2Q18X

2-keto-3-deoxy-d-arabinonate dehydratase
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
291
structure length
282
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Sulfolobus solfataricus
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 82
structure length 282
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q18X01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q18X02
3LZKA 1WZOA 2Q1AX 5D2KA 2HZYA 3BQBA 2EB5A 4PFZA 5D2GA 4QKUA 1SAWA 1QCOA 2Q1DX 2WQTA 2EB4A 2Q1CX 3R6OA 1QQJA 1HYOA 5D2FA 3V77A 1SV6A 4DBFA 1I7OA 1GTTA 4MAQA 1NKQA 5D2HA 2Q19X 2Q18X 5D2IA 2EB6A 3S52A 2DFUA 4DBHA 1NR9A 5D2JA 3RR6A 1QCNA 3QDFA
chains in the Genus database with same CATH superfamily
4AS1A 3CF2A 1O54A 5DYIA 5D2GA 4KO8A 2Q1DX 2Q1CX 5ERGB 5FTLA 2YVLA 1HYOA 5CCBA 1QQJA 4AQ7A 5D6WA 5FTMA 3QC8A 1S3SA 2GFAA 4MAQA 3HU2A 2Q19X 4ARCA 2GF7A 3FPTA 4KODA 2DFUA 4RV0A 1NR9A 3LZKA 1WZOA 2QQSA 2JV2A 1R7RA 1CR5A 3MB5A 3BQBA 1E32A 5FTJA 4PFZA 2LW6A 4QKUA 2XDPA 2EB4A 5D6XA 5CCXA 3ZJUA 4KDIA 4UC4A 5D6YA 1CZ4A 5CD1A 1GTTA 5C1BA 3ZJTA 1WLFA 3ZGZA 1CZ5A 3RR6A 3ZJVA 1ZC1A 4KDLA 3LHDA 5D2KA 2EB5A 2YUJA 3FPUA 4KLNA 1QCOA 1SAWA 2WQTA 2KY9A 3QWZA 3FPRA 3R6OA 4FIBA 5D2FA 2PWYA 5B6CA 1I7OA 3QQ7A 1NKQA 5DYGA 4ARIA 5FTKA 5D2IA 1I9GA 2MM0A 3TIWA 5FTNA 1QCNA 3QDFA 2Q1AX 3HU3A 5GLFA 1QDNA 2HZYA 4CQNA 1QCSA 5EQJB 2QQRA 2MM2A 3QQ8A 2B25A 5C18A 3V77A 3LGAA 1SV6A 3HU1A 5EPPA 5D2HA 2Q18X 2PJHB 2EB6A 3S52A 4DBHA 5D2JA 4DBFA
chains in the Genus database with same CATH topology
4AS1A 3CF2A 1O54A 5DYIA 5D2GA 4KO8A 2Q1DX 2Q1CX 5ERGB 5FTLA 2YVLA 1HYOA 5CCBA 1QQJA 4AQ7A 5D6WA 5FTMA 3QC8A 1S3SA 2GFAA 4MAQA 3HU2A 2Q19X 4ARCA 2GF7A 3FPTA 4KODA 2DFUA 4RV0A 1NR9A 3LZKA 1WZOA 2QQSA 2JV2A 1R7RA 1CR5A 3MB5A 3BQBA 1E32A 5FTJA 4PFZA 2LW6A 4QKUA 2XDPA 2EB4A 5D6XA 5CCXA 3ZJUA 4KDIA 4UC4A 5D6YA 1CZ4A 5CD1A 1GTTA 5C1BA 3ZJTA 1WLFA 3ZGZA 1CZ5A 3RR6A 3ZJVA 1ZC1A 4KDLA 3LHDA 5D2KA 2EB5A 2YUJA 3FPUA 4KLNA 1QCOA 1SAWA 2WQTA 2KY9A 3QWZA 3FPRA 3R6OA 4FIBA 5D2FA 2PWYA 5B6CA 1I7OA 3QQ7A 1NKQA 5DYGA 4ARIA 5FTKA 5D2IA 1I9GA 2MM0A 3TIWA 5FTNA 1QCNA 3QDFA 2Q1AX 3HU3A 5GLFA 1QDNA 2HZYA 4CQNA 1QCSA 5EQJB 2QQRA 2MM2A 3QQ8A 2B25A 5C18A 3V77A 3LGAA 1SV6A 3HU1A 5EPPA 5D2HA 2Q18X 2PJHB 2EB6A 3S52A 4DBHA 5D2JA 4DBFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3LZK A;  1WZO A;  2Q1A X;  5D2K A;  2HZY A;  3BQB A;  2EB5 A;  4PFZ A;  5D2G A;  4QKU A;  1SAW A;  1QCO A;  2Q1D X;  2WQT A;  2EB4 A;  2Q1C X;  3R6O A;  1QQJ A;  1HYO A;  5D2F A;  3V77 A;  1SV6 A;  4DBF A;  1I7O A;  1GTT A;  4MAQ A;  1NKQ A;  5D2H A;  2Q19 X;  2Q18 X;  5D2I A;  2EB6 A;  3S52 A;  2DFU A;  4DBH A;  1NR9 A;  5D2J A;  3RR6 A;  1QCN A;  3QDF A; 
