3LWR | Genus

Total Genus 96

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	96
sequence length	327
structure length	317
Chain Sequence	RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Isomerase/rna binding protein/rna
source organism	Pyrococcus furiosus
publication title	Functional and Structural Impact of Target Uridine Substitutions on the H/ACA Ribonucleoprotein Particle Pseudouridine Synthase . pubmed doi rcsb
molecule keywords	Pseudouridine synthase Cbf5
total genus	96
structure length	317
sequence length	327
ec nomenclature	ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date	2010-02-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01472	PUA	PUA domain
A	PF01509	TruB_N	TruB family pseudouridylate synthase (N terminal domain)
A	PF08068	DKCLD	DKCLD (NUC011) domain
A	PF16198	TruB_C_2	tRNA pseudouridylate synthase B C-terminal domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.30.130.70	Mainly Beta	Roll	Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4	Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4	3lwrA01
3.30.2350.10	Alpha Beta	2-Layer Sandwich	Pseudouridine synthase	Pseudouridine synthase	3lwrA02

1K8WA 1ZE2A 1XPIA 2AUSA 3LWRA 1KSKA 3LWOA 1ZL3A 3HJYA 2RFKA 3MQKA 2APOA 2I82A 1KSLA 1ZE1A 2EY4A 1QYUA 1V9FA 4LABA 3HAXA 2ISTA 4LGTA 3U28A 1KSVA 1SGVA 3UAIA 3LWPA 1PRZA 2AB4A 2HVYA 1R3EA 3ZV0C 3DH3A 3LWQA 1V9KA 3HJWA 1R3FA 3LWVA
chains in the Genus database with same CATH superfamily

2CX0A 1IQ8A 2DP9A 2J5TA 1XPIA 4Q1TA 3M4XA 2FRXA 1KSKA 3HJYA 1WXXA 1KSLA 3M6VA 4LGTA 2CWWA 3D79A 2P38A 1R3FA 1ZBOA 1K8WA 1SB7A 2AUSA 3M6XA 2KKUA 2B78A 4CI2B 1XNEA 3LWOA 2RFKA 1UOYA 3LJCA 3MQKA 2APOA 3M65A 2I82A 2ANEA 2EY4A 1V9FA 3HAXA 1IT7A 1WK2A 1SGVA 2J5VA 1R3EA 3VSEA 3DH3A 3LDFA 3LWVA 1Q7HA 1TE7A 3M6UA 3C0KA 1J2BA 4DMGA 1ZL3A 4CI1B 1ZS7A 1SI7A 1QYUA 4LABA 1Z2ZA 2Z0TA 1SZWA 1KSVA 3UAIA 2Q07A 3LWPA 1T5YA 1PRZA 2E5OA 2AB4A 2HVYA 3ZV0C 1V9KA 1ZE2A 3LWRA 1WXWA 2AS0A 4CI3B 1ZE1A 1SQWA 1IT8A 2ISTA 3U28A 2CX1A 1S04A 4TZ4C 3IUWA 3LWQA 3HJWA 3M6WA
chains in the Genus database with same CATH topology

1K8WA 1SB7A 3M6UA 1XPIA 2AUSA 1ZE2A 3LWRA 3M6XA 3M4XA 2FRXA 1KSKA 3LWOA 1ZL3A 3HJYA 2RFKA 1UOYA 1SI7A 3MQKA 3HJWA 2APOA 2I82A 1KSLA 1ZE1A 2EY4A 3M6VA 1QYUA 1V9FA 4LABA 3HAXA 1Z2ZA 2ISTA 1SZWA 4LGTA 3U28A 1KSVA 1SGVA 3UAIA 1PRZA 2AB4A 2HVYA 1R3EA 3ZV0C 3DH3A 3LWQA 1V9KA 3LWPA 3M6WA 1R3FA 3LWVA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1K8W A;  1ZE2 A;  1XPI A;  2AUS A;  3LWR A;  1KSK A;  3LWO A;  1ZL3 A;  3HJY A;  2RFK A;  3MQK A;  2APO A;  2I82 A;  1KSL A;  1ZE1 A;  2EY4 A;  1QYU A;  1V9F A;  4LAB A;  3HAX A;  2IST A;  4LGT A;  3U28 A;  1KSV A;  1SGV A;  3UAI A;  3LWP A;  1PRZ A;  2AB4 A;  2HVY A;  1R3E A;  3ZV0 C;  3DH3 A;  3LWQ A;  1V9K A;  3HJW A;  1R3F A;  3LWV A; 
#chains in the Genus database with same CATH topology
 2CX0 A;  1IQ8 A;  2DP9 A;  2J5T A;  1XPI A;  4Q1T A;  3M4X A;  2FRX A;  1KSK A;  3HJY A;  1WXX A;  1KSL A;  3M6V A;  4LGT A;  2CWW A;  3D79 A;  2P38 A;  1R3F A;  1ZBO A;  1K8W A;  1SB7 A;  2AUS A;  3M6X A;  2KKU A;  2B78 A;  4CI2 B;  1XNE A;  3LWO A;  2RFK A;  1UOY A;  3LJC A;  3MQK A;  2APO A;  3M65 A;  2I82 A;  2ANE A;  2EY4 A;  1V9F A;  3HAX A;  1IT7 A;  1WK2 A;  1SGV A;  2J5V A;  1R3E A;  3VSE A;  3DH3 A;  3LDF A;  3LWV A;  1Q7H A;  1TE7 A;  3M6U A;  3C0K A;  1J2B A;  4DMG A;  1ZL3 A;  4CI1 B;  1ZS7 A;  1SI7 A;  1QYU A;  4LAB A;  1Z2Z A;  2Z0T A;  1SZW A;  1KSV A;  3UAI A;  2Q07 A;  3LWP A;  1T5Y A;  1PRZ A;  2E5O A;  2AB4 A;  2HVY A;  3ZV0 C;  1V9K A;  1ZE2 A;  3LWR A;  1WXW A;  2AS0 A;  4CI3 B;  1ZE1 A;  1SQW A;  1IT8 A;  2IST A;  3U28 A;  2CX1 A;  1S04 A;  4TZ4 C;  3IUW A;  3LWQ A;  3HJW A;  3M6W A; 
#chains in the Genus database with same CATH homology
 1K8W A;  1SB7 A;  3M6U A;  1XPI A;  2AUS A;  1ZE2 A;  3LWR A;  3M6X A;  3M4X A;  2FRX A;  1KSK A;  3LWO A;  1ZL3 A;  3HJY A;  2RFK A;  1UOY A;  1SI7 A;  3MQK A;  3HJW A;  2APO A;  2I82 A;  1KSL A;  1ZE1 A;  2EY4 A;  3M6V A;  1QYU A;  1V9F A;  4LAB A;  3HAX A;  1Z2Z A;  2IST A;  1SZW A;  4LGT A;  3U28 A;  1KSV A;  1SGV A;  3UAI A;  1PRZ A;  2AB4 A;  2HVY A;  1R3E A;  3ZV0 C;  3DH3 A;  3LWQ A;  1V9K A;  3LWP A;  3M6W A;  1R3F A;  3LWV A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3LWRA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations