1ZE1A

Conformational change of pseudouridine 55 synthase upon its association with rna substrate
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
308
structure length
308
Chain Sequence
MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFLETLRKHERQRRVLTLRKVFQT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Conformational change of pseudouridine 55 synthase upon its association with RNA substrate
pubmed doi rcsb
molecule tags Lyase
source organism Thermotoga maritima
molecule keywords tRNA pseudouridine synthase B
total genus 77
structure length 308
sequence length 308
chains with identical sequence B, C, D
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 1ze1A02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 1ze1A01
3D79A 2I82A 2RFKA 1IT7A 2CX1A 2APOA 1IQ8A 2Q07A 3DH3A 4DMGA 3HJYA 3LWRA 1T5YA 2CWWA 1KSLA 4LGTA 4LABA 2ISTA 1ZE2A 3LWQA 1QYUA 1V9FA 2CX0A 2HVYA 1K8WA 3LDFA 3VSEA 1KSVA 1XPIA 2AB4A 1WXXA 2AS0A 3HJWA 1ZE1A 1SQWA 2P38A 3LWOA 1Q7HA 3HAXA 1ZS7A 2J5VA 1R3EA 1J2BA 1KSKA 1PRZA 2AUSA 2EY4A 3MQKA 1IT8A 1R3FA 3UAIA 3LWVA 2J5TA 1WXWA 1SGVA 3LWPA 3C0KA 3U28A 4Q1TA 1ZL3A 2B78A 1V9KA
chains in the Genus database with same CATH superfamily
3D79A 1XNEA 2RFKA 1IT7A 3HJYA 2ISTA 1ZE2A 1K8WA 1KSVA 1SZWA 2AB4A 3HJWA 1ZE1A 3ZV0C 2P38A 3LWOA 3HAXA 2AUSA 2EY4A 3MQKA 1KSKA 1PRZA 1WXWA 3C0KA 1UOYA 4Q1TA 1ZL3A 2DP9A 2I82A 2APOA 2Q07A 1TE7A 1SB7A 3IUWA 3LWQA 1Z2ZA 3M65A 3VSEA 1XPIA 1WXXA 3M6XA 1ZS7A 2J5VA 1J2BA 1IT8A 1R3FA 2J5TA 1SGVA 3LWPA 1V9KA 2CX1A 1IQ8A 1T5YA 4LGTA 4LABA 2HVYA 3LJCA 2AS0A 1S04A 1Q7HA 4CI3B 1SI7A 1R3EA 1WK2A 3UAIA 3U28A 2ANEA 2Z0TA 3LDFA 2B78A 3DH3A 3M4XA 2FRXA 4DMGA 3LWRA 2KKUA 2CWWA 1KSLA 4TZ4C 3M6UA 3M6VA 1QYUA 2CX0A 1V9FA 2E5OA 4CI2B 1SQWA 1ZBOA 4CI1B 3LWVA 3M6WA
chains in the Genus database with same CATH topology
3D79A 2I82A 2RFKA 1IT7A 2CX1A 2APOA 1IQ8A 2Q07A 3DH3A 4DMGA 3HJYA 3LWRA 1T5YA 2CWWA 1KSLA 4LGTA 1SB7A 4LABA 2ISTA 1ZE2A 1Z2ZA 1QYUA 1V9FA 2CX0A 3LWQA 2HVYA 1K8WA 3LDFA 3VSEA 1KSVA 1SZWA 1XPIA 2AB4A 1WXXA 2AS0A 3HJWA 1ZE1A 1SQWA 2P38A 3LWOA 1Q7HA 1SI7A 3HAXA 1ZS7A 2J5VA 1R3EA 1J2BA 1KSKA 1PRZA 2AUSA 2EY4A 3MQKA 1IT8A 1R3FA 3UAIA 3LWVA 2J5TA 1WXWA 1SGVA 3LWPA 3C0KA 3U28A 4Q1TA 1ZL3A 2B78A 1V9KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D79 A;  2I82 A;  2RFK A;  1IT7 A;  2CX1 A;  2APO A;  1IQ8 A;  2Q07 A;  3DH3 A;  4DMG A;  3HJY A;  3LWR A;  1T5Y A;  2CWW A;  1KSL A;  4LGT A;  4LAB A;  2IST A;  1ZE2 A;  3LWQ A;  1QYU A;  1V9F A;  2CX0 A;  2HVY A;  1K8W A;  3LDF A;  3VSE A;  1KSV A;  1XPI A;  2AB4 A;  1WXX A;  2AS0 A;  3HJW A;  1ZE1 A;  1SQW A;  2P38 A;  3LWO A;  1Q7H A;  3HAX A;  1ZS7 A;  2J5V A;  1R3E A;  1J2B A;  1KSK A;  1PRZ A;  2AUS A;  2EY4 A;  3MQK A;  1IT8 A;  1R3F A;  3UAI A;  3LWV A;  2J5T A;  1WXW A;  1SGV A;  3LWP A;  3C0K A;  3U28 A;  4Q1T A;  1ZL3 A;  2B78 A;  1V9K A; 
#chains in the Genus database with same CATH topology
 3D79 A;  1XNE A;  2RFK A;  1IT7 A;  3HJY A;  2IST A;  1ZE2 A;  1K8W A;  1KSV A;  1SZW A;  2AB4 A;  3HJW A;  1ZE1 A;  3ZV0 C;  2P38 A;  3LWO A;  3HAX A;  2AUS A;  2EY4 A;  3MQK A;  1KSK A;  1PRZ A;  1WXW A;  3C0K A;  1UOY A;  4Q1T A;  1ZL3 A;  2DP9 A;  2I82 A;  2APO A;  2Q07 A;  1TE7 A;  1SB7 A;  3IUW A;  3LWQ A;  1Z2Z A;  3M65 A;  3VSE A;  1XPI A;  1WXX A;  3M6X A;  1ZS7 A;  2J5V A;  1J2B A;  1IT8 A;  1R3F A;  2J5T A;  1SGV A;  3LWP A;  1V9K A;  2CX1 A;  1IQ8 A;  1T5Y A;  4LGT A;  4LAB A;  2HVY A;  3LJC A;  2AS0 A;  1S04 A;  1Q7H A;  4CI3 B;  1SI7 A;  1R3E A;  1WK2 A;  3UAI A;  3U28 A;  2ANE A;  2Z0T A;  3LDF A;  2B78 A;  3DH3 A;  3M4X A;  2FRX A;  4DMG A;  3LWR A;  2KKU A;  2CWW A;  1KSL A;  4TZ4 C;  3M6U A;  3M6V A;  1QYU A;  2CX0 A;  1V9F A;  2E5O A;  4CI2 B;  1SQW A;  1ZBO A;  4CI1 B;  3LWV A;  3M6W A; 
#chains in the Genus database with same CATH homology
 3D79 A;  2I82 A;  2RFK A;  1IT7 A;  2CX1 A;  2APO A;  1IQ8 A;  2Q07 A;  3DH3 A;  4DMG A;  3HJY A;  3LWR A;  1T5Y A;  2CWW A;  1KSL A;  4LGT A;  1SB7 A;  4LAB A;  2IST A;  1ZE2 A;  1Z2Z A;  1QYU A;  1V9F A;  2CX0 A;  3LWQ A;  2HVY A;  1K8W A;  3LDF A;  3VSE A;  1KSV A;  1SZW A;  1XPI A;  2AB4 A;  1WXX A;  2AS0 A;  3HJW A;  1ZE1 A;  1SQW A;  2P38 A;  3LWO A;  1Q7H A;  1SI7 A;  3HAX A;  1ZS7 A;  2J5V A;  1R3E A;  1J2B A;  1KSK A;  1PRZ A;  2AUS A;  2EY4 A;  3MQK A;  1IT8 A;  1R3F A;  3UAI A;  3LWV A;  2J5T A;  1WXW A;  1SGV A;  3LWP A;  3C0K A;  3U28 A;  4Q1T A;  1ZL3 A;  2B78 A;  1V9K A; 
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