3UAIA

Structure of the shq1-cbf5-nop10-gar1 complex from saccharomyces cerevisiae
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
361
structure length
357
Chain Sequence
DTSEWPLLLKNFDKLLVRSGHYTPIPAGSSPLKRDLKSYISSGVINLDKPSNPSSHEVVAWIKRILRCEKTGHSGTLDPKVTGCLIVCIDRATRLVKSQQGAGKEYVCIVRLHDALKDEKDLGRSLENLTGALFQRPPLKRQLRVRTIYESNLIEFDNKRNLGVFWASCEAGTYMRTLCVHLGMLLGVGGHMQELRRVRSGALSENDNMVTLHDVMDAQWVYDNTRDESYLRSIIQPLETLLVGYKRIVVKDSAVNAVCYGAKLMIPGLLRYEEGIELYDEIVLITTKGEAIAVAIAQMSTVDLASCDHGVVASVKRCIMERDLYPRRWGLGPVAQKKKQMKADGKLDKYGRVNENT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Shq1-Cbf5-Nop10-Gar1 complex and implications for H/ACA RNP biogenesis and dyskeratosis congenita
pubmed doi rcsb
molecule tags Isomerase/chaperone
source organism Saccharomyces cerevisiae
molecule keywords H/ACA ribonucleoprotein complex subunit 4
total genus 94
structure length 357
sequence length 361
ec nomenclature ec 5.4.99.-:
pdb deposition date 2011-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01472 PUA PUA domain
A PF01509 TruB_N TruB family pseudouridylate synthase (N terminal domain)
A PF08068 DKCLD DKCLD (NUC011) domain
A PF16198 TruB_C_2 tRNA pseudouridylate synthase B C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.130.10 Mainly Beta Roll Archaeosine Trna-guanine Transglycosylase; Chain: A, domain 4 PUA domain 3uaiA02
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3uaiA01
4LABA 2J5TA 1ZE2A 1ZS7A 2HVYA 2CX1A 1R3FA 2APOA 3LWRA 2B78A 3HJWA 1WXWA 1V9FA 3UAIA 2I82A 2Q07A 2AUSA 1SQWA 3HAXA 3LWVA 1IT8A 1QYUA 1PRZA 1ZE1A 1IQ8A 2ISTA 2RFKA 3C0KA 1K8WA 1J2BA 3LDFA 1ZL3A 1KSKA 1IT7A 1T5YA 2P38A 4DMGA 2CX0A 4Q1TA 3MQKA 2AS0A 1KSLA 1V9KA 1XPIA 2EY4A 4LGTA 3U28A 3LWOA 3LWPA 3LWQA 1Q7HA 2J5VA 3D79A 2CWWA 1SGVA 2AB4A 3DH3A 1R3EA 3HJYA 1WXXA 3VSEA 1KSVA
chains in the Genus database with same CATH superfamily
3LWRA 1WXWA 2AUSA 1SQWA 1IT8A 2ISTA 2RFKA 3M65A 4CI3B 1K8WA 1J2BA 1XNEA 3LDFA 2P38A 4Q1TA 2Z0TA 3LWPA 2AB4A 2KKUA 1UOYA 3LWVA 1PRZA 1TE7A 3ZV0C 2J5TA 1ZE2A 1ZS7A 2HVYA 1R3FA 1Z2ZA 3HJWA 1V9FA 1IT7A 1SB7A 2AS0A 1KSLA 4CI2B 1Q7HA 3LJCA 1WXXA 4LABA 2E5OA 4CI1B 1WK2A 3M6VA 4TZ4C 1ZE1A 1ZBOA 1IQ8A 3C0KA 3IUWA 3M6XA 1S04A 1KSKA 1T5YA 3M6WA 2CX0A 1XPIA 3LWOA 4LGTA 2DP9A 3M6UA 2J5VA 3D79A 2CWWA 1SGVA 3DH3A 1R3EA 3HJYA 2APOA 2CX1A 2ANEA 2B78A 2I82A 3UAIA 2Q07A 3M4XA 3HAXA 1QYUA 2FRXA 1SZWA 1ZL3A 4DMGA 3MQKA 1V9KA 2EY4A 3U28A 3LWQA 1SI7A 3VSEA 1KSVA
chains in the Genus database with same CATH topology
4LABA 2J5TA 1ZE2A 1ZS7A 2HVYA 2CX1A 1R3FA 2APOA 3LWRA 1Z2ZA 2B78A 3HJWA 1WXWA 1V9FA 3UAIA 2I82A 2Q07A 2AUSA 1SQWA 3HAXA 3LWVA 1IT8A 1QYUA 1PRZA 1ZE1A 1IQ8A 1SZWA 2ISTA 2RFKA 3C0KA 1K8WA 1J2BA 3LDFA 1ZL3A 1KSKA 1IT7A 1SB7A 1T5YA 2P38A 4DMGA 2CX0A 4Q1TA 3MQKA 2AS0A 1KSLA 1V9KA 1XPIA 2EY4A 4LGTA 3U28A 3LWOA 3LWPA 3LWQA 1SI7A 1Q7HA 2J5VA 3D79A 2CWWA 1SGVA 2AB4A 3DH3A 1R3EA 3HJYA 1WXXA 3VSEA 1KSVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LAB A;  2J5T A;  1ZE2 A;  1ZS7 A;  2HVY A;  2CX1 A;  1R3F A;  2APO A;  3LWR A;  2B78 A;  3HJW A;  1WXW A;  1V9F A;  3UAI A;  2I82 A;  2Q07 A;  2AUS A;  1SQW A;  3HAX A;  3LWV A;  1IT8 A;  1QYU A;  1PRZ A;  1ZE1 A;  1IQ8 A;  2IST A;  2RFK A;  3C0K A;  1K8W A;  1J2B A;  3LDF A;  1ZL3 A;  1KSK A;  1IT7 A;  1T5Y A;  2P38 A;  4DMG A;  2CX0 A;  4Q1T A;  3MQK A;  2AS0 A;  1KSL A;  1V9K A;  1XPI A;  2EY4 A;  4LGT A;  3U28 A;  3LWO A;  3LWP A;  3LWQ A;  1Q7H A;  2J5V A;  3D79 A;  2CWW A;  1SGV A;  2AB4 A;  3DH3 A;  1R3E A;  3HJY A;  1WXX A;  3VSE A;  1KSV A; 
#chains in the Genus database with same CATH topology
 3LWR A;  1WXW A;  2AUS A;  1SQW A;  1IT8 A;  2IST A;  2RFK A;  3M65 A;  4CI3 B;  1K8W A;  1J2B A;  1XNE A;  3LDF A;  2P38 A;  4Q1T A;  2Z0T A;  3LWP A;  2AB4 A;  2KKU A;  1UOY A;  3LWV A;  1PRZ A;  1TE7 A;  3ZV0 C;  2J5T A;  1ZE2 A;  1ZS7 A;  2HVY A;  1R3F A;  1Z2Z A;  3HJW A;  1V9F A;  1IT7 A;  1SB7 A;  2AS0 A;  1KSL A;  4CI2 B;  1Q7H A;  3LJC A;  1WXX A;  4LAB A;  2E5O A;  4CI1 B;  1WK2 A;  3M6V A;  4TZ4 C;  1ZE1 A;  1ZBO A;  1IQ8 A;  3C0K A;  3IUW A;  3M6X A;  1S04 A;  1KSK A;  1T5Y A;  3M6W A;  2CX0 A;  1XPI A;  3LWO A;  4LGT A;  2DP9 A;  3M6U A;  2J5V A;  3D79 A;  2CWW A;  1SGV A;  3DH3 A;  1R3E A;  3HJY A;  2APO A;  2CX1 A;  2ANE A;  2B78 A;  2I82 A;  3UAI A;  2Q07 A;  3M4X A;  3HAX A;  1QYU A;  2FRX A;  1SZW A;  1ZL3 A;  4DMG A;  3MQK A;  1V9K A;  2EY4 A;  3U28 A;  3LWQ A;  1SI7 A;  3VSE A;  1KSV A; 
#chains in the Genus database with same CATH homology
 4LAB A;  2J5T A;  1ZE2 A;  1ZS7 A;  2HVY A;  2CX1 A;  1R3F A;  2APO A;  3LWR A;  1Z2Z A;  2B78 A;  3HJW A;  1WXW A;  1V9F A;  3UAI A;  2I82 A;  2Q07 A;  2AUS A;  1SQW A;  3HAX A;  3LWV A;  1IT8 A;  1QYU A;  1PRZ A;  1ZE1 A;  1IQ8 A;  1SZW A;  2IST A;  2RFK A;  3C0K A;  1K8W A;  1J2B A;  3LDF A;  1ZL3 A;  1KSK A;  1IT7 A;  1SB7 A;  1T5Y A;  2P38 A;  4DMG A;  2CX0 A;  4Q1T A;  3MQK A;  2AS0 A;  1KSL A;  1V9K A;  1XPI A;  2EY4 A;  4LGT A;  3U28 A;  3LWO A;  3LWP A;  3LWQ A;  1SI7 A;  1Q7H A;  2J5V A;  3D79 A;  2CWW A;  1SGV A;  2AB4 A;  3DH3 A;  1R3E A;  3HJY A;  1WXX A;  3VSE A;  1KSV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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