1ZE2 | Genus

Total Genus 75

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	75
sequence length	308
structure length	300
Chain Sequence	MKHGILVAYKPKGPTSHDVVDEVRKKLKTRKVGHGGTLDPFACGVLIIGVNQGTRILEFYKDLKKVYWVKMRLGLITETFDITGEVVEERECNVTEEEIREAIFSFVGEYDQVPPAYSAKKYKGERLYKLAREGKIINLPPKRVKIFKIWDVNIEGRDVSFRVEVSPGTYIRSLCMDIGYKLGCGATAVELVRESVGPHTIEESLNVFEAAPEEIENRIIPLEKCLEWLPRVVVHQESTKMILNGSQIHLEMLKEWDGFKKGEVVRVFNEEGRLLALAEAERNSSFRQERVLTLRKVFQT

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 300 atoms

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase/rna
source organism	Thermotoga maritima
publication title	Conformational change of pseudouridine 55 synthase upon its association with RNA substrate pubmed doi rcsb
molecule keywords	5'-R(GPGPCPCPAPCPGPGPUP(FHU)PCPGPAPAPUPCP*CP
total genus	75
structure length	300
sequence length	308
chains with identical sequence	B
ec nomenclature	ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date	2005-04-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01472	PUA	PUA domain
A	PF01509	TruB_N	TruB family pseudouridylate synthase (N terminal domain)
A	PF16198	TruB_C_2	tRNA pseudouridylate synthase B C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.130.10	Mainly Beta	Roll	Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4	PUA domain	1ze2A02
3.30.2350.10	Alpha Beta	2-Layer Sandwich	Pseudouridine synthase	Pseudouridine synthase	1ze2A01

3LWOA 3LWVA 1WXXA 3HAXA 1PRZA 2CX0A 2B78A 1SQWA 1IT8A 1ZL3A 1KSKA 1WXWA 2Q07A 1R3FA 2AUSA 3HJYA 1T5YA 3C0KA 3LDFA 2HVYA 1SGVA 1V9FA 1Q7HA 2CWWA 3D79A 1ZE2A 3LWRA 3LWPA 1KSLA 2J5TA 4Q1TA 3U28A 2RFKA 1IT7A 3HJWA 2J5VA 3LWQA 2P38A 2AB4A 2CX1A 2APOA 1KSVA 3UAIA 2ISTA 4LABA 1QYUA 3DH3A 2I82A 3MQKA 1ZE1A 3VSEA 1J2BA 4LGTA 1IQ8A 1ZS7A 2EY4A 2AS0A 1R3EA 1V9KA 1K8WA 1XPIA 4DMGA
chains in the Genus database with same CATH superfamily

3LJCA 1S04A 3M6WA 1WXWA 2Q07A 1T5YA 3M65A 3U28A 3M6VA 3HJWA 2APOA 3MQKA 1QYUA 2KKUA 1J2BA 1R3EA 4DMGA 2Z0TA 2CX0A 2AUSA 1UOYA 3C0KA 2HVYA 1V9FA 1KSLA 3M6XA 2J5VA 2ISTA 1KSVA 3DH3A 3ZV0C 4CI2B 1ZS7A 3M4XA 1TE7A 1V9KA 1XPIA 3LWVA 3M6UA 1WXXA 3IUWA 2B78A 1WK2A 1R3FA 1SZWA 1SGVA 1SB7A 1Q7HA 2CWWA 3D79A 1ZE2A 2J5TA 2E5OA 2RFKA 1ZBOA 3LWQA 2AB4A 4LABA 2I82A 3UAIA 4LGTA 2FRXA 2AS0A 1K8WA 3LWOA 3HAXA 1PRZA 1SQWA 3HJYA 1IT8A 1ZL3A 1KSKA 2DP9A 3LDFA 2ANEA 1SI7A 3LWRA 3LWPA 4CI3B 4Q1TA 1IT7A 1XNEA 2P38A 2CX1A 1ZE1A 4TZ4C 3VSEA 4CI1B 1IQ8A 2EY4A 1Z2ZA
chains in the Genus database with same CATH topology

3LWOA 3LWVA 1WXXA 3HAXA 1PRZA 2CX0A 2B78A 1SQWA 1IT8A 1ZL3A 1KSKA 1WXWA 2Q07A 1R3FA 2AUSA 3HJYA 1T5YA 3C0KA 3LDFA 1SZWA 2HVYA 1SGVA 1V9FA 1SB7A 1Q7HA 2CWWA 1SI7A 3D79A 1ZE2A 3LWRA 3LWPA 1KSLA 2J5TA 4Q1TA 3U28A 2RFKA 1IT7A 3HJWA 2J5VA 3LWQA 2P38A 2AB4A 2CX1A 2APOA 1KSVA 3UAIA 2ISTA 4LABA 1QYUA 3DH3A 2I82A 3MQKA 1ZE1A 3VSEA 1J2BA 4LGTA 1IQ8A 1ZS7A 2EY4A 2AS0A 1R3EA 1V9KA 1Z2ZA 1K8WA 1XPIA 4DMGA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3LWO A;  3LWV A;  1WXX A;  3HAX A;  1PRZ A;  2CX0 A;  2B78 A;  1SQW A;  1IT8 A;  1ZL3 A;  1KSK A;  1WXW A;  2Q07 A;  1R3F A;  2AUS A;  3HJY A;  1T5Y A;  3C0K A;  3LDF A;  2HVY A;  1SGV A;  1V9F A;  1Q7H A;  2CWW A;  3D79 A;  1ZE2 A;  3LWR A;  3LWP A;  1KSL A;  2J5T A;  4Q1T A;  3U28 A;  2RFK A;  1IT7 A;  3HJW A;  2J5V A;  3LWQ A;  2P38 A;  2AB4 A;  2CX1 A;  2APO A;  1KSV A;  3UAI A;  2IST A;  4LAB A;  1QYU A;  3DH3 A;  2I82 A;  3MQK A;  1ZE1 A;  3VSE A;  1J2B A;  4LGT A;  1IQ8 A;  1ZS7 A;  2EY4 A;  2AS0 A;  1R3E A;  1V9K A;  1K8W A;  1XPI A;  4DMG A; 
#chains in the Genus database with same CATH topology
 3LJC A;  1S04 A;  3M6W A;  1WXW A;  2Q07 A;  1T5Y A;  3M65 A;  3U28 A;  3M6V A;  3HJW A;  2APO A;  3MQK A;  1QYU A;  2KKU A;  1J2B A;  1R3E A;  4DMG A;  2Z0T A;  2CX0 A;  2AUS A;  1UOY A;  3C0K A;  2HVY A;  1V9F A;  1KSL A;  3M6X A;  2J5V A;  2IST A;  1KSV A;  3DH3 A;  3ZV0 C;  4CI2 B;  1ZS7 A;  3M4X A;  1TE7 A;  1V9K A;  1XPI A;  3LWV A;  3M6U A;  1WXX A;  3IUW A;  2B78 A;  1WK2 A;  1R3F A;  1SZW A;  1SGV A;  1SB7 A;  1Q7H A;  2CWW A;  3D79 A;  1ZE2 A;  2J5T A;  2E5O A;  2RFK A;  1ZBO A;  3LWQ A;  2AB4 A;  4LAB A;  2I82 A;  3UAI A;  4LGT A;  2FRX A;  2AS0 A;  1K8W A;  3LWO A;  3HAX A;  1PRZ A;  1SQW A;  3HJY A;  1IT8 A;  1ZL3 A;  1KSK A;  2DP9 A;  3LDF A;  2ANE A;  1SI7 A;  3LWR A;  3LWP A;  4CI3 B;  4Q1T A;  1IT7 A;  1XNE A;  2P38 A;  2CX1 A;  1ZE1 A;  4TZ4 C;  3VSE A;  4CI1 B;  1IQ8 A;  2EY4 A;  1Z2Z A; 
#chains in the Genus database with same CATH homology
 3LWO A;  3LWV A;  1WXX A;  3HAX A;  1PRZ A;  2CX0 A;  2B78 A;  1SQW A;  1IT8 A;  1ZL3 A;  1KSK A;  1WXW A;  2Q07 A;  1R3F A;  2AUS A;  3HJY A;  1T5Y A;  3C0K A;  3LDF A;  1SZW A;  2HVY A;  1SGV A;  1V9F A;  1SB7 A;  1Q7H A;  2CWW A;  1SI7 A;  3D79 A;  1ZE2 A;  3LWR A;  3LWP A;  1KSL A;  2J5T A;  4Q1T A;  3U28 A;  2RFK A;  1IT7 A;  3HJW A;  2J5V A;  3LWQ A;  2P38 A;  2AB4 A;  2CX1 A;  2APO A;  1KSV A;  3UAI A;  2IST A;  4LAB A;  1QYU A;  3DH3 A;  2I82 A;  3MQK A;  1ZE1 A;  3VSE A;  1J2B A;  4LGT A;  1IQ8 A;  1ZS7 A;  2EY4 A;  2AS0 A;  1R3E A;  1V9K A;  1Z2Z A;  1K8W A;  1XPI A;  4DMG A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1ZE2A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations