3HJWA

Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate rna
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
327
structure length
327
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
pubmed doi rcsb
molecule tags Isomerase/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 96
structure length 327
sequence length 327
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2009-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 3hjwA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3hjwA02
1KSLA 1V9FA 1ZE1A 2APOA 3DH3A 2EY4A 1SGVA 3LWVA 1QYUA 1V9KA 1ZE2A 3LWOA 2AUSA 3MQKA 2RFKA 1PRZA 3LWQA 1K8WA 4LGTA 2AB4A 1R3FA 2ISTA 3UAIA 2HVYA 1XPIA 4LABA 1ZL3A 1KSVA 3LWRA 1KSKA 3HJYA 3LWPA 3HJWA 2I82A 3U28A 3HAXA 1R3EA 3ZV0C
chains in the Genus database with same CATH superfamily
1SI7A 2Q07A 2AS0A 1Q7HA 3LWVA 3M6VA 3IUWA 1IQ8A 1QYUA 3LWOA 2KKUA 4DMGA 1ZS7A 3MQKA 2RFKA 3LWQA 3VSEA 4CI2B 3M6XA 2ISTA 3UAIA 1XPIA 2J5VA 1WXXA 1SB7A 3HAXA 1V9FA 1ZE1A 2APOA 3DH3A 2EY4A 4Q1TA 1V9KA 2ANEA 1ZE2A 2E5OA 1IT7A 2Z0TA 1WXWA 1T5YA 1KSVA 3LJCA 1S04A 1KSKA 1IT8A 1J2BA 1ZBOA 2I82A 2CWWA 3U28A 1R3EA 1KSLA 3M65A 4CI3B 1UOYA 3M6WA 1SGVA 2P38A 3D79A 1TE7A 3C0KA 2AUSA 1PRZA 3M6UA 2FRXA 2CX0A 2DP9A 3LDFA 1WK2A 2HVYA 4LABA 2B78A 3LWPA 3HJWA 1XNEA 2J5TA 1SQWA 4TZ4C 1K8WA 2AB4A 4LGTA 1R3FA 3M4XA 1SZWA 4CI1B 1ZL3A 3LWRA 1Z2ZA 2CX1A 3HJYA 3ZV0C
chains in the Genus database with same CATH topology
1KSLA 1SI7A 1V9FA 1ZE1A 2APOA 3DH3A 1UOYA 2EY4A 3M6WA 1SGVA 3LWVA 3M6VA 1QYUA 1V9KA 1ZE2A 3LWOA 2AUSA 3MQKA 2RFKA 3M6UA 3LWQA 1PRZA 1K8WA 2FRXA 4LGTA 2AB4A 1R3FA 3M4XA 3M6XA 1SZWA 2ISTA 3UAIA 2HVYA 1XPIA 4LABA 1ZL3A 1KSVA 3LWRA 1Z2ZA 1KSKA 3HJYA 3LWPA 3HJWA 2I82A 1SB7A 3U28A 3HAXA 1R3EA 3ZV0C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSL A;  1V9F A;  1ZE1 A;  2APO A;  3DH3 A;  2EY4 A;  1SGV A;  3LWV A;  1QYU A;  1V9K A;  1ZE2 A;  3LWO A;  2AUS A;  3MQK A;  2RFK A;  1PRZ A;  3LWQ A;  1K8W A;  4LGT A;  2AB4 A;  1R3F A;  2IST A;  3UAI A;  2HVY A;  1XPI A;  4LAB A;  1ZL3 A;  1KSV A;  3LWR A;  1KSK A;  3HJY A;  3LWP A;  3HJW A;  2I82 A;  3U28 A;  3HAX A;  1R3E A;  3ZV0 C; 
#chains in the Genus database with same CATH topology
 1SI7 A;  2Q07 A;  2AS0 A;  1Q7H A;  3LWV A;  3M6V A;  3IUW A;  1IQ8 A;  1QYU A;  3LWO A;  2KKU A;  4DMG A;  1ZS7 A;  3MQK A;  2RFK A;  3LWQ A;  3VSE A;  4CI2 B;  3M6X A;  2IST A;  3UAI A;  1XPI A;  2J5V A;  1WXX A;  1SB7 A;  3HAX A;  1V9F A;  1ZE1 A;  2APO A;  3DH3 A;  2EY4 A;  4Q1T A;  1V9K A;  2ANE A;  1ZE2 A;  2E5O A;  1IT7 A;  2Z0T A;  1WXW A;  1T5Y A;  1KSV A;  3LJC A;  1S04 A;  1KSK A;  1IT8 A;  1J2B A;  1ZBO A;  2I82 A;  2CWW A;  3U28 A;  1R3E A;  1KSL A;  3M65 A;  4CI3 B;  1UOY A;  3M6W A;  1SGV A;  2P38 A;  3D79 A;  1TE7 A;  3C0K A;  2AUS A;  1PRZ A;  3M6U A;  2FRX A;  2CX0 A;  2DP9 A;  3LDF A;  1WK2 A;  2HVY A;  4LAB A;  2B78 A;  3LWP A;  3HJW A;  1XNE A;  2J5T A;  1SQW A;  4TZ4 C;  1K8W A;  2AB4 A;  4LGT A;  1R3F A;  3M4X A;  1SZW A;  4CI1 B;  1ZL3 A;  3LWR A;  1Z2Z A;  2CX1 A;  3HJY A;  3ZV0 C; 
#chains in the Genus database with same CATH homology
 1KSL A;  1SI7 A;  1V9F A;  1ZE1 A;  2APO A;  3DH3 A;  1UOY A;  2EY4 A;  3M6W A;  1SGV A;  3LWV A;  3M6V A;  1QYU A;  1V9K A;  1ZE2 A;  3LWO A;  2AUS A;  3MQK A;  2RFK A;  3M6U A;  3LWQ A;  1PRZ A;  1K8W A;  2FRX A;  4LGT A;  2AB4 A;  1R3F A;  3M4X A;  3M6X A;  1SZW A;  2IST A;  3UAI A;  2HVY A;  1XPI A;  4LAB A;  1ZL3 A;  1KSV A;  3LWR A;  1Z2Z A;  1KSK A;  3HJY A;  3LWP A;  3HJW A;  2I82 A;  1SB7 A;  3U28 A;  3HAX A;  1R3E A;  3ZV0 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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