3MQKA

Cbf5-nop10-gar1 complex binding with 17mer rna containing aca trinucleotide
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
328
structure length
328
Chain Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLWE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and functional evidence of high specificity of Cbf5 for ACA trinucleotide.
pubmed doi rcsb
molecule tags Isomerase/rna binding protein/rna
source organism Pyrococcus furiosus
molecule keywords tRNA pseudouridine synthase B
total genus 86
structure length 328
sequence length 328
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date 2010-04-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.70 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 3mqkA01
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3mqkA02
1KSLA 3MQKA 1QYUA 3DH3A 1ZE2A 1KSVA 4LABA 1SGVA 1R3EA 2ISTA 3HAXA 3LWQA 3LWOA 2AUSA 3LWVA 2HVYA 3HJWA 1PRZA 2RFKA 1V9FA 1XPIA 2I82A 1R3FA 4LGTA 1V9KA 2EY4A 1ZL3A 3U28A 3ZV0C 3UAIA 2APOA 3LWRA 1K8WA 1ZE1A 3LWPA 1KSKA 2AB4A 3HJYA
chains in the Genus database with same CATH superfamily
1IT7A 1QYUA 2CX1A 2ISTA 3LWVA 1PRZA 1SQWA 1IQ8A 4TZ4C 3VSEA 4CI3B 1ZL3A 3D79A 3IUWA 1ZBOA 2AB4A 3HJYA 1S04A 2CWWA 3C0KA 1ZE2A 1Z2ZA 3M6WA 1SGVA 1IT8A 2J5TA 2DP9A 1SZWA 2FRXA 2I82A 1R3FA 4LGTA 1V9KA 3M6UA 1SI7A 3U28A 2ANEA 2P38A 1UOYA 3LWRA 1T5YA 2Z0TA 1KSKA 1Q7HA 4CI2B 2Q07A 1KSLA 3DH3A 3M65A 4LABA 2AS0A 3HAXA 1WXWA 3HJWA 1J2BA 2KKUA 1XPIA 2J5VA 3LJCA 3M4XA 3M6VA 1SB7A 2EY4A 3UAIA 3ZV0C 1WK2A 2APOA 1ZE1A 4Q1TA 4CI1B 3MQKA 1KSVA 3LDFA 1R3EA 1WXXA 3LWQA 3LWOA 2AUSA 2E5OA 2HVYA 2B78A 2RFKA 1V9FA 4DMGA 1ZS7A 1XNEA 1K8WA 3LWPA 2CX0A 3M6XA 1TE7A
chains in the Genus database with same CATH topology
1KSLA 3MQKA 1QYUA 3DH3A 1Z2ZA 1ZE2A 1KSVA 3M6WA 4LABA 2AB4A 1SGVA 1R3EA 2ISTA 3HAXA 3LWQA 3LWOA 2AUSA 3LWVA 2HVYA 3HJWA 1PRZA 1SZWA 2RFKA 1V9FA 2FRXA 1XPIA 2I82A 1R3FA 4LGTA 1V9KA 3M4XA 3M6VA 1SB7A 3M6UA 2EY4A 1SI7A 1ZL3A 3U28A 3ZV0C 3UAIA 1UOYA 2APOA 3LWRA 1K8WA 1ZE1A 3LWPA 1KSKA 3M6XA 3HJYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KSL A;  3MQK A;  1QYU A;  3DH3 A;  1ZE2 A;  1KSV A;  4LAB A;  1SGV A;  1R3E A;  2IST A;  3HAX A;  3LWQ A;  3LWO A;  2AUS A;  3LWV A;  2HVY A;  3HJW A;  1PRZ A;  2RFK A;  1V9F A;  1XPI A;  2I82 A;  1R3F A;  4LGT A;  1V9K A;  2EY4 A;  1ZL3 A;  3U28 A;  3ZV0 C;  3UAI A;  2APO A;  3LWR A;  1K8W A;  1ZE1 A;  3LWP A;  1KSK A;  2AB4 A;  3HJY A; 
#chains in the Genus database with same CATH topology
 1IT7 A;  1QYU A;  2CX1 A;  2IST A;  3LWV A;  1PRZ A;  1SQW A;  1IQ8 A;  4TZ4 C;  3VSE A;  4CI3 B;  1ZL3 A;  3D79 A;  3IUW A;  1ZBO A;  2AB4 A;  3HJY A;  1S04 A;  2CWW A;  3C0K A;  1ZE2 A;  1Z2Z A;  3M6W A;  1SGV A;  1IT8 A;  2J5T A;  2DP9 A;  1SZW A;  2FRX A;  2I82 A;  1R3F A;  4LGT A;  1V9K A;  3M6U A;  1SI7 A;  3U28 A;  2ANE A;  2P38 A;  1UOY A;  3LWR A;  1T5Y A;  2Z0T A;  1KSK A;  1Q7H A;  4CI2 B;  2Q07 A;  1KSL A;  3DH3 A;  3M65 A;  4LAB A;  2AS0 A;  3HAX A;  1WXW A;  3HJW A;  1J2B A;  2KKU A;  1XPI A;  2J5V A;  3LJC A;  3M4X A;  3M6V A;  1SB7 A;  2EY4 A;  3UAI A;  3ZV0 C;  1WK2 A;  2APO A;  1ZE1 A;  4Q1T A;  4CI1 B;  3MQK A;  1KSV A;  3LDF A;  1R3E A;  1WXX A;  3LWQ A;  3LWO A;  2AUS A;  2E5O A;  2HVY A;  2B78 A;  2RFK A;  1V9F A;  4DMG A;  1ZS7 A;  1XNE A;  1K8W A;  3LWP A;  2CX0 A;  3M6X A;  1TE7 A; 
#chains in the Genus database with same CATH homology
 1KSL A;  3MQK A;  1QYU A;  3DH3 A;  1Z2Z A;  1ZE2 A;  1KSV A;  3M6W A;  4LAB A;  2AB4 A;  1SGV A;  1R3E A;  2IST A;  3HAX A;  3LWQ A;  3LWO A;  2AUS A;  3LWV A;  2HVY A;  3HJW A;  1PRZ A;  1SZW A;  2RFK A;  1V9F A;  2FRX A;  1XPI A;  2I82 A;  1R3F A;  4LGT A;  1V9K A;  3M4X A;  3M6V A;  1SB7 A;  3M6U A;  2EY4 A;  1SI7 A;  1ZL3 A;  3U28 A;  3ZV0 C;  3UAI A;  1UOY A;  2APO A;  3LWR A;  1K8W A;  1ZE1 A;  3LWP A;  1KSK A;  3M6X A;  3HJY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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