2J5TA

Glutamate 5-kinase from escherichia coli complexed with glutamate
Total Genus 115
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
115
sequence length
365
structure length
355
Chain Sequence
DSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNVVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords GLUTAMATE 5-KINASE
publication title A Novel Two-Domain Architecture within the Amino Acid Kinase Enzyme Family Revealed by the Crystal Structure of Escherichia Coli Glutamate 5-Kinase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Transferase
total genus 115
structure length 355
sequence length 365
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.7.2.11: Glutamate 5-kinase.
pdb deposition date 2006-09-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00696 AA_kinase Amino acid kinase family
A PF01472 PUA PUA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 2j5tA02
3.40.1160.10 Alpha Beta 3-Layer(aba) Sandwich Carbamate kinase Acetylglutamate kinase-like 2j5tA01
1E19A 1GS5A 3QUOA 2BRXA 2V5HA 2BNDA 2BUFA 2J0WA 2CDQA 3EK6A 3U6UA 3WWMA 1WXXA 3L86A 3D2MA 3K4OA 1J2BA 1YBDA 1IQ8A 2AKOA 4Q1TA 3C0KA 2J0XA 2BNFA 2HMFA 3AAWA 3D79A 3C20A 2WE5A 2B78A 4AB7A 3D41A 2VA1A 3ZZFA 1Z9DA 3QUNA 2R98A 3K56A 4F6TB 4NDRA 2J4LA 3S6HA 4NDQA 1K8WA 3ZZHA 2X2WA 4JZ9A 1Q7HA 3LL9A 4A7WA 2RD5A 2J4KA 4KZTA 3QVHA 2J4JA 3AB4A 3LKKA 2WE4A 2AP9A 4JZ7A 3QURA 4DMGA 1R3EA 3UAIA 1IT8A 3C1MA 3ZZGA 1R3FA 3EK5A 4NDPB 2BRIA 1ZE2A 3K4YA 2AS0A 4NDOA 2J5TA 2V4YA 1OHBA 2CWWA 2W21A 4A7XA 1ZL3A 2BTYA 3S6KA 3L76A 2OGXB 1IT7A 3VSEA 2R8VA 1ZS7A 1SGVA 1GSJA 1WXWA 1T5YA 2A1FA 2BNEA 2CX0A 4USJA 3D2PA 4F6TA 1SQWA 4OLCA 4AXSA 4NDRB 3TVIA 3LDFA 4NDQB 3T7BA 3ZZIA 3WWNA 2E9YA 3S6GA 1OH9A 2WXBA 1ZE1A 3NWYA 3D40A 4NDPA 2AB4A 2IJ9A 3B8GA 1B7BA 3C1NA 4NDOB 3LL5A 2JJ4A 4JZ8A 3K52A 4I49A 3AB2A 2BMUA 2Q07A 2OGXA 2P38A 2CX1A 3KZFA 3QVFA 1OHAA 2JI5A 2JJXA 2J5VA
chains in the Genus database with same CATH superfamily
1E19A 1GS5A 3QUOA 2BRXA 2V5HA 2BNDA 2BUFA 2J0WA 2CDQA 3EK6A 3U6UA 3WWMA 3M6XA 1WXXA 3L86A 3D2MA 2HVYA 3LWQA 3K4OA 1TE7A 1J2BA 1YBDA 1IQ8A 3M65A 2AKOA 4Q1TA 3C0KA 4CI3B 2J0XA 2BNFA 2HMFA 3AAWA 3D79A 3C20A 2WE5A 1UOYA 2B78A 4TZ4C 4AB7A 3HJWA 3D41A 2VA1A 3ZZFA 2ANEA 1WK2A 1Z9DA 3QUNA 2R98A 3M6WA 1S04A 3K56A 3HJYA 3ZV0C 4F6TB 4NDRA 3IUWA 2J4LA 3S6HA 4NDQA 1K8WA 1ZBOA 3ZZHA 2X2WA 4JZ9A 1Q7HA 3LL9A 4A7WA 2RD5A 2J4KA 4KZTA 2KKUA 3QVHA 2J4JA 3AB4A 3LKKA 2WE4A 2AP9A 2E5OA 4JZ7A 3QURA 4DMGA 3M6UA 1R3EA 3UAIA 1IT8A 3M6VA 3C1MA 2Z0TA 3ZZGA 1R3FA 3EK5A 4NDPB 2BRIA 1ZE2A 3K4YA 2AS0A 3U28A 4NDOA 1XNEA 2J5TA 2V4YA 1OHBA 2CWWA 2W21A 4A7XA 1ZL3A 2BTYA 3S6KA 3L76A 2OGXB 1IT7A 2DP9A 3VSEA 3MQKA 2R8VA 1ZS7A 1SGVA 1GSJA 1WXWA 1T5YA 2A1FA 2BNEA 2CX0A 4USJA 3D2PA 4F6TA 1SQWA 4OLCA 4AXSA 3HAXA 4NDRB 3TVIA 3LDFA 2FRXA 4NDQB 3T7BA 3LWVA 3ZZIA 3WWNA 2E9YA 3S6GA 3LWPA 1OH9A 2WXBA 1ZE1A 3LWOA 4CI1B 2EY4A 2AUSA 3NWYA 3D40A 4NDPA 2AB4A 2IJ9A 3B8GA 1B7BA 3C1NA 3M4XA 4NDOB 3LL5A 4CI2B 3LJCA 2JJ4A 3LWRA 4JZ8A 3K52A 4I49A 3AB2A 2BMUA 2Q07A 2OGXA 2P38A 2CX1A 3KZFA 3QVFA 1OHAA 2JI5A 2APOA 2JJXA 2J5VA 2RFKA
chains in the Genus database with same CATH topology
1E19A 1GS5A 3QUOA 2BRXA 2V5HA 2BNDA 2BUFA 2J0WA 2CDQA 3EK6A 3U6UA 3WWMA 1WXXA 3L86A 3D2MA 3K4OA 1J2BA 1YBDA 1IQ8A 2AKOA 4Q1TA 3C0KA 2J0XA 2BNFA 2HMFA 3AAWA 3D79A 3C20A 2WE5A 2B78A 4AB7A 3D41A 2VA1A 3ZZFA 1Z9DA 3QUNA 2R98A 3K56A 4F6TB 4NDRA 2J4LA 3S6HA 4NDQA 1K8WA 3ZZHA 2X2WA 4JZ9A 1Q7HA 3LL9A 4A7WA 2RD5A 2J4KA 4KZTA 3QVHA 2J4JA 3AB4A 3LKKA 2WE4A 2AP9A 4JZ7A 3QURA 4DMGA 1R3EA 3UAIA 1IT8A 3C1MA 3ZZGA 1R3FA 3EK5A 4NDPB 2BRIA 1ZE2A 3K4YA 2AS0A 4NDOA 2J5TA 2V4YA 1OHBA 2CWWA 2W21A 4A7XA 1ZL3A 2BTYA 3S6KA 3L76A 2OGXB 1IT7A 3VSEA 2R8VA 1ZS7A 1SGVA 1GSJA 1WXWA 1T5YA 2A1FA 2BNEA 2CX0A 4USJA 3D2PA 4F6TA 1SQWA 4OLCA 4AXSA 4NDRB 3TVIA 3LDFA 4NDQB 3T7BA 3ZZIA 3WWNA 2E9YA 3S6GA 1OH9A 2WXBA 1ZE1A 3NWYA 3D40A 4NDPA 2AB4A 2IJ9A 3B8GA 1B7BA 3C1NA 4NDOB 3LL5A 2JJ4A 4JZ8A 3K52A 4I49A 3AB2A 2BMUA 2Q07A 2OGXA 2P38A 2CX1A 3KZFA 3QVFA 1OHAA 2JI5A 2JJXA 2J5VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1E19 A;  1GS5 A;  3QUO A;  2BRX A;  2V5H A;  2BND A;  2BUF A;  2J0W A;  2CDQ A;  3EK6 A;  3U6U A;  3WWM A;  1WXX A;  3L86 A;  3D2M A;  3K4O A;  1J2B A;  1YBD A;  1IQ8 A;  2AKO A;  4Q1T A;  3C0K A;  2J0X A;  2BNF A;  2HMF A;  3AAW A;  3D79 A;  3C20 A;  2WE5 A;  2B78 A;  4AB7 A;  3D41 A;  2VA1 A;  3ZZF A;  1Z9D A;  3QUN A;  2R98 A;  3K56 A;  4F6T B;  4NDR A;  2J4L A;  3S6H A;  4NDQ A;  1K8W A;  3ZZH A;  2X2W A;  4JZ9 A;  1Q7H A;  3LL9 A;  4A7W A;  2RD5 A;  2J4K A;  4KZT A;  3QVH A;  2J4J A;  3AB4 A;  3LKK A;  2WE4 A;  2AP9 A;  4JZ7 A;  3QUR A;  4DMG A;  1R3E A;  3UAI A;  1IT8 A;  3C1M A;  3ZZG A;  1R3F A;  3EK5 A;  4NDP B;  2BRI A;  1ZE2 A;  3K4Y A;  2AS0 A;  4NDO A;  2J5T A;  2V4Y A;  1OHB A;  2CWW A;  2W21 A;  4A7X A;  1ZL3 A;  2BTY A;  3S6K A;  3L76 A;  2OGX B;  1IT7 A;  3VSE A;  2R8V A;  1ZS7 A;  1SGV A;  1GSJ A;  1WXW A;  1T5Y A;  2A1F A;  2BNE A;  2CX0 A;  4USJ A;  3D2P A;  4F6T A;  1SQW A;  4OLC A;  4AXS A;  4NDR B;  3TVI A;  3LDF A;  4NDQ B;  3T7B A;  3ZZI A;  3WWN A;  2E9Y A;  3S6G A;  1OH9 A;  2WXB A;  1ZE1 A;  3NWY A;  3D40 A;  4NDP A;  2AB4 A;  2IJ9 A;  3B8G A;  1B7B A;  3C1N A;  4NDO B;  3LL5 A;  2JJ4 A;  4JZ8 A;  3K52 A;  4I49 A;  3AB2 A;  2BMU A;  2Q07 A;  2OGX A;  2P38 A;  2CX1 A;  3KZF A;  3QVF A;  1OHA A;  2JI5 A;  2JJX A;  2J5V A; 
#chains in the Genus database with same CATH topology
 1E19 A;  1GS5 A;  3QUO A;  2BRX A;  2V5H A;  2BND A;  2BUF A;  2J0W A;  2CDQ A;  3EK6 A;  3U6U A;  3WWM A;  3M6X A;  1WXX A;  3L86 A;  3D2M A;  2HVY A;  3LWQ A;  3K4O A;  1TE7 A;  1J2B A;  1YBD A;  1IQ8 A;  3M65 A;  2AKO A;  4Q1T A;  3C0K A;  4CI3 B;  2J0X A;  2BNF A;  2HMF A;  3AAW A;  3D79 A;  3C20 A;  2WE5 A;  1UOY A;  2B78 A;  4TZ4 C;  4AB7 A;  3HJW A;  3D41 A;  2VA1 A;  3ZZF A;  2ANE A;  1WK2 A;  1Z9D A;  3QUN A;  2R98 A;  3M6W A;  1S04 A;  3K56 A;  3HJY A;  3ZV0 C;  4F6T B;  4NDR A;  3IUW A;  2J4L A;  3S6H A;  4NDQ A;  1K8W A;  1ZBO A;  3ZZH A;  2X2W A;  4JZ9 A;  1Q7H A;  3LL9 A;  4A7W A;  2RD5 A;  2J4K A;  4KZT A;  2KKU A;  3QVH A;  2J4J A;  3AB4 A;  3LKK A;  2WE4 A;  2AP9 A;  2E5O A;  4JZ7 A;  3QUR A;  4DMG A;  3M6U A;  1R3E A;  3UAI A;  1IT8 A;  3M6V A;  3C1M A;  2Z0T A;  3ZZG A;  1R3F A;  3EK5 A;  4NDP B;  2BRI A;  1ZE2 A;  3K4Y A;  2AS0 A;  3U28 A;  4NDO A;  1XNE A;  2J5T A;  2V4Y A;  1OHB A;  2CWW A;  2W21 A;  4A7X A;  1ZL3 A;  2BTY A;  3S6K A;  3L76 A;  2OGX B;  1IT7 A;  2DP9 A;  3VSE A;  3MQK A;  2R8V A;  1ZS7 A;  1SGV A;  1GSJ A;  1WXW A;  1T5Y A;  2A1F A;  2BNE A;  2CX0 A;  4USJ A;  3D2P A;  4F6T A;  1SQW A;  4OLC A;  4AXS A;  3HAX A;  4NDR B;  3TVI A;  3LDF A;  2FRX A;  4NDQ B;  3T7B A;  3LWV A;  3ZZI A;  3WWN A;  2E9Y A;  3S6G A;  3LWP A;  1OH9 A;  2WXB A;  1ZE1 A;  3LWO A;  4CI1 B;  2EY4 A;  2AUS A;  3NWY A;  3D40 A;  4NDP A;  2AB4 A;  2IJ9 A;  3B8G A;  1B7B A;  3C1N A;  3M4X A;  4NDO B;  3LL5 A;  4CI2 B;  3LJC A;  2JJ4 A;  3LWR A;  4JZ8 A;  3K52 A;  4I49 A;  3AB2 A;  2BMU A;  2Q07 A;  2OGX A;  2P38 A;  2CX1 A;  3KZF A;  3QVF A;  1OHA A;  2JI5 A;  2APO A;  2JJX A;  2J5V A;  2RFK A; 
#chains in the Genus database with same CATH homology
 1E19 A;  1GS5 A;  3QUO A;  2BRX A;  2V5H A;  2BND A;  2BUF A;  2J0W A;  2CDQ A;  3EK6 A;  3U6U A;  3WWM A;  1WXX A;  3L86 A;  3D2M A;  3K4O A;  1J2B A;  1YBD A;  1IQ8 A;  2AKO A;  4Q1T A;  3C0K A;  2J0X A;  2BNF A;  2HMF A;  3AAW A;  3D79 A;  3C20 A;  2WE5 A;  2B78 A;  4AB7 A;  3D41 A;  2VA1 A;  3ZZF A;  1Z9D A;  3QUN A;  2R98 A;  3K56 A;  4F6T B;  4NDR A;  2J4L A;  3S6H A;  4NDQ A;  1K8W A;  3ZZH A;  2X2W A;  4JZ9 A;  1Q7H A;  3LL9 A;  4A7W A;  2RD5 A;  2J4K A;  4KZT A;  3QVH A;  2J4J A;  3AB4 A;  3LKK A;  2WE4 A;  2AP9 A;  4JZ7 A;  3QUR A;  4DMG A;  1R3E A;  3UAI A;  1IT8 A;  3C1M A;  3ZZG A;  1R3F A;  3EK5 A;  4NDP B;  2BRI A;  1ZE2 A;  3K4Y A;  2AS0 A;  4NDO A;  2J5T A;  2V4Y A;  1OHB A;  2CWW A;  2W21 A;  4A7X A;  1ZL3 A;  2BTY A;  3S6K A;  3L76 A;  2OGX B;  1IT7 A;  3VSE A;  2R8V A;  1ZS7 A;  1SGV A;  1GSJ A;  1WXW A;  1T5Y A;  2A1F A;  2BNE A;  2CX0 A;  4USJ A;  3D2P A;  4F6T A;  1SQW A;  4OLC A;  4AXS A;  4NDR B;  3TVI A;  3LDF A;  4NDQ B;  3T7B A;  3ZZI A;  3WWN A;  2E9Y A;  3S6G A;  1OH9 A;  2WXB A;  1ZE1 A;  3NWY A;  3D40 A;  4NDP A;  2AB4 A;  2IJ9 A;  3B8G A;  1B7B A;  3C1N A;  4NDO B;  3LL5 A;  2JJ4 A;  4JZ8 A;  3K52 A;  4I49 A;  3AB2 A;  2BMU A;  2Q07 A;  2OGX A;  2P38 A;  2CX1 A;  3KZF A;  3QVF A;  1OHA A;  2JI5 A;  2JJX A;  2J5V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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