#chains in the Genus database with same CATH topology
 4AS1 A;  3CF2 A;  1O54 A;  5DYI A;  5D2G A;  4KO8 A;  2Q1D X;  2Q1C X;  5ERG B;  5FTL A;  2YVL A;  1HYO A;  5CCB A;  1QQJ A;  4AQ7 A;  5D6W A;  5FTM A;  3QC8 A;  1S3S A;  2GFA A;  4MAQ A;  3HU2 A;  2Q19 X;  4ARC A;  2GF7 A;  3FPT A;  4KOD A;  2DFU A;  4RV0 A;  1NR9 A;  3LZK A;  1WZO A;  2QQS A;  2JV2 A;  1R7R A;  1CR5 A;  3MB5 A;  3BQB A;  1E32 A;  5FTJ A;  4PFZ A;  2LW6 A;  4QKU A;  2XDP A;  2EB4 A;  5D6X A;  5CCX A;  3ZJU A;  4KDI A;  4UC4 A;  5D6Y A;  1CZ4 A;  5CD1 A;  1GTT A;  5C1B A;  3ZJT A;  1WLF A;  3ZGZ A;  1CZ5 A;  3RR6 A;  3ZJV A;  1ZC1 A;  4KDL A;  3LHD A;  5D2K A;  2EB5 A;  2YUJ A;  3FPU A;  4KLN A;  1QCO A;  1SAW A;  2WQT A;  2KY9 A;  3QWZ A;  3FPR A;  3R6O A;  4FIB A;  5D2F A;  2PWY A;  5B6C A;  1I7O A;  3QQ7 A;  1NKQ A;  5DYG A;  4ARI A;  5FTK A;  5D2I A;  1I9G A;  2MM0 A;  3TIW A;  5FTN A;  1QCN A;  3QDF A;  2Q1A X;  3HU3 A;  5GLF A;  1QDN A;  2HZY A;  4CQN A;  1QCS A;  5EQJ B;  2QQR A;  2MM2 A;  3QQ8 A;  2B25 A;  5C18 A;  3V77 A;  3LGA A;  1SV6 A;  3HU1 A;  5EPP A;  5D2H A;  2Q18 X;  2PJH B;  2EB6 A;  3S52 A;  4DBH A;  5D2J A;  4DBF A; 
#chains in the Genus database with same CATH homology
 4AS1 A;  3CF2 A;  1O54 A;  5DYI A;  5D2G A;  4KO8 A;  2Q1D X;  2Q1C X;  5ERG B;  5FTL A;  2YVL A;  1HYO A;  5CCB A;  1QQJ A;  4AQ7 A;  5D6W A;  5FTM A;  3QC8 A;  1S3S A;  2GFA A;  4MAQ A;  3HU2 A;  2Q19 X;  4ARC A;  2GF7 A;  3FPT A;  4KOD A;  2DFU A;  4RV0 A;  1NR9 A;  3LZK A;  1WZO A;  2QQS A;  2JV2 A;  1R7R A;  1CR5 A;  3MB5 A;  3BQB A;  1E32 A;  5FTJ A;  4PFZ A;  2LW6 A;  4QKU A;  2XDP A;  2EB4 A;  5D6X A;  5CCX A;  3ZJU A;  4KDI A;  4UC4 A;  5D6Y A;  1CZ4 A;  5CD1 A;  1GTT A;  5C1B A;  3ZJT A;  1WLF A;  3ZGZ A;  1CZ5 A;  3RR6 A;  3ZJV A;  1ZC1 A;  4KDL A;  3LHD A;  5D2K A;  2EB5 A;  2YUJ A;  3FPU A;  4KLN A;  1QCO A;  1SAW A;  2WQT A;  2KY9 A;  3QWZ A;  3FPR A;  3R6O A;  4FIB A;  5D2F A;  2PWY A;  5B6C A;  1I7O A;  3QQ7 A;  1NKQ A;  5DYG A;  4ARI A;  5FTK A;  5D2I A;  1I9G A;  2MM0 A;  3TIW A;  5FTN A;  1QCN A;  3QDF A;  2Q1A X;  3HU3 A;  5GLF A;  1QDN A;  2HZY A;  4CQN A;  1QCS A;  5EQJ B;  2QQR A;  2MM2 A;  3QQ8 A;  2B25 A;  5C18 A;  3V77 A;  3LGA A;  1SV6 A;  3HU1 A;  5EPP A;  5D2H A;  2Q18 X;  2PJH B;  2EB6 A;  3S52 A;  4DBH A;  5D2J A;  4DBF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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