2Q19 | Genus

Total Genus 76

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	76
sequence length	291
structure length	282
Chain Sequence	MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Sulfolobus solfataricus
publication title	Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily. pubmed doi rcsb
molecule keywords	2-keto-3-deoxy-D-arabinonate dehydratase
total genus	76
structure length	282
sequence length	291
ec nomenclature	ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date	2007-05-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
X	PF01557	FAA_hydrolase	Fumarylacetoacetate (FAA) hydrolase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.330.40	Alpha Beta	Roll	Vcp-like ATPase; Chain A, domain 2	Vcp-like ATPase; Chain A, domain 2	2q19X01
3.90.850.10	Alpha Beta	Alpha-Beta Complex	Fumarylacetoacetate hydrolase; domain 2	Fumarylacetoacetase-like, C-terminal domain	2q19X02

1SV6A 3BQBA 4QKUA 1NR9A 5D2IA 2Q18X 4PFZA 5D2KA 1GTTA 5D2JA 1QQJA 1QCNA 2WQTA 5D2HA 4DBHA 1HYOA 2HZYA 2Q1DX 3QDFA 3V77A 5D2FA 2EB5A 3R6OA 4DBFA 4MAQA 1WZOA 2Q19X 2DFUA 1NKQA 3S52A 1QCOA 2Q1AX 1SAWA 5D2GA 2Q1CX 1I7OA 3LZKA 3RR6A 2EB6A 2EB4A
chains in the Genus database with same CATH superfamily

3QWZA 5GLFA 1NR9A 3QC8A 3FPUA 4FIBA 1QCSA 5D2IA 2Q18X 1O54A 5D2JA 1ZC1A 1QCNA 2WQTA 4DBHA 1HYOA 5FTMA 4ARIA 3MB5A 4AS1A 4MAQA 3FPRA 1WZOA 2Q19X 3S52A 5DYGA 5FTNA 1R7RA 5D2GA 5EQJB 2Q1CX 1I7OA 4KO8A 1SV6A 5CCXA 5D6YA 3HU3A 5D2KA 1GTTA 1QQJA 5B6CA 1E32A 2LW6A 2XDPA 2HZYA 4DBFA 3ZJUA 2JV2A 1QCOA 5D6XA 5CCBA 1I9GA 5D6WA 2GFAA 3TIWA 5EPPA 2EB6A 2GF7A 3ZJVA 4RV0A 2MM2A 3BQBA 4QKUA 5ERGB 2QQRA 4KDLA 4KDIA 3HU1A 2KY9A 5DYIA 4KODA 4CQNA 2YUJA 5D2HA 5C1BA 3ZJTA 4AQ7A 2QQSA 3QDFA 3QQ8A 5D2FA 3V77A 1QDNA 3R6OA 4UC4A 3ZGZA 2PJHB 2Q1AX 1SAWA 5C18A 3RR6A 4KLNA 5FTJA 5FTKA 3LHDA 1CR5A 5CD1A 4PFZA 3CF2A 1CZ4A 2Q1DX 2B25A 5FTLA 1CZ5A 2EB5A 2YVLA 3LGAA 3QQ7A 2DFUA 4ARCA 1NKQA 3HU2A 1WLFA 3FPTA 2MM0A 3LZKA 1S3SA 2EB4A 2PWYA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1SV6 A;  3BQB A;  4QKU A;  1NR9 A;  5D2I A;  2Q18 X;  4PFZ A;  5D2K A;  1GTT A;  5D2J A;  1QQJ A;  1QCN A;  2WQT A;  5D2H A;  4DBH A;  1HYO A;  2HZY A;  2Q1D X;  3QDF A;  3V77 A;  5D2F A;  2EB5 A;  3R6O A;  4DBF A;  4MAQ A;  1WZO A;  2Q19 X;  2DFU A;  1NKQ A;  3S52 A;  1QCO A;  2Q1A X;  1SAW A;  5D2G A;  2Q1C X;  1I7O A;  3LZK A;  3RR6 A;  2EB6 A;  2EB4 A; 
#chains in the Genus database with same CATH topology
 3QWZ A;  5GLF A;  1NR9 A;  3QC8 A;  3FPU A;  4FIB A;  1QCS A;  5D2I A;  2Q18 X;  1O54 A;  5D2J A;  1ZC1 A;  1QCN A;  2WQT A;  4DBH A;  1HYO A;  5FTM A;  4ARI A;  3MB5 A;  4AS1 A;  4MAQ A;  3FPR A;  1WZO A;  2Q19 X;  3S52 A;  5DYG A;  5FTN A;  1R7R A;  5D2G A;  5EQJ B;  2Q1C X;  1I7O A;  4KO8 A;  1SV6 A;  5CCX A;  5D6Y A;  3HU3 A;  5D2K A;  1GTT A;  1QQJ A;  5B6C A;  1E32 A;  2LW6 A;  2XDP A;  2HZY A;  4DBF A;  3ZJU A;  2JV2 A;  1QCO A;  5D6X A;  5CCB A;  1I9G A;  5D6W A;  2GFA A;  3TIW A;  5EPP A;  2EB6 A;  2GF7 A;  3ZJV A;  4RV0 A;  2MM2 A;  3BQB A;  4QKU A;  5ERG B;  2QQR A;  4KDL A;  4KDI A;  3HU1 A;  2KY9 A;  5DYI A;  4KOD A;  4CQN A;  2YUJ A;  5D2H A;  5C1B A;  3ZJT A;  4AQ7 A;  2QQS A;  3QDF A;  3QQ8 A;  5D2F A;  3V77 A;  1QDN A;  3R6O A;  4UC4 A;  3ZGZ A;  2PJH B;  2Q1A X;  1SAW A;  5C18 A;  3RR6 A;  4KLN A;  5FTJ A;  5FTK A;  3LHD A;  1CR5 A;  5CD1 A;  4PFZ A;  3CF2 A;  1CZ4 A;  2Q1D X;  2B25 A;  5FTL A;  1CZ5 A;  2EB5 A;  2YVL A;  3LGA A;  3QQ7 A;  2DFU A;  4ARC A;  1NKQ A;  3HU2 A;  1WLF A;  3FPT A;  2MM0 A;  3LZK A;  1S3S A;  2EB4 A;  2PWY A; 
#chains in the Genus database with same CATH homology
 3QWZ A;  5GLF A;  1NR9 A;  3QC8 A;  3FPU A;  4FIB A;  1QCS A;  5D2I A;  2Q18 X;  1O54 A;  5D2J A;  1ZC1 A;  1QCN A;  2WQT A;  4DBH A;  1HYO A;  5FTM A;  4ARI A;  3MB5 A;  4AS1 A;  4MAQ A;  3FPR A;  1WZO A;  2Q19 X;  3S52 A;  5DYG A;  5FTN A;  1R7R A;  5D2G A;  5EQJ B;  2Q1C X;  1I7O A;  4KO8 A;  1SV6 A;  5CCX A;  5D6Y A;  3HU3 A;  5D2K A;  1GTT A;  1QQJ A;  5B6C A;  1E32 A;  2LW6 A;  2XDP A;  2HZY A;  4DBF A;  3ZJU A;  2JV2 A;  1QCO A;  5D6X A;  5CCB A;  1I9G A;  5D6W A;  2GFA A;  3TIW A;  5EPP A;  2EB6 A;  2GF7 A;  3ZJV A;  4RV0 A;  2MM2 A;  3BQB A;  4QKU A;  5ERG B;  2QQR A;  4KDL A;  4KDI A;  3HU1 A;  2KY9 A;  5DYI A;  4KOD A;  4CQN A;  2YUJ A;  5D2H A;  5C1B A;  3ZJT A;  4AQ7 A;  2QQS A;  3QDF A;  3QQ8 A;  5D2F A;  3V77 A;  1QDN A;  3R6O A;  4UC4 A;  3ZGZ A;  2PJH B;  2Q1A X;  1SAW A;  5C18 A;  3RR6 A;  4KLN A;  5FTJ A;  5FTK A;  3LHD A;  1CR5 A;  5CD1 A;  4PFZ A;  3CF2 A;  1CZ4 A;  2Q1D X;  2B25 A;  5FTL A;  1CZ5 A;  2EB5 A;  2YVL A;  3LGA A;  3QQ7 A;  2DFU A;  4ARC A;  1NKQ A;  3HU2 A;  1WLF A;  3FPT A;  2MM0 A;  3LZK A;  1S3S A;  2EB4 A;  2PWY A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2Q19X

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations