2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
molecule keywords GLUTAMATE 5-KINASE
publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
1IQ8A 1WXWA 2IJ9A 2X2WA 1GSJA 4DMGA 3ZZIA 2V5HA 4AB7A 3ZZHA 3ZZGA 2BRIA 2BRXA 3LL5A 1OHAA 2BTYA 1WXXA 3C1MA 1Z9DA 2BUFA 4USJA 2J5TA 4I49A 2JI5A 1ZE2A 3VSEA 4NDPA 4A7XA 2BNFA 3B8GA 2V4YA 2J5VA 2BNEA 2R98A 1IT8A 3K56A 3D40A 4F6TB 1YBDA 2J0XA 4JZ8A 3D41A 1ZE1A 3LDFA 4JZ9A 3LL9A 4NDQB 3S6GA 4Q1TA 3C1NA 3QVFA 2E9YA 3C0KA 3ZZFA 3C20A 3QURA 4NDRA 3L86A 2R8VA 3T7BA 3D79A 2OGXA 1R3EA 3QUNA 2WE5A 2BNDA 3KZFA 1OH9A 2B78A 2CX0A 1Q7HA 1R3FA 2JJXA 1ZS7A 4NDOA 2P38A 3S6HA 2AP9A 1T5YA 2VA1A 2CX1A 3AB2A 2J4KA 1B7BA 2AKOA 2CDQA 4NDPB 3UAIA 2HMFA 3QUOA 2J4LA 3QVHA 3NWYA 3D2MA 3AB4A 2RD5A 1ZL3A 3K4YA 3L76A 2AS0A 1GS5A 3D2PA 4AXSA 3WWNA 4F6TA 2W21A 1E19A 1SQWA 3LKKA 4KZTA 4OLCA 3K4OA 3K52A 4NDRB 4A7WA 3AAWA 4NDQA 2OGXB 3EK5A 1SGVA 2WE4A 3TVIA 2CWWA 1J2BA 1OHBA 2AB4A 1K8WA 4JZ7A 3S6KA 2WXBA 2A1FA 4NDOB 2J4JA 3U6UA 2J0WA 3WWMA 2JJ4A 2BMUA 2Q07A 1IT7A 3EK6A
chains in the Genus database with same CATH superfamily
2E5OA 1IQ8A 1WXWA 2IJ9A 2X2WA 1GSJA 4DMGA 3ZZIA 2V5HA 2HVYA 4AB7A 3ZV0C 3M65A 3ZZHA 3ZZGA 2BRIA 2BRXA 3LL5A 1OHAA 2BTYA 1WXXA 3C1MA 1Z9DA 2BUFA 1UOYA 4USJA 2J5TA 4I49A 2JI5A 1ZE2A 3VSEA 4NDPA 4A7XA 2BNFA 3B8GA 2V4YA 2J5VA 2BNEA 2ANEA 2R98A 1IT8A 3K56A 3D40A 3HJYA 4F6TB 3U28A 1YBDA 2J0XA 4JZ8A 3D41A 1ZE1A 3LDFA 4JZ9A 3LL9A 3LJCA 4NDQB 3S6GA 4Q1TA 3C1NA 3QVFA 2E9YA 3C0KA 3ZZFA 2Z0TA 3C20A 1WK2A 3LWOA 3QURA 4NDRA 3L86A 2R8VA 3T7BA 3D79A 2OGXA 1R3EA 3QUNA 2WE5A 3M6WA 2BNDA 3KZFA 1OH9A 2B78A 2CX0A 1Q7HA 1R3FA 2JJXA 1ZS7A 4NDOA 3HAXA 1S04A 3MQKA 2P38A 3S6HA 2AP9A 1T5YA 2VA1A 1XNEA 2CX1A 3AB2A 2AUSA 2J4KA 3LWRA 1B7BA 2AKOA 2CDQA 4CI1B 2EY4A 4NDPB 3UAIA 2HMFA 3QUOA 2DP9A 2J4LA 3IUWA 3QVHA 3NWYA 3D2MA 3AB4A 3M6UA 2RD5A 3HJWA 4CI3B 2RFKA 3M4XA 4CI2B 1ZL3A 3K4YA 3L76A 3LWQA 2AS0A 1GS5A 3D2PA 4AXSA 3WWNA 4F6TA 3LWPA 2W21A 1E19A 1SQWA 3M6XA 1TE7A 2JJ4A 3LKKA 4KZTA 4OLCA 3LWVA 3K4OA 3K52A 4NDRB 4A7WA 3AAWA 4NDQA 2OGXB 3M6VA 3EK5A 1SGVA 4TZ4C 2WE4A 3TVIA 1J2BA 1OHBA 2AB4A 2KKUA 1K8WA 4JZ7A 1ZBOA 3S6KA 2WXBA 2A1FA 4NDOB 2APOA 2J4JA 3U6UA 2J0WA 2FRXA 3WWMA 2CWWA 2BMUA 2Q07A 1IT7A 3EK6A
chains in the Genus database with same CATH topology
1IQ8A 1WXWA 2IJ9A 2X2WA 1GSJA 4DMGA 3ZZIA 2V5HA 4AB7A 3ZZHA 3ZZGA 2BRIA 2BRXA 3LL5A 1OHAA 2BTYA 1WXXA 3C1MA 1Z9DA 2BUFA 4USJA 2J5TA 4I49A 2JI5A 1ZE2A 3VSEA 4NDPA 4A7XA 2BNFA 3B8GA 2V4YA 2J5VA 2BNEA 2R98A 1IT8A 3K56A 3D40A 4F6TB 1YBDA 2J0XA 4JZ8A 3D41A 1ZE1A 3LDFA 4JZ9A 3LL9A 4NDQB 3S6GA 4Q1TA 3C1NA 3QVFA 2E9YA 3C0KA 3ZZFA 3C20A 3QURA 4NDRA 3L86A 2R8VA 3T7BA 3D79A 2OGXA 1R3EA 3QUNA 2WE5A 2BNDA 3KZFA 1OH9A 2B78A 2CX0A 1Q7HA 1R3FA 2JJXA 1ZS7A 4NDOA 2P38A 3S6HA 2AP9A 1T5YA 2VA1A 2CX1A 3AB2A 2J4KA 1B7BA 2AKOA 2CDQA 4NDPB 3UAIA 2HMFA 3QUOA 2J4LA 3QVHA 3NWYA 3D2MA 3AB4A 2RD5A 1ZL3A 3K4YA 3L76A 2AS0A 1GS5A 3D2PA 4AXSA 3WWNA 4F6TA 2W21A 1E19A 1SQWA 3LKKA 4KZTA 4OLCA 3K4OA 3K52A 4NDRB 4A7WA 3AAWA 4NDQA 2OGXB 3EK5A 1SGVA 2WE4A 3TVIA 2CWWA 1J2BA 1OHBA 2AB4A 1K8WA 4JZ7A 3S6KA 2WXBA 2A1FA 4NDOB 2J4JA 3U6UA 2J0WA 3WWMA 2JJ4A 2BMUA 2Q07A 1IT7A 3EK6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1IQ8 A;  1WXW A;  2IJ9 A;  2X2W A;  1GSJ A;  4DMG A;  3ZZI A;  2V5H A;  4AB7 A;  3ZZH A;  3ZZG A;  2BRI A;  2BRX A;  3LL5 A;  1OHA A;  2BTY A;  1WXX A;  3C1M A;  1Z9D A;  2BUF A;  4USJ A;  2J5T A;  4I49 A;  2JI5 A;  1ZE2 A;  3VSE A;  4NDP A;  4A7X A;  2BNF A;  3B8G A;  2V4Y A;  2J5V A;  2BNE A;  2R98 A;  1IT8 A;  3K56 A;  3D40 A;  4F6T B;  1YBD A;  2J0X A;  4JZ8 A;  3D41 A;  1ZE1 A;  3LDF A;  4JZ9 A;  3LL9 A;  4NDQ B;  3S6G A;  4Q1T A;  3C1N A;  3QVF A;  2E9Y A;  3C0K A;  3ZZF A;  3C20 A;  3QUR A;  4NDR A;  3L86 A;  2R8V A;  3T7B A;  3D79 A;  2OGX A;  1R3E A;  3QUN A;  2WE5 A;  2BND A;  3KZF A;  1OH9 A;  2B78 A;  2CX0 A;  1Q7H A;  1R3F A;  2JJX A;  1ZS7 A;  4NDO A;  2P38 A;  3S6H A;  2AP9 A;  1T5Y A;  2VA1 A;  2CX1 A;  3AB2 A;  2J4K A;  1B7B A;  2AKO A;  2CDQ A;  4NDP B;  3UAI A;  2HMF A;  3QUO A;  2J4L A;  3QVH A;  3NWY A;  3D2M A;  3AB4 A;  2RD5 A;  1ZL3 A;  3K4Y A;  3L76 A;  2AS0 A;  1GS5 A;  3D2P A;  4AXS A;  3WWN A;  4F6T A;  2W21 A;  1E19 A;  1SQW A;  3LKK A;  4KZT A;  4OLC A;  3K4O A;  3K52 A;  4NDR B;  4A7W A;  3AAW A;  4NDQ A;  2OGX B;  3EK5 A;  1SGV A;  2WE4 A;  3TVI A;  2CWW A;  1J2B A;  1OHB A;  2AB4 A;  1K8W A;  4JZ7 A;  3S6K A;  2WXB A;  2A1F A;  4NDO B;  2J4J A;  3U6U A;  2J0W A;  3WWM A;  2JJ4 A;  2BMU A;  2Q07 A;  1IT7 A;  3EK6 A; 
#chains in the Genus database with same CATH topology
 2E5O A;  1IQ8 A;  1WXW A;  2IJ9 A;  2X2W A;  1GSJ A;  4DMG A;  3ZZI A;  2V5H A;  2HVY A;  4AB7 A;  3ZV0 C;  3M65 A;  3ZZH A;  3ZZG A;  2BRI A;  2BRX A;  3LL5 A;  1OHA A;  2BTY A;  1WXX A;  3C1M A;  1Z9D A;  2BUF A;  1UOY A;  4USJ A;  2J5T A;  4I49 A;  2JI5 A;  1ZE2 A;  3VSE A;  4NDP A;  4A7X A;  2BNF A;  3B8G A;  2V4Y A;  2J5V A;  2BNE A;  2ANE A;  2R98 A;  1IT8 A;  3K56 A;  3D40 A;  3HJY A;  4F6T B;  3U28 A;  1YBD A;  2J0X A;  4JZ8 A;  3D41 A;  1ZE1 A;  3LDF A;  4JZ9 A;  3LL9 A;  3LJC A;  4NDQ B;  3S6G A;  4Q1T A;  3C1N A;  3QVF A;  2E9Y A;  3C0K A;  3ZZF A;  2Z0T A;  3C20 A;  1WK2 A;  3LWO A;  3QUR A;  4NDR A;  3L86 A;  2R8V A;  3T7B A;  3D79 A;  2OGX A;  1R3E A;  3QUN A;  2WE5 A;  3M6W A;  2BND A;  3KZF A;  1OH9 A;  2B78 A;  2CX0 A;  1Q7H A;  1R3F A;  2JJX A;  1ZS7 A;  4NDO A;  3HAX A;  1S04 A;  3MQK A;  2P38 A;  3S6H A;  2AP9 A;  1T5Y A;  2VA1 A;  1XNE A;  2CX1 A;  3AB2 A;  2AUS A;  2J4K A;  3LWR A;  1B7B A;  2AKO A;  2CDQ A;  4CI1 B;  2EY4 A;  4NDP B;  3UAI A;  2HMF A;  3QUO A;  2DP9 A;  2J4L A;  3IUW A;  3QVH A;  3NWY A;  3D2M A;  3AB4 A;  3M6U A;  2RD5 A;  3HJW A;  4CI3 B;  2RFK A;  3M4X A;  4CI2 B;  1ZL3 A;  3K4Y A;  3L76 A;  3LWQ A;  2AS0 A;  1GS5 A;  3D2P A;  4AXS A;  3WWN A;  4F6T A;  3LWP A;  2W21 A;  1E19 A;  1SQW A;  3M6X A;  1TE7 A;  2JJ4 A;  3LKK A;  4KZT A;  4OLC A;  3LWV A;  3K4O A;  3K52 A;  4NDR B;  4A7W A;  3AAW A;  4NDQ A;  2OGX B;  3M6V A;  3EK5 A;  1SGV A;  4TZ4 C;  2WE4 A;  3TVI A;  1J2B A;  1OHB A;  2AB4 A;  2KKU A;  1K8W A;  4JZ7 A;  1ZBO A;  3S6K A;  2WXB A;  2A1F A;  4NDO B;  2APO A;  2J4J A;  3U6U A;  2J0W A;  2FRX A;  3WWM A;  2CWW A;  2BMU A;  2Q07 A;  1IT7 A;  3EK6 A; 
#chains in the Genus database with same CATH homology
 1IQ8 A;  1WXW A;  2IJ9 A;  2X2W A;  1GSJ A;  4DMG A;  3ZZI A;  2V5H A;  4AB7 A;  3ZZH A;  3ZZG A;  2BRI A;  2BRX A;  3LL5 A;  1OHA A;  2BTY A;  1WXX A;  3C1M A;  1Z9D A;  2BUF A;  4USJ A;  2J5T A;  4I49 A;  2JI5 A;  1ZE2 A;  3VSE A;  4NDP A;  4A7X A;  2BNF A;  3B8G A;  2V4Y A;  2J5V A;  2BNE A;  2R98 A;  1IT8 A;  3K56 A;  3D40 A;  4F6T B;  1YBD A;  2J0X A;  4JZ8 A;  3D41 A;  1ZE1 A;  3LDF A;  4JZ9 A;  3LL9 A;  4NDQ B;  3S6G A;  4Q1T A;  3C1N A;  3QVF A;  2E9Y A;  3C0K A;  3ZZF A;  3C20 A;  3QUR A;  4NDR A;  3L86 A;  2R8V A;  3T7B A;  3D79 A;  2OGX A;  1R3E A;  3QUN A;  2WE5 A;  2BND A;  3KZF A;  1OH9 A;  2B78 A;  2CX0 A;  1Q7H A;  1R3F A;  2JJX A;  1ZS7 A;  4NDO A;  2P38 A;  3S6H A;  2AP9 A;  1T5Y A;  2VA1 A;  2CX1 A;  3AB2 A;  2J4K A;  1B7B A;  2AKO A;  2CDQ A;  4NDP B;  3UAI A;  2HMF A;  3QUO A;  2J4L A;  3QVH A;  3NWY A;  3D2M A;  3AB4 A;  2RD5 A;  1ZL3 A;  3K4Y A;  3L76 A;  2AS0 A;  1GS5 A;  3D2P A;  4AXS A;  3WWN A;  4F6T A;  2W21 A;  1E19 A;  1SQW A;  3LKK A;  4KZT A;  4OLC A;  3K4O A;  3K52 A;  4NDR B;  4A7W A;  3AAW A;  4NDQ A;  2OGX B;  3EK5 A;  1SGV A;  2WE4 A;  3TVI A;  2CWW A;  1J2B A;  1OHB A;  2AB4 A;  1K8W A;  4JZ7 A;  3S6K A;  2WXB A;  2A1F A;  4NDO B;  2J4J A;  3U6U A;  2J0W A;  3WWM A;  2JJ4 A;  2BMU A;  2Q07 A;  1IT7 A;  3EK6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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