3MQKA

Cbf5-nop10-gar1 complex binding with 17mer rna containing aca trinucleotide
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
328
structure length
328
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLWE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural and functional evidence of high specificity of Cbf5 for ACA trinucleotide.
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords tRNA pseudouridine synthase B
total genus 86
structure length 328
sequence length 328
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2010-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 3mqkA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3mqkA02
2AUSA 1SGVA 4LABA 3LWVA 1K8WA 1KSKA 3HAXA 2RFKA 1ZE1A 2HVYA 1KSLA 1R3FA 3MQKA 1ZE2A 3LWPA 1KSVA 1XPIA 4LGTA 2EY4A 3LWRA 3ZV0C 1V9FA 2APOA 3HJYA 1PRZA 2I82A 3UAIA 1R3EA 3LWOA 1V9KA 2AB4A 3LWQA 3DH3A 3HJWA 1ZL3A 1QYUA 3U28A 2ISTA
chains in the Genus database with same CATH superfamily
4CI2B 1ZBOA 3LWVA 1SZWA 2ANEA 3LDFA 3HAXA 2RFKA 1ZE1A 2Z0TA 4DMGA 1ZE2A 2J5TA 3LJCA 1KSVA 4LGTA 1S04A 2Q07A 2I82A 2CX1A 4CI3B 3UAIA 1Z2ZA 2AS0A 1V9KA 2AB4A 2DP9A 3LWQA 1SB7A 3DH3A 1SQWA 1SGVA 1SI7A 1K8WA 1UOYA 1WXXA 1TE7A 2FRXA 1IT7A 3M6VA 3C0KA 3M6WA 2EY4A 1V9FA 3HJYA 2P38A 3M4XA 4TZ4C 3LWOA 1R3EA 1J2BA 1ZL3A 1QYUA 3LWPA 3M6XA 2CX0A 1XNEA 3VSEA 2J5VA 1T5YA 1R3FA 3M65A 1IQ8A 1Q7HA 3LWRA 1ZS7A 3IUWA 4Q1TA 4CI1B 2KKUA 2CWWA 2E5OA 2AUSA 4LABA 1KSKA 2B78A 2HVYA 1KSLA 3MQKA 1WXWA 1XPIA 1IT8A 3ZV0C 2APOA 3M6UA 1PRZA 3D79A 3HJWA 3U28A 2ISTA 1WK2A
chains in the Genus database with same CATH topology
3M6XA 2AUSA 1SGVA 4LABA 1SI7A 3LWVA 1K8WA 1KSKA 1UOYA 1SZWA 3U28A 2FRXA 3HAXA 2RFKA 1ZE1A 2HVYA 1KSLA 3M6VA 1R3FA 3M6WA 3MQKA 1ZE2A 1KSVA 1XPIA 4LGTA 2EY4A 3LWRA 3ZV0C 1V9FA 2APOA 3M6UA 3HJYA 1PRZA 2I82A 3UAIA 3M4XA 1R3EA 3LWOA 1Z2ZA 1V9KA 2AB4A 3LWQA 1SB7A 3HJWA 3DH3A 1ZL3A 1QYUA 3LWPA 2ISTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AUS A;  1SGV A;  4LAB A;  3LWV A;  1K8W A;  1KSK A;  3HAX A;  2RFK A;  1ZE1 A;  2HVY A;  1KSL A;  1R3F A;  3MQK A;  1ZE2 A;  3LWP A;  1KSV A;  1XPI A;  4LGT A;  2EY4 A;  3LWR A;  3ZV0 C;  1V9F A;  2APO A;  3HJY A;  1PRZ A;  2I82 A;  3UAI A;  1R3E A;  3LWO A;  1V9K A;  2AB4 A;  3LWQ A;  3DH3 A;  3HJW A;  1ZL3 A;  1QYU A;  3U28 A;  2IST A; 
#chains in the Genus database with same CATH topology
 4CI2 B;  1ZBO A;  3LWV A;  1SZW A;  2ANE A;  3LDF A;  3HAX A;  2RFK A;  1ZE1 A;  2Z0T A;  4DMG A;  1ZE2 A;  2J5T A;  3LJC A;  1KSV A;  4LGT A;  1S04 A;  2Q07 A;  2I82 A;  2CX1 A;  4CI3 B;  3UAI A;  1Z2Z A;  2AS0 A;  1V9K A;  2AB4 A;  2DP9 A;  3LWQ A;  1SB7 A;  3DH3 A;  1SQW A;  1SGV A;  1SI7 A;  1K8W A;  1UOY A;  1WXX A;  1TE7 A;  2FRX A;  1IT7 A;  3M6V A;  3C0K A;  3M6W A;  2EY4 A;  1V9F A;  3HJY A;  2P38 A;  3M4X A;  4TZ4 C;  3LWO A;  1R3E A;  1J2B A;  1ZL3 A;  1QYU A;  3LWP A;  3M6X A;  2CX0 A;  1XNE A;  3VSE A;  2J5V A;  1T5Y A;  1R3F A;  3M65 A;  1IQ8 A;  1Q7H A;  3LWR A;  1ZS7 A;  3IUW A;  4Q1T A;  4CI1 B;  2KKU A;  2CWW A;  2E5O A;  2AUS A;  4LAB A;  1KSK A;  2B78 A;  2HVY A;  1KSL A;  3MQK A;  1WXW A;  1XPI A;  1IT8 A;  3ZV0 C;  2APO A;  3M6U A;  1PRZ A;  3D79 A;  3HJW A;  3U28 A;  2IST A;  1WK2 A; 
#chains in the Genus database with same CATH homology
 3M6X A;  2AUS A;  1SGV A;  4LAB A;  1SI7 A;  3LWV A;  1K8W A;  1KSK A;  1UOY A;  1SZW A;  3U28 A;  2FRX A;  3HAX A;  2RFK A;  1ZE1 A;  2HVY A;  1KSL A;  3M6V A;  1R3F A;  3M6W A;  3MQK A;  1ZE2 A;  1KSV A;  1XPI A;  4LGT A;  2EY4 A;  3LWR A;  3ZV0 C;  1V9F A;  2APO A;  3M6U A;  3HJY A;  1PRZ A;  2I82 A;  3UAI A;  3M4X A;  1R3E A;  3LWO A;  1Z2Z A;  1V9K A;  2AB4 A;  3LWQ A;  1SB7 A;  3HJW A;  3DH3 A;  1ZL3 A;  1QYU A;  3LWP A;  2IST A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...