2AUSA

Crystal structure of the archaeal box h/aca srnp nop10-cbf5 complex
Total Genus 85
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
323
structure length
309
Chain Sequence
ADIKREVIVKDDKAETNPKWGFPPDKRPIELHIQYGVINLDKPPGPTSHEVVAWIKRILNLEKAGHGGTLDPKVSGVLPVALERATRVVQALLPAGKEYVALMHLHGDVPEDKIRAVMKEFEGEIIQRKVYYIEILEIDGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMAELRRTRSGPFKEDETLVTLHDLVDYYHFWKEDGIEEYIRKAIQPMEKAVEHLPKIWIKDSAVAAVAHGANLTVPGIVKLNAGIKKGDLVAIMTLKDELVALGKAMMSTQEMIERSKGIAVDVEKVFMPRDWYPKLW
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure determination and site-directed mutagenesis of the Pyrococcus abyssi aCBF5-aNOP10 complex reveal crucial roles of the C-terminal domains of both proteins in H/ACA sRNP activity
pubmed doi rcsb
molecule tags Isomerase/structural protein
source organism Pyrococcus abyssi
molecule keywords pseudouridine synthase
total genus 85
structure length 309
sequence length 323
chains with identical sequence C
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2005-08-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 2ausA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2ausA02
3HAXA 2I82A 2AUSA 3HJWA 2APOA 1R3EA 4LGTA 1V9KA 3LWOA 1PRZA 1ZE1A 3DH3A 3LWVA 1KSKA 3HJYA 1K8WA 2RFKA 2AB4A 1ZL3A 1R3FA 2HVYA 3ZV0C 3LWRA 3MQKA 3UAIA 4LABA 2EY4A 1XPIA 1V9FA 1SGVA 3U28A 3LWPA 1ZE2A 1QYUA 2ISTA 1KSVA 3LWQA 1KSLA
chains in the Genus database with same CATH superfamily
2I82A 3M6UA 2J5TA 1KSKA 1ZS7A 1ZL3A 4CI3B 3MQKA 4CI2B 2CWWA 2EY4A 4TZ4C 3LJCA 1QYUA 1J2BA 1R3FA 2CX0A 3LWQA 1KSLA 1S04A 3HJWA 1WK2A 2KKUA 1V9KA 1K8WA 3HJYA 2AB4A 2DP9A 1XNEA 1UOYA 2E5OA 3C0KA 2P38A 1SGVA 3VSEA 3M6XA 2ISTA 4DMGA 1KSVA 1WXXA 2Q07A 4CI1B 3HAXA 3M6VA 4Q1TA 2AUSA 2B78A 1Q7HA 3DH3A 3ZV0C 1SB7A 1XPIA 1T5YA 3LWPA 2Z0TA 1ZE2A 3LDFA 1Z2ZA 2J5VA 2ANEA 1ZBOA 2APOA 2FRXA 1R3EA 4LGTA 2CX1A 3LWOA 1PRZA 1ZE1A 1IT7A 3LWVA 1IT8A 3M4XA 2RFKA 3IUWA 2HVYA 3LWRA 3UAIA 4LABA 1SZWA 1SI7A 1SQWA 3M65A 1WXWA 3D79A 1V9FA 3U28A 1TE7A 2AS0A 1IQ8A 3M6WA
chains in the Genus database with same CATH topology
3HAXA 3M6VA 2I82A 2AUSA 3HJWA 2APOA 2FRXA 4LGTA 1R3EA 1V9KA 3LWOA 1PRZA 1ZE1A 3DH3A 3LWVA 3M6UA 1KSKA 3HJYA 1K8WA 3M4XA 2RFKA 2AB4A 1ZL3A 1R3FA 2HVYA 3ZV0C 3LWRA 3MQKA 3UAIA 4LABA 1SZWA 1SI7A 1SB7A 1KSVA 1UOYA 2EY4A 1XPIA 1V9FA 1SGVA 3U28A 3LWPA 1ZE2A 1QYUA 1Z2ZA 3M6XA 2ISTA 3M6WA 3LWQA 1KSLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HAX A;  2I82 A;  2AUS A;  3HJW A;  2APO A;  1R3E A;  4LGT A;  1V9K A;  3LWO A;  1PRZ A;  1ZE1 A;  3DH3 A;  3LWV A;  1KSK A;  3HJY A;  1K8W A;  2RFK A;  2AB4 A;  1ZL3 A;  1R3F A;  2HVY A;  3ZV0 C;  3LWR A;  3MQK A;  3UAI A;  4LAB A;  2EY4 A;  1XPI A;  1V9F A;  1SGV A;  3U28 A;  3LWP A;  1ZE2 A;  1QYU A;  2IST A;  1KSV A;  3LWQ A;  1KSL A; 
#chains in the Genus database with same CATH topology
 2I82 A;  3M6U A;  2J5T A;  1KSK A;  1ZS7 A;  1ZL3 A;  4CI3 B;  3MQK A;  4CI2 B;  2CWW A;  2EY4 A;  4TZ4 C;  3LJC A;  1QYU A;  1J2B A;  1R3F A;  2CX0 A;  3LWQ A;  1KSL A;  1S04 A;  3HJW A;  1WK2 A;  2KKU A;  1V9K A;  1K8W A;  3HJY A;  2AB4 A;  2DP9 A;  1XNE A;  1UOY A;  2E5O A;  3C0K A;  2P38 A;  1SGV A;  3VSE A;  3M6X A;  2IST A;  4DMG A;  1KSV A;  1WXX A;  2Q07 A;  4CI1 B;  3HAX A;  3M6V A;  4Q1T A;  2AUS A;  2B78 A;  1Q7H A;  3DH3 A;  3ZV0 C;  1SB7 A;  1XPI A;  1T5Y A;  3LWP A;  2Z0T A;  1ZE2 A;  3LDF A;  1Z2Z A;  2J5V A;  2ANE A;  1ZBO A;  2APO A;  2FRX A;  1R3E A;  4LGT A;  2CX1 A;  3LWO A;  1PRZ A;  1ZE1 A;  1IT7 A;  3LWV A;  1IT8 A;  3M4X A;  2RFK A;  3IUW A;  2HVY A;  3LWR A;  3UAI A;  4LAB A;  1SZW A;  1SI7 A;  1SQW A;  3M65 A;  1WXW A;  3D79 A;  1V9F A;  3U28 A;  1TE7 A;  2AS0 A;  1IQ8 A;  3M6W A; 
#chains in the Genus database with same CATH homology
 3HAX A;  3M6V A;  2I82 A;  2AUS A;  3HJW A;  2APO A;  2FRX A;  4LGT A;  1R3E A;  1V9K A;  3LWO A;  1PRZ A;  1ZE1 A;  3DH3 A;  3LWV A;  3M6U A;  1KSK A;  3HJY A;  1K8W A;  3M4X A;  2RFK A;  2AB4 A;  1ZL3 A;  1R3F A;  2HVY A;  3ZV0 C;  3LWR A;  3MQK A;  3UAI A;  4LAB A;  1SZW A;  1SI7 A;  1SB7 A;  1KSV A;  1UOY A;  2EY4 A;  1XPI A;  1V9F A;  1SGV A;  3U28 A;  3LWP A;  1ZE2 A;  1QYU A;  1Z2Z A;  3M6X A;  2IST A;  3M6W A;  3LWQ A;  1KSL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...