3HJWA

Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate rna
Total Genus 96
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
96
sequence length
327
structure length
327
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
pubmed doi rcsb
molecule tags Isomerase/rna
source organism Pyrococcus furiosus
molecule keywords Pseudouridine synthase Cbf5
total genus 96
structure length 327
sequence length 327
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2009-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 3hjwA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3hjwA02
1QYUA 1V9FA 3DH3A 3HJWA 2AB4A 1R3EA 1KSLA 3MQKA 3LWRA 2APOA 1K8WA 1KSVA 3LWVA 1R3FA 3HAXA 1SGVA 2ISTA 4LABA 2RFKA 1KSKA 2I82A 3LWOA 2HVYA 2EY4A 1ZL3A 3HJYA 1PRZA 1V9KA 3LWQA 3LWPA 3U28A 1XPIA 1ZE2A 3UAIA 4LGTA 1ZE1A 3ZV0C 2AUSA
chains in the Genus database with same CATH superfamily
1QYUA 2B78A 1V9FA 1T5YA 1R3EA 2CX0A 3MQKA 1SQWA 3IUWA 2E5OA 4TZ4C 1KSVA 1XNEA 4CI3B 3HAXA 2ISTA 2RFKA 2DP9A 2ANEA 3HJYA 3LWPA 1ZBOA 3M65A 1Q7HA 3D79A 3M6XA 1SB7A 2Z0TA 2P38A 3VSEA 2APOA 1K8WA 3LWVA 4LABA 1WXWA 1Z2ZA 3LJCA 3M6WA 4LGTA 1TE7A 1ZS7A 4CI1B 1WXXA 4DMGA 3DH3A 3HJWA 2AB4A 1UOYA 1SI7A 1KSLA 3M6VA 3LWRA 4CI2B 1R3FA 2J5TA 1IT8A 1S04A 1KSKA 3C0KA 1V9KA 3U28A 1XPIA 3M4XA 2Q07A 1SZWA 2J5VA 3LDFA 2CWWA 4Q1TA 2CX1A 1J2BA 2FRXA 1SGVA 2I82A 1WK2A 2KKUA 3LWOA 1ZL3A 2EY4A 2HVYA 1IQ8A 1PRZA 3LWQA 1IT7A 1ZE2A 3M6UA 3UAIA 1ZE1A 3ZV0C 2AS0A 2AUSA
chains in the Genus database with same CATH topology
1QYUA 3M6XA 1SB7A 1V9FA 3M4XA 1SZWA 3DH3A 3HJWA 2AB4A 1R3EA 1UOYA 1SI7A 1KSLA 3MQKA 3M6VA 3LWRA 2APOA 2FRXA 1K8WA 1KSVA 3LWVA 1R3FA 3HAXA 1SGVA 2ISTA 4LABA 2RFKA 1KSKA 2I82A 3LWOA 2HVYA 2EY4A 1ZL3A 1Z2ZA 3HJYA 1PRZA 1V9KA 3LWQA 3U28A 3LWPA 1XPIA 1ZE2A 3M6UA 3M6WA 3UAIA 4LGTA 1ZE1A 3ZV0C 2AUSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QYU A;  1V9F A;  3DH3 A;  3HJW A;  2AB4 A;  1R3E A;  1KSL A;  3MQK A;  3LWR A;  2APO A;  1K8W A;  1KSV A;  3LWV A;  1R3F A;  3HAX A;  1SGV A;  2IST A;  4LAB A;  2RFK A;  1KSK A;  2I82 A;  3LWO A;  2HVY A;  2EY4 A;  1ZL3 A;  3HJY A;  1PRZ A;  1V9K A;  3LWQ A;  3LWP A;  3U28 A;  1XPI A;  1ZE2 A;  3UAI A;  4LGT A;  1ZE1 A;  3ZV0 C;  2AUS A; 
#chains in the Genus database with same CATH topology
 1QYU A;  2B78 A;  1V9F A;  1T5Y A;  1R3E A;  2CX0 A;  3MQK A;  1SQW A;  3IUW A;  2E5O A;  4TZ4 C;  1KSV A;  1XNE A;  4CI3 B;  3HAX A;  2IST A;  2RFK A;  2DP9 A;  2ANE A;  3HJY A;  3LWP A;  1ZBO A;  3M65 A;  1Q7H A;  3D79 A;  3M6X A;  1SB7 A;  2Z0T A;  2P38 A;  3VSE A;  2APO A;  1K8W A;  3LWV A;  4LAB A;  1WXW A;  1Z2Z A;  3LJC A;  3M6W A;  4LGT A;  1TE7 A;  1ZS7 A;  4CI1 B;  1WXX A;  4DMG A;  3DH3 A;  3HJW A;  2AB4 A;  1UOY A;  1SI7 A;  1KSL A;  3M6V A;  3LWR A;  4CI2 B;  1R3F A;  2J5T A;  1IT8 A;  1S04 A;  1KSK A;  3C0K A;  1V9K A;  3U28 A;  1XPI A;  3M4X A;  2Q07 A;  1SZW A;  2J5V A;  3LDF A;  2CWW A;  4Q1T A;  2CX1 A;  1J2B A;  2FRX A;  1SGV A;  2I82 A;  1WK2 A;  2KKU A;  3LWO A;  1ZL3 A;  2EY4 A;  2HVY A;  1IQ8 A;  1PRZ A;  3LWQ A;  1IT7 A;  1ZE2 A;  3M6U A;  3UAI A;  1ZE1 A;  3ZV0 C;  2AS0 A;  2AUS A; 
#chains in the Genus database with same CATH homology
 1QYU A;  3M6X A;  1SB7 A;  1V9F A;  3M4X A;  1SZW A;  3DH3 A;  3HJW A;  2AB4 A;  1R3E A;  1UOY A;  1SI7 A;  1KSL A;  3MQK A;  3M6V A;  3LWR A;  2APO A;  2FRX A;  1K8W A;  1KSV A;  3LWV A;  1R3F A;  3HAX A;  1SGV A;  2IST A;  4LAB A;  2RFK A;  1KSK A;  2I82 A;  3LWO A;  2HVY A;  2EY4 A;  1ZL3 A;  1Z2Z A;  3HJY A;  1PRZ A;  1V9K A;  3LWQ A;  3U28 A;  3LWP A;  1XPI A;  1ZE2 A;  3M6U A;  3M6W A;  3UAI A;  4LGT A;  1ZE1 A;  3ZV0 C;  2AUS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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