2RFKA

Substrate rna positioning in the archaeal h/aca ribonucleoprotein complex
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
334
structure length
334
Chain Sequence
EVRRILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLAPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLWEKRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex.
pubmed doi rcsb
molecule tags Isomerase/rna
source organism Pyrococcus furiosus
molecule keywords guide RNA 1
total genus 73
structure length 334
sequence length 334
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2007-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 2rfkA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 2rfkA02
3ZV0C 3HJYA 3DH3A 3HAXA 3LWPA 3LWVA 3LWOA 2HVYA 1V9KA 1KSLA 1SGVA 1QYUA 4LGTA 2AUSA 4LABA 1XPIA 1ZE1A 1V9FA 3MQKA 2APOA 1ZE2A 1KSVA 1R3FA 3HJWA 1PRZA 1KSKA 2ISTA 1ZL3A 1R3EA 2I82A 3U28A 2EY4A 3LWQA 3UAIA 2AB4A 2RFKA 1K8WA 3LWRA
chains in the Genus database with same CATH superfamily
3M6VA 4DMGA 4CI1B 3HJYA 4CI3B 3DH3A 3HAXA 3LWVA 2HVYA 1WXXA 1V9KA 2CX1A 2AUSA 1V9FA 1PRZA 2ISTA 1ZL3A 2I82A 3M6XA 3LWQA 2AB4A 2DP9A 3LWRA 1TE7A 1IQ8A 4CI2B 1WXWA 3LWPA 3IUWA 2E5OA 2ANEA 1SGVA 1QYUA 4LGTA 1IT7A 2FRXA 3MQKA 1ZE2A 2Z0TA 3M6UA 3VSEA 2CWWA 2P38A 1R3EA 4Q1TA 3D79A 2EY4A 3UAIA 2KKUA 1K8WA 1ZS7A 3M6WA 3C0KA 1SQWA 2J5VA 1XPIA 3LJCA 1ZE1A 1SZWA 1Z2ZA 2APOA 1S04A 2Q07A 1SI7A 1R3FA 1KSKA 1T5YA 2AS0A 2CX0A 2RFKA 2J5TA 1SB7A 3ZV0C 3M4XA 1UOYA 1J2BA 3M65A 1XNEA 3LWOA 4TZ4C 1KSLA 1WK2A 2B78A 1IT8A 4LABA 3LDFA 1KSVA 3HJWA 1ZBOA 3U28A 1Q7HA
chains in the Genus database with same CATH topology
3M6VA 3ZV0C 3M6WA 3HJYA 3M4XA 3HAXA 3DH3A 3LWPA 1UOYA 3LWVA 3LWOA 2HVYA 1V9KA 1KSLA 1SGVA 1QYUA 4LGTA 2AUSA 4LABA 1XPIA 1SZWA 1ZE1A 2FRXA 1V9FA 3MQKA 1Z2ZA 2APOA 1ZE2A 3M6UA 1KSVA 1SI7A 1R3FA 3HJWA 1PRZA 1SB7A 1KSKA 2ISTA 1ZL3A 1R3EA 2I82A 3U28A 3M6XA 2EY4A 3LWQA 3UAIA 2AB4A 2RFKA 1K8WA 3LWRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZV0 C;  3HJY A;  3DH3 A;  3HAX A;  3LWP A;  3LWV A;  3LWO A;  2HVY A;  1V9K A;  1KSL A;  1SGV A;  1QYU A;  4LGT A;  2AUS A;  4LAB A;  1XPI A;  1ZE1 A;  1V9F A;  3MQK A;  2APO A;  1ZE2 A;  1KSV A;  1R3F A;  3HJW A;  1PRZ A;  1KSK A;  2IST A;  1ZL3 A;  1R3E A;  2I82 A;  3U28 A;  2EY4 A;  3LWQ A;  3UAI A;  2AB4 A;  2RFK A;  1K8W A;  3LWR A; 
#chains in the Genus database with same CATH topology
 3M6V A;  4DMG A;  4CI1 B;  3HJY A;  4CI3 B;  3DH3 A;  3HAX A;  3LWV A;  2HVY A;  1WXX A;  1V9K A;  2CX1 A;  2AUS A;  1V9F A;  1PRZ A;  2IST A;  1ZL3 A;  2I82 A;  3M6X A;  3LWQ A;  2AB4 A;  2DP9 A;  3LWR A;  1TE7 A;  1IQ8 A;  4CI2 B;  1WXW A;  3LWP A;  3IUW A;  2E5O A;  2ANE A;  1SGV A;  1QYU A;  4LGT A;  1IT7 A;  2FRX A;  3MQK A;  1ZE2 A;  2Z0T A;  3M6U A;  3VSE A;  2CWW A;  2P38 A;  1R3E A;  4Q1T A;  3D79 A;  2EY4 A;  3UAI A;  2KKU A;  1K8W A;  1ZS7 A;  3M6W A;  3C0K A;  1SQW A;  2J5V A;  1XPI A;  3LJC A;  1ZE1 A;  1SZW A;  1Z2Z A;  2APO A;  1S04 A;  2Q07 A;  1SI7 A;  1R3F A;  1KSK A;  1T5Y A;  2AS0 A;  2CX0 A;  2RFK A;  2J5T A;  1SB7 A;  3ZV0 C;  3M4X A;  1UOY A;  1J2B A;  3M65 A;  1XNE A;  3LWO A;  4TZ4 C;  1KSL A;  1WK2 A;  2B78 A;  1IT8 A;  4LAB A;  3LDF A;  1KSV A;  3HJW A;  1ZBO A;  3U28 A;  1Q7H A; 
#chains in the Genus database with same CATH homology
 3M6V A;  3ZV0 C;  3M6W A;  3HJY A;  3M4X A;  3HAX A;  3DH3 A;  3LWP A;  1UOY A;  3LWV A;  3LWO A;  2HVY A;  1V9K A;  1KSL A;  1SGV A;  1QYU A;  4LGT A;  2AUS A;  4LAB A;  1XPI A;  1SZW A;  1ZE1 A;  2FRX A;  1V9F A;  3MQK A;  1Z2Z A;  2APO A;  1ZE2 A;  3M6U A;  1KSV A;  1SI7 A;  1R3F A;  3HJW A;  1PRZ A;  1SB7 A;  1KSK A;  2IST A;  1ZL3 A;  1R3E A;  2I82 A;  3U28 A;  3M6X A;  2EY4 A;  3LWQ A;  3UAI A;  2AB4 A;  2RFK A;  1K8W A;  3LWR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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