;  3T7B A;  2BNF A;  1SGV A;  4CI1 B;  3HAX A;  2W21 A;  3WWN A;  3L86 A;  4USJ A;  3M6V A;  1T5Y A;  1OHA A;  2J0X A;  4AB7 A;  3D79 A;  3TVI A;  2BRI A;  2RFK A;  3M65 A;  2E9Y A;  1S04 A;  3AB2 A;  1WXX A;  2Q07 A;  2RD5 A;  3LKK A;  3U6U A;  3K4O A;  3EK5 A;  3M6W A;  4TZ4 C;  2EY4 A;  1ZE2 A;  2AS0 A;  2X2W A;  2ANE A;  3HJW A;  3ZZH A;  3VSE A;  3K56 A;  3ZZI A;  4A7W A;  3QUR A;  3LL5 A;  3D41 A;  1R3E A;  4NDO A;  1ZL3 A;  2WE4 A;  3LDF A;  1IT8 A;  3M4X A; 
#chains in the Genus database with same CATH homology
 3C1M A;  1K8W A;  3UAI A;  2BND A;  3KZF A;  4NDQ A;  2CWW A;  4F6T B;  4JZ9 A;  2AB4 A;  4NDR A;  4I49 A;  4KZT A;  1Z9D A;  4OLC A;  2A1F A;  3QVH A;  2VA1 A;  2J5T A;  2AP9 A;  2WE5 A;  2OGX A;  1B7B A;  4NDQ B;  2P38 A;  4Q1T A;  1OHB A;  4NDP A;  4NDR B;  2JJ4 A;  3AB4 A;  4DMG A;  2J4K A;  3K4Y A;  2B78 A;  1R3F A;  2BNE A;  1SQW A;  1YBD A;  2BMU A;  3AAW A;  2HMF A;  1ZS7 A;  4JZ8 A;  2OGX B;  2R98 A;  1J2B A;  2J4L A;  1OH9 A;  3D2P A;  4NDP B;  2WXB A;  4NDO B;  4A7X A;  1E19 A;  2V5H A;  2BUF A;  2CX0 A;  1WXW A;  2V4Y A;  2J0W A;  3NWY A;  1GSJ A;  2BTY A;  3QVF A;  2CX1 A;  3S6H A;  2J4J A;  3D40 A;  1ZE1 A;  1GS5 A;  3B8G A;  2R8V A;  3C1N A;  3D2M A;  3L76 A;  3QUN A;  3K52 A;  1Q7H A;  4JZ7 A;  2BRX A;  1IT7 A;  3S6K A;  3WWM A;  1IQ8 A;  3QUO A;  3ZZG A;  4AXS A;  3LL9 A;  2JI5 A;  3C20 A;  2J5V A;  3ZZF A;  2AKO A;  3S6G A;  2IJ9 A;  3C0K A;  2CDQ A;  4F6T A;  2JJX A;  3T7B A;  2BNF A;  1SGV A;  2W21 A;  3WWN A;  3L86 A;  4USJ A;  1T5Y A;  1OHA A;  2J0X A;  4AB7 A;  3D79 A;  3TVI A;  2BRI A;  2E9Y A;  3AB2 A;  1WXX A;  2Q07 A;  2RD5 A;  3LKK A;  3U6U A;  3K4O A;  3EK5 A;  1ZE2 A;  2AS0 A;  2X2W A;  3ZZH A;  3VSE A;  3K56 A;  3ZZI A;  4A7W A;  3QUR A;  3LL5 A;  3D41 A;  1R3E A;  4NDO A;  1ZL3 A;  2WE4 A;  3LDF A;  1IT8 A;  3EK6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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