2Q1C | Genus

Total Genus 74

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	74
sequence length	291
structure length	291
Chain Sequence	MKLFRVVKRGYYISYAILDNSTIIRLDEDPIKALMRYSENKEVLGDRVTGIDYQSLLKSFQINDIRITKPIDPPEVWGSGISYEMARERYSEENVAKILGKTIYEKVYDAVRPEIFFKATPNRCVGHGEAIAVRSDSEWTLPEPELAVVLDSNGKILGYTIMDDVSARDLEAENPLYLPQSKIYAGCCAFGPVIVTSDEIKNPYSLDITLKIVREGRVFFEGSVNTNKMRRKIEEQIQYLIRDNPIPDGTILTTGTAIVPGRDKGLKDEDIVEITISNIGTLITPVKKRRK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase
source organism	Sulfolobus solfataricus
publication title	Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily. pubmed doi rcsb
molecule keywords	2-keto-3-deoxy-D-arabinonate dehydratase
total genus	74
structure length	291
sequence length	291
ec nomenclature	ec 4.2.1.141: 2-dehydro-3-deoxy-D-arabinonate dehydratase.
pdb deposition date	2007-05-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
X	PF01557	FAA_hydrolase	Fumarylacetoacetate (FAA) hydrolase family

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.10.330.40	Alpha Beta	Roll	Vcp-like ATPase; Chain A, domain 2	Vcp-like ATPase; Chain A, domain 2	2q1cX01
3.90.850.10	Alpha Beta	Alpha-Beta Complex	Fumarylacetoacetate hydrolase; domain 2	Fumarylacetoacetase-like, C-terminal domain	2q1cX02

5D2KA 5D2FA 1HYOA 3LZKA 2Q1DX 2DFUA 4MAQA 3RR6A 4DBFA 4DBHA 1NR9A 2EB6A 2EB4A 3QDFA 5D2IA 2WQTA 4QKUA 3V77A 3R6OA 1GTTA 5D2HA 1QQJA 5D2JA 1WZOA 1QCNA 1I7OA 4PFZA 2Q18X 3BQBA 1QCOA 5D2GA 2Q1CX 1NKQA 2HZYA 2Q1AX 1SV6A 2Q19X 1SAWA 2EB5A 3S52A
chains in the Genus database with same CATH superfamily

3FPTA 4KODA 2QQSA 2Q1DX 2PWYA 1NR9A 3QDFA 4ARCA 4ARIA 5C18A 4QKUA 5D6YA 4KDIA 1QCNA 2GF7A 2MM0A 4PFZA 3QWZA 5FTJA 2PJHB 3HU2A 4AQ7A 1QCOA 3TIWA 4RV0A 4KO8A 2HZYA 5CCXA 1CR5A 2EB5A 1S3SA 3HU1A 5CD1A 2DFUA 2GFAA 4MAQA 4AS1A 4DBFA 5FTMA 2EB6A 5DYIA 4UC4A 2KY9A 3V77A 1QCSA 3QC8A 1QDNA 5D2HA 1WZOA 2Q18X 2XDPA 5D2GA 1R7RA 2Q1CX 4FIBA 5DYGA 3MB5A 1SAWA 4KLNA 3ZGZA 5ERGB 3HU3A 1ZC1A 3LZKA 5CCBA 3RR6A 4DBHA 1WLFA 2EB4A 5D2IA 3CF2A 2WQTA 5FTNA 3LGAA 5D6XA 3R6OA 5EQJB 5D6WA 1GTTA 5B6CA 5FTLA 1I7OA 2YUJA 3ZJVA 1CZ5A 1NKQA 2MM2A 3LHDA 4CQNA 1SV6A 2Q19X 2QQRA 3QQ7A 4KDLA 1I9GA 2LW6A 3S52A 5D2KA 5D2FA 1HYOA 1QQJA 1O54A 5GLFA 5D2JA 2JV2A 1E32A 3FPRA 3FPUA 5EPPA 3BQBA 5FTKA 2YVLA 3ZJTA 3ZJUA 2B25A 5C1BA 2Q1AX 1CZ4A 3QQ8A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5D2K A;  5D2F A;  1HYO A;  3LZK A;  2Q1D X;  2DFU A;  4MAQ A;  3RR6 A;  4DBF A;  4DBH A;  1NR9 A;  2EB6 A;  2EB4 A;  3QDF A;  5D2I A;  2WQT A;  4QKU A;  3V77 A;  3R6O A;  1GTT A;  5D2H A;  1QQJ A;  5D2J A;  1WZO A;  1QCN A;  1I7O A;  4PFZ A;  2Q18 X;  3BQB A;  1QCO A;  5D2G A;  2Q1C X;  1NKQ A;  2HZY A;  2Q1A X;  1SV6 A;  2Q19 X;  1SAW A;  2EB5 A;  3S52 A; 
#chains in the Genus database with same CATH topology
 3FPT A;  4KOD A;  2QQS A;  2Q1D X;  2PWY A;  1NR9 A;  3QDF A;  4ARC A;  4ARI A;  5C18 A;  4QKU A;  5D6Y A;  4KDI A;  1QCN A;  2GF7 A;  2MM0 A;  4PFZ A;  3QWZ A;  5FTJ A;  2PJH B;  3HU2 A;  4AQ7 A;  1QCO A;  3TIW A;  4RV0 A;  4KO8 A;  2HZY A;  5CCX A;  1CR5 A;  2EB5 A;  1S3S A;  3HU1 A;  5CD1 A;  2DFU A;  2GFA A;  4MAQ A;  4AS1 A;  4DBF A;  5FTM A;  2EB6 A;  5DYI A;  4UC4 A;  2KY9 A;  3V77 A;  1QCS A;  3QC8 A;  1QDN A;  5D2H A;  1WZO A;  2Q18 X;  2XDP A;  5D2G A;  1R7R A;  2Q1C X;  4FIB A;  5DYG A;  3MB5 A;  1SAW A;  4KLN A;  3ZGZ A;  5ERG B;  3HU3 A;  1ZC1 A;  3LZK A;  5CCB A;  3RR6 A;  4DBH A;  1WLF A;  2EB4 A;  5D2I A;  3CF2 A;  2WQT A;  5FTN A;  3LGA A;  5D6X A;  3R6O A;  5EQJ B;  5D6W A;  1GTT A;  5B6C A;  5FTL A;  1I7O A;  2YUJ A;  3ZJV A;  1CZ5 A;  1NKQ A;  2MM2 A;  3LHD A;  4CQN A;  1SV6 A;  2Q19 X;  2QQR A;  3QQ7 A;  4KDL A;  1I9G A;  2LW6 A;  3S52 A;  5D2K A;  5D2F A;  1HYO A;  1QQJ A;  1O54 A;  5GLF A;  5D2J A;  2JV2 A;  1E32 A;  3FPR A;  3FPU A;  5EPP A;  3BQB A;  5FTK A;  2YVL A;  3ZJT A;  3ZJU A;  2B25 A;  5C1B A;  2Q1A X;  1CZ4 A;  3QQ8 A; 
#chains in the Genus database with same CATH homology
 3FPT A;  4KOD A;  2QQS A;  2Q1D X;  2PWY A;  1NR9 A;  3QDF A;  4ARC A;  4ARI A;  5C18 A;  4QKU A;  5D6Y A;  4KDI A;  1QCN A;  2GF7 A;  2MM0 A;  4PFZ A;  3QWZ A;  5FTJ A;  2PJH B;  3HU2 A;  4AQ7 A;  1QCO A;  3TIW A;  4RV0 A;  4KO8 A;  2HZY A;  5CCX A;  1CR5 A;  2EB5 A;  1S3S A;  3HU1 A;  5CD1 A;  2DFU A;  2GFA A;  4MAQ A;  4AS1 A;  4DBF A;  5FTM A;  2EB6 A;  5DYI A;  4UC4 A;  2KY9 A;  3V77 A;  1QCS A;  3QC8 A;  1QDN A;  5D2H A;  1WZO A;  2Q18 X;  2XDP A;  5D2G A;  1R7R A;  2Q1C X;  4FIB A;  5DYG A;  3MB5 A;  1SAW A;  4KLN A;  3ZGZ A;  5ERG B;  3HU3 A;  1ZC1 A;  3LZK A;  5CCB A;  3RR6 A;  4DBH A;  1WLF A;  2EB4 A;  5D2I A;  3CF2 A;  2WQT A;  5FTN A;  3LGA A;  5D6X A;  3R6O A;  5EQJ B;  5D6W A;  1GTT A;  5B6C A;  5FTL A;  1I7O A;  2YUJ A;  3ZJV A;  1CZ5 A;  1NKQ A;  2MM2 A;  3LHD A;  4CQN A;  1SV6 A;  2Q19 X;  2QQR A;  3QQ7 A;  4KDL A;  1I9G A;  2LW6 A;  3S52 A;  5D2K A;  5D2F A;  1HYO A;  1QQJ A;  1O54 A;  5GLF A;  5D2J A;  2JV2 A;  1E32 A;  3FPR A;  3FPU A;  5EPP A;  3BQB A;  5FTK A;  2YVL A;  3ZJT A;  3ZJU A;  2B25 A;  5C1B A;  2Q1A X;  1CZ4 A;  3QQ8 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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2Q1CX

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations