2HVYA

Crystal structure of an h/aca box rnp from pyrococcus furiosus
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
327
structure length
320
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of an H/ACA box ribonucleoprotein particle
pubmed doi rcsb
molecule tags Isomerase/biosynthetic protein/rna
source organism Pyrococcus furiosus
molecule keywords H/ACA RNA
total genus 90
structure length 320
sequence length 327
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2006-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 2hvyA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2hvyA02
3LWVA 2ISTA 4LGTA 2APOA 1KSVA 1R3FA 1ZL3A 1V9FA 1PRZA 3UAIA 1QYUA 3ZV0C 3LWQA 2AB4A 3HJYA 1ZE2A 3LWRA 1KSLA 1XPIA 1SGVA 2EY4A 2HVYA 3LWOA 3DH3A 3U28A 4LABA 2I82A 2RFKA 1KSKA 1R3EA 2AUSA 3MQKA 3HAXA 1V9KA 3LWPA 1K8WA 1ZE1A 3HJWA
chains in the Genus database with same CATH superfamily
4Q1TA 2APOA 1PRZA 2Z0TA 3LDFA 3C0KA 3M65A 1ZE2A 1Q7HA 3LWRA 2B78A 2Q07A 1WXWA 2I82A 1WK2A 1ZBOA 3IUWA 2KKUA 2P38A 1SQWA 4DMGA 2CWWA 1SB7A 4CI3B 4CI2B 3M6UA 1R3FA 1ZL3A 1V9FA 3UAIA 3M6WA 2DP9A 1XPIA 2EY4A 2HVYA 1IT7A 1WXXA 2CX1A 1SZWA 3VSEA 2RFKA 3LJCA 2AS0A 2AUSA 3MQKA 3HAXA 2FRXA 3M4XA 2ISTA 4LGTA 4CI1B 2J5TA 3ZV0C 3HJYA 1XNEA 1UOYA 1S04A 3D79A 3LWOA 3U28A 1T5YA 3M6VA 2E5OA 1IT8A 3LWPA 1K8WA 1ZE1A 3LWVA 1SI7A 1ZS7A 1J2BA 1KSVA 1QYUA 4TZ4C 1Z2ZA 3LWQA 2AB4A 1KSLA 1SGVA 1IQ8A 3DH3A 2J5VA 1TE7A 4LABA 2ANEA 1KSKA 1R3EA 1V9KA 2CX0A 3M6XA 3HJWA
chains in the Genus database with same CATH topology
3LWVA 1SB7A 2ISTA 1SI7A 3M6UA 4LGTA 2APOA 1KSVA 1R3FA 1ZL3A 1V9FA 1PRZA 3UAIA 3M6WA 1QYUA 3ZV0C 1Z2ZA 3LWQA 2AB4A 3HJYA 1ZE2A 3LWRA 1KSLA 1UOYA 1XPIA 1SGVA 2EY4A 2HVYA 3LWOA 3DH3A 3U28A 4LABA 1K8WA 1SZWA 2I82A 3M6VA 2RFKA 1KSKA 1R3EA 2AUSA 3MQKA 3HAXA 1V9KA 3M6XA 3LWPA 2FRXA 1ZE1A 3M4XA 3HJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LWV A;  2IST A;  4LGT A;  2APO A;  1KSV A;  1R3F A;  1ZL3 A;  1V9F A;  1PRZ A;  3UAI A;  1QYU A;  3ZV0 C;  3LWQ A;  2AB4 A;  3HJY A;  1ZE2 A;  3LWR A;  1KSL A;  1XPI A;  1SGV A;  2EY4 A;  2HVY A;  3LWO A;  3DH3 A;  3U28 A;  4LAB A;  2I82 A;  2RFK A;  1KSK A;  1R3E A;  2AUS A;  3MQK A;  3HAX A;  1V9K A;  3LWP A;  1K8W A;  1ZE1 A;  3HJW A; 
#chains in the Genus database with same CATH topology
 4Q1T A;  2APO A;  1PRZ A;  2Z0T A;  3LDF A;  3C0K A;  3M65 A;  1ZE2 A;  1Q7H A;  3LWR A;  2B78 A;  2Q07 A;  1WXW A;  2I82 A;  1WK2 A;  1ZBO A;  3IUW A;  2KKU A;  2P38 A;  1SQW A;  4DMG A;  2CWW A;  1SB7 A;  4CI3 B;  4CI2 B;  3M6U A;  1R3F A;  1ZL3 A;  1V9F A;  3UAI A;  3M6W A;  2DP9 A;  1XPI A;  2EY4 A;  2HVY A;  1IT7 A;  1WXX A;  2CX1 A;  1SZW A;  3VSE A;  2RFK A;  3LJC A;  2AS0 A;  2AUS A;  3MQK A;  3HAX A;  2FRX A;  3M4X A;  2IST A;  4LGT A;  4CI1 B;  2J5T A;  3ZV0 C;  3HJY A;  1XNE A;  1UOY A;  1S04 A;  3D79 A;  3LWO A;  3U28 A;  1T5Y A;  3M6V A;  2E5O A;  1IT8 A;  3LWP A;  1K8W A;  1ZE1 A;  3LWV A;  1SI7 A;  1ZS7 A;  1J2B A;  1KSV A;  1QYU A;  4TZ4 C;  1Z2Z A;  3LWQ A;  2AB4 A;  1KSL A;  1SGV A;  1IQ8 A;  3DH3 A;  2J5V A;  1TE7 A;  4LAB A;  2ANE A;  1KSK A;  1R3E A;  1V9K A;  2CX0 A;  3M6X A;  3HJW A; 
#chains in the Genus database with same CATH homology
 3LWV A;  1SB7 A;  2IST A;  1SI7 A;  3M6U A;  4LGT A;  2APO A;  1KSV A;  1R3F A;  1ZL3 A;  1V9F A;  1PRZ A;  3UAI A;  3M6W A;  1QYU A;  3ZV0 C;  1Z2Z A;  3LWQ A;  2AB4 A;  3HJY A;  1ZE2 A;  3LWR A;  1KSL A;  1UOY A;  1XPI A;  1SGV A;  2EY4 A;  2HVY A;  3LWO A;  3DH3 A;  3U28 A;  4LAB A;  1K8W A;  1SZW A;  2I82 A;  3M6V A;  2RFK A;  1KSK A;  1R3E A;  2AUS A;  3MQK A;  3HAX A;  1V9K A;  3M6X A;  3LWP A;  2FRX A;  1ZE1 A;  3M4X A;  3HJW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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