2Q1CX

2-keto-3-deoxy-d-arabinonate dehydratase complexed with calcium and 2-oxobutyrate
Total Genus 74
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
291
structure length
291
Chain Sequence
MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily.
pubmed doi rcsb
molecule tags Lyase
source organism Sulfolobus solfataricus
molecule keywords 2-keto-3-deoxy-D-arabinonate dehydratase
total genus 74
structure length 291
sequence length 291
ec nomenclature ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date 2007-05-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
X PF01557 FAA_hydrolase Fumarylacetoacetate (FAA) hydrolase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.330.40 Alpha Beta Roll Vcp-like ATPase; Chain A, domain 2 Vcp-like ATPase; Chain A, domain 2 2q1cX01
3.90.850.10 Alpha Beta Alpha-Beta Complex Fumarylacetoacetate hydrolase; domain 2 Fumarylacetoacetase-like, C-terminal domain 2q1cX02
5D2HA 4QKUA 4DBHA 1NR9A 2Q1CX 3V77A 2DFUA 1HYOA 4MAQA 5D2FA 2Q1DX 5D2KA 3R6OA 4PFZA 3QDFA 4DBFA 5D2GA 2Q18X 1QCNA 1WZOA 2HZYA 2WQTA 1NKQA 1SAWA 1GTTA 1I7OA 2EB5A 2Q19X 3LZKA 3RR6A 2Q1AX 2EB6A 1SV6A 2EB4A 1QCOA 5D2IA 5D2JA 1QQJA 3BQBA 3S52A
chains in the Genus database with same CATH superfamily
5D2HA 1QDNA 3ZJVA 3V77A 1E32A 1HYOA 5EQJB 3ZJTA 2MM0A 5FTKA 5GLFA 5D2KA 5ERGB 3FPUA 5D6WA 4DBFA 2WQTA 2PJHB 2QQSA 4KODA 1CZ5A 4FIBA 1WLFA 2B25A 3QWZA 3ZGZA 5EPPA 1QCSA 4KLNA 2GF7A 2Q1AX 5CCXA 3MB5A 5CCBA 2YUJA 2Q1CX 1ZC1A 3LHDA 1R7RA 1S3SA 5FTJA 4MAQA 2GFAA 3LGAA 2Q1DX 5B6CA 5FTLA 4KDLA 5C1BA 2MM2A 2HZYA 1WZOA 2EB5A 2Q19X 3LZKA 5CD1A 2EB4A 1QCOA 1QQJA 5D6YA 3BQBA 4KO8A 4RV0A 4UC4A 1CZ4A 3FPRA 4QKUA 4DBHA 4ARIA 2QQRA 4AQ7A 3HU2A 5D2FA 3QC8A 3R6OA 4PFZA 2Q18X 1QCNA 5D6XA 1NKQA 3FPTA 1SAWA 1I7OA 5FTMA 4CQNA 3HU3A 4KDIA 3QQ8A 2EB6A 5D2IA 3CF2A 1O54A 3TIWA 1NR9A 2LW6A 1I9GA 2DFUA 5DYIA 5DYGA 2YVLA 2JV2A 2KY9A 5FTNA 3QDFA 5D2GA 2PWYA 1GTTA 3ZJUA 4AS1A 3HU1A 3RR6A 1SV6A 3QQ7A 4ARCA 5C18A 5D2JA 2XDPA 3S52A 1CR5A
chains in the Genus database with same CATH topology
5D2HA 1QDNA 3ZJVA 3V77A 1E32A 1HYOA 5EQJB 3ZJTA 2MM0A 5FTKA 5GLFA 5D2KA 5ERGB 3FPUA 5D6WA 4DBFA 2WQTA 2PJHB 2QQSA 4KODA 1CZ5A 4FIBA 1WLFA 2B25A 3QWZA 3ZGZA 5EPPA 1QCSA 4KLNA 2GF7A 2Q1AX 5CCXA 3MB5A 5CCBA 2YUJA 2Q1CX 1ZC1A 3LHDA 1R7RA 1S3SA 5FTJA 4MAQA 2GFAA 3LGAA 2Q1DX 5B6CA 5FTLA 4KDLA 5C1BA 2MM2A 2HZYA 1WZOA 2EB5A 2Q19X 3LZKA 5CD1A 2EB4A 1QCOA 1QQJA 5D6YA 3BQBA 4KO8A 4RV0A 4UC4A 1CZ4A 3FPRA 4QKUA 4DBHA 4ARIA 2QQRA 4AQ7A 3HU2A 5D2FA 3QC8A 3R6OA 4PFZA 2Q18X 1QCNA 5D6XA 1NKQA 3FPTA 1SAWA 1I7OA 5FTMA 4CQNA 3HU3A 4KDIA 3QQ8A 2EB6A 5D2IA 3CF2A 1O54A 3TIWA 1NR9A 2LW6A 1I9GA 2DFUA 5DYIA 5DYGA 2YVLA 2JV2A 2KY9A 5FTNA 3QDFA 5D2GA 2PWYA 1GTTA 3ZJUA 4AS1A 3HU1A 3RR6A 1SV6A 3QQ7A 4ARCA 5C18A 5D2JA 2XDPA 3S52A 1CR5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D2H A;  4QKU A;  4DBH A;  1NR9 A;  2Q1C X;  3V77 A;  2DFU A;  1HYO A;  4MAQ A;  5D2F A;  2Q1D X;  5D2K A;  3R6O A;  4PFZ A;  3QDF A;  4DBF A;  5D2G A;  2Q18 X;  1QCN A;  1WZO A;  2HZY A;  2WQT A;  1NKQ A;  1SAW A;  1GTT A;  1I7O A;  2EB5 A;  2Q19 X;  3LZK A;  3RR6 A;  2Q1A X;  2EB6 A;  1SV6 A;  2EB4 A;  1QCO A;  5D2I A;  5D2J A;  1QQJ A;  3BQB A;  3S52 A; 
#chains in the Genus database with same CATH topology
 5D2H A;  1QDN A;  3ZJV A;  3V77 A;  1E32 A;  1HYO A;  5EQJ B;  3ZJT A;  2MM0 A;  5FTK A;  5GLF A;  5D2K A;  5ERG B;  3FPU A;  5D6W A;  4DBF A;  2WQT A;  2PJH B;  2QQS A;  4KOD A;  1CZ5 A;  4FIB A;  1WLF A;  2B25 A;  3QWZ A;  3ZGZ A;  5EPP A;  1QCS A;  4KLN A;  2GF7 A;  2Q1A X;  5CCX A;  3MB5 A;  5CCB A;  2YUJ A;  2Q1C X;  1ZC1 A;  3LHD A;  1R7R A;  1S3S A;  5FTJ A;  4MAQ A;  2GFA A;  3LGA A;  2Q1D X;  5B6C A;  5FTL A;  4KDL A;  5C1B A;  2MM2 A;  2HZY A;  1WZO A;  2EB5 A;  2Q19 X;  3LZK A;  5CD1 A;  2EB4 A;  1QCO A;  1QQJ A;  5D6Y A;  3BQB A;  4KO8 A;  4RV0 A;  4UC4 A;  1CZ4 A;  3FPR A;  4QKU A;  4DBH A;  4ARI A;  2QQR A;  4AQ7 A;  3HU2 A;  5D2F A;  3QC8 A;  3R6O A;  4PFZ A;  2Q18 X;  1QCN A;  5D6X A;  1NKQ A;  3FPT A;  1SAW A;  1I7O A;  5FTM A;  4CQN A;  3HU3 A;  4KDI A;  3QQ8 A;  2EB6 A;  5D2I A;  3CF2 A;  1O54 A;  3TIW A;  1NR9 A;  2LW6 A;  1I9G A;  2DFU A;  5DYI A;  5DYG A;  2YVL A;  2JV2 A;  2KY9 A;  5FTN A;  3QDF A;  5D2G A;  2PWY A;  1GTT A;  3ZJU A;  4AS1 A;  3HU1 A;  3RR6 A;  1SV6 A;  3QQ7 A;  4ARC A;  5C18 A;  5D2J A;  2XDP A;  3S52 A;  1CR5 A; 
#chains in the Genus database with same CATH homology
 5D2H A;  1QDN A;  3ZJV A;  3V77 A;  1E32 A;  1HYO A;  5EQJ B;  3ZJT A;  2MM0 A;  5FTK A;  5GLF A;  5D2K A;  5ERG B;  3FPU A;  5D6W A;  4DBF A;  2WQT A;  2PJH B;  2QQS A;  4KOD A;  1CZ5 A;  4FIB A;  1WLF A;  2B25 A;  3QWZ A;  3ZGZ A;  5EPP A;  1QCS A;  4KLN A;  2GF7 A;  2Q1A X;  5CCX A;  3MB5 A;  5CCB A;  2YUJ A;  2Q1C X;  1ZC1 A;  3LHD A;  1R7R A;  1S3S A;  5FTJ A;  4MAQ A;  2GFA A;  3LGA A;  2Q1D X;  5B6C A;  5FTL A;  4KDL A;  5C1B A;  2MM2 A;  2HZY A;  1WZO A;  2EB5 A;  2Q19 X;  3LZK A;  5CD1 A;  2EB4 A;  1QCO A;  1QQJ A;  5D6Y A;  3BQB A;  4KO8 A;  4RV0 A;  4UC4 A;  1CZ4 A;  3FPR A;  4QKU A;  4DBH A;  4ARI A;  2QQR A;  4AQ7 A;  3HU2 A;  5D2F A;  3QC8 A;  3R6O A;  4PFZ A;  2Q18 X;  1QCN A;  5D6X A;  1NKQ A;  3FPT A;  1SAW A;  1I7O A;  5FTM A;  4CQN A;  3HU3 A;  4KDI A;  3QQ8 A;  2EB6 A;  5D2I A;  3CF2 A;  1O54 A;  3TIW A;  1NR9 A;  2LW6 A;  1I9G A;  2DFU A;  5DYI A;  5DYG A;  2YVL A;  2JV2 A;  2KY9 A;  5FTN A;  3QDF A;  5D2G A;  2PWY A;  1GTT A;  3ZJU A;  4AS1 A;  3HU1 A;  3RR6 A;  1SV6 A;  3QQ7 A;  4ARC A;  5C18 A;  5D2J A;  2XDP A;  3S52 A;  1CR5 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...