3HJYA

Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate rna
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
327
structure length
320
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
pubmed doi rcsb
molecule tags Isomerase/rna
source organism Pyrococcus furiosus
molecule keywords pseudouridine synthase CBf5
total genus 77
structure length 320
sequence length 327
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2009-05-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 3hjyA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3hjyA02
1R3FA 3LWVA 1V9KA 3HJWA 3ZV0C 3HJYA 2EY4A 3DH3A 3LWPA 1KSLA 3LWOA 2HVYA 3U28A 3LWRA 2RFKA 4LGTA 1KSKA 1XPIA 1ZL3A 1ZE2A 3HAXA 1PRZA 1R3EA 2ISTA 3MQKA 1KSVA 2AB4A 3UAIA 2APOA 4LABA 3LWQA 2AUSA 1SGVA 1V9FA 1QYUA 1K8WA 2I82A 1ZE1A
chains in the Genus database with same CATH superfamily
1WK2A 1R3FA 3M6UA 2Q07A 1TE7A 4CI2B 3ZV0C 3HJYA 4CI1B 4CI3B 3LJCA 2FRXA 3U28A 2RFKA 1KSKA 1SB7A 3VSEA 3M4XA 1IT8A 2AB4A 3UAIA 2APOA 1T5YA 3LDFA 1WXXA 1K8WA 2I82A 4TZ4C 4Q1TA 3IUWA 2B78A 1SZWA 2HVYA 3LWRA 1IQ8A 3HAXA 1ZBOA 1UOYA 2Z0TA 2E5OA 2CWWA 1KSVA 3C0KA 1IT7A 2P38A 3M6XA 4DMGA 2ISTA 3M65A 3LWVA 1V9KA 3HJWA 1SI7A 3M6VA 1SQWA 1XNEA 1J2BA 3LWPA 1ZS7A 1ZE2A 1R3EA 2CX1A 1S04A 3MQKA 3LWQA 2AUSA 1V9FA 2DP9A 2J5VA 1Z2ZA 1ZE1A 2EY4A 3DH3A 2CX0A 2ANEA 1KSLA 3LWOA 1WXWA 2J5TA 4LGTA 1ZL3A 1XPIA 1PRZA 4LABA 1SGVA 1QYUA 2AS0A 2KKUA 3D79A 1Q7HA 3M6WA
chains in the Genus database with same CATH topology
1R3FA 3LWVA 3M6UA 1V9KA 3HJWA 3ZV0C 3HJYA 2EY4A 1SI7A 3M6VA 3DH3A 3LWPA 1KSLA 3LWOA 1SZWA 2HVYA 2FRXA 3U28A 3LWRA 2RFKA 4LGTA 1KSKA 1SB7A 1XPIA 1ZL3A 1ZE2A 3HAXA 1UOYA 3M4XA 1PRZA 1R3EA 2ISTA 3MQKA 1KSVA 2AB4A 3UAIA 2APOA 4LABA 3LWQA 2AUSA 1SGVA 1V9FA 1Z2ZA 3M6XA 1QYUA 1K8WA 3M6WA 2I82A 1ZE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R3F A;  3LWV A;  1V9K A;  3HJW A;  3ZV0 C;  3HJY A;  2EY4 A;  3DH3 A;  3LWP A;  1KSL A;  3LWO A;  2HVY A;  3U28 A;  3LWR A;  2RFK A;  4LGT A;  1KSK A;  1XPI A;  1ZL3 A;  1ZE2 A;  3HAX A;  1PRZ A;  1R3E A;  2IST A;  3MQK A;  1KSV A;  2AB4 A;  3UAI A;  2APO A;  4LAB A;  3LWQ A;  2AUS A;  1SGV A;  1V9F A;  1QYU A;  1K8W A;  2I82 A;  1ZE1 A; 
#chains in the Genus database with same CATH topology
 1WK2 A;  1R3F A;  3M6U A;  2Q07 A;  1TE7 A;  4CI2 B;  3ZV0 C;  3HJY A;  4CI1 B;  4CI3 B;  3LJC A;  2FRX A;  3U28 A;  2RFK A;  1KSK A;  1SB7 A;  3VSE A;  3M4X A;  1IT8 A;  2AB4 A;  3UAI A;  2APO A;  1T5Y A;  3LDF A;  1WXX A;  1K8W A;  2I82 A;  4TZ4 C;  4Q1T A;  3IUW A;  2B78 A;  1SZW A;  2HVY A;  3LWR A;  1IQ8 A;  3HAX A;  1ZBO A;  1UOY A;  2Z0T A;  2E5O A;  2CWW A;  1KSV A;  3C0K A;  1IT7 A;  2P38 A;  3M6X A;  4DMG A;  2IST A;  3M65 A;  3LWV A;  1V9K A;  3HJW A;  1SI7 A;  3M6V A;  1SQW A;  1XNE A;  1J2B A;  3LWP A;  1ZS7 A;  1ZE2 A;  1R3E A;  2CX1 A;  1S04 A;  3MQK A;  3LWQ A;  2AUS A;  1V9F A;  2DP9 A;  2J5V A;  1Z2Z A;  1ZE1 A;  2EY4 A;  3DH3 A;  2CX0 A;  2ANE A;  1KSL A;  3LWO A;  1WXW A;  2J5T A;  4LGT A;  1ZL3 A;  1XPI A;  1PRZ A;  4LAB A;  1SGV A;  1QYU A;  2AS0 A;  2KKU A;  3D79 A;  1Q7H A;  3M6W A; 
#chains in the Genus database with same CATH homology
 1R3F A;  3LWV A;  3M6U A;  1V9K A;  3HJW A;  3ZV0 C;  3HJY A;  2EY4 A;  1SI7 A;  3M6V A;  3DH3 A;  3LWP A;  1KSL A;  3LWO A;  1SZW A;  2HVY A;  2FRX A;  3U28 A;  3LWR A;  2RFK A;  4LGT A;  1KSK A;  1SB7 A;  1XPI A;  1ZL3 A;  1ZE2 A;  3HAX A;  1UOY A;  3M4X A;  1PRZ A;  1R3E A;  2IST A;  3MQK A;  1KSV A;  2AB4 A;  3UAI A;  2APO A;  4LAB A;  3LWQ A;  2AUS A;  1SGV A;  1V9F A;  1Z2Z A;  3M6X A;  1QYU A;  1K8W A;  3M6W A;  2I82 A;  1ZE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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