2AUS | Genus

Total Genus 85

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	85
sequence length	323
structure length	309
Chain Sequence	ADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 309 atoms

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1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

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309 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Isomerase/structural protein
source organism	Pyrococcus abyssi
publication title	Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity pubmed doi rcsb
molecule keywords	pseudouridine synthase
total genus	85
structure length	309
sequence length	323
chains with identical sequence	C
ec nomenclature	ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date	2005-08-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01472	PUA	PUA domain
A	PF01509	TruB_N	TruB family pseudouridylate synthase (N terminal domain)
A	PF08068	DKCLD	DKCLD (NUC011) domain
A	PF16198	TruB_C_2	tRNA pseudouridylate synthase B C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.130.70	Mainly Beta	Roll	Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4	Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4	2ausA01
3.30.2350.10	Alpha Beta	2-Layer Sandwich	Pseudouridine synthase	Pseudouridine synthase	2ausA02

2RFKA 3UAIA 2HVYA 3U28A 1KSVA 1XPIA 3LWOA 1ZE1A 3LWVA 3HAXA 1KSLA 1R3FA 1ZE2A 4LABA 3HJWA 2AB4A 1PRZA 3LWQA 1KSKA 3MQKA 3ZV0C 3HJYA 2EY4A 1QYUA 2ISTA 4LGTA 2APOA 1K8WA 3LWPA 2I82A 2AUSA 1V9KA 3DH3A 1ZL3A 1R3EA 1V9FA 1SGVA 3LWRA
chains in the Genus database with same CATH superfamily

3D79A 2RFKA 3U28A 2FRXA 1J2BA 3LWVA 1ZE2A 2AS0A 1IT7A 1TE7A 2B78A 3M6VA 3M4XA 3HJWA 1PRZA 2Q07A 1ZS7A 1KSKA 1QYUA 1WXXA 2ISTA 4DMGA 4CI3B 1WXWA 1K8WA 4CI2B 1S04A 2AUSA 3IUWA 1V9FA 3LDFA 2DP9A 1ZE1A 2HVYA 1KSVA 1XPIA 1ZBOA 3HAXA 1R3FA 2J5VA 4LABA 2EY4A 2CX1A 4LGTA 2APOA 1T5YA 1WK2A 1SQWA 1ZL3A 1SGVA 4CI1B 3UAIA 3M65A 2CX0A 3LWOA 1KSLA 1SZWA 1IQ8A 1Z2ZA 2AB4A 3LWQA 3ZV0C 3HJYA 1SB7A 2CWWA 3M6UA 1Q7HA 3LJCA 4TZ4C 2ANEA 3LWPA 2P38A 2I82A 1UOYA 3M6WA 1IT8A 3M6XA 2J5TA 2Z0TA 3MQKA 4Q1TA 3VSEA 1SI7A 1XNEA 1V9KA 3C0KA 2KKUA 3DH3A 2E5OA 1R3EA 3LWRA
chains in the Genus database with same CATH topology

1UOYA 2RFKA 3UAIA 2HVYA 3U28A 1KSVA 2FRXA 3M6WA 3LWOA 1XPIA 3LWVA 1ZE1A 3HAXA 1KSLA 1R3FA 1ZE2A 3M6XA 1SZWA 1Z2ZA 3M6VA 3M4XA 4LABA 3HJWA 2AB4A 1PRZA 3LWQA 1KSKA 3ZV0C 3MQKA 3HJYA 1SB7A 2EY4A 3M6UA 1QYUA 2ISTA 4LGTA 2APOA 1K8WA 1SI7A 3LWPA 2I82A 2AUSA 1V9KA 3DH3A 1ZL3A 1R3EA 1V9FA 1SGVA 3LWRA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2RFK A;  3UAI A;  2HVY A;  3U28 A;  1KSV A;  1XPI A;  3LWO A;  1ZE1 A;  3LWV A;  3HAX A;  1KSL A;  1R3F A;  1ZE2 A;  4LAB A;  3HJW A;  2AB4 A;  1PRZ A;  3LWQ A;  1KSK A;  3MQK A;  3ZV0 C;  3HJY A;  2EY4 A;  1QYU A;  2IST A;  4LGT A;  2APO A;  1K8W A;  3LWP A;  2I82 A;  2AUS A;  1V9K A;  3DH3 A;  1ZL3 A;  1R3E A;  1V9F A;  1SGV A;  3LWR A; 
#chains in the Genus database with same CATH topology
 3D79 A;  2RFK A;  3U28 A;  2FRX A;  1J2B A;  3LWV A;  1ZE2 A;  2AS0 A;  1IT7 A;  1TE7 A;  2B78 A;  3M6V A;  3M4X A;  3HJW A;  1PRZ A;  2Q07 A;  1ZS7 A;  1KSK A;  1QYU A;  1WXX A;  2IST A;  4DMG A;  4CI3 B;  1WXW A;  1K8W A;  4CI2 B;  1S04 A;  2AUS A;  3IUW A;  1V9F A;  3LDF A;  2DP9 A;  1ZE1 A;  2HVY A;  1KSV A;  1XPI A;  1ZBO A;  3HAX A;  1R3F A;  2J5V A;  4LAB A;  2EY4 A;  2CX1 A;  4LGT A;  2APO A;  1T5Y A;  1WK2 A;  1SQW A;  1ZL3 A;  1SGV A;  4CI1 B;  3UAI A;  3M65 A;  2CX0 A;  3LWO A;  1KSL A;  1SZW A;  1IQ8 A;  1Z2Z A;  2AB4 A;  3LWQ A;  3ZV0 C;  3HJY A;  1SB7 A;  2CWW A;  3M6U A;  1Q7H A;  3LJC A;  4TZ4 C;  2ANE A;  3LWP A;  2P38 A;  2I82 A;  1UOY A;  3M6W A;  1IT8 A;  3M6X A;  2J5T A;  2Z0T A;  3MQK A;  4Q1T A;  3VSE A;  1SI7 A;  1XNE A;  1V9K A;  3C0K A;  2KKU A;  3DH3 A;  2E5O A;  1R3E A;  3LWR A; 
#chains in the Genus database with same CATH homology
 1UOY A;  2RFK A;  3UAI A;  2HVY A;  3U28 A;  1KSV A;  2FRX A;  3M6W A;  3LWO A;  1XPI A;  3LWV A;  1ZE1 A;  3HAX A;  1KSL A;  1R3F A;  1ZE2 A;  3M6X A;  1SZW A;  1Z2Z A;  3M6V A;  3M4X A;  4LAB A;  3HJW A;  2AB4 A;  1PRZ A;  3LWQ A;  1KSK A;  3ZV0 C;  3MQK A;  3HJY A;  1SB7 A;  2EY4 A;  3M6U A;  1QYU A;  2IST A;  4LGT A;  2APO A;  1K8W A;  1SI7 A;  3LWP A;  2I82 A;  2AUS A;  1V9K A;  3DH3 A;  1ZL3 A;  1R3E A;  1V9F A;  1SGV A;  3LWR A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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2AUSA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations