2Q1AX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2-oxobutyrate
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Sulfolobus solfataricus
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 79
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1aX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1aX02
2WQTA 3R6OA 1HYOA 1WZOA 1QQJA 5D2KA 4MAQA 1QCNA 2HZYA 4DBHA 3RR6A 4QKUA 1I7OA 1NKQA 2Q19X 2EB6A 1SAWA 3QDFA 3V77A 5D2HA 2EB5A 2Q1AX 3BQBA 5D2JA 2Q1CX 3LZKA 2DFUA 5D2IA 2Q1DX 1QCOA 5D2FA 5D2GA 3S52A 4DBFA 2Q18X 1NR9A 1GTTA 1SV6A 4PFZA 2EB4A
chains in the Genus database with same CATH superfamily
3QC8A 1WZOA 3QQ7A 2YVLA 2HZYA 5B6CA 3HU3A 3FPUA 2Q19X 5FTMA 2MM2A 3V77A 5EQJB 5D2HA 5CD1A 3HU1A 5D2JA 5DYGA 3FPRA 3ZGZA 4ARCA 1WLFA 4KLNA 2B25A 3R6OA 1CZ5A 1QQJA 1CZ4A 1R7RA 4MAQA 4DBHA 5CCBA 2PJHB 1NKQA 4CQNA 5FTLA 1SAWA 2LW6A 2GFAA 3QDFA 5FTJA 4RV0A 5C18A 5C1BA 5D6YA 5D2GA 3MB5A 3ZJTA 5ERGB 1I9GA 1I7OA 2WQTA 2EB4A 1ZC1A 2GF7A 5D2KA 5DYIA 4KDLA 3ZJVA 3RR6A 4QKUA 3QWZA 3ZJUA 4FIBA 5FTNA 4AQ7A 2EB6A 3FPTA 4KODA 1E32A 2KY9A 3TIWA 1S3SA 5D6WA 2DFUA 2MM0A 5FTKA 1O54A 1NR9A 1GTTA 4UC4A 1SV6A 4PFZA 5D2FA 2YUJA 3HU2A 1HYOA 5EPPA 2XDPA 1CR5A 4KO8A 3CF2A 1QCNA 4AS1A 2PWYA 5D6XA 3LGAA 3LHDA 5GLFA 4ARIA 1QCSA 4KDIA 2EB5A 2JV2A 2Q1AX 3BQBA 2Q1CX 3LZKA 5D2IA 2Q1DX 3QQ8A 3S52A 4DBFA 1QDNA 2Q18X 2QQRA 1QCOA 2QQSA 5CCXA
chains in the Genus database with same CATH topology
3QC8A 1WZOA 3QQ7A 2YVLA 2HZYA 5B6CA 3HU3A 3FPUA 2Q19X 5FTMA 2MM2A 3V77A 5EQJB 5D2HA 5CD1A 3HU1A 5D2JA 5DYGA 3FPRA 3ZGZA 4ARCA 1WLFA 4KLNA 2B25A 3R6OA 1CZ5A 1QQJA 1CZ4A 1R7RA 4MAQA 4DBHA 5CCBA 2PJHB 1NKQA 4CQNA 5FTLA 1SAWA 2LW6A 2GFAA 3QDFA 5FTJA 4RV0A 5C18A 5C1BA 5D6YA 5D2GA 3MB5A 3ZJTA 5ERGB 1I9GA 1I7OA 2WQTA 2EB4A 1ZC1A 2GF7A 5D2KA 5DYIA 4KDLA 3ZJVA 3RR6A 4QKUA 3QWZA 3ZJUA 4FIBA 5FTNA 4AQ7A 2EB6A 3FPTA 4KODA 1E32A 2KY9A 3TIWA 1S3SA 5D6WA 2DFUA 2MM0A 5FTKA 1O54A 1NR9A 1GTTA 4UC4A 1SV6A 4PFZA 5D2FA 2YUJA 3HU2A 1HYOA 5EPPA 2XDPA 1CR5A 4KO8A 3CF2A 1QCNA 4AS1A 2PWYA 5D6XA 3LGAA 3LHDA 5GLFA 4ARIA 1QCSA 4KDIA 2EB5A 2JV2A 2Q1AX 3BQBA 2Q1CX 3LZKA 5D2IA 2Q1DX 3QQ8A 3S52A 4DBFA 1QDNA 2Q18X 2QQRA 1QCOA 2QQSA 5CCXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WQT A;  3R6O A;  1HYO A;  1WZO A;  1QQJ A;  5D2K A;  4MAQ A;  1QCN A;  2HZY A;  4DBH A;  3RR6 A;  4QKU A;  1I7O A;  1NKQ A;  2Q19 X;  2EB6 A;  1SAW A;  3QDF A;  3V77 A;  5D2H A;  2EB5 A;  2Q1A X;  3BQB A;  5D2J A;  2Q1C X;  3LZK A;  2DFU A;  5D2I A;  2Q1D X;  1QCO A;  5D2F A;  5D2G A;  3S52 A;  4DBF A;  2Q18 X;  1NR9 A;  1GTT A;  1SV6 A;  4PFZ A;  2EB4 A; 
#chains in the Genus database with same CATH topology
 3QC8 A;  1WZO A;  3QQ7 A;  2YVL A;  2HZY A;  5B6C A;  3HU3 A;  3FPU A;  2Q19 X;  5FTM A;  2MM2 A;  3V77 A;  5EQJ B;  5D2H A;  5CD1 A;  3HU1 A;  5D2J A;  5DYG A;  3FPR A;  3ZGZ A;  4ARC A;  1WLF A;  4KLN A;  2B25 A;  3R6O A;  1CZ5 A;  1QQJ A;  1CZ4 A;  1R7R A;  4MAQ A;  4DBH A;  5CCB A;  2PJH B;  1NKQ A;  4CQN A;  5FTL A;  1SAW A;  2LW6 A;  2GFA A;  3QDF A;  5FTJ A;  4RV0 A;  5C18 A;  5C1B A;  5D6Y A;  5D2G A;  3MB5 A;  3ZJT A;  5ERG B;  1I9G A;  1I7O A;  2WQT A;  2EB4 A;  1ZC1 A;  2GF7 A;  5D2K A;  5DYI A;  4KDL A;  3ZJV A;  3RR6 A;  4QKU A;  3QWZ A;  3ZJU A;  4FIB A;  5FTN A;  4AQ7 A;  2EB6 A;  3FPT A;  4KOD A;  1E32 A;  2KY9 A;  3TIW A;  1S3S A;  5D6W A;  2DFU A;  2MM0 A;  5FTK A;  1O54 A;  1NR9 A;  1GTT A;  4UC4 A;  1SV6 A;  4PFZ A;  5D2F A;  2YUJ A;  3HU2 A;  1HYO A;  5EPP A;  2XDP A;  1CR5 A;  4KO8 A;  3CF2 A;  1QCN A;  4AS1 A;  2PWY A;  5D6X A;  3LGA A;  3LHD A;  5GLF A;  4ARI A;  1QCS A;  4KDI A;  2EB5 A;  2JV2 A;  2Q1A X;  3BQB A;  2Q1C X;  3LZK A;  5D2I A;  2Q1D X;  3QQ8 A;  3S52 A;  4DBF A;  1QDN A;  2Q18 X;  2QQR A;  1QCO A;  2QQS A;  5CCX A; 
#chains in the Genus database with same CATH homology
 3QC8 A;  1WZO A;  3QQ7 A;  2YVL A;  2HZY A;  5B6C A;  3HU3 A;  3FPU A;  2Q19 X;  5FTM A;  2MM2 A;  3V77 A;  5EQJ B;  5D2H A;  5CD1 A;  3HU1 A;  5D2J A;  5DYG A;  3FPR A;  3ZGZ A;  4ARC A;  1WLF A;  4KLN A;  2B25 A;  3R6O A;  1CZ5 A;  1QQJ A;  1CZ4 A;  1R7R A;  4MAQ A;  4DBH A;  5CCB A;  2PJH B;  1NKQ A;  4CQN A;  5FTL A;  1SAW A;  2LW6 A;  2GFA A;  3QDF A;  5FTJ A;  4RV0 A;  5C18 A;  5C1B A;  5D6Y A;  5D2G A;  3MB5 A;  3ZJT A;  5ERG B;  1I9G A;  1I7O A;  2WQT A;  2EB4 A;  1ZC1 A;  2GF7 A;  5D2K A;  5DYI A;  4KDL A;  3ZJV A;  3RR6 A;  4QKU A;  3QWZ A;  3ZJU A;  4FIB A;  5FTN A;  4AQ7 A;  2EB6 A;  3FPT A;  4KOD A;  1E32 A;  2KY9 A;  3TIW A;  1S3S A;  5D6W A;  2DFU A;  2MM0 A;  5FTK A;  1O54 A;  1NR9 A;  1GTT A;  4UC4 A;  1SV6 A;  4PFZ A;  5D2F A;  2YUJ A;  3HU2 A;  1HYO A;  5EPP A;  2XDP A;  1CR5 A;  4KO8 A;  3CF2 A;  1QCN A;  4AS1 A;  2PWY A;  5D6X A;  3LGA A;  3LHD A;  5GLF A;  4ARI A;  1QCS A;  4KDI A;  2EB5 A;  2JV2 A;  2Q1A X;  3BQB A;  2Q1C X;  3LZK A;  5D2I A;  2Q1D X;  3QQ8 A;  3S52 A;  4DBF A;  1QDN A;  2Q18 X;  2QQR A;  1QCO A;  2QQS A;  5CCX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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